Loading...
*  Chorismic acid - Wikipedia
The name chorismic acid derives from a classical Greek word, χωρίζω meaning "to separate", because the compound plays a role as ... Chorismic acid, more commonly known as its anionic form chorismate, is an important biochemical intermediate in plants and ... 3-Dihydroxybenzoic acid (DHB) used for enterobactin biosynthesis The plant hormone salicylic acid Many alkaloids and other ... Wildermuth MC, Dewdney J, Wu G, Ausubel FM (2001). "Isochorismate synthase is required to synthesize salicylic acid for plant ...
https://en.wikipedia.org/wiki/Chorismic_acid
*  Chorismic acid from Enterobacter aerogenes ≥80% | Sigma-Aldrich
Chorismic acid from Enterobacter aerogenes ,=80%; CAS No.: 617-12-9; Synonyms: trans-3-([1-Carboxyethenyl]oxy)-4-hydroxy-1,5- ... Chorismic acid from Enterobacter aerogenes ≥80% Synonym: trans-. 3-. ([1-. Carboxyethenyl]. oxy). -. 4-. hydroxy-. 1,5- ... Chorismic acid is a metabolite generally used in the study of chorismate-prephenate rearrangement and to synthesize chorismate ... Building Blocks, C10, Carbonyl Compounds, Carboxylic Acids, Chemical Synthesis, Organic Building Blocks ...
https://www.sigmaaldrich.com/catalog/product/ALDRICH/C1761?lang=en®ion=US
*  bmse000075 Chorismic Acid at BMRB
Chorismic Acid. Chorismic Acid bmse000075 - Data bmse000998 - Data bmst000056 - Theory Chorismic Acid synonyms. 1,5- ... Cyclohexadiene-1-carboxylic acid, 3-((1-carboxyethenyl)oxy)-4-hydroxy-, (3R-trans)-; CHORISMIC ACID; Chorismate; Chorismic acid ... A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules Member of ... 3R,4R)-3-(1-carboxyethenoxy)-4-hydroxy-cyclohexa-1,5-diene-1-carboxylic acid. ...
http://bmrb.wisc.edu/metabolomics/mol_summary/?molName=Chorismic+acid
*  Pyocyanin - Wikipedia
Chorismic acid is the precursor of pyocyanin. shikimic acidchorismic acid → phenazine-1-carboxylic acid → 5-methylphenazine- ... of the hydroxyl group from C4 of Chorismic Acid as well as the transfer of an amine group from glutamine to form glutamic acid ... Biosynthesis can be impaired by disrupting the aro pathway which is responsible for the synthesis of chorismic acid from ... 6-carboxylic acid (THPCA).[20] In the final step of phenazine-1-carboxylic acid synthesis the enzyme PhzG catalyzes the ...
https://en.wikipedia.org/wiki/Pyocyanin
*  IJMS | Free Full-Text | Noncanonical Reactions of Flavoenzymes | HTML
In these enzymes, the flavin plays either a direct role in acid/base reactions or as a nucleophile or electrophile. In addition ... Hill, R.K.; Newkome, G.R. Stereochemistry of chorismic acid biosynthesis. J. Am. Chem. Soc 1969, 91, 5893-5894. [Google Scholar ... acting as either an acid or a base, or functioning as both an acid and a base [44]. A role for the reduced FMN in charge ... such as both an acid and a base, in electron transfer and acid/base reactions, and as a molecular scaffold forming a covalent ...
http://www.mdpi.com/1422-0067/13/11/14219/htm
*  Quantitative Metabolomics Reveals an Epigenetic Blueprint for Iron Acquisition in Uropathogenic Escherichia coli
Interestingly, the yersiniabactin and salmochelin biosynthetic pathways converge at chorismic acid, where each pathway uses ... Figure 6. Biosynthesis of siderophores associated with recurrent UTI depends on chorismic acid utilization. ... formic acid) was held constant at 95% and solvent B (80% acetonitrile in 0.1% formic acid) was held constant at 5% for 5 ... formic acid in 10% acetonitrile. Siderophores were eluted following application of 2 mL of 0.1% formic acid in 80% acetonitrile ...
http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1000305
*  Pseudomonas aeruginosa - Wikipedia
These operons convert a chorismic acid to the phenazines mentioned above. Three key genes, phzH, phzM, and phzS convert ... This matrix is composed of nucleic acids, amino acids, carbohydrates, and various ions. This matrix is one of the main ... However, salicylic acid can inhibit pyocyanin production. One in ten hospital-acquired infections is from Pseudomonas. Cystic ... Martínez C, Pons E, Prats G, León J (January 2004). "Salicylic acid regulates flowering time and links defence responses and ...
https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa
*  Vibriobactin - Wikipedia
DHB is synthesized from chorismic acid by a series of enzymes: VibA, VibB, and VibC. DHB is linked to NSPD by VibE, VibB and ... The components of vibriobactin are three 2,3-dihydroxybenzoic acid (DHB), two threonine (Thr), and one norspermidine (NSPD). ...
https://en.wikipedia.org/wiki/Vibriobactin
*  Phenazine - Wikipedia
Phenazine biosynthesis branches off the shikimic acid pathway at a point subsequent to chorismic acid. Two molecules of this ... Sulfuric acid dissolves it, forming a deep-red solution. Classically phenazine are prepared by the reaction of nitrobenzene and ... When heated with concentrated hydrochloric acid the amino group is replaced by the hydroxyl group and the phenolic eurhodols ... It dissolves in concentrated sulfuric acid with a yellowish-green fluorescence. The rhodamines, which are closely related to ...
https://en.wikipedia.org/wiki/Phenazine
*  Prephenate dehydratase - Wikipedia
ENZYMES CONVERTING CHORISMIC ACID INTO PREPHENIC ACID AND THEIR RELATIONSHIPS TO PREPHENATE DEHYDRATASE AND PREPHENATE ... CERUTTI P, GUROFF G (1965). "ENZYMATIC FORMATION OF PHENYLPYRUVIC ACID IN PSEUDOMONAS SP. (ATCC 11299A) AND ITS REGULATION". J ...
https://en.wikipedia.org/wiki/Prephenate_dehydratase
*  Pseudomonas aeruginosa manipulates redox and iron homeostasis of its microbiota partner Aspergillus fumigatus via phenazines
... which is produced from chorismic acid. PCA is further modified in pyocyanin (PYO), 1-hydroxyphenazine (1-HP), or phenazine-1- ... The acetic acid was removed to clean 96 well plates and the absorbance at 560 nm was measured (Thermo Labsystems Multiskan EX). ... The biofilms were destained by the addition of 130 μl of 30% acetic acid in water to each well for 20 min under agitation at ... Wang Y. et al. Phenazine-1-carboxylic acid promotes bacterial biofilm development via ferrous iron acquisition. J. Bacteriol. ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC5389140/
*  Glucobrassicin - Wikipedia
... chorismic acid. Tryptophan is converted to indole-3-acetaldoxime (IAOx) by cytochrome p450 enzymes (the redundant CYP92B3 and ... The biosynthesis of glucobrassicin begins with tryptophan produced through several steps from the Shikimic acid pathway ...
https://en.wikipedia.org/wiki/Glucobrassicin
*  Rubicordifolin - Wikipedia
Shikamate is converted into chorismic acid, which is further converted into 2-succinylbenzoic acid through a TPP dependent ... After 2-succinylbenzoic acid has been produced, a cyclization, a prenylation, a methylation, and an oxidation occur which ... Mechanistically, it is proposed that the phenylboronic acid promotes a cyclization that is followed by a Diels-Alder reaction ...
https://en.wikipedia.org/wiki/Rubicordifolin
*  US20170211104A1 - Biosynthetic production of acetaminophen, p-aminophenol, and p-aminobenzoic acid - Google Patents
... and p-aminobenzoic acid and the purification of biologically derived acetaminophen. ... i. chorismic acid to p-aminobenzoic acid (PABA) (pathway step a);. *ii. p-aminobenzoic acid to p-aminophenol (pathway step b); ... The strains encode enzymes that convert the native yeast metabolite chorismic acid to p-aminobenzoic acid, p-aminobenzoic acid ... chorismic acid to p-aminobenzoic acid (PABA) (pathway step a); ii. p-aminobenzoic acid to p-aminophenol (pathway step b); and ...
https://patents.google.com/patent/US20170211104A1/en
*  Enterobactin - Wikipedia
Chorismic acid, an aromatic amino acid precursor, is converted to 2,3-dihydroxybenzoic acid (DHB) by a series of enzymes, EntA ... These initial studies established the structure and its relationship to 2,3-dihydroxybenzoic acid. Dertz, Emily A., Jide Xu, ... 3-dihydroxybenzoic acid and serine formed by Escherichia coli". Biochim Biophys Acta. 201 (3): 453-60. doi:10.1016/0304-4165(70 ...
https://en.wikipedia.org/wiki/Enterobactin
*  Dictionary Of Biochemistry And Molecular Biology by J. STENESH - Carlos Bezerra Library
anthranilic acid See chorismic acid. anthrone reaction A colorimetric reaction for carbohydrates, particularly hexoses, that is ...
http://carlosbezerrajr.com.br/index.php/pdf/dictionary-of-biochemistry-and-molecular-biology
*  Frontiers | Microbial effectors target multiple steps in the salicylic acid production and signaling pathway | Plant Science
Among these, salicylic acid signaling is an important pathway because of its ability to trigger plant cell death. As biotrophic ... Here we review the strategies prokaryotic pathogens have developed to target salicylic acid biosynthesis and signaling, and ... Here we review the strategies prokaryotic pathogens have developed to target salicylic acid biosynthesis and signaling, and ... they have evolved efficient strategies to downregulate salicylic acid signaling by virulence effectors, which can be proteins ...
https://www.frontiersin.org/articles/10.3389/fpls.2015.00349/full
*  Defensive Secretion
Figure 8.5 Aromatic compounds from chorismic acid. Mechanism a in the top left structure leads to anthranilic acid and ... The route from chorismic acid to tryptophan is found in plants and micro-organisms only. Glomerine is a millipede defensive ... Indole and skatole are used in various insects as pheromones Figure 8.5 Aromatic compounds from chorismic acid. Mechanism a in ... Figure 10.18 Dihydromatricaria acid is found in cantharid beetles feeding on Compositae which contain polyacetylenic acids. ...
https://www.phrygane.tk/defensive-secretion/
*  PowToon - Biology 1 Chapter 16- Gene Expression
... coli controls the biosynthesis of tryptophan in the cell from the initial precursor chorismic acid. This operon contains genes ... When the amino acid is not there, the repressor moves away from the operator and RNA synthesis continues.'(Lumen, 2007) ... The genetic code describes the relationship between the sequence of base pairs in a gene and the corresponding amino acid ... molecule to a sequence of amino acids during protein synthesis. ... Transcription will occur at a lower rate.''When an amino acid ...
https://www.powtoon.com/online-presentation/dPnlUJTVjaZ/?mode=movie
*  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase - Wikipedia
From these six genes, EntA, EntB, and EntC are responsible for the synthesis of DHB from chorismic acid and the gene EntA ... Young, IG (1969). "Regulation of the enzymes involved in the biosynthesis of 2,3-dihydroxybenzoic acid in Aerobacter aerogenes ... 28 April 2006). "Determination of the crystal structure of EntA, a 2,3-dihydro-2,3-dihydroxybenzoic acid dehydrogenase from ... 3-dihydroxybenzoic acid (2,3-DHB or simply DHB). In times of iron deficiency, iron uptake is controlled by three genes: ent, ...
https://en.wikipedia.org/wiki/2,3-dihydro-2,3-dihydroxybenzoate_dehydrogenase
*  Metabolic engineering for the production of shikimic acid in an evolved Escherichia coli strain lacking the phosphoenolpyruvate...
... chorismic acid; QA, quinic acid; PCA, protocatehuic acid; GA, gallic acid. Genes and coded enzymes: tktA, transketolase I;pykF ... 3-dehydroquinic acid; DHS, 3-dehydroshikimic acid; SA, shikimic acid; S3P, shikimate-3-P; EPSP, 5-enolpyruvylshikimate-3- ... Draths KM, Knop DR, Frost JW: Shikimic acid and quinic acid: replacing isolation from plant sources with recombinant microbial ... SHK-3P is then transformed to chorismic acid (CHA) (Figure 1).. SA is used as the precursor for the synthesis of a large number ...
https://microbialcellfactories.biomedcentral.com/articles/10.1186/1475-2859-9-21
*  Inhibition of Shikimate Kinase and Type II Dehydroquinase for Antibiotic Discovery: Structure-Based Design and Simulation...
... also known as the shikimic acid pathway, in which chorismic acid is synthesized. The latter compound is the synthetic precursor ... also known as the shikimic acid pathway, in which chorismic acid is synthesized. The latter compound is the synthetic precursor ... effort has been focused on the discovery of new inhibitors of the enzymes involved in the biosynthesis of aromatic amino acids ... effort has been focused on the discovery of new inhibitors of the enzymes involved in the biosynthesis of aromatic amino acids ...
http://www.eurekaselect.com/134331/article
*  Publications
Chorismic acid is the major branch point in the synthesis of aromatic amino acids, ubiquinone, and secondary metabolites. The ... Shikimate Pathway is a seven-step biosynthetic route which generates chorismic acid. The shikimate pathway is essential for ... Shikimate pathway is a seven step biosynthetic route which generates chorismic acid from phosphoenol pyruvate and erythrose-4- ... a site where a non-protein amino-acid, alpha-aminobutyric acid (Abu), is bound. RESULTS: The overall structure of native CGL ...
http://azevedolab.net/publications.php
*  GMD - Chorismic acid barium salt - InChI=1S/C10H10O6.Ba/c1-5(9(12)13)16-8-4-6(10(14)15)2-3-7(8)11;/h2-4,7-8,11H,1H2,(H,12,13)(H...
Details Chorismic acid barium salt. rotate: click+drag; translate: alt. +click+drag; zoom: mousewheel; save: mol ... Replica of Chorismic acid barium salt. reference substance. supplier. supplier code. lot. ... trans-3-[(1-carboxyethenyl)oxy]-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid Barium Salt. ... Mans-3(1-Carboxyethenyl)oxy)]-4-hydroxy-1,5-cyclohexdiene-1-carboxylic acid). ...
http://gmd.mpimp-golm.mpg.de/ReferenceSubstances/41EA7C33-23D2-4960-BE2D-898CA11D6D23.aspx