Acamprosate, now under an FDA investigational new drug protocol, has been tested in clinical studies throughout Europe with ... NIAAA-sponsored clinical trials are now determining which groups of patients are most responsive to this medication and the ... The use of naltrexone which was recently approved by the FDA for the treatment of alcoholism is based on clinical and basic ... Follow-up clinical trials will include new pharmacotherapies, such as naltrexone, nalmefene, and acamprosate, combined with ...
Current Protocol. 000036-AA: Safety, Tolerability and Bioeffects of Alirocumab in Non-Treatment Seeking Heavy Drinkers ... The Section on Clinical Genomics and Experimental Therapeutics (CGET) conducts pre-clinical studies and translational clinical ... Targeting Unmet Clinical Needs in the Treatment of Alcohol Use Disorder. Lohoff FW.. Front Psychiatry. 2022 Jun 9;13:767506. ... The pre-clinical work focuses on identifying molecular mechanisms involved in addictions, utilizing a wide array of methods ...
His research spans from conceptualizing research to developing and conducting research protocols studying the neuroscience of ...
Consortium on the Neurobiology of Adolescent Drinking in Adulthood (U01 Clinical Trial Not Allowed; U24 Clinical Trial Not ... At the end of the alcohol exposure protocol, serum and liver samples were obtained for molecular characterization and ... Engineering Next-Generation Human Nervous System Microphysiological Systems (R01 Clinical Trials Not Allowed; R21 Clinical ... R43/R33 Clinical Trial Required; and R41/R42 Clinical Trial Not Allowed) RFA-NS-20-011; RFA-NS-20-010; RFA-NS-20-008; RFA-NS-20 ...
Moreover, by encouraging the use of common research metrics and protocols, as well as the sharing, aggregation, and secondary ... NIAAA will support preclinical and clinical research to generate a more thorough understanding of the fundamental mechanisms ... Such devices also have the potential to facilitate alcohol research and clinical care. ...