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*  Picalm - Phosphatidylinositol-binding clathrin assembly protein - Mus musculus (Mouse) - Picalm gene & protein
May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. ... Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction. Plays a crucial role in fetal and adult ... to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. ... Assembly protein recruiting clathrin and adapter protein complex 2 (AP2) ...
http://www.uniprot.org/uniprot/Q7M6Y3
*  Three-dimensional Analysis of Clathrin-mediated Membrane Trafficking in Living Cells | School of Physics
Clathrin-coated vesicles are the most prominent carriers of membrane traffic from cell surface to endosomes (endocytosis), a ... technological and analytical advances that I developed to directly visualize clathrin-mediated membrane traffic in three ... using these advances that defined a role for actin filament polymerization in counteracting membrane tension during clathrin- ...
http://www.physics.gatech.edu/node/4719
*  Endofin recruits clathrin to early endosomes via TOM1 | Journal of Cell Science
CB, clathrin-binding site; CB-I and CB-II: clathrin-binding enhancing sites I and II, respectively; EBD, endofin-binding domain ... Clathrin-binding assay. The clathrin-binding assay with GST fusion protein was adapted from the protocol described in a ... Optimal clathrin binding by TOM1 involves three sites: residues 300-321, 321-326 and a putative clathrin-binding box at ... The polyclonal anti-clathrin heavy chain antibody for western blotting and monoclonal anti-clathrin heavy chain for ...
http://jcs.biologists.org/content/118/3/575
*  Clathrin polymerization is not required for bulk-phase endocytosis in rat fetal fibroblasts. | JCB
Clathrin polymerization is not required for bulk-phase endocytosis in rat fetal fibroblasts.. P Cupers, A Veithen, A Kiss, P ... To assess the role of clathrin in the bulk endocytic flow of rat foetal fibroblasts, the rate of internalization of fluid-phase ... Clathrin polymerization is not required for bulk-phase endocytosis in rat fetal fibroblasts. ... The simplest explanation is that clathrin polymerization is necessary to concentrate receptor-bound ligands in primary ...
http://jcb.rupress.org/content/127/3/725
*  IJMS | Free Full-Text | Characterization of a Gene Encoding Clathrin Heavy Chain in Maize Up-Regulated by Salicylic Acid,...
In this study, the genes ZmCHC1 and ZmCHC2 encoding clathrin heavy chain in maize were cloned and characterized for the first ... a three-legged triskelion composed of three clathrin heavy chains (CHCs) and three light chains (CLCs), plays a critical role ... in clathrin-mediated endocytosis (CME) in eukaryotic cells. ... Clathrin, a three-legged triskelion composed of three clathrin ... Clathrin is a protein that plays a major role in the formation of coated vesicles. Clathrin was first isolated and named by ...
http://www.mdpi.com/1422-0067/14/7/15179/htm
*  Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D | Development
Clathrin heavy chain (Chc) co-immunopurifies with Bic-D in embryos and ovaries, and a fraction of Chc colocalizes with Bic-D. ... Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D ... Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D ... Clathrin heavy chain plays multiple roles in polarizing the Drosophila oocyte downstream of Bic-D ...
http://dev.biologists.org/content/early/2014/04/09/dev.099432
*  CiNii 論文 - Imaging of plant dynamin-related proteins and clathrin around the plasma membrane...
In animal cells, dynamin and clathrin play central roles in vesicle formation in the process of endocytosis, but the roles of ... The localization pattern and behavior of the puncta were similar to those of animal dynamin and clathrin signals reported ... Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits MERRIFIELD CJ ... Functional evidence for the identification of an Arabidopsis clathrin light chain polypeptide SCHEELE U ...
http://ci.nii.ac.jp/naid/10021912079
*  Synaptotagmin‐11 inhibits clathrin‐mediated and bulk endocytosis | EMBO Reports
Clathrin‐mediated endocytosis and bulk endocytosis are distinct modes of vesicle retrieval [1], [2], [3], [4]. Clathrin‐coated ... Syt11 inhibits clathrin‐mediated endocytosis. Clathrin‐mediated endocytosis and bulk endocytosis are both dynamin‐dependent ... Synaptotagmin‐11 inhibits clathrin‐mediated and bulk endocytosis. Changhe Wang, Yeshi Wang, Meiqin Hu, Zuying Chai, Qihui Wu, ... Chen CL, Hou WH, Liu IH, Hsiao G, Huang SS, Huang JS (2009) Inhibitors of clathrin‐dependent endocytosis enhance TGFbeta ...
http://embor.embopress.org/content/17/1/47
*  EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking. - Nuffield Department of Surgical Sciences
These biochemical and cell biological data point to a role for epsinR in AP1/clathrin budding events in the cell, just as ... clathrin, and the gamma appendage domain of the adaptor protein complex 1 (AP1). In cells, its distribution overlaps with the ... perinuclear pool of clathrin and AP1 adaptors. Overexpression disrupts the CCV-dependent trafficking of cathepsin D from the ... EpsinR is a clathrin-coated vesicle (CCV) enriched 70-kD protein that binds to phosphatidylinositol-4-phosphate, ...
https://www.nds.ox.ac.uk/publications/817530
*  anti-beta-Adaptin antibody [N3C1], Internal | GeneTex
... clathrin assembly protein complex 1 beta large chain antibody, beta1-adaptin antibody, "adaptor-related protein complex 1, beta ... where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic ...
http://www.genetex.com/beta-Adaptin-antibody-N3C1-Internal-GTX101753.html
*  The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by...
POB1 cellular colocalization with clathrin is consistent with this interaction, since Amphiphysin II is also a clathrin ligand ... The interaction of POB1 with Amphiphysin II is consistent with the co-localization of POB1 with clathrin, since Amphiphysin II ... Brett TJ, Traub LM, Fremont DH: Accessory protein recruitment motifs in clathrin-mediated endocytosis. Structure. 2002, 10 (6 ... anti-clathrin CHC (staining coated pits), anti-EEA1 (early endosomes), anti-CD63 (late endosomes), anti-GM130 (Golgi), and anti ...
https://bmcbiochem.biomedcentral.com/articles/10.1186/1471-2091-9-21
*  Publications | Bednarek Lab | Biochemistry | UW-Madison
Konopka, C. A., Backues, S. K. and Bednarek, S. Y. (2008). Dynamics of Arabidopsis Dynamin-Related Protein 1C and a Clathrin ...
https://biochem.wisc.edu/labs/bednarek/publications-bednarek-lab
*  Clathrin - Wikipedia
Clathrin is a protein that plays a major role in the formation of coated vesicles. Clathrin was first isolated and named by ... This is how clathrin gets its name, from the Latin clathratus meaning like a lattice. Coat-proteins, like clathrin, are used to ... During mitosis, clathrin binds to the spindle apparatus, in complex with two other proteins: TACC3 and ch-TOG/CKAP5. Clathrin ... Model of Clathrin assembly). *. Pérez-Gómez J, Moore I (March 2007). "Plant endocytosis: it is clathrin after all". Current ...
https://en.wikipedia.org/wiki/Clathrin
*  Clathrin | ALZFORUM
If you know of any papers that use this antibody, please contact us at antibodies [at] alzforum [dot] org for consideration in the References section.. ...
https://www.alzforum.org/antibodies/clathrin-0
*  GLUT4, Clathrin, and Glucose | Science
Thank you for your interest in spreading the word about Science.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
http://science.sciencemag.org/content/324/5931/1116.1
*  Aftiphilin, clathrin-binding box (IPR029205) | InterPro | EMBL-EBI
Aftiphilin contains a clathrin box, with two identified clathrin-binding motifs [PMID: 15811338, PMID: 15758025]. ... Aftiphilin is a component of the clathrin machinery in neurons.. FEBS Lett. 579 2177-84 2005 ...
http://www.ebi.ac.uk/interpro/entry/IPR029205
*  GLUT4, Clathrin, and Glucose | Science Signaling
Vassilopoulos et al. (see the Perspective by Orme and Bogan) now describe a function for CHC22 clathrin, a second isoform of ... A role for the CHC22 clathrin heavy-chain isoform in human glucose metabolism. Science 324, 1192-1196 (2009). [Abstract] [Full ... clathrin that is present in humans and not in mice. CHC22 participates in the biogenesis of the intracellular compartment that ...
https://stke.sciencemag.org/content/2/73/ec185
*  Addgene: Clathrin-LCa-ECFP
Xiaowei Zhuang's lab contains the insert Clathrin, light polypeptide (LCa) and is published in Proc Natl Acad Sci U S A. 2008 ... Epsin 1 is a cargo-specific adaptor for the clathrin-mediated endocytosis of the influenza virus. Chen C, Zhuang X. Proc Natl ... Clathrin-LCa-ECFP was a gift from Xiaowei Zhuang (Addgene plasmid # 21742 ; http://n2t.net/addgene:21742 ; RRID:Addgene_21742) ...
https://www.addgene.org/21742/
*  Clathrin adaptor protein - Wikipedia
Clathrin coats contain both clathrin (acts as a scaffold) and adaptor complexes that link clathrin to receptors in coated ... Clathrin adaptor proteins, also known as adaptins, are vesicular transport adaptor proteins associated with clathrin. These ... Adaptins recognise and bind to clathrin through their hinge region (clathrin box), and recruit accessory proteins that modulate ... One function of clathrin and AP2 complex-mediated endocytosis is to regulate the number of GABA(A) receptors available at the ...
https://en.wikipedia.org/wiki/Clathrin_adaptor_protein
*  Sharing Responsibility for Clathrin Coat Assembly
They found that clathrin takes over from adaptors as a hub as clathrin assembles into a coat. This shift requires collaboration ... Sharing Responsibility for Clathrin Coat Assembly. Aug 16, 2006 - 8:58:00 AM, Reviewed by: Dr. Priya Saxena. ... Clathrin coat formation, Schmid et al. propose, is an outgrowth of increasingly stable interactions among a shifting network of ... Clathrin molecules three-pronged pinwheel-shaped proteins form an elaborate lattice coat around the vesicles, which ultimately ...
http://www.rxpgnews.com/cytology/Sharing_Responsibility_for_Clathrin_Coat_Assembly_4848/4848.shtml
*  Huntingtin-interacting protein 1, clathrin-binding domain (IPR032422) | InterPro | EMBL-EBI
This binding then stimulates clathrin lattice assembly. HIP1 is an obligate binding partner for Huntingtin, and loss of this ... Huntingtin-interacting protein 1, clathrin-binding domain (IPR032422). Short name: HIP1_clath-bd ... Clathrin light-chain binds to a flexible coiled-coil domain in HIP1 and induces a compact state that is refractory to actin ... It carries a highly conserved HADLLRKN sequence motif at its N terminus which effects the binding of HIP1R to clathrin light- ...
http://www.ebi.ac.uk/interpro/entry/IPR032422
*  'clathrin coated vesicles' Protocols and Video...
Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy', ' ... In vivo and in vitro Studies of Adaptor-clathrin Interaction', 'Models and Methods to Evaluate Transport of Drug Delivery ... Video articles in JoVE about clathrin coated vesicles include 'Applications of pHluorin for Quantitative, Kinetic and High- ... In vivo and in vitro Studies of Adaptor-clathrin Interaction. Daniel Feliciano1, Jarred J. Bultema1, Andrea L. Ambrosio1, ...
https://www.jove.com/keyword/clathrin+coated+vesicles
*  SMART: Pfam domain Clathrin
Clathrin. PFAM accession number:. PF00637. Interpro abstract (IPR000547):. Clathrin is a triskelion-shaped cytoplasmic protein ... or perform clathrin-like functions. CHCR repeats in the clathrin heavy chain, Saccharomyces cerevisiae Vamp2 and human Vamp6 ... Clathrin functions as a trimer, and these trimers, or triskelions, are comprised of three legs joined by a central vertex. Each ... The clathrin heavy-chain contains a 145-residue repeat that is present in seven copies [(PUBMED:10360576), (PUBMED:17702618)]. ...
http://smart.embl.de/smart/do_annotation.pl?DOMAIN=Pfam:Clathrin&START=410&END=536&E_VALUE=3.9e-9&TYPE=PFAM&BLAST=TQKRSQLVKKLNDSDHQSSTSPLMEGTPTIKSKKKLLQIIDTTLLKCYLHTNVALVAPLLRLENNHCHIEESEHVLKKAHKYSELIILYEKKGLHEKALQVLVDQSKKANSPLKGHERTVQYLQHLG
*  clathrin, Heavy Chain (Hc) (CLTC) Antibodies
clathrin heavy chain , Clathrin Heavy Chain family member (chc-1) , clathrin heavy chain 1 , clathrin heavy-chain , clathrin, ... clathrin, heavy chain (Hc) , clathrin, heavy polypeptide a , clathrin, heavy polypeptide a (Hc) , clathrin, heavy chain (Hc) L ... Loss of SNX-1, RME-8, or the clathrin chaperone Hsc70/HSP-1 leads to over-accumulation of endosomal clathrin, reduced clathrin ... clathrin, Heavy Chain (Hc) (CLTC) Antigen Profile Protein Summary Clathrin is a major protein component of the cytoplasmic face ...
https://www.antibodies-online.com/abstract/clathrin%2C+Heavy+Chain+
*  Picalm phosphatidylinositol binding clathrin assembly protein [Mus musculus (house mouse)] - Gene - NCBI
Cargo recognition for clathrin-mediated endocytosis, organism-specific biosystem (from REACTOME) Cargo recognition for clathrin ... Clathrin derived vesicle budding, organism-specific biosystem (from REACTOME) Clathrin derived vesicle budding, organism- ... Clathrin-mediated endocytosis, organism-specific biosystem (from REACTOME) Clathrin-mediated endocytosis, organism-specific ... Picalm phosphatidylinositol binding clathrin assembly protein [Mus musculus] Picalm phosphatidylinositol binding clathrin ...
https://www.ncbi.nlm.nih.gov/gene/?term=233489