Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model. - Department of Physiology,...
... that express wild-type α-synuclein from the complete human SNCA locus at disease-relevant levels and display a transgene ... we generated bacterial artificial chromosome transgenic mice (SNCA-OVX) ... Chromosomes, Artificial, Bacterial, Corpus Striatum, Dopaminergic Neurons, Humans, Mice, Parkinsonian Disorders, Substantia ... we generated bacterial artificial chromosome transgenic mice (SNCA-OVX) that express wild-type α-synuclein from the complete ...