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*  Circadian clocks and pregnancy | Frontiers Research Topic
ClockΔ19) had prolonged and non-productive parturition, suggestive of a role for circadian clocks in the parturition event. ... A key study to draw attention to the potential role of the circadian clock and pregnancy was that of Miller et al (2004), who ... A growing body of research reveals circadian clock gene expression in the uterus of non-pregnant and pregnant mammals. ... 2010) examined expression of circadian clock genes in the mouse uterus in late pregnancy and found significant daily mRNA ...
https://www.frontiersin.org/research-topics/1010/circadian-clocks-and-pregnancy
*  Abstract 275: The Intrinsic Circadian Clock within the Cardiomyocyte Regulates Myocardial Efficiency and Mitochondrial Function...
To test the hypothesis that the circadian clock directly influences myocardial metabolism, a cardiomyocyte-specific circadian ... Recent studies suggest that the transcriptional co-activator, PGC1α, is an integral component of the mammalian circadian clock ... In conclusion, we report that disruption of the circadian clock within the cardiomyocyte decreases mitochondrial biogenesis and ... Abstract 275: The Intrinsic Circadian Clock within the Cardiomyocyte Regulates Myocardial Efficiency and Mitochondrial Function ...
http://circ.ahajournals.org/content/116/Suppl_16/II_35.2
*  Manipulating Plants' Circadian Clock May Make All-Season Crops Possible | THCFarmer Community
Circadian Clock May Make All-Season Crops Possible http://www.sciencedaily.com/releases/2011/09/110901134643.htm... ... Manipulating Plants' Circadian Clock May Make All-Season Crops Possible Discussion in 'General Gardening' started by ... The circadian clock is the internal timekeeper found in almost all organisms that helps synchronize biological processes with ... In plants, this clock is crucial for adjusting growth to both time and day and to the seasons.. The clock operates through the ...
https://www.thcfarmer.com/community/threads/manipulating-plants-circadian-clock-may-make-all-season-crops-possible.39757/
*  IDEALS @ Illinois: The Role of Atypical PKC in the Plasticity of the Circadian Clock in the Rat Suprachiasmatic Nucleus
Light/GLU pulses can reset the mammalian circadian clock at specific times: in the early night, light/GLU delays clock phase, ... The Role of Atypical PKC in the Plasticity of the Circadian Clock in the Rat Suprachiasmatic Nucleus. Welcome to the IDEALS ... The Role of Atypical PKC in the Plasticity of the Circadian Clock in the Rat Suprachiasmatic Nucleus. Huang, Sufang ... In mammals, the daily rhythms of biological functions are generated by the master circadian clock, which locates within the ...
https://www.ideals.illinois.edu/handle/2142/86316
*  Circadian Medicine | Neuroscience | Life Sciences | Subjects | Wiley
4.4 Reciprocity: sleep-wake feedback to the circadian clock 69. 4.5 Conclusions: Circadian clocks and sleep are intertwined ... Part II Circadian Regulation of Major Physiological Systems 95. 6 Physiology of the Adrenal and Liver Circadian Clocks 97. ... 2 Molecular Determinants of Human Circadian Clocks 25. Steven A. Brown. 2.1 Molecular elements of human clocks: a brief review ... 8.5 The circadian clock and vascular cell signaling 122. 8.6 The circadian rhythm in blood pressure, nighttime hypertension, ...
https://www.wiley.com/en-us/Circadian+Medicine-p-9781118467831
*  Charles Weitz | Department of Neurobiology
Mammalian Circadian Clocks. Circadian clocks are molecular oscillators with ~24-hour periods that drive daily biological ... In mammals, circadian clocks are present in most if not all cells. These distributed clocks control a myriad of processes, in ... 1. Class-average electron microscopy images of the mouse nuclear PER complex, a core circadian clock machine. It is a 1.9-MDa ... The focus of our efforts at present is to understand the circadian clock in terms of the integrated functions of its several ...
http://neuro.hms.harvard.edu/people/faculty/charles-weitz
*  Deletion of Rictor in Brain and Fat Alters Peripheral Clock Gene Expression and Increases Blood PressureNovelty and...
Clock genes are part of a hierarchically organized circadian clock system in which the suprachiasmatic nucleus (SCN) in the ... The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu Rev Physiol. 2010; ... Pressed for time: the circadian clock and hypertension. J Appl Physiol (1985). 2009;107:1328-1338. doi: 10.1152/japplphysiol. ... Integration of metabolic and cardiovascular diurnal rhythms by circadian clock. Endocr J. 2012;59:447-456. ...
http://hyper.ahajournals.org/content/66/2/332
*  Yong Zhang, Role of DOMINO in regulation of circadian rhythms | University of Nevada, Reno
The role of DOMINO in regulation of circadian rhythms in Drosophila. Most organisms on earth use circadian clocks to modulate ... Malfunctions of circadian clocks are correlated with many human diseases. For example, disrupted circadian rhythms in shift ... reveal a novel mechanism of the circadian clock by chromatin remodeling and will advance our understanding of circadian clocks ... and the molecular mechanisms of circadian clocks were, in great part, discovered in Drosophila. Studying circadian rhythms in ...
https://www.unr.edu/neuroscience/center/projects/zhang-role-of-domino-in-circadian-regulation
*  KEGG PATHWAY: Circadian rhythm - Macaca mulatta (rhesus monkey)
Circadian rhythm is an internal biological clock, which enables to sustain an approximately 24-hour rhythm in the absence of ... In mammals, the circadian clock mechanism consists of cell-autonomous transcription-translation feedback loops that drive ... Circadian rhythm - Macaca mulatta (rhesus monkey) [ Pathway menu , Organism menu , Pathway entry , Download KGML , Show ... The second loop is a positive feedback loop driven by the CLOCK/BMAL1 heterodimer, which initiates transcription of target ...
http://www.genome.jp/kegg-bin/show_pathway?mcc04710
*  Circadian Waves of Expression of the APRR1/TOC1 Family of Pseudo-Response Regulators in Arabidopsis thaliana: Insight into the...
TOC1 is believed to be a component of the presumed circadian clock (or central oscillator). Based on these facts, in this study ... TOC1 is believed to be a component of the presumed circadian clock (or central oscillator). Based on these facts, in this study ... propose that the circadian waves of the APRR1/TOC1 family members are most likely a molecular basis of such a biological clock ... of the APRR1/TOC1 family are together all involved in an as yet unknown mechanism underlying the Arabidopsis circadian clock. ...
http://oxfordindex.oup.com/view/10.1093/pcp/pcd043
*  Circadian rhythms in gene transcription imparted by chromosome...
Circadian rhythms in gene transcription imparted by chromosome compaction in the cyanobacterium Synechococcus elongatus: In the ... This chromosome compaction rhythm is both circadian clock-controlled and kai-dependent. Although sasA is required for global ... We demonstrate that the circadian clock also regulates a chromosome compaction rhythm. ... and C and the sasA gene encode the functional protein core of the timing mechanism essential for circadian clock regulation of ...
https://www.mysciencework.com/publication/show/circadian-rhythms-in-gene-transcription-imparted-by-chromosome-compaction-in-the-cyanobacterium-synechococcus-elongatus
*  Circadian rhythm - Wikipedia
DeBruyne (2006). "A Clock Shock: Mouse CLOCK Is Not Required for Circadian Oscillator Function". Neuron. 50 (3): 465-77. doi: ... The simplest known circadian clocks are bacterial circadian rhythms, exemplified by the prokaryote cyanobacteria. Recent ... Biological clock in mammals[edit]. A variation of an eskinogram illustrating the influence of light and darkness on circadian ... Joseph Takahashi discovered the first mammalian circadian clock mutation (clockΔ19) using mice in 1994.[12][13] However, recent ...
https://en.bywiki.com/wiki/Circadian_rhythm
*  Circadian clock - Wikipedia
Variation in circadian clocks[edit]. While a precise 24-hour circadian clock is found in many organisms, it is not universal. ... Plant clocks[edit]. The circadian clock in plants has completely different components to those in the animal, fungus or ... A circadian clock, or circadian oscillator, is a biochemical oscillator that cycles with a stable phase and is synchronized ... Mammalian clocks[edit]. Selective gene knockdown of known components of the human circadian clock demonstrates both active ...
https://en.wikipedia.org/wiki/Circadian_clock
*  Resonating circadian clocks enhance fitness in cyanobacteria | PNAS
However, FRP or clock-null mutations of circadian clock genes in Drosophila (per) or Neurospora (frq) do not obviously impair ... The Circadian Clock in Arabidopsis Roots Is a Simplified Slave Version of the Clock in Shoots ... The circadian clock controls the expression pattern of the circadian input photoreceptor, phytochrome B ... Quinone sensing by the circadian input kinase of the cyanobacterial circadian clock ...
https://www.pnas.org/content/95/15/8660
*  Circadian clocks: Providing Feedback | Science Signaling
Further clues into the regulation of circadian clocks are the subject of two reports. In plants and insects, cryptochromes ( ... In Drosophila, three of the critical clock genes, period (per), timeless (tim), and Drosophila Clock (dClk), are expressed ... role of CRY1 and light-independent role of CRY1 and light-iIndependent role of CRY1 and CRY2 in the mammalian circadian clock. ... show that CRY1 and CRY2 play a central role in the mammal clock, but in a light-independent fashion--they appear to regulate ...
http://stke.sciencemag.org/content/1999/5/tw7
*  Circadian clock not essential
... 25.09.2015. A circadian clock is not mandatory for living beings to adapt their activities to a ... The circadian clock sets the pace. Nevertheless, clockless fruit flies do show some behavioural differences. The clock seems to ... But this view of circadian clocks as central mechanisms that drive circadian rhythms was recently challenged. Scientists had ... And ideally its circadian clock will make the animal stop its activities before it is dark the next day. ...
http://www.innovations-report.com/html/reports/life-sciences/circadian-clock-not-essential.html
*  How Our Circadian Clocks Regulate Energy Metabolism
... body clocks) present in different parts of the body determine when and how much energy must be supplied by mitochondria (the ... Circadian Rhythm may Help Regulate Inflammatory Diseases. Controlling of the circadian rhythm or biological clock may help ... Relationship between circadian clock and energy production The scientists also showed that the mitochondrial network loses its ... Study Identifies How Internal Circadian Clocks Encode External Daily Rhythms of Excitability. A mechanism through which ...
https://www.medindia.net/news/how-our-circadian-clocks-regulate-energy-metabolism-177702-1.htm
*  Molecular and Genetic Analysis of Mammalian Circadian Clocks | HHMI.org
The molecular mechanisms of the clock are being studied at the biochemical and genomic levels. ... Joseph Takahashi is interested in understanding the genetic and molecular basis of circadian rhythms as well as other complex ... The Clock mutation lengthens circadian period by 4 hours in homozygous mutants, followed by a complete loss of circadian ... Molecular Mechanism of the Clock. The circadian clock in mammals is composed of an autoregulatory transcriptional network with ...
https://www.hhmi.org/research/molecular-and-genetic-analysis-mammalian-circadian-clocks
*  Light and the Human Circadian Clock | SpringerLink
Most clocks use the light-dark cycle as environmental signal (zeitgeber) for this active synchronisation. How we... ... The circadian clock can only reliably fulfil its function if it is stably entrained. ... Light and the Human Circadian Clock. In: Kramer A., Merrow M. (eds) Circadian Clocks. Handbook of Experimental Pharmacology, ... The circadian clock can only reliably fulfil its function if it is stably entrained. Most clocks use the light-dark cycle as ...
https://link.springer.com/chapter/10.1007%2F978-3-642-25950-0_13
*  Circadian clock cryptochrome proteins regulate autoimmunity | PNAS
Circadian clock cryptochrome proteins regulate autoimmunity. Qi Cao, Xuan Zhao, Jingwen Bai, Sigal Gery, Haibo Sun, De-Chen Lin ... C1qa, C1qb, C1qc, C6, Fcgr3, and Fcgr4 were down-regulated, and circadian clock genes Per2, Per3, Nr1d1, and Nr1d2 were up- ... 2012) Circadian expression of clock genes in mouse macrophages, dendritic cells, and B cells. Brain Behav Immun 26:407-413. ... indicating that the intrinsic circadian clock regulates inflammatory innate immune functions (11). The circadian oscillations ...
https://www.pnas.org/content/114/47/12548.long
*  Unnatural light-dark cycles expose duelling circadian clocks
One clock followed the artificially short 11-hr. day/11-hr. night schedule, while the other followed a longer cycle (>24 hrs ... In mammals, the endogenous daily pacemaker that regulates circadian rhythms like sleep and wakefulness is localized to a ... a regimen that effectively pushes the limits of the SCN s ability to set the clock to day length - researchers have discovered ... that underlies the workings of the circadian timing system. In humans, some of the symptoms arising from jet lag or rotating ...
https://www.innovations-report.com/html/reports/life-sciences/report-28753.html
*  'circadian clocks' Protocols and Video...
... circadian clocks' include 'Single-cell Resolution Fluorescence Live Imaging of Drosophila Circadian Clocks in Larval Brain ... Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters', 'In Vitro ... Rapid Analysis of Circadian Phenotypes in Arabidopsis Protoplasts Transfected with a Luminescent Clock Reporter', 'A ... Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures', ' ...
https://www.jove.com/keyword/circadian+clocks
*  Disruptions In Circadian Clock Have Health Consequences - Redorbit
... in the brain has a master circadian clock that manages cells, many of which have their own molecular clocks. ... According to the Cleveland Clinic, the circadian rhythm, otherwise known as the "internal body clock," manages the body´s 24- ... This study is the first to definitively prove that the body´s circadian biological clock controls insulin activity. ... The researchers used different approaches to disrupt the circadian clocks of individual mice. Measurements were taken at ...
https://www.redorbit.com/news/health/1112789435/fighting-your-biological-clock-can-have-health-consequences-022213
*  Dartmouth researchers find two circadian clocks in the same plant tissue
Dartmouth researchers have found evidence of two circadian clocks working within the same tissue of the plant Arabidopsis ... McClung and his students continued the study by examining how the circadian clocks were reset by different stimuli. For example ... Dartmouth researchers have found evidence of two circadian clocks working within the same tissue of the plant Arabidopsis ... Having two clocks with different sensitivities to light and to temperature is a better way to ensure that both signals of ...
http://www.dartmouth.edu/~news/releases/2003/may/050703.html
*  Circadian Clock Times Immune Response | Medpage Today
... to pathogenic invasion is controlled by circadian rhythms, researchers found. ... Circadian Clock Times Immune Response. The molecular response of an organism -- be it mouse or man -- to pathogenic invasion is ... To examine the influence of the circadian clock on immunity at the molecular level, Fikrig's group conducted a series of murine ... Source Reference: Silver A, et al "The circadian clock controls tool-like receptor 9-mediated innate and adaptive immunity" ...
https://www.medpagetoday.com/infectiousdisease/vaccines/31235