A chromosome band present on 1q. National Institutes of Health. Create AlertAlert. ... CONTEXT Chromosome 1q42 is among several genomic regions showing replicated evidence of linkage with schizophrenia, but the… ... Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain- ... Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. ...