Differential activities of plant polyphenols on the binding and internalization of cholera toxin in vero cells. J. Biol. Chem. ...

Vajdy, M.; Lycke, N.Y. Cholera toxin adjuvant promotes long-term immunological memory in the gut mucosa to unrelated immunogens ... such as cholera toxin (CT) or E. coli enterotoxin (LT) (reviewed in [14]). The first scientific reports of exogenous adjuvants ... Well-established adjuvants such as the mucosally-delivered Cholera toxin are clearly able to promote long-term immunological ... Whether or not the mucosal adjuvant used for this vaccine (inactivated E.coli heat-labile toxin) was the culprit subsequently ...

Malley and coworkers tested killed, unencapsulated mutated Rx1 cells, applied intranasally with cholera toxin (CT) as an ... Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein. ... the alteration of the pneumolysin toxin gene that removes the proteins cytolytic and complement-activating activity [51,52]. ...

... cholerae releases cholera toxin (CT) [7]. Drugs, such as nicotinic acid, berberine sulfate, loperamide, and chlorpromazine, ... Bromelain acts as an antibacterial agent by inhibiting the growth of intestinal bacteria, such as Vibrio cholera and ... Several mechanisms inside cells protect their DNA from harmful genomic variability and toxins [9]. However, when cells lose ... Oral rehydration, however, does not hinder the secretion of toxins or alleviate diarrhea [129]. Scientists have demonstrated ...

In contrast to the case of β1 integrin, only two RTKs, EGFR and EphA2, were biotinylated when an HRP-conjugated cholera toxin B ...

... it is also known that different bacterial toxins (Shiga toxin and Cholera toxin) and certain viruses (Polyoma virus and simian ... As shown for US28, one potential strategy to target infected cells is the use of fusion toxin protein (FTP) to specifically ... Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus ... bacterial toxins and viruses (SV40, Polyoma viruses) can occur through caveolae [6]. Three types of caveolins (CAV 1, 2, 3) are ...

100 ng/mL cholera toxin, 10 μg/mL insulin and 50 IU penicillin/streptomycin in a humidified atmosphere with 5% CO2 at 37 °C. ...

Toxins, an international, peer-reviewed Open Access journal. ... Expression of Cholera Toxin (CT) and the Toxin Co-Regulated ... ICMR-National Institute of Cholera and Enteric Diseases, Kolkata 700010, India. Interests: Vibrio cholerae; cholera; cholera ... The Functions of Cholera Toxin Subunit B as a Modulator of Silica Nanoparticle Endocytosis by Eva Susnik ... Cholera toxin (CT) has been considered an important protein in several medical research and technology advancements. CT serves ...

Using the Pichia system, these toxins could be obtained in sufficient quantities (Vm24 1.6 mg/L, AnTx 46 mg/L, and Ts6 7.5 mg/L ... Tagged Vm24 and untagged AnTx are nearly equivalent to native toxins in blocking Kv1.3 (Kd = 4.4 pM and Kd = 0.72 nM, ... The approach described here provides a method that can be optimized for toxin production to develop more selective and ... extensive studies require amounts of toxin that cannot be readily obtained directly from venoms. The Pichia pastoris expression ...

Miller, J.F. Bacteriophage and the evolution of epidemic Cholera. Infect. Immun. 2003, 71, 2981-2982. [Google Scholar] [ ... toxin-antitoxin system and phage immunity; Brown, phage particle-associated proteins (PPAPs); Yellow, membrane/peptidoglycan ... toxin-antitoxin system and phage immunity; Brown, phage particle-associated proteins (PPAPs); Yellow, membrane/peptidoglycan ...

... such as in the John Snow cholera map of 1854. Research indicates that the earliest disease maps were found in Germany over 200 ... environmental public health concerns such as heat island effect as well as the reduction of UV radiation and airborne toxins on ...