Recombination between small X chromosome duplications and the X chromosome in Caenorhabditis elegans. | Genetics
Recombination between small X chromosome duplications and the X chromosome in Caenorhabditis elegans.. R K Herman and C K Kari ... Recombination between small X chromosome duplications and the X chromosome in Caenorhabditis elegans.. R K Herman and C K Kari ... Recombination between small X chromosome duplications and the X chromosome in Caenorhabditis elegans.. R K Herman and C K Kari ... Recombinant duplications and recombinant X chromosomes were both recovered. Recombination with the X chromosome in the unc-1- ...
The DrosDel Collection | Genetics
These chromosome rearrangements include both deficiencies and duplications (Figure 6). Since the insertion site of any P ... There is no balancer for the fourth chromosome, but the lack of recombination on this chromosome meant that the two recessive ... These lines were isogenic for the X, second, and third chromosomes. The fourth chromosome was not isogenized. The six ... Another would be to balance the deletion with a suitable duplication. Such duplications can be constructed as the reciprocal ...
LINKAGE RELATIONSHIPS OF 19 ENZYME LOCI IN MAIZE | Genetics
Thus, segments of chromosomes 1 and 5 and segments of 6 and 8 may represent duplications on nonhomologous chromosomes. ... Similarly, linkages between Idh1 and Mdh1, about 22 map units apart on chromosome 8, and between Mdh2 and Idh2, less than 5 map ... Six loci are on the long arm of chromosome 1. The arrangement is (centromere)-Mdh4-mmm-Pgm1-Adh1-Phi-Gdh1, with about 46% ... These localizations should assist in the construction of additional useful chromosome marker stocks, especially since several ...
On the components of segregation distortion in Drosophila melanogaster. IV. Construction and analysis of free duplications for...
In this study we have constructed a collection of marked free duplications for the centromeric region of a second chromosome ... When two Rsps-bearing chromosomes are present within the same spermatocyte nucleus an SD chromosome is capable of causing ... Male Drosophila heterozygous for an SD-bearing second chromosome and a normal homolog preferentially transmit the SD chromosome ... Construction and analysis of free duplications for the Responder locus. Message Subject (Your Name) has forwarded a page to you ...
A High-Density Genetic Recombination Map of Sequence-Tagged Sites for Sorghum, as a Framework for Comparative Structural and...
... suggests ancestral duplication of sorghum chromosomes or chromosomal segments. Theor. Appl. Genet. 87: 925-933. ... Most maize chromosomes correspond to nonoverlapping regions of only one sorghum chromosome but most sorghum chromosomes ... shows remarkably little correspondence to any maize chromosome (just a small portion of maize chromosome 4). This hints at the ... On most chromosomes, at least one significant concentration of loci appears to correspond to the centromeric region. We have ...
Comparative Mapping of the Barley Ppd-H1 Photoperiod Response Gene Region, Which Lies Close to a Junction Between Two Rice...
The BAC sequences containing the R411 homologs were within the extensive duplication of Arabidopsis chromosomes 2 and 4 ... Comparative maps of the Ppd-H1 region of barley chromosome 2HS in relation to rice chromosome 7 and maize chromosomes 2 and 7. ... Comparative maps of rice chromosome 3, barley chromosome 4H, and maize chromosomes 1 and 9. Markers from the rice 3 and rice 7 ... One mapped on chromosome 1, cosegregating with Xrgr411c, and the other mapped on chromosome 9 close to PhyB2 (Figure 3). PHYB ...
Genetics of cosQ, the DNA-Packaging Termination Site of Phage λ: Local Suppressors and Methylation Effects | Genetics
... discovered spontaneous tandem duplications in λ; ∼90% of these mutations occurred on the left arm of the chromosome. Our ... Thus, increased chromosome length is a general mechanism of suppression of cosQ mutations. Increased chromosome length is ... Phage λ chromosomes are 48.5-kb duplexes with 12-base-long, single-stranded extensions at the 5′ ends of the strands. These ... Previous work had shown that the C48,477T mutation was suppressed by an increase in phage chromosome length (Cue and Feiss 1997 ...
Recombination between chromosomal IS200 elements supports frequent duplication formation in Salmonella typhimurium. | Genetics
Six copies of a small mobile genetic element IS200 are evenly distributed around the chromosome of S. typhimurium strain LT2. A ... Duplications of the his operon were almost exclusively due to recombination between repeated IS200 elements. These data add ... Tandem chromosomal duplications are unstable and are lost at high frequencies, representing a readily reversible source of ... Spontaneous tandem chromosomal duplications are common in populations of Escherichia coli and Salmonella typhimurium. They ...
Integrating Genetic Linkage Maps With Pachytene Chromosome Structure in Maize | Genetics
... single-copy FISH is particularly difficult in species such as maize that have many duplications and repetitive sequences (S ... with more recent mapping using pachytene chromosomes (e.g., rice chromosome 10, Chenget al. 2001; maize chromosome 9, Sadder ... 2000 Physical localization of single-copy sequences on pachytene chromosomes in maize (Zea mays L.) by chromosome in situ ... Because the rate of recombination varies along chromosomes, it has been difficult to relate linkage maps to chromosome ...
Characterization of the flamenco Region of the Drosophila melanogaster Genome | Genetics
B) Partial map of the 413(NP) chromosome showing the known unique sequences, the D1′-D1 duplication, and some restriction sites ... All but 1 of these FM7c, P[lyB] chromosomes, when combined in G2 females with a chromosome carrying the permissive flamOR(P) ... Further Southern blotting analyses indicated that d1 is part of an ∼6-kb tandem duplication. Both copies of the duplication, ... 1990 The effects of chromosome rearrangements on the expression of heterochromatic genes in chromosome 2L of Drosophila ...
High-Resolution Sex-Specific Linkage Maps of the Mouse Reveal Polarized Distribution of Crossovers in Male Germline | Genetics
A representative example (chromosome 5: 93-96 Mbp) is displayed in Figure 7. This region has complex segmental duplication in ... The distribution in males for single-recombinant chromosomes differs from the uniform case for all chromosomes (median P = 1.7 ... Overall, cold regions span 124.1 Mbp (≈5% of the genome), distributed along 18 chromosomes (all chromosomes except 10 and 11), ... The evolution of eutherian sex chromosomes may thus be intimately linked to chromosome-scale behavior of the recombination ...
A Screen to Identify Drosophila Genes Required for Integrin-Mediated Adhesion | Genetics
The following chromosomes were used in these tests: w ovoD1 v24 P[mini w+, FRT]101; MKRS, FLP99/+ for the X chromosome; P[mini ... The duplication Dp(1;2)v+65b was found to cover two of the alleles, allowing for the appropriate complementation tests and ... The designs of the X chromosome and the 2R screens are shown in Figure 2. The 2L and 3R chromosome arm screens and the 2R ... X chromosome mutations were initially tested for complementation to alleles of the three X chromosome PS integrin genes, ...
Genetic Analysis of the Caenorhabditis elegans MAP Kinase Gene mpk-1 | Genetics
Two of these mutations are alleles of mek-2 because they map near to mek-2 on the left region of chromosome I and fail to ... sDp3 is a chromosomal duplication that complements mutations in mpk-1 and dpy-17. Non-Dpy cross-progeny of genotype ga117 e164 ... STS mapping suggested that ga119 is linked to chromosome III. Next, we showed that ga119 fails to complement mpk-1(oz140) for ... Genetic mapping: The oz140 allele was initially mapped to the left arm of chromosome III (T. Schedl, personal communication). ...
Yeast: An Experimental Organism for 21st Century Biology | Genetics
2010 Gene duplication and the evolution of ribosomal protein gene regulation in yeast. Proc. Natl. Acad. Sci. USA 107: 5505- ... Nascent tetraploids created by the mating of two diploids are unstable: they lose whole chromosomes at a high rate, have ... 2007 Increased glycolytic flux as an outcome of whole-genome duplication in yeast. Mol. Syst. Biol. 3: 129. ... Evidence for the theory of duplication and divergence. The large number of fungal genome sequences has provided firm support ...
Sequence Organization and Conservation in sh2/a1-Homologous Regions of Sorghum and Rice | Genetics
Tandem duplication of the a1 homologue in sorghum: The a1 homologue was directly duplicated in the sh2/a1-homologous region of ... Sorghum bacterial artificial chromosome clones and subclones were as previously described (Chenet al. 1997). Restriction ... D, duplication; E, Explorer element; S-1, S-2, S-3, putative MITEs of sorghum; Sn-1, Snabo-1; Sn-2, Snabo-2; SSR, simple ... We have recently observed that the a1 tandem duplication is present in the sh2/a1-homologous region in rice, where the two a1 ...
Targeted Chromosomal Translocations and Essential Gene Knockout Using CRISPR/Cas9 Technology in Caenorhabditis elegans |...
C. elegans chromosomes contain specialized regions called pairing centers that localize at the end of each chromosome and ... A series of strains with particular chromosomal rearrangements, such as duplications, translocations, and inversions, have been ... The allele on the wild-type chromosome is marked with red color, and the allele on the translocated chromosome is marked with ... 2005 Chromosome sites play dual roles to establish homologous synapsis during meiosis in C. elegans. Cell 123: 1037-1050. ...
Trans-Silencing by P Elements Inserted in Subtelomeric Heterochromatin Involves the Drosophila Polycomb Group Gene, Enhancer of...
The E(z) alleles that are on chromosomes marked with ebony [E(z)61, E(z)63, E(z)son2 and E(z)son3] were crossed to P(1A);+/TM3 ... The 8-bp target site duplications of TAS element DNA are indicated by the black boxes, while arrows indicate the exact ... or wild-type chromosome) or the TM3 balancer chromosome. Grey vertical bars represent the activities of ovaries from females ... chromosome and not the balancer chromosome. Black vertical bars represent the data from progeny that inherited the balancer ...
Trans-Kingdom Transposition of the Maize Dissociation Element | Genetics
Preston, C. R., J. A. Sved and W. R. Engels, 1996 Flanking duplications and deletions associated with P-induced male ... McClintock, B., 1951 Chromosome organization and genic expression. Cold Spring Harbor Symp. Quant. Biol. 16: 13-47. ... A Deletion at the Mouse Xist Gene Exposes Trans-effects That Alter the Heterochromatin of the Inactive X Chromosome and the ... Moreover, the Ds insertions were flanked by the classic 8-bp direct duplication of the target site, typically accompanying Ds ...
No Accelerated Rate of Protein Evolution in Male-Biased Drosophila pseudoobscura Genes | Genetics
Parisi, M., R. Nuttall, D. Naiman, G. Bouffard, J. Malley et al., 2003 Paucity of genes on the Drosophila X chromosome showing ... Torgerson, D. G., and R. S. Singh, 2004 Rapid evolution through gene duplication and subfunctionalization of the testes- ... The XR chromosome of D. pseudoobscura is originated by translocation from an autosome (3L) in D. melanogaster. Hence, we were ... Contrary to the case in D. melanogaster, the ratio of male-biased genes to unbiased genes did not differ between X chromosomes ...
The Paternal Gene of the DDK Syndrome Maps to the Schlafen Gene Cluster on Mouse Chromosome 11 | Genetics
The LOC435271 gene lies within the oldest detected duplication while the Slfn1 gene is flanked by the newest. Further evidence ... de La Casa-Esperón, E., J. C. Loredo-Osti, F. Pardo-Manuel de Villena, T. L. Briscoe, J. M. Malette et al., 2002 X chromosome ... The Paternal Gene of the DDK Syndrome Maps to the Schlafen Gene Cluster on Mouse Chromosome 11. *Timothy A. Bell * , 1 , ... we identified chromosomes that were recombinant in the Om region and assayed the fertility of males carrying these chromosomes ...
CRISPR/Cas9-Targeted Mutagenesis in Caenorhabditis elegans | Genetics
This can result from the presence of a repeated sequence, and we speculate that DSB repair resulted in the duplication of a ... expressing the sgRNA under control of the regulatory sequences of an RNA polymerase III transcribed U6 snRNA on chromosome III ...
Chromosomal Inversion Polymorphism Leads to Extensive Genetic Structure | Genetics
DNA was labeled with 16-bio-dUTP and in situ hybridized on polytene chromosomes of D. subobscura according to Segarra and Aguad ... Cirera, S., and M. Aguadé, 1998 Molecular evolution of a duplication: the sex-peptide (Acp70A) gene region of Drosophila ... Indeed, the high level of interlocus LD detected in the total sample of OST and O3+4 chromosomes (Figure 4) indicates that the ... Segarra, C., and M. Aguadé, 1992 Molecular organization of the X chromosome in different species of the obscura group of ...
Experimental Evolution of Bacillus subtilis Reveals the Evolutionary Dynamics of Horizontal Gene Transfer and Suggests Adaptive...
In order to test whether HGT events detected in the evolved populations are clustered around the chromosome, a randomization- ... a generation was determined as a duplication in the OD value throughout the growth measurement). This procedure was repeated ... We turned to investigate whether HGT fragments and point mutations were clustered next to one another around the chromosome, ... 2014 Extensive cotransformation of natural variation into chromosomes of naturally competent Haemophilus influenzae. G3 ( ...
Mechanisms of Haploinsufficiency Revealed by Genome-Wide Profiling in Yeast | Genetics
If this is the case, the evolutionary cost of maintaining the duplications should outweigh the costs of producing additional ... screen for TWIST mutations in patients with craniosynostosis identifies a new microdeletion syndrome of chromosome band 7p21.1 ... For example, there may be evolutionary benefits for maintaining duplications to buffer the cell from the deleterious effects of ... 1999 Altered dosage of the Saccharomyces cerevisiae spindle pole body duplication gene, NDC1, leads to aneuploidy and ...
Adaptive Plasmid Evolution Results in Host-Range Expansion of a Broad-Host-Range Plasmid | Genetics
The sequence data for the two pDH plasmids showed a second genetic change, a duplication of the orfE-like integron gene ... Given this short time period, the underlying mechanism is most likely a single genetic change in the host chromosome. The poor ... Since the genes in the integron are under the control of a general promoter, we examined if this gene duplication affected ...