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*  Selective Chromatid Segregation Mechanism Explains the Etiology of Chromosome 11 Translocation-Associated Psychotic Disorders:...
Selective Chromatid Segregation Mechanism Explains the Etiology of Chromosome 11 Translocation-Associated Psychotic Disorders: ... The paradoxes we try to resolve here concern the fact that the translocation breakpoints for chromosome 11 lie far apart, ... Gene Regulation and Chromosome Biology Laboratory. National Cancer Institute, Center for Cancer Research. National Institutes ... Gene Regulation and Chromosome Biology Laboratory, National Cancer Institute, Center for Cancer Research, National Institutes ...
https://www.omicsonline.org/peer-reviewed/selective-chromatid-segregation-mechanism-explains-the-etiology-of-chromosome-11-translocationassociated-psychotic-disorders-a-rev-28534.html
*  The Inherited Diseases Group | Laboratóriumi Medicina Intézet
In cases with structural chromosome aberrations the identification of precise breakpoints and involved genes using microarray ... Partial and total microdeletions of the AZF region on chromosome Y are detected by sequence tagged site (STS) analysis. ... Presence of harmless small supernumerary marker chromosomes hampers molecular genetic diagnosis: a case report. Mol Med Rep. ...
http://lmi.med.unideb.hu/hu/15/04/17/inherited-diseases-group
*  KAKEN - Research Projects | Molecular analysis of chromosome breakpoints in human chromosome 1 specific for malignant lymphoma ...
Molecular analysis of chromosome breakpoints in human chromosome 1 specific for malignant lymphoma. Research Project ... both of which contained marker chromosomes consisted with an insertional chromosome fragment derived from chromosome 1. ... As a result, all of the five cell lines had different breakpoints. The breakpoint of HMS, an in vivo cell line maintained in ... Narrowing the possible breakpoint is still on going.. On the other hand, we have established two independent cell lines from ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13670206/
*  A Chromosome Breakpoint Mapping Strategy to Identify Candidate Genes for Nonsyndromic X-linked Mental Retardation within Xp11.2...
A Chromosome Breakpoint Mapping Strategy to Identify Candidate Genes for Nonsyndromic X-linked Mental Retardation within Xp11.2 ... A Chromosome Breakpoint Mapping Strategy to Identify Candidate Genes for Nonsyndromic X-linked Mental Retardation within Xp11.2 ... A Chromosome Breakpoint Mapping Strategy to Identify Candidate Genes for Nonsyndromic X-linked Mental Retardation within Xp11.2 ... A Chromosome Breakpoint Mapping Strategy to Identify Candidate Genes for Nonsyndromic X-linked Mental Retardation within Xp11.2 ...
http://www.clinsci.org/content/104/s49/39P.3
*  Ring chromosomes, breakpoint clusters, and neocentromeres in sarcomas.
... Macchia, Gemma; Hansén Nord, Karolin LU ; Zoli, Monica ... We found nine breakpoint cluster regions potentially involved in the genesis of RGM chromosomes,... (More). Gene amplification ... We found nine breakpoint cluster regions potentially involved in the genesis of RGM chromosomes, which turned out to be ... We found nine breakpoint cluster regions potentially involved in the genesis of RGM chromosomes, which turned out to be ...
https://lup.lub.lu.se/search/publication/301e11f0-736a-4781-a5b4-929c72a80017
*  Day 356 (22q11.1-22q11.23): the Philadelphia chromosome breakpoint | Genome Year
BCR is well known because it becomes pasted onto Chromosome 9 in the classic leukemia mutation, the Philadelphia Chromosome. ... When Chromosome 9 and 22 switch at this place, BCR becomes fused to the gene ABL, making cells divide uncontrollably. The name ... Day 347 (Ypter-Yp11.2): the Y chromosome, Nettie Stevens, and SRY * Day 346 (19q13.33-19q13.43): the most genes of any day, ... Day 356 (22q11.1-22q11.23): the Philadelphia chromosome breakpoint. http://philadelphiaift.org/. Day 356 has 123 protein-coding ...
http://www.genomeyear.net/day-356-22q11-1-22q11-23-the-philadelphia-chromosome-breakpoint/
*  Prediction and identification of recurrent genomic rearrangements that generate chimeric chromosomes in Saccharomyces...
Identification of Chimeric Chromosome Break Points.. As schematized in Fig. 1, the presence of chimeric chromosomes in an S. ... When the PCR is performed using forward primers from one chromosome and reverse primers from another chromosome, the break ... Two chromosomes sharing an identical repeated sequence are shown. Orange, chromosome A (CHR A); purple, chromosome B (CHR B); ... The break points expected to be present in the chimeric chromosomes were analyzed using a PCR-based approach. Of the seven ...
https://www.pnas.org/content/116/17/8445
*  Caracterização de rearranjos cromossômicos em pacientes com malformações congênitas...
On chromosome 14 the breakpoint was mapped to a segment contained in BAC RP11-315O17 (14q31.3). On the chromosome 5 the ... The breakpoint on chromosome 15 was mapped to the segment contained in clone RP11-152F13 (15q25.2). The breakpoint on ... The genes mapped at the breakpoint regions of chromosome 1 and chromosome 15 are expressed in nervous system and muscles. Our ... breakpoint was mapped to a segment contained in BAC RP11-30D15 (5q14.1). Although the breakpoint, on the chromosome 14, has ...
http://www.teses.usp.br/teses/disponiveis/41/41131/tde-08072008-110038/pt-br.php
*  Myeloid- and lymphoid-specific breakpoint cluster regions in chromosome band 13q14 in acute leukemia.
These data indicate the presence of myeloid- and lymphoid-specific breakpoint cluster regions within chromosome band 13q14 in ... Myeloid- and lymphoid-specific breakpoint cluster regions in chromosome band 13q14 in acute leukemia. 1999, 25 (3):222-9 Genes ... Analysis of balanced rearrangements of chromosome 6 in acute leukemia: clustered breakpoints in q22-q23 and possible ... Myeloid- and lymphoid-specific breakpoint cluster regions in chromosome band 13q14 in acute leukemia.. ...
https://christie.openrepository.com/handle/10541/88018
*  Distribution of HERV susceptibility regions. Percentage | Open-i
Percentage of each chromosome consisting of potential HERV susceptibility regions. HERV, human endogenous retroviru ... Percentage of each chromosome consisting of potential HERV susceptibility regions. HERV, human endogenous retrovirus. Mentions: ... Breakpoint sequencing revealed clustering in regions of high sequence identity enriched in PRDM9-mediated recombination hotspot ... Chromosome 19 was determined to have the largest fraction of reference sequences within susceptibility regions as a percentage ...
https://openi.nlm.nih.gov/detailedresult.php?img=PMC4195946_12915_2014_74_Fig2_HTML&req=4
*  Breakpoint mapping positions the callipyge gene within a 450-kilobase chromosome segment containing the DLK1 and GTL2 genes,...
"Breakpoint mapping positions the callipyge gene within a 450-kilobase chromosome segment containing the DLK1 and GTL2 genes, ... Breakpoint mapping positions the callipyge gene within a 450-kilobase chromosome segment containing the DLK1 and GTL2 genes. ... Breakpoint mapping positions the callipyge gene within a 450-kilobase chromosome segment containing the DLK1 and GTL2 genes. ... Breakpoint mapping positions the callipyge gene within a 450-kilobase chromosome segment... Berghmans, Stéphane ; Segers, Karin ...
https://www.deepdyve.com/lp/springer_journal/breakpoint-mapping-positions-the-callipyge-gene-within-a-450-kilobase-FOSTVHphyf
*  PMS2-related genes flank the rearrangement breakpoints associated with Williams syndrome and other diseases on human chromosome...
... but the human PMS2L genes have not been positioned in the context of the physical or genetic map of chromosome 7. In this study ... have been localized to human chromosome 7. Human PMS2 has been mapped previously to 7p22 and shown to be causative in ... be present at at least three sites as part of duplicated genomic segments that flank the most common rearrangement breakpoints ... PMS2-related genes flank the rearrangement breakpoints associated with Williams syndrome and other diseases on human chromosome ...
https://www.semanticscholar.org/paper/PMS2-related-genes-flank-the-rearrangement-with-and-Osborne-Herbrick/d4d56c5a1a8e28cf755326a87594aac9b2f911f9
*  Ghent University Academic Bibliography
Characterization of the chromosome breakpoints in a patient with a constitutional translocation T(1-17)(P36.31-P36.13-Q11.2-Q12 ... OF SOMATIC-CELL HYBRIDS AND IDENTIFICATION OF PND/A12M2 ON CHROMOSOME-1 AND NF1/SCYA7 ON CHROMOSOME-17 AS BREAKPOINT FLANKING ... HIGH-RESOLUTION FLUORESCENCE MAPPING OF 43 DNA MARKERS TO CHROMOSOME BAND-1P36 Nadine Van Roy (UGent) , P VANDERDRIFT, ... HIGH-RESOLUTION FLUORESCENCE MAPPING OF 46 DNA MARKERS TO THE SHORT ARM OF HUMAN CHROMOSOME-1. Nadine Van Roy (UGent) , ...
https://biblio.ugent.be/publication?limit=250&q=author%3D%22OPDENAKKER%2C+G%22+or+
*  High-resolution profiling of histone methylations in the human genome. - PubMed - NCBI
Chromosome banding patterns are correlated with unique patterns of histone modifications. Chromosome breakpoints detected in T ...
https://www.ncbi.nlm.nih.gov/pubmed/17512414?dopt=Abstract
*  Michael Amylon | Stanford Medicine Profiles
In addition, the SUP-B7 cells possess a single chromosome abnormality: del(3)(q26q28), with the chromosome breakpoint at or ... chromosome abnormality and a third patient with a complex three-way translocation involving the same breakpoints on chromosomes ... A common pattern with chromosome breakpoints involving TCR genes may be emerging in T cell neoplasia. ... Five cases showed the ALL breakpoint, while one child with Ph1/-7 showed the chronic myelogenous leukemia breakpoint. The ...
https://med.stanford.edu/profiles/michael-amylon
*  NOT A CHIMP: 19/04/09 - 26/04/09
Chromosome breakpoints contribute to genetic variation. In chapters 6 and 7 of NOT A CHIMP I explain how large structural ... True, our chromosome 2 is a combination of two chimp chromosomes - giving humans a complement of 23 chromosome pairs to 24 in ... To look at the complete set of human chromosomes, side by side with chimpanzee chromosomes, at the level of resolution of a ... However, look at a recent map of the chromosomes of chimps and humans, aligned side by side, produced by researchers who have ...
http://notachimp.blogspot.ca/2009_04_19_archive.html
*  Genetic and Medical Glossary - alphabetical vocabulary listing
Chromosome breakpoints. locations on a chromosome where DNA might get deleted, inverted, or swapped around ... the numerical chromosomes (chromosomes 1-22); humans have forty-four -one set from each parent; chromosome 1 is the largest and ... Acrocentric chromosome. a chromosome with its centromere near one end; includes chromosomes 13, 14, 15, 21 and 22 which all ... Sex chromosomes. chromosomes carrying the genes responsible for determining the sex of offspring, in humans the sex chromosomes ...
https://chromodisorder.org/genetic-and-medical-glossary/
*  Plasmodium falciparum parasites lacking histidine-rich protein 2 and 3: a review and recommendations for accurate reporting |...
Scherf A, Mattei D: Cloning and characterization of chromosome breakpoints of Plasmodium falciparum: breakage and new telomere ... Illustration of chromosome breakage points within and flanking the pfhrp2 gene and re-joining of the chromosome. ... It does not matter on which chromosome these genes are located as the purpose is to verify the quality of DNA in the sample. ... This is designed to detect both entire and partial gene deletions based on known chromosome breaking points, See Figure 1 (many ...
https://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-13-283
*  High-Resolution Single Nucleotide Polymorphism Array Analysis of Epithelial Ovarian Cancer Reveals Numerous Microdeletions and...
15 chromosome breakpoints, 11 samples), those with an intermediate breakpoint index (33-305 breakpoints, 18 samples), and rare ... Distribution of breakpoint indices, comparing low breakpoint index with intermediate/high breakpoint index ... which had 181 breakpoints but only one large-scale chromosome copy number change. These tumors may have alternate chromosome ... Analysis of chromosome breakpoints in neuroblastoma at sub-kilobase resolution using fine-tiling oligonucleotide array CGH. ...
http://clincancerres.aacrjournals.org/content/13/16/4731.long
*  Transcription-replication conflicts at chromosomal fragile sites-consequences in M phase and beyond | Springer for Research &...
Hecht F, Glover TW (1984) Cancer chromosome breakpoints and common fragile sites induced by aphidicolin. Cancer Genet Cytogenet ... Durkin SG, Glover TW (2007) Chromosome fragile sites. Annu Rev Genet 41:169-192PubMedCrossRefGoogle Scholar ... Fangman WL, Brewer BJ (1992) A question of time: replication origins of eukaryotic chromosomes. Cell 71:363-366PubMedCrossRef ... Chan KL, North PS, Hickson ID (2007) BLM is required for faithful chromosome segregation and its localization defines a class ...
https://rd.springer.com/article/10.1007/s00412-016-0617-2
*  Frontiers | Targeting Apoptosis Signaling Pathways for Anticancer Therapy | Oncology
Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 226, 1097-1099. ... the chromosomal location of the two agonistic TRAIL receptors on chromosome 8p is frequently altered in human cancers, e.g., by ...
https://www.frontiersin.org/articles/10.3389/fonc.2011.00023/full
*  Bertil Glader | Stanford Medicine Profiles
In addition, the SUP-B7 cells possess a single chromosome abnormality: del(3)(q26q28), with the chromosome breakpoint at or ... In CML the translocation breakpoint on chromosome 22 is within the breakpoint cluster region, while in childhood ALL, no ... PHILADELPHIA CHROMOSOME-POSITIVE ACUTE LYMPHOBLASTIC-LEUKEMIA CELL-LINES WITHOUT CLASSICAL BREAKPOINT CLUSTER REGION ... A common pattern with chromosome breakpoints involving TCR genes may be emerging in T cell neoplasia. ...
https://med.stanford.edu/profiles/bertil-glader
*  DNA methylation changes in murine breast adenocarcinomas allow the identification of candidate genes for human breast...
Analysis of chromosome breakpoints in neuroblastoma at sub-kilobase resolution using fine-tiling oligonucleotide array CGH ... Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland ...
https://www.deepdyve.com/lp/springer_journal/dna-methylation-changes-in-murine-breast-adenocarcinomas-allow-the-0jG6qn4Za0
*  Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes | JEM
Most lymphoid malignancies in A-T patients have karyotypic abnormalities with chromosome breakpoints clustering near antigen ... Chromosome translocations (arrows) and broken chromosomes (asterisk) are indicated. (B) Number of metaphases with chromosome 14 ... Metaphases were hybridized with red whole chromosome paint (WCP) for chromosome 14 and green WCP for chromosome 15, which ... 5) (18). In contrast, only 4% of TCRαsJ/sJ:Atm−/− αβ T cells had chromosome 14 aberrations (Fig. 5). Notably, the chromosome 14 ...
http://jem.rupress.org/content/204/6/1371.full
*  DNA- methylation changes in a human cell model of breast cancer progression
A recurrent chromosome breakpoint in breast cancer at the NRG1/neuregulin 1/heregulin gene. Cancer Res. 2004;64:6840-6844. [ ... Birnbaum D, Adelaide J, Popovici C, Charafe-Jauffret E, Mozziconacci MJ, Chaffanet M. Chromosome arm 8p and cancer: a fragile ... High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of ... Loss of chromosome 8p, where NRG1 is located, is one of the most frequent genomic events reported in epithelial cancers ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC2872054/?lang=en-ca