Cortical spreading depression (CSD) or spreading depolarization (SD) is a wave of electrophysiological hyperactivity followed ... Neuroscientists use the term cortical spreading depression to represent at least one of the following cortical processes:[ ... "Cortical spreading depression causes and coincides with tissue hypoxia", Nat Neurosci. 29 April 2007, Takano T, Tian GF, Peng W ... "Cortical spreading depression (CSD): A neurophysiological correlate of migraine aura", Schmerz, May 17, 2008, Richter F, ...
... Am J Physiol. 1953 Apr;173(1):171-5. doi: 10.1152/ajplegacy.1953.173. ...
Different characteristics of cortical spreading depression in the sleep and wake states.. ... Different characteristics of cortical spreading depression in the sleep and wake states. ... Different characteristics of cortical spreading depression in the sleep and wake states. ... the effects of the sleep-wake cycle on neurovascular and behavioral characteristics of cortical spreading depression (CSD). ...
... Sleep Gene Linked to Migraines Posted on May 21st, 2013. by Dr. Francis Collins ... Tags: astrocytes, casein kinase I delta gene, CKIδ, cortical spreading depression, familial advanced sleep phase syndrome, ...
Dive into the research topics of Exploring the role of microglia in cortical spreading depression in neurological disease. ... Exploring the role of microglia in cortical spreading depression in neurological disease. ...
Cortical spreading depression (CSD), a wave of depolarization followed by depression of cortical activity, is a ... Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.. J Clin Invest. 2021 Sep 21: ...
... depression and stressful life events. Moreover, age, female sex and low educational status increase the risk of chronic ... Increased susceptibility to cortical spreading depression in an animal model of medication-overuse headache. Cephalalgia 34, ... Ayata, C., Jin, H., Kudo, C., Dalkara, T. & Moskowitz, M. A. Suppression of cortical spreading depression in migraine ... Vagus nerve stimulation inhibits cortical spreading depression. Pain 157, 797-805 (2016). ...
2017). Cortical spreading depression - new insights and persistent questions. DOI:. https://dx.doi.org/10.1111%2Fj.1468- ... Its believed to be caused by a wave of electrical activity that spreads across the cortex of the brain. ...
Researchers establish that vagus nerve stimulation is effective in suppressing cortical spreading depression, a trigger for ... Researchers establish that vagus nerve stimulation is effective in suppressing cortical spreading depression, a trigger for ... inhibits cortical spreading depression (CSD), which is known to be the cause of migraine aura and a trigger for headache. A ... which is caused by a slowly propagating wave of depolarization-suppression of electrical activity-spreading across the cortex. ...
Migraineurs frequently experience severe comorbidities such as allergies, depression, irritable bowel syndrome and others; many ... Migraineurs frequently experience severe comorbidities, such as allergies, depression, irritable bowel syndrome, and others; ... Charles A. Does cortical spreading depression initiate a migraine attack? Maybe not. Headache (2010) 50(4):731-3. doi:10.1111/j ... Cortical spreading depression activates and upregulates MMP-9. J Clin Invest (2004) 113(10):1447-55. doi:10.1172/JCI200421227 ...
Pietrobon, D., and Moskowitz, M. A. (2014). Chaos and commotion in the wake of cortical spreading depression and spreading ... 2010). High cortical spreading depression susceptibility and migraine-associated symptoms in Cav2.1 S218L mice. Ann. Neurol. 67 ... 2009). Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in Cav2.1 ... 2002). Multiwavelength optical intrinsic signal imaging of cortical spreading depression. J. Neurophysiol. 88, 2726-2735. doi: ...
2014) Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations. Nat Rev Neurosci 15:379- ... Cortical synchrony and information flow during transition from wakefulness to light non-rapid eye movement sleep ... This will especially be relevant for analysis of the occurrence, spatial extent, and spread of cellular signals generated ... Other work has demonstrated involvement of TRPV4 in Ca2+ influx into neurons and astrocytes during spreading depolarizations in ...
Didrik Bakke Dukefoss, Roles of Astroglia in Cortical Spreading Depression. Utgår fra Institutt for medisinske basalfag. ... Roles of Astroglia in Cortical Spreading Depression. ...
Mechanisms of initiation of cortical spreading depression There is increasing evidence from human and animal studies that ... cortical spreading depression (CSD) is the neurophysiological correlate of migraine aura and a trigger of migraine pain ... The effect of sex and estrus cycle stage on optogenetic spreading depression induced migraine-like pain phenotypes Migraine is ... Cortical spreading depolarization (CSD), the neurophysiological correlate of the migraine aura, can activate trigeminal pain ...
2014) Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations Nature Reviews ... 2013) Cortical spreading depression and migraine Nature Reviews Neurology 9:637-644. ... 2004) A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression Neuron 41:701-710. ... 2007) Cortical spreading depression releases ATP into the extracellular space and purinergic receptor activation contributes to ...
spreading cortical depression (SCD) is implicated in some migraines *high leveles of magnesium inhibit SCD *migraine patients ...
isEEG is needed to record Cortical Spreading Depression (CSD). CSD is seen in a number of pathologies of migraine, epilepsy, ... Direct Current Coupled Recordings of Cortical Spreading Depression Using Silicone Probes. Frontiers in Cell. Neuroscience, 2017 ... Figure 3. Event 2. Spread. Figure 4. Event 2. Activity becomes bi-laterally asynchronous.. Intraoperative Neurophysiological ... The patient was in no acute distress but complained of numbness, tingling, and slight weakness spreading from the feet to just ...
Patient-specific simulation of Cortical Spreading Depression. Author Julia M. Kroos Monday, 06 Jun 2022 Source location of ...
... with neurodegenerative diseases such as Alzheimers and Parkinsons diseases or psychiatric disorders such as depression and ... Effect of systemic kynurenine on cortical spreading depression and its modulation by sex hormones in rat. Exp. Neurol. 2012, ... Indeed, selective beta receptor agonists can increase the cortical endogenous level of KYNA in rat brain slices and mixed glial ... Kynurenic acid is a potential overlapped biomarker between diagnosis and treatment response for depression from metabolome ...
1992) The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischemia in the rat. J Cereb ... which is characterized by the presence of spreading depression. In ischemia, there are two types of spreading depression-like ... 1994) Cortical negative DC deflections following middle cerebral artery occlusion and KCl-induced spreading depression: effect ... It may be that forcing the use of the impaired limb results in spreading depression-like depolarizations that may lead to ...
The cortical depression stops at the central sulcus and then spreads ventrally to the meningeal trigeminal fibers, causing ... Migraine pain may in part be related to the ventral propagation of cortical spreading depression to meningeal trigeminal nerve ... The initial phase is a wave of spreading cortical depression, which is associated with suppression of spontaneous ... The cortical depression begins in the occipital region, moves anteriorly during the course of an attack, and is thought to be ...
... discuss these phenomena in the light of the neurophenomenological concepts of our body schema and cortical spreading depression ...
Migraine visual aura and cortical spreading depression-linking mathematical models to empirical evidence. L OHare, JM Asher, ...
Current thinking is that a phenomenon known as cortical spreading depression is responsible for the disorder. In cortical ... spreading depression, neurological activity is depressed over an area of the cortex of the brain. This situation results in the ... Local nerves can pinpoint the sharply-localized origin of a sting, but for pain that spreads over a larger area, the pain ... Bad attacks bring the blue-yellow zigzagging which leaves behind a bilateral central blindspot spreading over most of my visual ...
Cortical spreading depression produces long-term disruption of activity-related changes in cerebral blood volume and ... Distinct vascular conduction with cortical spreading depression J Neurophysiol. 2007 Jun; 97(6):4143-51. . View in PubMed ... Characterization of optical intrinsic signals and blood volume during cortical spreading depression Neuroreport. 2000 Jul 14; ... Biphasic direct current shift, haemoglobin desaturation and neurovascular uncoupling in cortical spreading depression Brain. ...
Cortical spreading depression has never before been accurately measured using EEGs, according to UBC electrical and computer ... "The new method opens up uses for EEGs in studying cortical spreading depression in a non-invasive manner and without a ... The low-frequency brainwave linked to migraines and epilepsy is known as cortical spreading depression (CSD) and is currently ... Non-invasive monitoring of spreading depression. Neuroscience, 2016; 333: 1 DOI: 10.1016/j.neuroscience.2016.06.056 ...
Cortical spreading depression (CSD), recognized as the neuronal phenomenon underlying visual aura, is believed to begin in the ... Partially reversible cortical metabolic dysfunction in familial hemiplegic migraine with prolonged aura. Headache. 2010 May. 50 ... occipital region and then gradually spread anteriorly. [3] This phenomenon is accompanied by a transient oligemia, followed by ...