Chemokine CXCL5. Quimiocina CXCL5. Quimiocina CXCL6. Chemokine CXCL6. Quimiocina CXCL6. Quimiocina CXCL9. Chemokine CXCL9. ...
Chemokine CXCL12. *Chemokine CXCL13. *Chemokine CXCL16. *Chemokine CXCL2. *Chemokine CXCL5. *Chemokine CXCL6 ... A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as ...
A recombinant version of human CNTF (rhCNTF), trade name Axokine, is a modified version with a 15 amino acid truncation of the C-terminus and two amino acid substitutions. It is three to five times more potent than CNTF in in vitro and in vivo assays and has improved stability properties.[6] Like CNTF it is a neurotrophic factor, and may stimulate nerve cells to survive. It was tested in the 1990s as a treatment for amyotrophic lateral sclerosis. It did not improve muscle control as much as expected, but trial participants did report a loss of appetite. Phase III clinical trials for the drug against obesity were conducted in 2003 by Axokines maker, Regeneron, demonstrating a small positive effect in some patients, but the drug was not commercialized. A major problem with the treatment was that in nearly 70% of the subjects tested, antibodies against Axokine were produced after approximately three months of treatment.[7] In the minority of subjects who did not develop the antibodies, weight loss ...
Interleukins are a group of cytokines (secreted signaling molecules) that were first seen to be expressed by white blood cells (leukocytes, hence the -leukin) as a means of communication (inter-). The name is something of a relic though (the term was coined by Dr. Paetkau, University of Victoria); it has since been found that interleukins are produced by a wide variety of bodily cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. ...
In a study of the blocking of interferon (IFN) by the Japanese Encephalitis Virus (JEV), a group of researchers infected human recombinant IFN-alpha with JEV, DEN-2, and PL406, which are all viruses, and found that some viruses have manifested methods that give them a way around the IFN-alpha/beta response. The viruses need to master these methods so they can have the ability to carry on viral replication and production of new viruses.[4] The ways that viruses find a way around the IFN response is through the inhibition of interferon signaling, production, and the blocking of the functions of IFN-induced proteins.[4] It is not unusual to find viruses encoding for a multiple number of mechanisms to allow them to elude the IFN response at many different levels.[4] While doing the study with JEV, Lin and his coworkers found that with IFN-alphas inability to block JEV means that JEV may be able to block IFN-alpha signaling which in turn would prevent IFN from having STAT1, STAT2, ISGF3, and IRF-9 ...
CXCL6, GCSF, G-CSF R / CD 114, GDF1, GDF11, GDF-15, GDF3, GDF5, GDF8, GDF9, GDNF, Gelsolin, GFR alpha-1, GFR alpha-2, GFR alpha ... CXCL6), GCSF, G-CSFR(CD114), GCSH , GDA, GDF1, GDF11, GDF-15, GDF3, GDF5, GDF7, GDF8, GDF9, GDI1, GDI2, GDNF, Gelsolin, ... Chemokine Arrays. * - Cytokine Arrays - Human. * - Cytokine Arrays - Mouse. * - Inflammation Arrays. * - Interleukin Arrays ...
20 interacting genes: ADRA1A CDK1 CLDND1 CXCL1 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCR2 FATE1 GNA14 GNA15 GNAI2 IGFBP5 PDCD6IP PPBP ... C-C Chemokine Receptor Activity. *C-C Chemokine Binding. *Interleukin-8 Binding ...
CXCL6.CXCL8.CXCL9.CXCR1.CXCR2.CXCR3.CXCR4.CXCR5.CXCR6.CYP2E1.CYSTM1.DDAH2.DDIT3.DDOST.DDX5.DDX58.DEFA4.DEFB103A/B.DERL1.DHX58. ... Chemokine Signaling. BCR Signaling. Angiotensin System. Virus-Host Interaction. DNA Sensing. Cytoxicity. Complement System. ...
32 interacting genes: CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CELF1 CMTM6 COPG1 COPS7A COX17 CTSG CXCL10 CXCL11 CXCL12 CXCL14 CXCL6 ... Chemokine Activity. *Growth Factor Activity. *CXCR Chemokine Receptor Binding. *Translation Repressor Activity, MRNA Regulatory ...
... is a potent chemokine that regulates the growth and motility of many cell types, such as vascular smooth muscle cells [77]. ... CXCL6, and neuropilin 1 in tumors from patients with rectal cancer," Cancer Research, vol. 69, no. 20, pp. 7905-7910, 2009. ...
20 interacting genes: ADRA1A CDK1 CLDND1 CXCL1 CXCL2 CXCL3 CXCL5 CXCL6 CXCL8 CXCR2 FATE1 GNA14 GNA15 GNAI2 IGFBP5 PDCD6IP PPBP ... C-C Chemokine Receptor Activity. *C-C Chemokine Binding. *Interleukin-8 Binding ...
CXCL6.CXCL8.CXCL9.CXCR3.CXCR4.CXCR5.CXCR6.CYBB.DAP3.DDIT4.DECR1.DGLUCY.DHFR2.DHRS4.DIABLO.DLL1.DOCK2.DUSP1.DVL2.EBI3.EGF.EGR1. ... Chemokine Signaling, Costimulatory Molecules, Interleukin Signaling, TCR signaling, JAK-STAT, MAPK and PI3K Signaling, Myc ... Downstream of the TCR, multiple pathways induce transcriptional changes that lead to the production of chemokines and cytokines ... Toxicity is correlated with certain cytokine and chemokine profiles. These signals can induce a pro-inflammatory environment in ...
Rat CXCL16(Chemokine C-X-C-Motif Ligand 16) ELISA Kit. *Rat CXCR3(Chemokine C-X-C-Motif Receptor 3) ELISA Kit ... Human CXCL6/GCP2 ELISA kit (4Ã-96T). LF-EK50760 Abfrontier 4Ã-96T. 2641.2 EUR ...