Cancers | Free Full-Text | Epigenetic Therapy in Human Choriocarcinoma
In this review, we discuss the biologic and therapeutic effects of HDACIs in treating choriocarcinoma, with a special focus on ... and the expression of genes related to the malignant phenotype in choriocarcinoma cell lines. ... are believed to be involved in the repression of tumor suppressor genes and promotion of tumorigenesis in choriocarcinomas, ... Keywords: choriocarcinoma; epigenetics; histone deacetylase inhibitors choriocarcinoma; epigenetics; histone deacetylase ...http://www.mdpi.com/2072-6694/2/3/1683
Gestational choriocarcinoma - Wikipedia
"Choriocarcinoma". Retrieved 10 August 2012. NIH. "Choriocarcinoma". Retrieved 10 August 2012. NIH. "Choriocarcinoma". Retrieved ... Gestational choriocarcinoma is a malignant trophoblastic tumour arising from any gestational event during pregnancy in the ... Women with gestational choriocarcinoma may present with abnormal vaginal bleeding, persistent markedly elevated βhCG, or a ... Most patients develop gestational choriocarcinoma shortly after gestational anomalies, but pathology may occur after a long ...https://en.wikipedia.org/wiki/Gestational_choriocarcinoma
Abstract #4106: Activation of PKB/AKT promotes cell survival and invasion in choriocarcinoma | Cancer Research
Abstract #4106: Activation of PKB/AKT promotes cell survival and invasion in choriocarcinoma. Hui-Juan Zhang, Michelle Siu, ... Methods: Choriocarcinoma cell lines JEG-3 and JAR were treated with PI3K inhibitor LY294002 and possible change in p-PKB (Ser ... However, the role of activated PI3K/PKB in choriocarcinoma is not reported yet. In this study, we investigated the expression ... Immunohistochemical analysis in choriocarcinoma tissue samples confirmed significantly higher p-PKB (Ser473) expression ...http://cancerres.aacrjournals.org/content/69/9_Supplement/4106
A Rare Cause of Massive Hemoptysis: Bilateral Endobronchial Lesions Secondary to Metastatic Gestational Choriocarcinoma in a...
Choriocarcinoma usually affects premenopausal women. A postmenopausal choriocarcinoma is a rare event and there are few cases ... Two types of choriocarcinoma have been described: gestational and non-gestational. Usually, gestational choriocarcinoma occurs ... Desai N, Gupta S, Said R, Desai P, Dai Q (2010) Choriocarcinoma in a 73-year-old woman: a case report and review of the ... The tumor was diagnosed as a metastatic choriocarcinoma. The patient was G3P2A1. She had history of two male births, the last ...http://medcraveonline.com/ICPJL/ICPJL-02-00058.php
Cytotoxic activity against trophoblast and choriocarcinoma cells of large granular lymphocytes from human early pregnancy...
... purified populations of CD56-positive decidual LGL have no cytotoxic activity against either the BeWo choriocarcinoma cell line ... Choriocarcinoma, Cytotoxicity, Immunologic, Decidua, Female, Humans, Immunity, Cellular, Killer Cells, Natural, Leukocytes, ... Cytotoxic activity against trophoblast and choriocarcinoma cells of large granular lymphocytes from human early pregnancy ... Cytotoxic activity against trophoblast and choriocarcinoma cells of large granular lymphocytes from human early pregnancy ...https://www.wrh.ox.ac.uk/publications/517270
Gestational Trophoblastic Disease | Memorial Sloan Kettering Cancer Center
Choriocarcinoma. A choriocarcinoma is even rarer than a hydatidiform mole. This type of GTD may have begun as a hydatidiform ... A choriocarcinoma can also spread more widely to other parts of the body such as the lungs, liver, and/or brain. ... In contrast, all choriocarcinomas, PSTTs, and ETTs are considered cancerous.. Hydatidiform Mole. A hydatidiform mole is ... A woman with an hydatidiform mole (partial or complete) or choriocarcinoma may experience one or more of these symptoms:. * ...https://www.mskcc.org/cancer-care/types/gestational-trophoblastic-disease
Gestational Trophoblastic Disease Treatment (PDQ®): Treatment - Health Professional Information [NCI] - WellSpan Health Library
Choriocarcinoma Choriocarcinoma is a malignant tumor of the trophoblastic epithelium. Uterine muscle and blood vessels are ... and they are treated similarly to choriocarcinoma (i.e., with chemotherapy). However, unlike choriocarcinoma, they may regress ... In that study, choriocarcinoma patients and patients with a risk score of 5 to 6 had a worse CR rate to initial treatment with ... Most choriocarcinomas have an aneuploid karyotype, and about three-quarters of them contain a Y chromosome. Most follow an HM ...http://www.wellspan.org/health-library/Document.aspx?id=ncicdr0000062901
Hydatidiform Mole Malignant: Complications
Complications of choriocarcinoma include: * Sepsis * Urinary tract infection * Infertility ... ... Another name for Hydatidiform Mole Malignant is Choriocarcinoma. ...http://www.freemd.com/hydatidiform-mole-malignant/complications.htm
Gestational Trophoblastic Disease Treatment (PDQ®): Treatment - Patient Information [NCI] | PeaceHealth
Choriocarcinomas. A choriocarcinoma is a malignant tumor that forms from trophoblast cells and spreads to the muscle layer of ... Invasive moles and choriocarcinomas are treated based on risk groups. The stage of the invasive mole or choriocarcinoma is one ... For example, if choriocarcinoma spreads to the lung, the cancer cells in the lung are actually choriocarcinoma cells. The ... A choriocarcinoma is more likely to form in women who have had any of the following:. *Molar pregnancy, especially with a ...https://www.peacehealth.org/medical-topics/content/nci/ncicdr0000062699.html
Treatments for gestational trophoblastic disease - Canadian Cancer Society
Gestational trophoblastic neoplasia (GTN) includes invasive moles and gestational choriocarcinoma. They are almost always ... such as an invasive mole or a choriocarcinoma), which will need to be treated further with chemotherapy. ...http://www.cancer.ca/en/cancer-information/cancer-type/gestational-trophoblastic-disease/treatment/?region=ns
Gene expression profile in human trophoblast and gestational trophoblastic disease - OpenThesis
Neoplastic transformation of trophoblast leads to gestational trophoblastic diseases (GTD). Choriocarcinoma (CCA) and ...http://www.openthesis.org/documents/Gene-expression-profile-in-human-513980.html
Hydatidiform Mole Research Paper - 1072 Words
However, a malignancy called choriocarcinoma may start from a hydatidiform mole. In its early stages, a hydatidiform mole may ... Abnormal trophoblast cells must be identified because they are associated with choriocarcinoma, a rapidly metastasizing ... Complete hydatidiform moles have a higher risk of developing into choriocarcinoma - a malignant tumor of trophoblast cells - ...http://www.studymode.com/essays/Hydatidiform-Mole-1095180.html
Classifying Molar Pregnancy - Redorbit
... and choriocarcinoma, a malignant, rapidly-growing, and metastatic form of cancer. Molar pregnancies can have either partial or ...http://www.redorbit.com/news/science/1772951/classifying_molar_pregnancy/
Immunizing with mouse trophoblast to obtain mouse-human cross-reacting antibodies against normal and neoplastic human...
... and third-trimester placentas and from hydatidiform moles and choriocarcinoma. Several mouse-human cross-reacting antibodies ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:894403
Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic...
Moreover, absence of immunoreaction for HtrA1 is observable in the choriocarcinoma cells. In conclusion, we suggest that HtrA1 ... Moreover, absence of immunoreaction for HtrA1 is observable in the choriocarcinoma cells. In conclusion, we suggest that HtrA1 ... and choriocarcinoma. In addition to that we used the western blotting technique to quantify HtrA1 immunoreaction in normal ... and choriocarcinoma. In addition to that we used the western blotting technique to quantify HtrA1 immunoreaction in normal ...https://usiena-air.unisi.it/handle/11365/8759
Treatment of Testicular Cancer, Testicular Cancer Definition, Causes, Risk Factors, Symptoms, Diagnosis & Treatment, Testicular...
Nonseminoma. This group of cancers includes choriocarcinoma, embryonal carcinoma, teratoma and yolk sac tumors. These types of ...http://www.knowyourdisease.com/treatment-of-testicular-cancer.html
Relative sensitivity to inhibition by cimetidine and clonidine differentiates between the two types of Na+-H+ exchangers in...
The JAR human placental choriocarcinoma cell line and the opossum kidney (OK) cell line, when grown as confluent monolayer ...http://www.biochemj.org/content/280/2/317
News Moms Need » complete mole
Tags: choriocarcinoma, chromosomes, complete mole, embryo, fertilized egg, gestational trophoblastic disease, GTD, hCG level, ... Rarely, a cancerous form of GTD, called choriocarcinoma, develops and spreads to other organs. Use of multiple cancer drugs is ... woman because it can occasionally result in rare pregnancy-related types of cancers called invasive mole and choriocarcinoma. ...http://newsmomsneed.marchofdimes.org/?tag=complete-mole
Partial molar pregnancy with live fetus diagnosed on second trimester: a case report
They are associated with an increase risk for the development of neoplasm, specifically choriocarcinoma, a malignant tumor that ... They are associated with an increase risk for the development of neoplasm, specifically choriocarcinoma, a malignant tumor that ...https://www.ommegaonline.org/article-details/Partial-molar-pregnancy-with-live-fetus-diagnosed-on-second-trimester-a-case-report/1475
Secular Pro-Life Perspectives: Objections to Biological Humanity from Fertilization
"an entity which is usually just a degenerated placenta and typically has a random number of chromosomes"), the choriocarcinoma ...http://blog.secularprolife.org/2013/12/objections-to-biological-humanity-from.html?showComment=1386791159949
Furthermore, Choriocarcinoma, Comprehensive Hydatidiform Mole, Immunohistochemistry Gestational trophoblastic illnesses ... rare 334951-92-7 supplier cases of choriocarcinoma possess followed incomplete hydatidiform mole ...http://researchhunt.com/category/endopeptidase-24-15/page/2/
Choriocarcinoma: Symptoms and Treatment
Choriocarcinoma is a form of cancer that occurs in the female reproductive system. The following Buzzle article elaborates more ... Choriocarcinoma is a type of cancer that develops in a woman's uterus (womb). In choriocarcinoma, the placenta that begins to ... Choriocarcinoma is a form of cancer that occurs in the female reproductive system. The following Buzzle article elaborates more ... In some cases, women after healthy delivery may also get choriocarcinoma Symptoms. The patient may not show any symptoms, until ...https://www.buzzle.com/articles/choriocarcinoma-symptoms-and-treatment.html
American Urological Association - Choriocarcinoma
Home Education AUAUniversity Education Products & Resources Pathology for Urologists Testis Germ Cell Tumors Choriocarcinoma ... Pure choriocarcinoma is very rare and accounts for ,1% of GCTs.. *Usually is mixed with other GCT components (8% of mixed GCT). ... Classic choriocarcinoma *Mixture of cytotrophoblasts (polygonal cells with clear cytoplasm, bland nucleus and prominent cell ...http://www.auanet.org/education/auauniversity/education-products-and-resources/pathology-for-urologists/testis/germ-cell-tumors/choriocarcinoma
Testicular Choriocarcinoma Medication: Antineoplastic agents
Pure choriocarcinoma of the testis is the exception to most of the rules established for testicular seminoma and all other ... Testicular choriocarcinoma is one of the histologic types of nonseminomatous germ cell tumors (NSGCTs), which along with ... Testicular Choriocarcinoma Medication. Updated: Apr 04, 2017 * Author: Michael B Williams, MD, MS; Chief Editor: Bradley Fields ... Clinicopathologic analysis of choriocarcinoma as a pure or predominant component of germ cell tumor of the testis. Am J Surg ...https://emedicine.medscape.com/article/435577-medication
A Rare Case of Metastatic Choriocarcinoma of Lung Origin
... Parth Rali,1 Jianwu Xie,2 Grishma Rali,3 Mayur Rali,4 Jan Silverman,2 ... M. Schulz, A. Hernandez, and F. Rebora, "Primary chorio-carcinoma of the lung; Case report," Rev Mex Tuberc Enferm Apar Respir ... U. B. M. Kinni, "Primary pulmonary choriocarcinoma: Is it still an enigma," Indian Journal of Chest Diseases and Allied ... X. M. Li, X. Y. Liu, and Z. X. Liu, "Choriocarcinoma with multiple lung, skull and skin metastases in a postmenopausal female: ...https://www.hindawi.com/journals/cripu/2017/4649813/ref/