Cortical spreading depression - Wikipedia
Cortical spreading depression (CSD) or spreading depolarization (SD) is a wave of electrophysiological hyperactivity followed ... Neuroscientists use the term cortical spreading depression to represent at least one of the following cortical processes:[ ... "Cortical spreading depression causes and coincides with tissue hypoxia", Nat Neurosci. 29 April 2007, Takano T, Tian GF, Peng W ... "Cortical spreading depression (CSD): A neurophysiological correlate of migraine aura", Schmerz, May 17, 2008, Richter F, ...
Cerebral asphyxiation and spreading cortical depression
Different characteristics of cortical spreading depression in the sleep and wake states. - International Association for the...
Different characteristics of cortical spreading depression in the sleep and wake states.. ... Different characteristics of cortical spreading depression in the sleep and wake states. ... Different characteristics of cortical spreading depression in the sleep and wake states. ... the effects of the sleep-wake cycle on neurovascular and behavioral characteristics of cortical spreading depression (CSD). ...
cortical spreading depression
Exploring the role of microglia in cortical spreading depression in neurological disease - Fingerprint - Keio University
Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model. - Munich Cluster for Systems...
Chronic migraine: risk factors, mechanisms and treatment | Nature Reviews Neurology
... depression and stressful life events. Moreover, age, female sex and low educational status increase the risk of chronic ... Increased susceptibility to cortical spreading depression in an animal model of medication-overuse headache. Cephalalgia 34, ... Ayata, C., Jin, H., Kudo, C., Dalkara, T. & Moskowitz, M. A. Suppression of cortical spreading depression in migraine ... Vagus nerve stimulation inhibits cortical spreading depression. Pain 157, 797-805 (2016). ...
Migraine Aura: Causes, Symptoms, Treatment & More
2017). Cortical spreading depression - new insights and persistent questions. DOI:. https://dx.doi.org/10.1111%2Fj.1468- ... Its believed to be caused by a wave of electrical activity that spreads across the cortex of the brain. ...
Making migraine less of a pain | Drug Discovery News
Researchers establish that vagus nerve stimulation is effective in suppressing cortical spreading depression, a trigger for ... Researchers establish that vagus nerve stimulation is effective in suppressing cortical spreading depression, a trigger for ... inhibits cortical spreading depression (CSD), which is known to be the cause of migraine aura and a trigger for headache. A ... which is caused by a slowly propagating wave of depolarization-suppression of electrical activity-spreading across the cortex. ...
Frontiers | Roads Less Traveled: Sexual Dimorphism and Mast Cell Contributions to Migraine Pathology
Migraineurs frequently experience severe comorbidities such as allergies, depression, irritable bowel syndrome and others; many ... Migraineurs frequently experience severe comorbidities, such as allergies, depression, irritable bowel syndrome, and others; ... Charles A. Does cortical spreading depression initiate a migraine attack? Maybe not. Headache (2010) 50(4):731-3. doi:10.1111/j ... Cortical spreading depression activates and upregulates MMP-9. J Clin Invest (2004) 113(10):1447-55. doi:10.1172/JCI200421227 ...
Frontiers | ATP1A2 Mutations in Migraine: Seeing through the Facets of an Ion Pump onto the Neurobiology of Disease
Pietrobon, D., and Moskowitz, M. A. (2014). Chaos and commotion in the wake of cortical spreading depression and spreading ... 2010). High cortical spreading depression susceptibility and migraine-associated symptoms in Cav2.1 S218L mice. Ann. Neurol. 67 ... 2009). Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in Cav2.1 ... 2002). Multiwavelength optical intrinsic signal imaging of cortical spreading depression. J. Neurophysiol. 88, 2726-2735. doi: ...
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2014) Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations. Nat Rev Neurosci 15:379- ... Cortical synchrony and information flow during transition from wakefulness to light non-rapid eye movement sleep ... This will especially be relevant for analysis of the occurrence, spatial extent, and spread of cellular signals generated ... Other work has demonstrated involvement of TRPV4 in Ca2+ influx into neurons and astrocytes during spreading depolarizations in ...
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The Journal of Headache and Pain | Articles
Mechanisms of initiation of cortical spreading depression There is increasing evidence from human and animal studies that ... cortical spreading depression (CSD) is the neurophysiological correlate of migraine aura and a trigger of migraine pain ... The effect of sex and estrus cycle stage on optogenetic spreading depression induced migraine-like pain phenotypes Migraine is ... Cortical spreading depolarization (CSD), the neurophysiological correlate of the migraine aura, can activate trigeminal pain ...
Real-time in vivo imaging of extracellular ATP in the brain with a hybrid-type fluorescent sensor | eLife
2014) Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations Nature Reviews ... 2013) Cortical spreading depression and migraine Nature Reviews Neurology 9:637-644. ... 2004) A Cacna1a knockin migraine mouse model with increased susceptibility to cortical spreading depression Neuron 41:701-710. ... 2007) Cortical spreading depression releases ATP into the extracellular space and purinergic receptor activation contributes to ...
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Nerve Conduction Studies
isEEG is needed to record Cortical Spreading Depression (CSD). CSD is seen in a number of pathologies of migraine, epilepsy, ... Direct Current Coupled Recordings of Cortical Spreading Depression Using Silicone Probes. Frontiers in Cell. Neuroscience, 2017 ... Figure 3. Event 2. Spread. Figure 4. Event 2. Activity becomes bi-laterally asynchronous.. Intraoperative Neurophysiological ... The patient was in no acute distress but complained of numbness, tingling, and slight weakness spreading from the feet to just ...
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Biomedicines | Free Full-Text | Memory Enhancement with Kynurenic Acid and Its Mechanisms in Neurotransmission
... with neurodegenerative diseases such as Alzheimers and Parkinsons diseases or psychiatric disorders such as depression and ... Effect of systemic kynurenine on cortical spreading depression and its modulation by sex hormones in rat. Exp. Neurol. 2012, ... Indeed, selective beta receptor agonists can increase the cortical endogenous level of KYNA in rat brain slices and mixed glial ... Kynurenic acid is a potential overlapped biomarker between diagnosis and treatment response for depression from metabolome ...
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1992) The effect of MK-801 on cortical spreading depression in the penumbral zone following focal ischemia in the rat. J Cereb ... which is characterized by the presence of spreading depression. In ischemia, there are two types of spreading depression-like ... 1994) Cortical negative DC deflections following middle cerebral artery occlusion and KCl-induced spreading depression: effect ... It may be that forcing the use of the impaired limb results in spreading depression-like depolarizations that may lead to ...
Migraine in Children: Practice Essentials, Overview, Phases of a Migraine Attack
The cortical depression stops at the central sulcus and then spreads ventrally to the meningeal trigeminal fibers, causing ... Migraine pain may in part be related to the ventral propagation of cortical spreading depression to meningeal trigeminal nerve ... The initial phase is a wave of spreading cortical depression, which is associated with suppression of spontaneous ... The cortical depression begins in the occipital region, moves anteriorly during the course of an attack, and is thought to be ...
Erowid.org: Erowid Reference 9379 : Salvia divinorum induces body awareness changes comparable to metamorphic symptoms in the...
Jordi M Asher - Google Scholar
Migraine
Current thinking is that a phenomenon known as cortical spreading depression is responsible for the disorder. In cortical ... spreading depression, neurological activity is depressed over an area of the cortex of the brain. This situation results in the ... Local nerves can pinpoint the sharply-localized origin of a sting, but for pain that spreads over a larger area, the pain ... Bad attacks bring the blue-yellow zigzagging which leaves behind a bilateral central blindspot spreading over most of my visual ...
Arthur W. Toga, PhD | Keck School of Medicine of USC
Cortical spreading depression produces long-term disruption of activity-related changes in cerebral blood volume and ... Distinct vascular conduction with cortical spreading depression J Neurophysiol. 2007 Jun; 97(6):4143-51. . View in PubMed ... Characterization of optical intrinsic signals and blood volume during cortical spreading depression Neuroreport. 2000 Jul 14; ... Biphasic direct current shift, haemoglobin desaturation and neurovascular uncoupling in cortical spreading depression Brain. ...
Scientists discover noninvasive technique to monitor migraines | ScienceDaily
Cortical spreading depression has never before been accurately measured using EEGs, according to UBC electrical and computer ... "The new method opens up uses for EEGs in studying cortical spreading depression in a non-invasive manner and without a ... The low-frequency brainwave linked to migraines and epilepsy is known as cortical spreading depression (CSD) and is currently ... Non-invasive monitoring of spreading depression. Neuroscience, 2016; 333: 1 DOI: 10.1016/j.neuroscience.2016.06.056 ...
Migraine Variants: Overview, Pathophysiology, Epidemiology
Cortical spreading depression (CSD), recognized as the neuronal phenomenon underlying visual aura, is believed to begin in the ... Partially reversible cortical metabolic dysfunction in familial hemiplegic migraine with prolonged aura. Headache. 2010 May. 50 ... occipital region and then gradually spread anteriorly. [3] This phenomenon is accompanied by a transient oligemia, followed by ...