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*  Characterization of the Extrinsic Apoptotic Pathway in the Basal Chordate Amphioxus | Science Signaling
... which bound to the adaptor proteins CRADD or TRAF6 (tumor necrosis factor receptor-associated factor 6) to convey distinct ... especially given that amphioxus contains 14 DR proteins and hundreds of death domain (DD)-containing adaptor proteins. To ... Science Signaling. 14 Sep 2010. : ra66 Death domain-dependent signaling in the basal chordate amphioxus suggests that extrinsic ... Science Signaling. 14 Sep 2010. : ra66 Death domain-dependent signaling in the basal chordate amphioxus suggests that extrinsic ...
http://stke.sciencemag.org/content/3/139/ra66
*  Anti-RAIDD antibody [EPR1640Y] Recombinant (ab52621) | Abcam
Death adaptor molecule RAIDD antibody. *Death domain containing protein CRADD antibody. *Death domain-containing protein CRADD ... In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. ... Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. ... Proteins and Peptides. Proteomics tools. Agonists, activators, antagonists and inhibitors. Lysates. Multiplex miRNA assays. By ...
https://www.abcam.com/raidd-antibody-epr1640y-ab52621.html
*  Apoptosis: cell 'death' reveals creation - creation.com
Intracellular 'adaptor' proteins (such as TRADD, FADD/MORT1, RIP, RAIDD/CRADD and Reaper) have death domain homologous regions* ... that bind to the DDs of Fas and TNFR1,16-19 thereby relaying signals to a further series of proteins, variously known as the ... The first line proteins are those containing a so-called 'death domain' (DD). Some of these are trans-membrane proteins with a ... Rb, (retinoblastoma protein) and other functionally related proteins, are critical regulators of cell proliferation and ...
https://creation.com/apoptosis-cell-death-reveals-creation
*  CARD Signaling Adaptor Proteins | Colorado PROFILES
CRADD Signaling Adaptor Protein. *Nod1 Signaling Adaptor Protein. *Nod2 Signaling Adaptor Protein ... CARD Signaling Adaptor Proteins*CARD Signaling Adaptor Proteins. *Caspase Activation and Recruitment Domain Signaling Proteins ... "CARD Signaling Adaptor Proteins" by people in this website by year, and whether "CARD Signaling Adaptor Proteins" was a major ... "CARD Signaling Adaptor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH ( ...
https://profiles.ucdenver.edu/display/223710
*  重组人RAIDD蛋白(ab78880)| Abcam中国
Death adaptor molecule RAIDD. *Death domain containing protein CRADD. *Death domain-containing protein CRADD ... In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. ... Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. ... The Universal Protein Resource (UniProt) in 2010. Nucleic Acids Res. 38:D142-D148 (2010) . ...
http://www.abcam.cn/recombinant-human-raidd-protein-ab78880.html
*  CARD domain - Wikipedia
Mitochondrial antiviral-signaling protein also known as CARD adapter inducing interferon-beta (Cardif/IPS-1) [13] CRADD: ... The adaptor protein VISA further activates the IKK-protein-kinase family members. Although the canonical IKK family members ... Death adaptor molecule RAIDD-2 [15] RIG-I: Retinoic acid-inducible gene 1 protein, also known as DEAD-box protein 58 (DDX58) [ ... Recently, studies on the NLR protein Ipaf-1 have provided insight into how CARD proteins participate in the immune response. ...
https://en.wikipedia.org/wiki/CARD_domain
*  RIPK1 - Wikipedia
To activate IKK, TAB2 and TAB3 adaptor proteins recruit TAK1 or MEKK3, which phosphorylate the complex. This results in the ... Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins". The ... Ahmad M, Srinivasula SM, Wang L, Talanian RV, Litwack G, Fernandes-Alnemri T, Alnemri ES (February 1997). "CRADD, a novel human ... Chen D, Li X, Zhai Z, Shu HB (May 2002). "A novel zinc finger protein interacts with receptor-interacting protein (RIP) and ...
https://en.wikipedia.org/wiki/RIPK1
*  CRADD - CRADD Protein | CRADD cDNA | Recombinant CRADD Protein Protein
Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain) ... Bioclone provides recombinant protein codon optimized cDNA clone for P78560 CRADD Death domain-containing protein CRADD ( ... Signal Transduction. *CD Marker. *Drug metabolism * Neuroscience *Common Disease. *Cytokine. *Allergy & Toxin Protein. * much ... CRADD Protein Source. Recombinant protein.. Recombinant CRADD Protein Applications. Western Blot, may be used for other ...
http://www.bioclone.us/33-Human-Stem-cell-CRADD-Protein-Human-Recombinant-CRADD-CRADD-cDNA.html
*  Genetics of Recessive Cognitive Disorders
2000) 14‐3‐3 interacts with regulator of G protein signaling proteins and modulates their activity. The Journal of Biological ... 1997) CRADD, a novel human apoptotic adaptor molecule for caspase‐2, and FasL/tumor necrosis factor receptor‐interacting ... 2005) A human proteinprotein interaction network: a resource for annotating the proteome. Cell 122 (6): 957-968. ... Al‐Tawashi A, Jung SY, Liu D, Su B and Qin J (2012) Protein implicated in nonsyndromic mental retardation regulates protein ...
http://www.els.net/WileyCDA/ElsArticle/refId-a0025835.html
*  CRADD protein (Pongo abelii) - STRING interaction network
CRADD. Death domain-containing protein CRADD ; Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor- ... interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex (By ... CRADD. ANK1. ENSPPYP00000005515. ENSPPYP00000020798. Death domain-containing protein CRADD ; Apoptotic adaptor molecule ... CRADD. ANKRD44. ENSPPYP00000005515. ENSPPYP00000014573. Death domain-containing protein CRADD ; Apoptotic adaptor molecule ...
https://string-db.org/network/9601.ENSPPYP00000005515
*  anti-Caspase 2 Primary Antibodies
... revealed a homozygous frameshift variant in CRADD, which encodes an adaptor protein that interacts with PIDD and caspase-2 to ... axon regeneration promoted by suppression of CASP2 and CASP6 is CNTF-dependent and mediated through the JAK/STAT signalling ... Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may ... neural precursor cell expressed developmentally down-regulated protein 2 , protein phosphatase 1, regulatory subunit 57 , ...
https://www.antikoerper-online.de/apoptose-pathway-9/caspase-2-antibody-2843/
*  Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid...
CRADD. CASP2 and RIPK1 domain containing adaptor with death domain. 86.0764. 598.6941 ... proteins, death domain proteins, TRAF (TNF receptor-associated factor) domain proteins, and caspases. FOXO1 was found to be the ... Danvers, MA), FOXO1 (1:1000, Cell Signaling Technology, Inc. Danvers, MA), CDKN1A (1:1000, Cell Signaling Technology, Inc. ... Equal amounts of protein were resolved on 12% SDS-PAGE gels, and then transferred to a PVDF membrane (Millipore, Bedford, MA). ...
https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-12-182
*  Death Receptors: Signaling and Modulation | Science
1); this is supported by nuclear magnetic resonance structure analysis and mutagenesis studies (28). An adapter protein called ... TNFR1 can engage an adapter called RAIDD or CRADD (50). RAIDD binds through a death domain to the death domain of RIP and ... TRADD functions as a platform adapter that recruits several signaling molecules to the activated receptor: TNFR-associated ... A family of viral proteins called vFLIPs and a related cellular protein called cFLIP (also called Casper, I-FLICE, FLAME, or ...
https://science.sciencemag.org/content/281/5381/1305?ijkey=e6223aa6ab588ffdde08c57a6d92ff67297800e8&keytype2=tf_ipsecsha
*  B cells biology in sepsis - Oxford Talks
DR adaptor proteins (CRADD, PIDD1 and FADD), CFLAR, CASP8 and CASP10. Thus, in sepsis, there are major alternations in B cell ... highlight changes in major canonical signalling pathways of cellular function, metabolism, in both innate and adaptive immune ... pro-apoptotic BCL2 proteins (APAF1, HTRA2, HIP1 and BOK) and death Receptor pathway with higher expression of plasma membrane ... infection to sepsis represents an inflection point in the race between the human immune system devised to detect danger signals ...
https://talks.ox.ac.uk/talks/id/b9de5560-8385-4a97-b7ea-de120ad383f2/
*  IMP: Integrative Multi-species Prediction
signal transducer and activator of transcription 2, 113kDa. 0.294. BNIP3L. BCL2/adenovirus E1B 19kDa interacting protein 3-like ... CRADD. CASP2 and RIPK1 domain containing adaptor with death domain. 0.250. NOSTRIN. nitric oxide synthase trafficker. 0.245. ... signal transducer and activator of transcription 3 (acute-phase response factor). 0.014. ...
http://imp.princeton.edu/predictions/process/human-context-global/2554/?gene=20752
*  Genatlas sheet
adaptor molecule CRADD coordinates IKBKE and IRF7 interaction to ensure efficient expression of type I interferon ... PROTEIN. PHYSICAL PROPERTIES STRUCTURE motifs/domains * the last three C-terminal lysine sites (positions 444, 446, and 452) of ... signaling a component * component of VAF (virus-activated factor) which is composed of IRF7, IRF3, and the transcriptional ... protein * interacting with IRF3 in a biologically active complex. * substrate for TRAF6 E3 ligase and IRF7 is ubiquitinated by ...
http://genatlas.medecine.univ-paris5.fr/fiche.php?symbol=IRF7
*  Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia | Journal of...
We hypothesized that TLR2 signaling might mediate the cell death process as well. To test this hypothesis, we investigated HSV- ... We demonstrate here that HSV induces an apoptotic response in microglial cells which is mediated through TLR2 signaling. ... Cradd. CASP2 and RIPK1 adaptor domain containing protein. -1.54. -6.32. Fadd. Fas-associated death domain ... TLR2 signaling mediates HSV-induced apoptosis in murine microglia. To test the hypothesis that TLR2 signaling is involved in ...
https://jneuroinflammation.biomedcentral.com/articles/10.1186/1742-2094-4-11
*  IMP: Integrative Multi-species Prediction
CRADD. CASP2 and RIPK1 domain containing adaptor with death domain. 0.532. MET. met proto-oncogene (hepatocyte growth factor ... protein kinase, DNA-activated, catalytic polypeptide. 0.369. STAT3. signal transducer and activator of transcription 3 (acute- ... protein autoprocessing. GO:0016540. Processing which a protein carries out itself. This involves actions such as the autolytic ... Highlight genes with functional analogs involved in "protein autoprocessing" (in gray). Name. Description. Probability. Func ...
http://imp.princeton.edu/predictions/process/human-context-global/12956/?gene=925
*  Megalencephaly disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
CRADD CASP2 And RIPK1 Domain Containing Adaptor With Death Domain. Protein Coding. 16.67. GeneCards inferred via :. ... regulation of protein kinase B signaling. GO:0051896 9.52. MTOR STK11 12. astrocyte differentiation. GO:0048708 9.48. EIF2B5 ... protein kinase activator activity. GO:0030295 8.8. PIK3CA STK11 STRADA 4. protein binding. GO:0005515 10.19. AKT3 CCND2 CRADD ... STE20-Related Kinase Adaptor Alpha. Protein Coding. 45.61. GeneCards inferred via :. Disorders Publications Summaries Variants ...
https://www.malacards.org/card/megalencephaly
*  Anti-GAPDH 抗体 - Loading Control (ab9485) 使用論文
Bugaj LJ et al. Optogenetic protein clustering and signaling activation in mammalian cells. Nat Methods 10:249-52 (2013). ... Qiao H et al. The adaptor CRADD/RAIDD controls activation of endothelial cells by proinflammatory stimuli. J Biol Chem 289: ... Mitchell CJ et al. Consumption of Milk Protein or Whey Protein Results in a Similar Increase in Muscle Protein Synthesis in ... Mitchell CJ et al. Minimal dose of milk protein concentrate to enhance the anabolic signalling response to a single bout of ...
http://www.abcam.co.jp/gapdh-antibody-loading-control-ab9485-references.html
*  Immunogenetics of Hashimoto's thyroiditis | Springer for Research & Development
Lynch RA, Wagoner L, Li S, Sparks L, Molkentin J, Dorn GW: Novel and nondetected human signaling protein polymorphisms. Physiol ... a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP. Cancer ... Ahmad M, Srinivasula SM, Wang L, Talanian RV, Litwack G, Fernandes-Alnemri T, Alnemri ES: CRADD, ... It may be that the amino acid change at codon 17 of the signal peptide could alter the function of the signal peptide to direct ...
https://rd.springer.com/article/10.1186/1740-2557-2-1
*  Lissencephaly disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials
Homozygous null variant in CRADD, encoding an adaptor protein that mediates apoptosis, is associated with lissencephaly. ( ... reelin-mediated signaling pathway. GO:0038026 9.43. LRP8 RELN VLDLR 31. layer formation in cerebral cortex. GO:0021819 9.26. ... protein O-linked mannosylation. GO:0035269 9.61. FKRP FKTN TMEM5 21. cellular response to cholesterol. GO:0071397 9.6. DAG1 ... protein localization to synapse. GO:0035418 9.59. CDK5 RELN 23. vesicle transport along microtubule. GO:0047496 9.58. NDE1 ...
http://www.malacards.org/card/lissencephaly
*  Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2...
Anti-apoptotic signalling that may increase cell survival and promote tumourigenesis was also evident. This study has further ... cell cycle data and p53 protein expression identified a number of genes that are linked to these biological outcomes, thereby ... CRADD. AL832705. CASP2 and RIPK1 domain containing adaptor with death domain. induction of apoptosis via death domain receptors ... Increased cellular p53 protein levels in response to various genotoxic agents are due mainly to an increase in p53 protein ...
https://0-bmcgenomics-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2164-7-260
*  METHODS AND MATERIALS FOR ASSESSING A MAMMAL'S SUSCEPTIBILITY FOR VENOUS THROMBOEMBOLISM - Patent application
... containing adaptor protein TLR1 7096 toll-like receptor 1 4 4p14 38474271 38482807 7 5 5 TLR10 81793 toll-like receptor 10 4 ... CRADD 8738 CASP2 and RIPK1 domain containing 12 12q21.33-q23.1 92595282 92768663 48 48 48 adaptor with death domain CREB1 1385 ... SLA2 84174 Src-like-adaptor 2 20 20q11.23 34674336 34707972 5 5 5 SOCS1 8651 suppressor of cytokine signaling 1 16 16p13.13 ... protein) alpha 12 GNAQ 2776 guanine nucleotide binding protein (G 9 9q21 79525009 79836012 32 32 32 protein), q polypeptide ...
http://www.patentsencyclopedia.com/app/20120058484
*  TATA binding蛋白TBP抗体[mAbcam 51841] -核Loading Control and ChIP Grade参考文献
Qiao H et al. The adaptor CRADD/RAIDD controls activation of endothelial cells by proinflammatory stimuli. J Biol Chem 289: ... Ge R et al. F-box protein 10, an NF-?B-dependent anti-apoptotic protein, regulates TRAIL-induced apoptosis through modulating c ... Epigenetics and Nuclear Signaling Transcription Polymerase associated factors Pol II Transcription TFIIB ... Verheyen T et al. Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits. ...
http://www.abcam.cn/tata-binding-protein-tbp-antibody-mabcam-51841-nuclear-loading-control-and-chip-grade-ab51841-references.html