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*  Identity of the putative serine-proteinase fold in proteins of the complement system with nine relevant crystal structures |...
C2, factor B, factor I and factor D to assess the degree of structural homology of the latter with the crystal structures. All ... Identity of the putative serine-proteinase fold in proteins of the complement system with nine relevant crystal structures. S J ... It is concluded that the double subdomain beta-sheet motif is retained in the complement sequences, but that localized ... Identity of the putative serine-proteinase fold in proteins of the complement system with nine relevant crystal structures ...
http://www.biochemj.org/content/295/1/109
*  Plus it
Complement involvement in anti-ganglioside Abs-induced axonal degeneration. The role of the complement arm of innate immunity ... comparison with C2, C4 and lysosomal enzyme release. Eur J Immunol 12:426-430, doi:10.1002/eji.1830120513, pmid:7094993. ... 2008) The role of complement and complement regulators in mediating motor nerve terminal injury in murine models of Guillain- ... 1985) Activation of the alternative pathway of complement by human peripheral nerve myelin. J Immunol 134:1810-1814, pmid: ...
http://www.jneurosci.org/content/35/17/6770
*  Patent US6664052 - Genetic polymorphism in a complement receptor - Google Patents
Complement receptors CR1 and CR2 are active in the immune response and autoimmune diseases. The susceptibility and severity of ... A method and a package for identifying single nucleotide polymorphisms in complement receptor is useful in identifying ... autoimmune disease is determined by genotyping or phenotyping an individual for complement receptor. ... C4 and C2. Deposition of these components is suggestive of the classical pathway of complement activation in this disease. ...
http://www.google.com/patents/US6664052?dq=6,073,142
*  Plus it
... other complement components defined similarly) and C5 but not C1, C4, or C2. These results suggested that activation of the ... The results are consistent with a role for the alternative pathway of complement in the inhibition of growth of rat primary ... Absorbed plasmas were depleted of the third component of complement (C3) ( ... permits activation of the alternative pathway but inhibits activation of the classical complement pathway. Sera in the presence ...
http://cancerres.aacrjournals.org/content/46/8/3886
*  ASMscience | Complement in Infections
... and discusses how acquired and inherited complement deficiencies may predispose an organism to infectious disease. Complement ... The complement activation is tightly regulated by membrane-bound and fluid-phase regulatory components to avoid runaway ... This chapter highlights the various roles of the complement system in the orchestration of the immune response towards ... Factor B, factor D, and properdin (factor P) are specific components of the alternative pathway of complement activation. ...
http://www.asmscience.org/content/book/10.1128/9781555816872.ch06
*  Complement C3-C5 Convertases - C3 Convertase Summary Report | CureHunter
Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A ... These include the different forms of C3/C5 convertases in the classical and the alternative pathways of COMPLEMENT ACTIVATION. ... 04/15/1986 - "Because EAC4bhu were lysed even by C2-deficient human serum, C3 convertase of the classical complement pathway ... Serine proteases that cleave COMPLEMENT C3 into COMPLEMENT C3A and COMPLEMENT C3B, or cleave COMPLEMENT C5 into COMPLEMENT C5A ...
http://www.curehunter.com/public/keywordSummaryD050577-Complement-C3-C5-Convertases-C3-Convertase.do
*  The assembly of early components of complement on antibody-antigen aggregates and on antibody-coated erythrocytes | Biochemical...
... was compared with the haemolytic activity and with the capacity to form the C3 convertase activity in the presence of excess C2 ... The assembly of early components of complement on antibody-antigen aggregates and on antibody-coated erythrocytes. J W F Goers ... The destruction of whole complement and of C4 activity is similar per 1,000 molecules of antibody in aggregates and cell-bound ... Radioimmune assays were developed to assay the binding of complement components C1q, C1s and C4 to antibody aggregates and to ...
http://www.biochemj.org/content/175/2/675
*  Molecular Vision: Reduction in ocular complement factor B protein in mice and monkeys by systemic administration of factor B...
... and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat Genet. 2006; 38:458-62. [PMID: ... Complement Inflamm. 1991; 8:257-60. [PMID: 1802544] * Marsh JE, Zhou W, Sacks SH. Local tissue complement synthesis--fine ... The liver has been implicated as the primary source of plasma complement factor B, and a systemic complement factor B inhibitor ... We suggest that the reduction in systemic complement activation would lead to reduced complement activation in the eye, which ...
http://www.molvis.org/molvis/v23/561/
*  Immune response Classical complement pathway
C2, C1 inhibitor, C4b, C8alpha, C6, C5AR, C5, C1r, C3aR, C3b, C8gamma, iC3b, Complement component C3 + H(,2)O = complement ... C2+H(2)O =C2a+C2b, Membrane attack complex, C1, C2b, Complement component C3b + H(,2)O = Complement component iC3b, C4BP ... component C3a + complement component C3b, H(,2)O + Complement component iC3b = Complement component C3c + complement component ... which translates the activation of the Complement component C1 complex into complement activation via cleavage of C4 and C2 to ...
http://pathwaymaps.com/maps/477/
*  anti-Complement C2 antibody [N3C3] | GeneTex
... complement component 2) for ICC/IF, WB. Anti-Complement C2 pAb (GTX105404) is tested in Human samples. 100% Ab-Assurance. ... CO2 antibody, DKFZp779M0311 antibody, C2 antibody, complement C2 antibody, complement component C2 antibody, C3/C5 convertase ... C2. 717. Q5JP69, B4DV20, P06681. 217000, 603075. NP_001269386. 56.47. Homo sapiens. C2. 717. Q5JP69, B4DV20, P06681. 217000, ... Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or ...
http://www.genetex.com/Complement-C2-antibody-N3C3-GTX105404.html
*  Anti-Complement C2 Antibody | Rabbit anti-Human Polyclonal PE | LSBio
Complement C2 antibody LS-C722609 is a PE-conjugated rabbit polyclonal antibody to human Complement C2. Validated for IHC and ... Complement C2 antibody LS-C722609 is a PE-conjugated rabbit polyclonal antibody to human Complement C2. Validated for IHC and ... Complement C2 antibody LS-C722609 is a PE-conjugated rabbit polyclonal antibody to human Complement C2. Validated for IHC and ... Complement C2 antibody was raised against recombinant C2 (Ile245-His451) expressed in E. coli. ...
https://www.lsbio.com/antibodies/complement-c2-antibody-aa245-451-pe-ihc-wb-western-ls-c722609/748039
*  Anti-Complement C2 Antibody | Rabbit anti-Human Polyclonal FITC WB | LSBio
Complement C2 antibody LS-C442556 is an FITC-conjugated rabbit polyclonal antibody to Complement C2 from human, mouse, rat and ... Complement C2 antibody LS-C442556 is an FITC-conjugated rabbit polyclonal antibody to Complement C2 from human, mouse, rat and ... Complement C2 antibody LS-C442556 is an FITC-conjugated rabbit polyclonal antibody to Complement C2 from human, mouse, rat and ... Complement C2 antibody was raised against synthetic peptide located between aa201-250 of human C2 (P06681, NP_000054). Percent ...
https://www.lsbio.com/antibodies/complement-c2-antibody-aa201-250-fitc-wb-western-ls-c442556/455262
*  Complement B/C2 (IPR011360) | InterPro | EMBL-EBI
Complement B/C2 (IPR011360). Short name: Compl_C2_B Overlapping homologous superfamilies *von Willebrand factor A-like domain ... This family contains two mammalian proteins, complement C2 and complement factor B, which, respectively, have analogous roles ... in non-mammalian species are often more or less equally related to mammalian C2 and B and may be designated as complement B/C2 ... New structural motifs on the chymotrypsin fold and their potential roles in complement factor B.. EMBO J. 19 164-73 2000 ...
http://www.ebi.ac.uk/interpro/entry/IPR011360
*  C2 Complement, Antigen, Serum - Wyoming Medical Center
Test Code C2AG C2 Complement, Antigen, Serum Reporting Name. C2 Complement, Antigen, S ... Although rare, C2 deficiency is the most common inherited complement deficiency. Homozygous C2 deficiency has an estimated ... The total complement assay (COM / Complement, Total, Serum) should be used as a screen for suspected complement deficiencies ... Low C2 levels in the presence of low C3 and C4 values are consistent with a complement-consumptive process. ...
http://wyomingmedicalcenter.testcatalog.org/show/C2AG
*  Myc-DDK-tagged ORF clone of Homo sapiens complement component 2 (C2), transcript variant 1 as transfection-ready DNA - RC208097...
C2), transcript variant 1 as transfection-ready DNA - 10 µg - OriGene - cdna clones ... Myc-DDK-tagged ORF clone of Homo sapiens complement component 2 ( ... Myc-DDK-tagged ORF clone of Homo sapiens complement component 2 ... home , products , origene , myc-ddk-tagged orf clone of homo sapiens complement component 2 (c2), transcript variant 1 as ... TrueORF Myc-DDK-tagged ORF clone of Homo sapiens complement component 2 (C2), transcript variant 1 as transfection-ready DNA ...
https://www.bioscience.co.uk/product~161365
*  C2 Gene - GeneCards | CO2 Protein | CO2 Antibody
Complement C2, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene ... GeneCards Summary for C2 Gene C2 (Complement C2) is a Protein Coding gene. Diseases associated with C2 include C2 Deficiency ... Aliases for C2 Gene Aliases for C2 Gene. * Complement C2 2 3 5 ... C2 Gene(Protein Coding) Complement C2. GCID:. GC06P031897 GIFtS ... Protein details for C2 Gene (UniProtKB/Swiss-Prot). Protein Symbol:. P06681-CO2_HUMAN. Recommended name:. Complement C2 Protein ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=C2
*  Constitutive expression and alternative splicing of the exons encoding SCRs in Sp152, the sea urchin homologue of complement...
SpBf is composed of motifs typical of the Bf/C2 protein family. Expression of Sp152 (encodes SpBf) was identified in the ... The pattern of five short consensus repeats (SCRs) in SpBf has been considered ancestral compared to other deuterostome Bf/C2 ... Comparisons between the full-length SpBf and its several splice variants with other Bf/C2 proteins suggested that the early ... Diversity of complement factor B/C2 in the common carp (Cyprinus carpio): three isotypes of B/C2-A expressed in different ...
https://www.semanticscholar.org/paper/Constitutive-expression-and-alternative-splicing-of-Terwilliger-Clow/b4b5b82733adb982033e916ff01032541bad2d79
*  SMART: CCP domain annotation
Complement C2 (P06681) (SMART). OMIM:217000: C2 deficiency. P-selectin (P16109) (SMART). OMIM:173610: Platelet alpha/delta ... Crystal Structure of Complement C3b in Complex with Factor B. 2yby. Structure of domains 6 and 7 of the mouse complement ... Structure of complement regulator Factor H mutant, T1184R.. 3rj3. Complement components factor H CCP19-20 (S1191L mutant) and ... Vaccinia Complement Protein in Complex with Heparin. 1srz. Solution structure of the second complement control protein (CCP) ...
http://smart.embl-heidelberg.de/smart/do_annotation.pl?BLAST=DUMMY&DOMAIN=CCP
*  Complement component 2 - Wikipedia
Complement C2 is a protein that in humans is encoded by the C2 gene. The protein encoded by this gene is part of the classical ... Deficiency of C2 has been associated with certain autoimmune diseases. In the classical and lectin pathways of complement ... Johnson CA, Densen P, Hurford RK, Colten HR, Wetsel RA (May 1992). "Type I human complement C2 deficiency. A 28-base pair gene ... Kam CM, McRae BJ, Harper JW, Niemann MA, Volanakis JE, Powers JC (Mar 1987). "Human complement proteins D, C2, and B. Active ...
https://en.wikipedia.org/wiki/Complement_component_2
*  Publications - London Metropolitan University
Complement C2 Receptor Inhibitor Trispanning confers an increased ability to resist complement-mediated lysis in Trypanosoma ... Dinasarapu, AR, Chandrasekhar, A, Inal, J and Subramaniam S (2013) Complement C2. UCSD Molecule Pages, 2, (2) doi:10.6072/H0.MP ... Cestari, IS, Ansa-Addo, E, Neto, L, Inal, JM and Ramirez, MI (2010) A novel mechanism to resist complement lysis and invade ... Evans-Osses, I, Ansa-Addo, E, Inal, JM and Ramirez, MI (2010) Involvement of lectin pathway activation in the complement ...
https://www.londonmet.ac.uk/research/centres/cellular-and-molecular-immunology-research-centre/publications/
*  Frontiers | DNA Sequence Analysis in Clinical Medicine, Proceeding Cautiously | Molecular Biosciences
C2/CFB Two adjacent loci that encode complement C2 and complement factor B ... proposed that complement factors play roles in maintaining the balance between activation of complement that facilitates ... Genetic variants in the complement system predisposing to age-related macular degeneration: a review. Mol. Immunol. 61, 118-125 ... Genome wide association studies revealed that variants in genes encoding complement related factors play roles in AMD. Schramm ...
https://www.frontiersin.org/articles/10.3389/fmolb.2017.00024/full
*  Case Report: Complement and infection susceptibility Diagnosis of complete deficiency of C2 - PDF
Diagnosis of complete deficiency of C2 Lennart ruedsson MD/PhD, Section of Microbiology, Immunology and Glycobiology Dept of ... Defects of the Complement System Defects of the Complement System Missing or reduced elements of the complement system, a ... Levels of complement proteins C2, C3, and C4 were within normal ranges. he serum concentration of C1q was below the detection ... Download "Case Report: Complement and infection susceptibility Diagnosis of complete deficiency of C2" ...
http://docplayer.net/24294266-Case-report-complement-and-infection-susceptibility-diagnosis-of-complete-deficiency-of-c2.html
*  Simplenlg complement Jobs, Employment | Freelancer
Search for jobs related to Simplenlg complement or hire on the world's largest freelancing marketplace with 15m+ jobs. It's ... Excel complement C # --. -- 2 Ended You need to finish developing an Excel add-on, made in C #, which consumes all the ... complement website , company complement template , sharp develop complement , convert complement , complement logo , complement ... complement work , virtuemart discount complement module , complement logos , mips complement , complement discount , download ...
https://www.freelancer.com/job-search/simplenlg-complement/
*  KEGG SSDB Paralog Search Result: mdo:100010951
mdo:100025443 complement C2 K01332 776 189 ( -) 49 0.279 262 -, mdo:100022377 protein Z, vitamin K dependent plasma gly 417 186 ... mdo:100010034 complement factor I K01333 601 410 ( -) 99 0.336 244 -, mdo:100031546 transmembrane protease, serine 13 K09643 ... mdo:107648882 complement factor B K01335 765 211 ( -) 54 0.292 233 -, mdo:103098211 probable inactive serine protease 37 417 ... mdo:100016799 complement C1r K01330 717 394 ( -) 96 0.326 261 -, mdo:103094642 chymotrypsin-like elastase family member 257 391 ...
http://www.kegg.jp/ssdb-bin/ssdb_paralog?org_gene=mdo:100010951
*  KEGG SSDB Paralog Search Result: ptr:100615529
ptr:100608992 complement C2 K01332 752 159 ( -) 42 0.254 240 -, ptr:741223 protease, serine 46 151 157 ( -) 42 0.310 113 -, ptr ... ptr:471271 complement factor I K01333 591 369 ( -) 90 0.314 236 -, ptr:451808 complement C1s K01331 688 367 ( -) 90 0.314 264 ... ptr:455533 complement factor D K01334 260 525 ( -) 126 0.374 246 -, ptr:455944 hepsin K08665 417 521 ( -) 125 0.378 249 -, ptr: ... ptr:466939 complement C1r subcomponent K01330 705 360 ( -) 88 0.315 251 -, ptr:736783 chymotrypsinogen B2-like 270 358 ( -) 87 ...
http://www.kegg.jp/ssdb-bin/ssdb_paralog?org_gene=ptr:100615529