Macrophages promote progression of spasmolytic polypeptide-expressing metaplasia after acute loss of parietal cells<...Macrophages promote progression of spasmolytic polypeptide-expressing metaplasia after acute loss of parietal cells<...

... through transdifferentiation of chief cells. In the presence of inflammation, SPEM can advance into a more proliferative ... To characterize SPEM in each model, gastric tissues were collected and levels of Cftr, Dmbt1, and Gpx2 mRNAs were measured. ... However, macrophage-depleted mice given L635 showed significant reductions in numbers of SPEM cells, SPEM cell proliferation, ... However, macrophage-depleted mice given L635 showed significant reductions in numbers of SPEM cells, SPEM cell proliferation, ...
more infohttps://yonsei.pure.elsevier.com/en/publications/macrophages-promote-progression-of-spasmolytic-polypeptide-expres

Gastric chief cell - WikipediaGastric chief cell - Wikipedia

A gastric chief cell (or peptic cell, or gastric zymogenic cell) is a type of cell in the stomach that releases pepsinogen and ... parathyroid chief cells). Chief cells are also known as peptic cells. Gastric acid Fundic glands Kitamura N, Tanimoto A, Hondo ... The terms chief cell and zymogenic cell are often used without the word "gastric" to name this type of cell. However those ... Gastric chief cells are generally located deep in the mucosal layer of the stomach lining. Chief cells release the zymogen ( ...
more infohttps://en.wikipedia.org/wiki/Gastric_chief_cell

Chief Cells, GastricChief Cells, Gastric

Chief cells synthesize and export an inactive enzyme PEPSINOGEN which is converted into the highly proteolytic enzyme PEPSIN in ... Epithelial cells that line the basal half of the GASTRIC GLANDS. ... Chief Cells, Gastric. Epithelial cells that line the basal half ... of the GASTRIC GLANDS. Chief cells synthesize and export an inactive enzyme PEPSINOGEN which is converted into the highly ...
more infohttp://atlas.centralx.com/p/image/cells/epithelial-cells/chief-cells-gastric/

Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium.  - PubMed - NCBIDifferentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium. - PubMed - NCBI

doi: 10.1016/j.cell.2013.09.008. Research Support, N.I.H., Extramural; Research Support, Non-U.S. Govt ... Troy(+) chief cells can be cultured to generate long-lived gastric organoids. Troy marks a specific subset of chief cells that ... chief cell arrays with a chief cell array prepared from laser-captured chief cells, while pit and parietal cell arrays cluster ... Edu: proliferative cells; cell borders marked by E-cadherin. (F) Dividing (Ki67 positive) chief cells (gastric intrinsic factor ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/24120136?dopt=Abstract

Gastric Secretions Flashcards by georgia hale | BrainscapeGastric Secretions Flashcards by georgia hale | Brainscape

Entero-chromaffin like cells which are always close to parietal cells. Secrete histamine which is a trigger for gastric acid ... Ach acting directly on the parietal cells causing H+ secretion.. - ACh acting on the G cells that produce gastrin, which acts ... Role of chief cells. Secrete pepsinogen, precursor of the active pepsin which breaks down proteins ... How many parietal cells are in the human stomach and what is the concentration of the acid they produce? ...
more infohttps://www.brainscape.com/flashcards/gastric-secretions-6858521/packs/10782136

Gastric gland, TEM - Stock Image - C015/1025 - Science Photo LibraryGastric gland, TEM - Stock Image - C015/1025 - Science Photo Library

... showing several enzyme-secreting chief cells with many secretory granules, and a single parietal cell, which produces stomach ... Transmission electron micrograph (TEM) of a section through the deep region of a gastric (fundus) gland, ... Gastric glands are found in the body, the gastric mucosa, and fundus of the stomach. Chief cells secrete pepsinogen. Acid ... showing several enzyme-secreting chief cells with many secretory granules, and a single parietal cell, which produces stomach ...
more infohttps://www.sciencephoto.com/media/495194/view

Digestive System Flashcards by Lauren Bell | BrainscapeDigestive System Flashcards by Lauren Bell | Brainscape

contains 3 types of secretory cells. -mucous cell. -chief cells. -parietal cells ... Gastric Juice- Gastric Glands. what kind of cells does it contain? what are the 3 types? ... moves food w/ gastric juice (mix w/ food to break down). initiates digestion of proteins. carries on limited absorption. bolus ... absorptive cells w/ enzymes in them. Function: increase surface area of intestine for absorption. -contains blood & lymph ...
more infohttps://www.brainscape.com/flashcards/digestive-system-5075721/packs/6163410

List of subjects in Grays Anatomy: XI. SplanchnologyList of subjects in Gray's Anatomy: XI. Splanchnology

Gastric glands * chief cells or central cells * parietal cells or oxyntic cells ... Macula densa • Juxtaglomerular cells • Extraglomerular mesangial cell. Filtration. Glomerular basement membrane • Podocyte • ... Urethra , Testes , Scrotum , Spermatic cord , Epididymis , Seminiferous tubules , Sertoli cell , Rete testis , Efferent ducts ... Urethra , Testes , Scrotum , Spermatic cord , Epididymis , Seminiferous tubules , Sertoli cell , Rete testis , Efferent ducts ...
more infohttps://www.bionity.com/en/encyclopedia/List_of_subjects_in_Gray%27s_Anatomy%3A_XI._Splanchnology.html

Chief cell - WikipediaChief cell - Wikipedia

... there are three types of chief cells, the gastric chief cell, the parathyroid chief cell, and the type 1 chief cells found in ... Cell types[edit]. The gastric chief cell (also known as a zymogenic cell or peptic cell) is a cell in the stomach that releases ... Gastric chief cells are epithelial cells which are found within the gastric unit or gastric gland, and form the base of the ... Parietal cells may secrete factors that lead to transdifferentiation of chief cells, so if lost, chief cells do not normally ...
more infohttps://en.wikipedia.org/wiki/Chief_cell

Changes of telomere length with aging - Takubo - 2010 - Geriatrics & Gerontology International - Wiley Online LibraryChanges of telomere length with aging - Takubo - 2010 - Geriatrics & Gerontology International - Wiley Online Library

Basal cells , fibroblasts , prickle cells. Gastric mucosa (Aida et al. 2007). Fibroblasts , chief cells, parietal cells , neck ... Gastric mucosa. Through the measurement of cell types in the gastric mucosa, we were able to show that progressively shorter ... Fibroblasts , basal cells , parabasal cells , prickle cells. Esophageal mucosa (Kammori et al. 2006). ... The spleen consists of lymphocytes, endothelial cells, reticular cells and some other cells. Reduction of telomere length might ...
more infohttp://onlinelibrary.wiley.com/doi/10.1111/j.1447-0594.2010.00605.x/full

Free Anatomy Flashcards about StomachFree Anatomy Flashcards about Stomach

Chief Cells. Secretes pepsinogen, gastric lipase and intrinsic factor; Created by: 100000434525601 ... 1) Mixes Saliva, food, and gastric juices = chyme 2) Reservoir for food 3) Gastric juic secretion with HCL, pepsin, intrinsic ... Parietal Cells. HCL secretion --, kills microbes in food; denatures proteins; turns pepsinogen into pepsin. ... Surface Mucous Cells. Secrete mucus; form protective barrier that prevents digestion of stomach. ...
more infohttps://www.studystack.com/flashcard-1292363

Helicobacter pylori Induces Plasminogen Activator Inhibitor 2 in Gastric Epithelial Cells through Nuclear Factor-κB and RhoA |...Helicobacter pylori Induces Plasminogen Activator Inhibitor 2 in Gastric Epithelial Cells through Nuclear Factor-κB and RhoA |...

PAI-2 was expressed mainly in chief and mucous cells. In a gastric cancer cell line (AGS), H. pylori increased PAI-2 expression ... by Helicobacter pylori in human gastric epithelial cells: role in epithelial cell migration. J. Cell Sci., 116: 3017-3026, 2003 ... A, AGS cells transfected with PAI-2-luc were cocultured with either AGS cells or human gastric glands on 0.2-μm pore Transwell ... Cell and Tumor Biology Helicobacter pylori Induces Plasminogen Activator Inhibitor 2 in Gastric Epithelial Cells through ...
more infohttp://cancerres.aacrjournals.org/content/64/5/1695

Bioline International Official Site (site up-dated regularly)Bioline International Official Site (site up-dated regularly)

PAR-2 modulates pepsinogen secretion from gastric-isolated chief cells. Am J Physiol 285: G611-G620. ... Activation of PAR-1 appears to be cytoprotective in a gastric epithelial cell line (Toyoda et al. 2003) and in a rat model ( ... Expression and cytoprotective effect of protease-activated receptor-1 in gastric epithelial cells. Scand J Gastroenterol 38: ... cell types. Finally, PARs and their ability to promote epithelial cell proliferation are discussed in terms of colon cancer. ...
more infohttp://www.bioline.org.br/request?oc05053

Digestive enzyme - WikipediaDigestive enzyme - Wikipedia

Parietal cells: Produce hydrochloric acid and intrinsic factor.. *Gastric chief cells: Produce pepsinogen. Chief cells are ... Gastric lipase: Gastric lipase is an acidic lipase secreted by the gastric chief cells in the fundic mucosa in the stomach. It ... Pepsin is the main gastric enzyme. It is produced by the stomach cells called "chief cells" in its inactive form pepsinogen, ... Gastric inhibitory peptide (GIP): This peptide decreases gastric motility and is produced by duodenal mucosal cells. ...
more infohttps://en.wikipedia.org/wiki/Digestive_enzyme

Zinselmeyer B[au] - PubMed - NCBIZinselmeyer B[au] - PubMed - NCBI

The gastric epithelial progenitor cell niche and differentiation of the zymogenic (chief) cell lineage. ... Tuning T Cell Signaling Sensitivity Alters the Behavior of CD4+ T Cells during an Immune Response. ... Malaria impairs T cell clustering and immune priming despite normal signal 1 from dendritic cells. ... Cell. 2015 Mar 12;160(6):1061-71. doi: 10.1016/j.cell.2015.01.049. Epub 2015 Feb 26. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Zinselmeyer+B%5Bau%5D&dispmax=50

Free Science Flashcards about Animal Sci VocabFree Science Flashcards about Animal Sci Vocab

Enzyme precursor secreted by the chief cells in the stomach. Hydrochloric Acid. HCl; normal part of gastric juice in cats and ... Protein-degrading enzyme that is activated from pepsinogen in the stomach; the principal digestive component of gastric juice. ... complex, gel-like substance secreted by specific cells or mucous glands; acts as a protective barrier and lubricant. ... Area on the free surface of an epithelial cell that is covered with microvilli. ...
more infohttps://www.studystack.com/flashcard-574907

protein facts, information, pictures | Encyclopedia.com articles about proteinprotein facts, information, pictures | Encyclopedia.com articles about protein

Proteins allow cells to detect and react to hormones and toxins in their surroundings, and as the chief ingredient in ... by the parietal cells located in the gastric mucosa of the GI (gastrointestinal ) tract. Hydrochloric acid provides for a very ... Molecular Cell Biology, 4th ed. New York: W. H. Freeman, 2000.. Sadava, David E. Cell Biology: Organelle Structure and Function ... These chains of hemoglobin precipitate in the cell, causing the red blood cells to assume a sickle shape. All of these ...
more infohttps://www.encyclopedia.com/science-and-technology/biochemistry/biochemistry/protein

Exocrine gland - wikidocExocrine gland - wikidoc

gastric chief cell, Wasmanns glands. stomach. serous. - glomus coccygeum, coccygeal gland, Luschkas gland or ganglion. coccyx ... Examples include chief cells and Paneth cells. *Mucous cells secrete mucus. Examples include Brunners glands, esophageal ... Merocrine glands - cells secrete their substances by exocytosis. Also called "eccrine.". Product secreted. *Serous cells ... goblet cells. digestive tract, respiratory tract. mucous. simple unicellular Henles glands. eyelids, in the conjuctiva. -. ...
more infohttp://wikidoc.org/index.php/Exocrine_gland

New Report Counters Claims on the Origin of Gastric Cancer | The Scientist Magazine®New Report Counters Claims on the Origin of Gastric Cancer | The Scientist Magazine®

... cells in the stomach revert to stem cells and lead to cancer, but new results do not observe such dedifferentiation. ... M. Hata et al., "GPR30-expressing gastric chief cells do not dedifferentiate but are eliminated via PDK-dependent cell ... conclusions depend largely on the assertion that GRP30 labels all chief cells and only chief cells, which he does not think has ... Regardless of whether the chief cell hypothesis turns out to be true, the question of how SPEM gives rise to gastric cancer ...
more infohttps://www.the-scientist.com/news-opinion/new-report-counters-claims-on-the-origin-of-gastric-cancer-67094

Neurosecretory cell | definition of neurosecretory cell by Medical dictionaryNeurosecretory cell | definition of neurosecretory cell by Medical dictionary

What is neurosecretory cell? Meaning of neurosecretory cell medical term. What does neurosecretory cell mean? ... Looking for online definition of neurosecretory cell in the Medical Dictionary? neurosecretory cell explanation free. ... chief cells 1. columnar or cuboidal epithelial cells that line the lower portions of the gastric glands and secrete pepsin. ... See also betz cells, gauchers cells, golgis cells, hela cells, hürthle cell, kupffers cells, merkel cell, mesangial cell, ...
more infohttps://medical-dictionary.thefreedictionary.com/neurosecretory+cell

Segmented cell | definition of segmented cell by Medical dictionarySegmented cell | definition of segmented cell by Medical dictionary

... segmented cell explanation free. What is segmented cell? Meaning of segmented cell medical term. What does segmented cell mean? ... Looking for online definition of segmented cell in the Medical Dictionary? ... chalice cell. Goblet cell.. chemoreceptor cell. Chemoreceptor.. chief cell. 1. Any of the cells of the parathyroid gland that ... oxyntic cell. A parietal cell of the gastric glands; it produces hydrochloric acid and the intrinsic factor. ...
more infohttps://medical-dictionary.thefreedictionary.com/segmented+cell

Expression of Wnt-5a Is Correlated with Aggressiveness of Gastric Cancer by Stimulating Cell Migration and Invasion | Cancer...Expression of Wnt-5a Is Correlated with Aggressiveness of Gastric Cancer by Stimulating Cell Migration and Invasion | Cancer...

We also found that Wnt-5a is expressed in Chief cells in normal gastric mucosa. It is generally believed that stem cells are ... Actions of Wnt-5a on cell growth and migration of gastric cancer cells. Comparison of various gastric cancer cell lines ... Cell, Tumor, and Stem Cell Biology Expression of Wnt-5a Is Correlated with Aggressiveness of Gastric Cancer by Stimulating Cell ... and then cell numbers were counted. B, stimulation of cell migration by Wnt-5a. a, the indicated gastric cells were placed in ...
more infohttp://cancerres.aacrjournals.org/content/66/21/10439

Digestive Enzymes - The Hidden Dangers | John Douillards LifeSpaDigestive Enzymes - The Hidden Dangers | John Douillard's LifeSpa

For example the chief cells in your stomach produce the enzyme called pepsin. They also make the enzyme gastric lipase. The ... Every cell in the body produces enzymes for various metabolic functions and most are anabolic, not catabolic (digestive), but ... Dr John, I have thought for years the increase of intestinal and gastric problems is related to the use of phages. Since 2005 ... Step 6 says to consider regular detoxification of liver and fat cells…by this do you mean repeating steps 1 to 6, (Decongesting ...
more infohttp://lifespa.com/digestive-enzymes-the-hidden-dangers/

Visible Human, Coronal Section/Anterior ThoraxVisible Human, Coronal Section/Anterior Thorax

Chief cells, located at the bottom of the gastric pits, secrete enzymes important in the breakdown of foodstuffs. Click on the ... and is organized into units called gastric pits. Parietal cells secrete HCl while neck and surface mucus cells secrete mucus to ... An epithlielium lines the interior of the stomach (gastric epithelium). This epithelium contains many cell types, ... In the lungs red blood cells exchange carbon dioxide for oxygen. mesentary: The mesentaries connect the intestines and internal ...
more infohttp://www.madsci.org/cgi-bin/cgiwrap/~lynn/image?return=&name=a_vmY1649&show_all=1&search=

Reference.com - Whats Your QuestionReference.com - What's Your Question

Pepsinogen is secreted by chief cells in the gastric glands of the body and antrum of the stomach. ... en.wikipedia.org/wiki/Gastric_acid. Gastric acid, gastric juice, or stomach acid, is a digestive fluid formed in the stomach ... The role of hydrochloric acid in the stomach, along with the other gastric juices, is to break down foods and cause the release ... Hydrochloric acid (also known as stomach acid) is the main component of gastric juices produced in the stomach. It is the only ...
more infohttps://www.reference.com/web?q=function+of+hcl+in+digestion&qo=contentPageRelatedSearch&o=600605&l=dir