t(11;12)(p15;p13) NUP98/KDM5A
Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion.. 5. 33832921. 2021. Clinical impact of genomic ... 1722 amino acids; 196 kD; retinoblastoma binding protein 2. Lysine-specific histone 3 demethylase; involved in chromatin- ...
t(7;21)(p15;q22) RUNX1/?
Role of ATP-dependent chromatin remodelers in hematopoietic stem and progenitor cell maintenance.. 0. ...
t(3;11)(q21;q23) KMT2A/EEFSEC
... including histones in the HOX area for allowing chromatin to be open to transcription. MLL is cleaved by taspase 1 into 2 ...
Skin: Spitz tumors
More recently, BAP1 has been shown to play a role in chromatin modification by forming part of multi-protein complexes (such as ... Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic ... Maturation (decrease in nuclear size of melanocytes with chromatin becoming darker accompanied by reduction in the amount of ...
del(13q) in chronic lymphocytic leukemia
... chromatin, and without discernible nucleoli. There is a narrow border of clear to slightly basophilic cytoplasm. ...