The hydrolyzed chylomicrons are now called chylomicron remnants. The chylomicron remnants continue circulating the bloodstream ... This interaction causes the endocytosis of the chylomicron remnants, which are subsequently hydrolyzed within lysosomes. ... The chylomicron at this stage is then considered mature. Via apolipoprotein C-II, mature chylomicrons activate lipoprotein ... The hydrolyzed VLDL particles are now called VLDL remnants or intermediate-density lipoproteins (IDLs). VLDL remnants can ...

Influence of chylomicron remnants on human monocyte activation in vitro. Nutr Metab Cardiovasc Dis. 21(11):871-8. PMID: ... Suppression of nuclear factor-B activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of ... Chylomicron remnants: mediators of endothelial dysfunction? Biochem Soc Trans 35:442-5. PMID:17511623 ... Inhibition of macrophage inflammatory cytokine secretion by chylomicron remnants is dependent on their uptake by the low ...

"Chylomicrons" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH (Medical Subject ... Intestinal scavenger receptor class B type I as a novel regulator of chylomicron production in healthy and diet-induced obese ... This graph shows the total number of publications written about "Chylomicrons" by people in Harvard Catalyst Profiles by year, ... Below are the most recent publications written about "Chylomicrons" by people in Profiles. ...

In the fasting state, chylomicrons and chylomicron remnants are not normally detected in plasma. ... When the chylomicrons are reduced in TG content, they become remnants that are rapidly cleared by the liver (apoprotein E binds ... Chylomicrons, which are TG rich, enter the lymphatic system. The thoracic duct empties into the vena cava, and chylomicrons ... Apoprotein B-48 is a chylomicron structural protein. Chylomicrons bind to LPL via apoprotein C-II. Once acted on by LPL, which ...

To investigate the role of apoE in hepatic uptake of chylomicron remnants, we studied chylomicron metabolism in transgenic mice ... Data from experiments with very low density lipoprotein and LDL showed that this system is specific for chylomicron remnants. ... Polyacrylamide gel analysis of chylomicrons and remnants that had been reisolated from plasma and from liver membrane after the ... These results provide strong evidence for the secretion-recapture process of apoE, whereby chylomicron remnants enter the ...

Why are they called remnants?. They are remnants of triglyceride-rich lipoproteins. There are two types of triglyceride-rich ... One type is very large particles called chylomicrons that come from the gut following a meal. The other type is very low- ... and then they are called remnants. These remnants can be cleared by the liver, or they can accumulate in the artery wall and ... How those remnants are related to inflammation and changes in immune cells is another area that were very actively studying ...

Regulation of apoB-100 and chylomicron remnant metabolism with statin and fish oil on obesity. Watts, G., Redgrave, T., Mori, T ... Does pravastatin increase chylomicron remnant catabolism in postmenopausal women with type 2 diabetes mellitus?. Ng, T. W., ... Application of a new breath test to study chylomicron remnant metabolism in familial hypercholesterolaemia. Redgrave, T., Watts ...

10 Type III HLP results from the accumulation of chylomicron remnants from intestinal lipoproteins and VLDL remnants derived ... APOE is an integral component of chylomicrons, VLDL, and HDL in the peripheral system (Table 1). It operates as part of an ... APOE is also involved in the formation of chylomicrons and VLDL and affects the activity of other lipid metabolism-associated ... and chylomicrons). APOE ε2 was studied in disorders associated with elevated cholesterol levels or lipid derangements such as ...

... chylomicrons and remnant lipoproteins; and APOC3, which slows the clearance of triglyceride-rich lipoproteins and their remnant ...

The newly synthesized TG and CE in the chylomicrons are hydrolyzed by lipoprotein lipase (LPL) to yield chylomicron remnant ... In indirect reverse cholesterol transport, CE is exchanged 1 : 1 for TG between apo B-containing lipoproteins (chylomicrons, ... and then absorbed by intestinal mucosal cells and secreted into mesenteric lymphatic vessels in the form of chylomicrons with ...

... increase chylomicron and chylomicron remnant apoE and ApoCIII content (both of which inhibit lipoprotein lipase, thereby ... and to have higher levels of chylomicrons and chylomicron remnants, which are also cleared more slowly (Bergeron 1995; ... saturated fats provoke twice the chylomicron triglyceride response and several-fold greater VLDL response." ...

... increase chylomicron and chylomicron remnant apoE and ApoCIII content (both of which inhibit lipoprotein lipase, thereby ... and to have higher levels of chylomicrons and chylomicron remnants, which are also cleared more slowly (Bergeron 1995; ... saturated fats provoke twice the chylomicron triglyceride response and several-fold greater VLDL response." ...

Its interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step ...

Chylomicron and chylomicron remnant metabolism in STZ-induced diabetic rats. Diabetes. 1992 Mar; 41(3):325-33. Staprans I, Pan ... Exposure to cigarette smoke delays the plasma clearance of chylomicrons and chylomicron remnants in rats. Am J Physiol. 1997 ... Chylomicrons can inhibit endotoxin activity in vitro. J Surg Res. 1991 Nov; 51(5):413-6. Eichbaum EB, Harris HW, Kane JP, Rapp ... Chylomicrons enhance endotoxin excretion in bile. Infect Immun. 1993 Aug; 61(8):3496-502. Read TE, Harris HW, Grunfeld C, ...

oil chylomicron remnants and HDL for hepatic lipase [56]. Thus, olive oil could prevent HDL-c postprandial decrease, ...

Apo B-450 is associated with chylomicrons and their remnants, and apo B-100 is associated with low-density lipoprotein (LDL), ...

Chylomicron Remnants MeSH Plaque, Atherosclerotic MeSH DeCS ID:. 50504 Unique ID:. D050197 ...

A knowledge graph of biological entities such as genes, gene functions, diseases, phenotypes and chemicals. Embeddings are generated with Walking RDF and OWL method ...

Chylomicron remnants, VLDL, IDL, LDL, and Lp (a) are all pro-atherogenic while HDL is anti-atherogenic. ...

Macrophages, hepatocytes, and fibroblasts, intake lipid-deficient polyproteins, remnants of HDL, and chylomicrons into cell, ...

... role of retinol-binding protein and chylomicron remnants. J Nutr Biochem, 10 (6), 345-52. DOI 10.1016/s0955-2863(99)00013-3, ...

Transport cholesterol to the liver in the form of triglyceride-depleted chylomicron remnants ... The lipoproteins in order of increasing triglycerides are HDL, LDL, IDL, VLDL, and chylomicrons. ... Hydrolyzes triglycerides circulating in chylomicrons and VLDLs into fatty acids and glycerine, which can be taken up by cells [ ... Absorbed lipids are transported in chylomicrons via the lymphatic system into the bloodstream, where they reach the liver, ...

... exercise may reduce the number of chylomicrons and chylomicron remnants and improve exogenous lipoprotein metabolism. ... The values of apoB48, a marker of the chylomicron particle number, at 2, 4, and 6 h after the fat intake and IAUC for apoB48 ... remnant-like particle-TG (RLP-TG), lactate, free fatty acid (FFA), insulin, and glucose.. Results: In both experiments, ...

Chylomicrons are rich in triglyceride and secreted by the intestine postprandially. Chylomicrons compete with VLDL for ... there is a large increase in chylomicron and very low-density lipoprotein (VLDL) concentrations. The accumulation of ... Chylomicrons are rich in triglyceride and secreted by the intestine postprandially. Chylomicrons compete with VLDL for ... Blood Coagulation, Cholesterol Esters, Cholesterol, Dietary, Chylomicrons, Coronary Disease, Humans, Hyperlipidemias, Insulin ...

This inverse relationship results from the fact that vitamin K in plasma is bound to chylomicrons and chylomicron remnants, ... Clearance of chylomicrons and their remnants from the circulation depends on ApoEs binding to a hepatic receptor, and the rate ... are modified into smaller chylomicron remnants, and rapidly shunted to the liver - vitamin K is efficiently extracted and used ... After its absorption in the small intestine, where all vitamin K is incorporated into chylomicrons - which form in the small ...

Reaction Name: chylomicron remnant:apoE complex + LDLR =, chylomicron remnant:apoE:LDLR complex See in Reactome ... Reaction Name: chylomicron =, TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols See in Reactome ... Reaction Name: chylomicron =, TG-depleted chylomicron + 50 long-chain fatty acids + 50 diacylglycerols See in Reactome ... Reactome Name: Chylomicron clearance See in Reactome R-HSA-174824 R-HSA-174824. Reactome Name: Plasma lipoprotein assembly, ...

... chylomicrons into fat and muscle cells; only chylomicron remnants are taken up by the liver. ... this phase is to take up remnants of chylomicrons, sort out the complex mix of lipids contained (e. g., lipid-soluble vitamins ... Within the cell, lipids are reassembled, combined to chylomicrons and set free at the basolateral side of the enterocytes. From ... From there, enterocyte-produced chylomicrons enter the blood stream via thoracic duct and venous angle. Lipoprotein lipase (LPL ...

LDL, VLDL, Lp(a), chylomicron remnant particles, and IDL. And as such, what this table shows is that replacement of PUFAs with ...

As triglycerides are removed from the chylomicrons, they become smaller. These chylomicron remnants travel to the liver, where ... The contents of chylomicron remnants, as well as other lipids in the liver, are incorporated into another type of lipoprotein ... Chylomicrons Deliver Lipids to Cells for Utilization and Storage. On the previous page, we learned that chylomicrons are formed ... The job of chylomicrons is to deliver triglycerides (originating from digested food) to the cells of the body, where they can ...