New insights into the role of EMT in tumor immune escape - Terry - 2017 - Molecular Oncology - Wiley Online Library
Although much remains to be learned on the mechanisms at play, cancer cell clones with mesenchymal features emerging from the ... 7 Alterations of cell-cell interactions and immunological synapses. Immune killer cells, such as CTLs and NK cells, highly rely ... 2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133, 704-715. ... Cross-talks between carcinoma cells, immunosuppressive cells, and immune effector cells within the tumor microenvironment in ...
Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells -...
The empty shRNA vector contains a puromycin-resistance cassette that allowed the selection of transfected clones. On the next ... 2.1 Cell culture. HCT116 cells were a gift from B. Vogelstein (Baltimore, USA). H1299 cells with inducible p53wt or p53K120R ... J Cell Biol 93, 103-110. *32Poburski D & Thierbach R (2016) Improvement of the BALB/c-3T3 cell transformation assay: a tool for ... cells were grown in T25 cell culture flasks and DMEM containing 1 µg·mL−1 puromycin. After 6 weeks of selection, cells stably ...
Molecular cloning of newt sex pheromone precursor cDNAs: evidence for the existence of species‐specific forms of pheromones -...
A cDNA clone encoding a protein consisting of 189 amino acid residues including a s... ... Cloning of cDNA encoding a decapeptide pheromone (sodefrin) that attracts conspecific female newts was attempted. ... The plasmid containing the cDNA encoding sodefrin was used to transform a JM109 competent cell (Toyobo) and was subjected to ... A cDNA clone comparable to the sodefrin precursor clone was obtained from a cDNA library constructed from C. ensicauda ...
Elucidating tumour‐associated microglia/macrophage diversity along glioblastoma progression and under ACOD1 deficiency - Pires...
... represent the major cell type of the stromal compartment and contribute to tumour immune escape mechanisms. Thus, targeting TAM ... clone S16007D) PE and mouse anti-mouse MHC-II (clone AF6-1201) APC. Unstained (control) and stained cells were washed and re- ... 61 cells), lymphocytes (Trac+, n = 178 cells), ependymal cells (Ttr+, n = 73 cells), endothelial cells (Pecam1+, n = 328 cells ... 86 cells; TAM I: 87 cells; TAM II 159 cells. Acod1 KO, naïve: 112 cells; TAM I: 91 cells; TAM II: 298 cells) taking into ...
The VIP2 receptor: Molecular characterisation of a cDNA encoding a novel receptor for vasoactive intestinal peptide - Lutz -...
We have cloned and sequenced a cDNA (RPR4) encoding a new member of the secretin/calcitonin/parathyroid hormone (PTH) receptor ... We have cloned and sequenced a cDNA (RPR4) encoding a new member of the secretin/calcitonin/parathyroid hormone (PTH) receptor ... When RPR4 was functionally expressed in COS 7 cells, cyclic adenosine monophosphate (cAMP) production was stimulated by ... RPR4 was identified by PCR of rat pituitary cDNA, and a full-length clone was isolated from a rat olfactory bulb cDNA library. ...