Cholesterol Side-Chain Cleavage Enzyme [D08.811.682.690.708.170.915.212] * 25-Hydroxyvitamin D3 1-alpha-Hydroxylase [D08.811. ... Steroid 12-alpha-Hydroxylase [D08.811.682.690.708.170.915.730] * Steroid 16-alpha-Hydroxylase [D08.811.682.690.708.170.915.737] ... 25-Hydroxyvitamin D3 1-alpha-Hydroxylase [D12.776.422.220.453.915.400] * Steroid 12-alpha-Hydroxylase [D12.776.422.220.453.915. ... Steroid Hydroxylases [D08.244.453.915] * Cholesterol 24-Hydroxylase [D08.244.453.915.025] * Cytochrome P-450 CYP11B2 [D08.244. ...
Cholesterol 24-hydroxylase. *Cholesterol 25-hydroxylase. *Cholesterol 7-alpha-monooxygen.... *Lysosomal acid lipase/choleste... ... 3a,7a-dihydroxy-5b-cholestanoyl-CoA remains intact while alpha-methylacyl-CoA racemase moves it along through the peroxisome. ... A bile acids life begins as cholesterol is catabolized, as bile acid is a derivative of cholesterol. This pathway occurs in the ... beginning with cholesterol being converted to 7a-hydroxycholesterol through the enzyme cholesterol-7-alpha-monooxygenase, after ...
Cholesterol 25-Hydroxylase; Olr1: Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 ; Nos2: inducible Nitric Oxide ... Tumor Necrosis Factor alpha; MCP-1: Monocyte Chemotactic Protein 1; TACE: Tumor Necrosis Factor Alpha Converting Enzyme; ADAM17 ... Inter-alpha-inhibitor proteins are endogenous furin inhibitors and provide protection against experimental anthrax intoxication ... Integrin alpha M; Ly6C: Lymphocyte antigen 6C; Ly6G: Lymphocyte antigen 6G; Trem1: Triggering receptor expressed on myeloid ...
Label: cholesterol 26-hydroxylase activity Synonyms: cholesterol 26-hydroxylase activity Alternative IDs: als ... taxadien-5-alpha-ol O-acetyltransferase activity GO:0050638 * beta-amyrin monooxygenase activity ...
alpha-carotene epsilon hydroxylase activity GO:0072373 * uvaol dehydrogenase activity GO:0102373 ...
cholesterol 24-hydroxylase. 1 subfamily, 1 gene. CYP46A1 CYP51. cholesterol biosynthesis. 1 subfamily, 1 gene, 3 pseudogenes. ... steroid biosynthesis, 17-alpha hydroxylase. 1 subfamily, 1 gene. CYP17A1 CYP19. steroid biosynthesis: aromatase synthesizes ... steroid 20α-hydroxylase, steroid 22-hydroxylase, cholesterol side chain scission). ... CYP27A1 (bile acid biosynthesis), CYP27B1 (vitamin D3 1-alpha hydroxylase, activates vitamin D3), CYP27C1 (unknown function) ...
cholesterol 24-hydroxylase. 1 subfamily, 1 gene. CYP46A1 CYP51. cholesterol biosynthesis. 1 subfamily, 1 gene, 3 pseudogenes. ... steroid biosynthesis, 17-alpha hydroxylase. 1 subfamily, 1 gene. CYP17A1 CYP19. steroid biosynthesis: aromatase synthesizes ... steroid 20α-hydroxylase, steroid 22-hydroxylase, cholesterol side chain scission). ... CYP27A1 (bile acid biosynthesis), CYP27B1 (vitamin D3 1-alpha hydroxylase, activates vitamin D3), CYP27C1 (unknown function) ...
As outlined in this review, the cholesterol modulating actions of plant sterols may overlap with their anti-cancer actions. ... Plant sterols are well known for their effects on blood cholesterol levels, however research into their potential role in ... Re-expression of estrogen receptor alpha in estrogen receptor alpha-negative MCF-7 cells restores both estrogen and insulin- ... Nguyen, L.B.; Shefer, S.; Salen, G.; Tint, S.G.; Batta, A.K. Competitive inhibition of hepatic sterol 27-hydroxylase by ...
... cholesterol inside the brain is also oxidized to 27-hydroxycholesterol (27-OHC) by the sterol 27-hydroxylase (CYP27A1), that is ... to retain cholesterol homeostasis, cholesterol is converted in to the extra hydrophilic metabolite 24-OHC, also called ... take place because this oxysterol is usually a significant cholesterol metabolite in circulation along with the 27-hydroxylase ... Two other cholesterol metabolites, 7,25dihydroxycholest-4-en-3-one and 7,(25R)26-hydroxycholest-4-en-3-one, have been reported ...
... α hydroxylase. CYP8B1. sterol 12alpha-hydroxylase. DCA. deoxycholic acid. DDI. drug-drug interaction. EDC. endocrine disrupting ... hepatocyte nuclear factor 4-alpha. IFALD. intestinal failure-associated liver disease. LCA. lithocholic acid. MCA. muricholic ... BA synthesis in the liver is the primary form of cholesterol catabolism (Fig. 1). In the liver, two major pathways carry out BA ... α-hydroxylase (CYP7A1). Subsequent enzymatic reactions catalyzed by sterol 12α-hydroxylase (CYP8B1) and sterol 27-hyroxylase ( ...
Copper is also vital in producing the neurotransmitters peptidyl alpha amidating monoxygenase and dopamine hydroxylase. ... Copper is vital in producing the neurotransmitters peptidyl alpha-amidating monooxygenase and dopamine hydroxylase(3*).. ... triglycerides and serum cholesterol levels(4*). In addition, copper plays a role in iron metabolism, storage, and absorption(5 ... The signs of copper deficiency are similar to those of iron deficiency such as general malaise, and lightheadedness(6*), (7*). ...
PubMed:Alpha-glucosidase inhibitory and antihyperglycemic effects of polyphenols in the fruit of Viburnum dilatatum Thunb.. ... PubMed:Cyanidin-3-O-β-glucoside upregulates hepatic cholesterol 7α-hydroxylase expression and reduces hypercholesterolemia in ... PubMed:Cyanidin-3-O-glucoside counters the response to TNF-alpha of endothelial cells by activating Nrf2 pathway.. ... PubMed:Cyanidin-3-O-β-glucoside induces oxysterol efflux from endothelial cells: role of liver X receptor alpha.. ...
... thus indicating a relatively low 12 alpha-hydroxylase activity. Endogenous synthesis of monohydroxy bile acid ester sulfates ... thus allowing the conclusion that this monohydroxy bile acid is derived from cholesterol and should be considered together with ... 12 alpha-triol but not the -3 alpha, 7 alpha-diol was followed by an increase in cholic acid synthesis, ... D2O permitted a comparison of the precursor/product relationship of cholesterol with 3 beta-hydroxy-5-cholenoic acid. The ...
Steroid 17-alpha-hydroxylase/17,20 lyase OS=Oryzias latipes GN=cyp17a1 PE=2 SV=1. 514. 634. 5.0E-07. ... Cholesterol side-chain cleavage enzyme, mitochondrial (Fragment) OS=Dasyatis americana GN=CYP11A1 PE=2 SV=1. 513. 632. 4.0E-09 ... Taxane 13-alpha-hydroxylase OS=Taxus cuspidata GN=CYP725A2 PE=1 SV=1. 521. 640. 5.0E-07. ... Taurochenodeoxycholic 6 alpha-hydroxylase OS=Sus scrofa GN=CYP4A21 PE=1 SV=1. 516. 633. 1.0E-06. ...
Evidence for 17 alpha-hydroxylase and 17,20-lyase. Steroids. 1979; 34(7):817-27. ... Lowers Cholesterol Levels. The logic behind the cholesterol-lowering effect of pregnenolone is simple - it is manufactured ... Studies on pregnenolone support its cholesterol-lowering effects:. *In rats, administration of cholesterol substrates increases ... Pregnenolone sulphate- and cholesterol-regulated TRPM3 channels coupled to vascular smooth muscle secretion and contraction. ...
ratio and mRNA expression levels of CCAAT-/enhancer-binding protein alpha, fatty acid. synthase, lipoprotein lipase, and ... HSL), carnitine palmitoyl transferase-1b (CPT1b), peroxisome proliferator-activated receptor α (PPARα), cholesterol 7α- ... hydroxylase (CYP7A1) and low-density lipoprotein receptor (LDL-R) mRNA levels were increased by APPs, while Kelch-like ECH- ... HSL) and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) were examined by real-time PCR and ...
24-hydroxycholesterol 7alpha-hydroxylase activity. 0.00787578791194636. GO:0008387. steroid 7-alpha-hydroxylase activity. ... steroid 17-alpha-monooxygenase activity. 0.00787578791194636. GO:0004639. phosphoribosylaminoimidazolesuccinocarboxamide ... cholesterol metabolic process. 0.0158173818357916. GO:0046914. transition metal ion binding. 0.0159525915927521. GO:0015980. ... oxysterol 7-alpha-hydroxylase activity. 0.0122609094705967. GO:0044270. nitrogen compound catabolic process. 0.0125473985545729 ...
... and Cadm1b features a predicted cholesterol 24-hydroxylase activity (GO term). A total of four mRNAs encoding transporters of ... Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase July 12, 2017 ... A) Splicing isoforms of RNAs encoding proteins from the cholesterol synthesis and transport pathway have been 1st reconstructed ... mRNAs encoding proteins involved in cholesterol transport had been also alternatively spliced after injury (Figure 7A). mRNAs ...
HMG CoA reductase and cholesterol 7a-hydroxylase were assayed using tracer techniques. Our results showed that the effects of ... high density lipoprotein cholesterol, triglyceride and fasting blood glucose (FBG) were also measured. Vitamin E (alpha- ... In this study, the effect of tocotrienols and a-tocopherol on the activities of HMG CoA reductase and cholesterol 7 a- ... Nutritional status, blood pressure, lipid profiles, fasting blood glucose (FBG), vitamin E (alpha-tocopherol) levels and lipid ...
Tumor necrosis factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory ... 7] El-Nashar, H.A.S., El-labbad, E.M., Al-Azzawi, M.A., and Ashmawy, N.S., 2022, A new xanthone glycoside from Mangifera incida ... Pharm., 11 (7), 414-421.. [23] Godghate, A., Sawant, R., and Sutar, A., 2012, Phytochemical analysis of ethanolic extract of ... Wellness, 7 (2), 156-162.. [46] Weidner, S., Król, A., Karamać, M., and Amarowicz, R., 2018, Phenolic compounds and the ...
... aldrich T8700-1VL Anti-Tyrosine Hydroxylase antibody produced in rabbit 148 sigma aldrich T8700-1VL Anti-Tyrosine Hydroxylase ... ol 82 sigma aldrich R205370-1MG 5-ALPHA-CHOLESTANE 83 sigma aldrich A3656-5MG 5-Aza-2?-deoxycytidine 84 sigma aldrich N17807-5G ... 205 sigma aldrich C8667-5G Cholesterol 206 sigma aldrich C1629-100G Choline bitartrate 207 sigma aldrich C1629-100G Choline ... 2ML Monoclonal Anti-Tyrosine Hydroxylase antibody produced in mo 399 sigma aldrich D048-100MG MPP+ iodide 400 sigma aldrich ...
A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene. ... Effects of alpha-lipoic acid on biomarkers of oxidative stress in streptozotocin-induced diabetic rats. J Nutr Biochem. 2003; ... Figure 7. Apremilast reduced IL-1α-induced expressions of Myd88 and TRAF6 in ESCs. Cells were stimulated with 5 ng/mL IL-1α in ... 7. Cohen I, Rider P, Vornov E, Tomas M, Tudor C, Wegner M, Brondani L, Freudenberg M, Mittler G, Ferrando-May E, Dinarello CA, ...
Name: peroxisome proliferative activated receptor, gamma, coactivator 1 alpha. Synonyms: Pgc1, PPAR Gamma Coactivator-1, Pgco1 ... Name: NPC1 like intracellular cholesterol transporter 1. Synonyms: Niemann-Pick disease, type C1, 9130221N23Rik ... Name: prolyl 3-hydroxylase 2. Synonyms: Leprel1. Type: Gene. Species: Mus musculus (mouse) ... Synonyms: sialidase 1, lysosomal sialidase, G9, Bat-7, Neu-1, Map-2, Apl, Aglp, Bat7 ...
... cholesterol, high-density lipoprotein (HDL) cholesterol, and blood glucose levels. Venous blood samples (10 ml) were collected ... Prolyl-4-hydroxylase (C2, Santa Cruz) staining was used to be sure that isolated cells were HFs. ... Moreover, NPM is crucial for inflammatory gene expression induced by tumor necrosis factor alpha (TNF-α) and ... since they are contained either in small membranous vesicles or packaged within HDL-cholesterol or linked to RNA-binding ...
cholesterol 25-hydroxylase [Source:HGN.... CLDND1. 56650. CLDND1. claudin domain containing 1 [Source:HG.... ... TNF alpha induced protein 8 [Source:HG.... TNFAIP8L1. 126282. TNFAIP8L1. TNF alpha induced protein 8 like 1 [So.... ... show 7 additional gene sets from the source publication) GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_ ...
i Serum total cholesterol, HDL cholesterol, and LDL cholesterol levels. j Serum TG and FFA levels (n = 6-10/group for FFA). ... peroxisome proliferator-activated receptor alpha/gamma; PPARGC1A, PPARg coactivator-1 alpha; PRDM16, PR/SET domain-16; UCP1, ... Berra E, Benizri E, Ginouves A, Volmat V, Roux D, Pouyssegur J (2003) HIF prolyl-hydroxylase 2 is the key oxygen sensor setting ... h Serum total cholesterol, HDL cholesterol, and LDL cholesterol levels. i Serum TG and FFA levels (n = 6-9/group). Data are ...
Alfacalcidol is Vitamin D-hormone analog which is activated by the enzyme 25-hydroxylase in the liver for systemic and in ... Generic One-alpha Alfacalcidol is an active metabolite of Vitamin D, which performs important functions in regulation of the ... Taking melatonin leads to an average reduction in total cholesterol.. $ 0.48. Buy Now! ... Call your doctor if you are still constipated or irregular after using this medication for 7 days in a row.. Store at room ...
Regulation of testicular P-450 cholesterol side-chain cleavage and P-450 C17-20 lyase/C17 hydroxylase enzymes in the neonatal ... Ouabain and substrate affinities of human Na(+)-K(+)-ATPase alpha(1)beta(1), alpha(2)beta(1), and alpha(3)beta(1) when ... Thyroid hormone regulates alpha and alpha + isoforms of Na,K-ATPase during development in neonatal rat brain J Biol Chem. 1988 ... Differential regulation of Na,K-ATPase alpha 1, alpha 2, and beta subunit mRNA and protein levels by thyroid hormone J Biol ...