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*  Human Metabolome Database: Showing metabocard for Chenodeoxycholic acid glycine conjugate (HMDB0000637)
Chenodeoxycholic acid glycine conjugate is an acyl glycine and a bile acid-glycine conugate. It is a secondary bile acid ... The major components of bile are cholic acid and chenodeoxycholic acid. In a first step the bile acids are converted to an acyl ... Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid. ... In hepatocytes, both primary and secondary bile acids undergo amino acid conjugation at the C-24 carboxylic acid on the side ...
http://www.hmdb.ca/metabolites/HMDB0000637
*  Effect of ursodeoxycholic acid on the kinetics of cholic acid and chenodeoxycholic acid in patients with primary sclerosing...
If you are a society or association member and require assistance with obtaining online access instructions please contact our Journal Customer Services team ...
http://onlinelibrary.wiley.com/doi/10.1002/hep.1840170614/pdf
*  Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis |...
Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis. H M ... Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis ... Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis ... Cyclosporin A blocks bile acid synthesis in cultured hepatocytes by specific inhibition of chenodeoxycholic acid synthesis ...
http://www.biochemj.org/content/275/2/501
*  Glycocholic Acid Summary Report | CureHunter
The glycine conjugate of CHOLIC ACID. It acts as a detergent to solubilize fats for absorption and is itself absorbed. ... Technetium Tc 99m Diethyl-iminodiacetic Acid 4. Aminopyrine (Aminophenazone) 5. Sodium 6. Chenodeoxycholic Acid (Chenix) ... Bile Acids and Salts: 3397*Cholic Acids: 8*Glycocholic Acid: 105*Glycodeoxycholic Acid: 68 ... Glycocholic Acid. Subscribe to New Research on Glycocholic Acid The glycine conjugate of CHOLIC ACID. It acts as a detergent to ...
http://www.curehunter.com/public/keywordSummaryD006000-Glycocholic-Acid.do
*  Cerebrotendinous Xanthomatosis | Springer for Research & Development
Berginer VM, Salen G, Sheffer S (1984) Long-term treatment of cerebrotendinous xanthomatosis with chenodeoxycholic acid. N Engl ... effect of treatment with chenodeoxycholic acid. Hepatology 7: 266-271PubMedCrossRefGoogle Scholar ... 1976) A 25-hydroxylation pathway of cholic acid biosynthesis in man and rat. J Clin Invest 57: 897-903PubMedCrossRefGoogle ... 1985) Biosynthesis of bile acids in cerebrotendinous xanthomatosis. J Clin Invest 76: 744-751PubMedCrossRefGoogle Scholar ...
https://rd.springer.com/chapter/10.1007/978-3-662-02568-0_21
*  KEGG PATHWAY: Secondary bile acid biosynthesis - Brucella melitensis ATCC 23457
... formed from the 7alpha-dehydroxylation of cholic acid and chenodeoxycholic acid, respectively. ... The secondary bile acids in humans include deoxycholic acid and lithocholic acid, ... The secondary bile acids are derived from the primary bile acids by the enzymatic action of intestinal bacteria through the ... Secondary bile acid biosynthesis - Brucella melitensis ATCC 23457 [ Pathway menu , Organism menu , Pathway entry , Download ...
http://www.genome.jp/kegg-bin/show_pathway?bmi00121
*  Ursodeoxycholic acid attenuates colonic epithelial secretory function.
Dihydroxy bile acids, such as chenodeoxycholic acid (CDCA), are well known to promote colonic fluid and electrolyte secretion, ... However, CDCA is rapidly metabolised by colonic bacteria to ursodeoxycholic acid (UDCA), the effects of which on epithelial ... Ursodeoxycholic acid attenuates colonic epithelial secretory function., Journal of Physiology, 2013, 2307 2318 ... an effect we hypothesised to be due to bacterial metabolism of UDCA to lithocholic acid (LCA). Accordingly, LCA (50-200 μm) ...
http://www.tara.tcd.ie/handle/2262/72992
*  Genetic Defects in Synthesis and Transport of Bile Acids | Pediatric Endocrinology and Inborn Errors of Metabolism, 2e |...
The major primary bile acids in mammals are cholic acid and chenodeoxycholic acid, the structures of which are shown in Figure ... This loss of bile acids is compensated for by de novo synthesis of bile acids in the liver. Bile acids synthesized in the liver ... Synthesis of Bile Acids. ++. Conversion of cholesterol into bile acids illustrates the high capacity of the liver to convert ... The size of the normal bile acid pool in adults is about 2 to 4 g, and this represents the total bile acid content in the liver ...
http://accesspediatrics.mhmedical.com/content.aspx?bookid=2042§ionid=154112839
*  Ursodeoxycholic acid and cholesterol induce enterohepatic cycling of " by Sanchez N. Mendez, M A. Brink et al.
METHODS: Male inbred C57L/J mice and Sprague-Dawley rats were fed low doses of UDCA, chenodeoxycholic acid (CDCA), or ... Dietary cholesterol and bile acids, particularly UDCA, increased cecal bile salt levels, unconjugated bilirubin and ... the former by competition for and the latter by down-regulation of ileal bile acid transporters. Because ileectomy in rats ... Oral administration of ursodeoxycholic acid (UDCA) and cholesterol causes bile salt malabsorption; ...
https://mouseion.jax.org/stfb1990_1999/1114/
*  The role of 11β-hydroxysteroid dehydrogenase type 1 in bile acid homeostasis - edoc
We found that human 11β-HSD1 reduces the secondary BA 7-oxolithocholic acid (7-oxoLCA) mainly to chenodeoxycholic acid (CDCA) ... Bile acids (BAs) are important modulators of metabolic functions such as lipid, triglyceride and glucose homeostasis. ... The role of 11β-hydroxysteroid dehydrogenase type 1 in bile acid homeostasis. 2013, PhD Thesis, University of Basel, Faculty of ... The role of 11β-hydroxysteroid dehydrogenase type 1 in bile acid homeostasis ...
http://edoc.unibas.ch/29887/
*  Serum bile acid profiling reflects enterohepatic detoxification state and intestinal barrier function in inflammatory bowel...
Finally, we found that in ileocecal resected CD patients, the unconjugated primary BAs, cholic acid and chenodeoxycholic acid, ... Finally, we found that in ileocecal resected CD patients, the unconjugated primary BAs, cholic acid and chenodeoxycholic acid, ... taurocholic acid, and glycochenodeoxycholic acid were as significantly increased as the secondary BAs LCA, ursodeoxycholic acid ... taurocholic acid, and glycochenodeoxycholic acid were as significantly increased as the secondary BAs LCA, ursodeoxycholic acid ...
http://www.zora.uzh.ch/id/eprint/32468/
*  chenodeoxycholic acid (CHEBI:16755)
... is a bile acid (CHEBI:3098) chenodeoxycholic acid (CHEBI:16755) is a C24-steroid (CHEBI: ... chenodeoxycholic acid (CHEBI:16755) is a dihydroxy-5β-cholanic acid (CHEBI:23775) chenodeoxycholic acid (CHEBI:16755) is ... chenodeoxycholic acid (CHEBI:16755). obeticholic acid (CHEBI:43602) has functional parent chenodeoxycholic acid (CHEBI:16755). ... chenodeoxycholic acid (CHEBI:16755) has role human metabolite (CHEBI:77746) chenodeoxycholic acid (CHEBI:16755) has role mouse ...
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:16755
*  Chenodeoxycholic acid (Chenodal) Use During Pregnancy
Advice and warnings for the use of Chenodeoxycholic acid (Chenodal) during pregnancy. FDA Pregnancy Category X - Not for use in ... Chenodeoxycholic acid Pregnancy and Breastfeeding Warnings. Chenodeoxycholic acid is also known as: Chenodal ... Chenodeoxycholic acid Breastfeeding Warnings. A decision should be made to discontinue breastfeeding or discontinue the drug, ... Chenodal (chenodeoxycholic acid)." Manchester Pharmaceutical, Fort Collins, CO. *EMEA. European Medicines Agency "EPARs. ...
https://www.drugs.com/pregnancy/chenodeoxycholic-acid.html
*  Chenodeoxycholic acid - DrugBank
... is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by ... It can also reduce the amount of other bile acids that can be harmful to liver cells when levels are elevated. ... Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid ... Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of ...
https://www.drugbank.ca/drugs/DB06777
*  Chenodeoxycholic acid and mipomersen Drug Interactions - Drugs.com
A Major Drug Interaction exists between chenodeoxycholic acid and mipomersen. View detailed information regarding this drug ... and using it with other medications that can also affect the liver such as chenodeoxycholic acid may increase that risk. You ... chenodeoxycholic acid mipomersen. Applies to: chenodeoxycholic acid and mipomersen. Mipomersen may cause liver problems, ...
https://www.drugs.com/drug-interactions/chenodeoxycholic-acid-with-mipomersen-3212-0-3451-0.html
*  Chenodeoxycholic Acid and Ursodeoxycholic Acid | Springer for Research & Development
Tint, G. S., Salen, G., and Shefer, S.: Effect of ursodeoxycholic acid and chenodeoxycholic acid on cholesterol and bile acid ... Ursodeoxycholic acid versus chenodeoxycholic acid. Comparison of their effects on bile acid and bile lipid composition in ... Fedorowski, T., Salen, G., Tint, G. S., and Mosbach, E.: Transformation of chenodeoxycholic acid and ursodeoxycholic acid by ... Maxwell R.A., Eckhardt S.B. (1990) Chenodeoxycholic Acid and Ursodeoxycholic Acid. In: Drug Discovery. Humana Press, Totowa, NJ ...
https://rd.springer.com/chapter/10.1007/978-1-4612-0469-5_28
*  Chenodeoxycholic acid - Wikipedia
Some other mammals have muricholic acid or deoxycholic acid rather than chenodeoxycholic acid. Chenodeoxycholic acid is ... Chenodeoxycholic acid (also known as chenodesoxycholic acid, chenocholic acid and 3α,7α-dihydroxy-5β-cholan-24-oic acid) is a ... Chenodeoxycholic acid has been used as medical therapy to dissolve gallstones. Chenodeoxycholic acid can be used in the ... Salts of this carboxylic acid are called chenodeoxycholates. Chenodeoxycholic acid is one of the main bile acids produced by ...
https://en.wikipedia.org/wiki/Chenodeoxycholic_acid
*  Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver...
Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver ... Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver ...
http://onlinelibrary.wiley.com/doi/10.1002/hep.22712/suppinfo
*  Adjunct to bile-acid treatment for gall-stone dissolution: low-dose chenodeoxycholic acid combined with a terpene preparation. ...
Adjunct to bile-acid.... *Adjunct to bile-acid treatment for gall-stone dissolution: low-dose chenodeoxycholic acid combined ... Adjunct to bile-acid treatment for gall-stone dissolution: low-dose chenodeoxycholic acid combined with a terpene preparation. ... Adjunct to bile-acid treatment for gall-stone dissolution: low-dose chenodeoxycholic acid combined with a terpene preparation. ... Adjunct to bile-acid treatment for gall-stone dissolution: low-dose chenodeoxycholic acid combined with a terpene preparation. ...
http://www.bmj.com/content/282/6264/611.2
*  Chenodiol (Chenodeoxycholic Acid) for Dissolution of Gallstones: The National Cooperative Gallstone StudyA Controlled Trial of...
Chenodiol (Chenodeoxycholic Acid) for Dissolution of Gallstones: The National Cooperative Gallstone Study: A Controlled Trial ... Chenodiol (Chenodeoxycholic Acid) for Dissolution of Gallstones: The National Cooperative Gallstone Study: A Controlled Trial ... A double-masked study was conducted to determine the efficacy and safety of randomly allocated chenodiol (chenodeoxycholic acid ...
http://annals.org/aim/article-abstract/695044/chenodiol-chenodeoxycholic-acid-dissolution-gallstones-national-cooperative-gallstone-study-controlled
*  Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - Calbiochem CAS 2646-38-0 | 220411
Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability ... Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - Calbiochem. 220411 , Chenodeoxycholic Acid, Sodium Salt - CAS 2646-38-0 - ... Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability ... Bile acid that has been shown to increase intracellular Ca2+ in isolated rat hepatocyte couplets. Induces a permeability ...
http://www.emdmillipore.com/US/en/product/Chenodeoxycholic-Acid-Sodium-Salt-CAS-2646-38-0-Calbiochem,EMD_BIO-220411
*  Combination therapy with oral ursodeoxycholic and chenodeoxycholic acids: pretreatment computed tomography of the gall bladder...
Combination therapy with oral ursodeoxycholic and chenodeoxycholic acids: pretreatment computed tomography of the gall bladder ... Combination therapy with oral ursodeoxycholic and chenodeoxycholic acids: pretreatment computed tomography of the gall bladder ... 55 patients with radiolucent gall stones were treated with the combination of 7.5 mg chenodeoxycholic acid (CDCA) and 5.0 mg ... Side effects were few but four patients could not tolerate the prescribed bile acids because of diarrhoea or nausea. Analysis ...
http://gut.bmj.com/content/33/3/375
*  buy Chenodeoxycholic acid
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http://biomaterials-2011-dfg-nsf-conference.com/tag/buy-chenodeoxycholic-acid/
*  Gentaur Molecular :BioBasic \ Chenodeoxycholic acid free acid \ CN1185
Chenodeoxycholic acid free acid \ CN1185 for more molecular products just contact us ... We have also other products like : Chenodeoxycholic acid free acid Related products : Chenodeoxycholic acid free acid ... amino acid conjugation of benzoic acid. WP1307: Fatty Acid Beta Oxidation. WP1311: Folic Acid Network. WP133: Fatty Acid Omega ... amino acid conjugation of benzoic acid. WP1020: Fatty Acid Biosynthesis. WP105: Fatty Acid Beta Oxidation 2. WP1061: Fatty Acid ...
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*  Rabbit bile powder containing chenodeoxycholic acid
In the detection of amino acids, in addition to aspartic acid, glutamic acid, valine, leucine, tyrosine several amino acid bear ... the total bile acid content was determined by the amount of bile acid, the bile acid content of rabbit bile. The total bile ... The results showed that the bile powder was mainly composed of bilecholate and chenodeoxycholic acid. The content of total bile ... Yourlocation: Home > News > Rabbit bile powder containing chenodeoxycholic acid Through the identification of rabbit bile ...
http://www.nwsbio.com/news/Rabbit-bile-powder-containing-chenodeoxycholic-acid-179.html