This review summarizes the versatile chemical modification methods that can be used to design GC-based drug carriers and ... and the versatility in chemical modifications enables production of a wide range of GC-based drug carriers. ... The reactive functional groups such as the amine and hydroxyl groups on the GC backbone allow for easy chemical modification ... with various chemical compounds (e.g., hydrophobic molecules, crosslinkers, and acid-sensitive and labile molecules), ...
... and to emphasize their genetic clusters and chemical structures as well as their bioactivities, ecological roles and ... due to their interesting bioactivities and for their potential to be prospective candidates in the development of drugs. It is ... Drugs 2015, 13, 6910-6946. AMA Style. Martins J, Vasconcelos V. Cyanobactins from Cyanobacteria: Current Genetic and Chemical ... Drugs, EISSN 1660-3397, Published by MDPI Disclaimer The statements, opinions and data contained in the journal Marine Drugs ...
These results emphasize that marine sponges are a prolific resource for novel bioactive actinomycetes with potential for drug ... Drugs 2013, 11, 1071-1086. [Google Scholar] [CrossRef]. *Forner, D.; Berrue, F.; Correa, H.; Duncan, K.; Kerr, R.G. Chemical ... Thomas, T.R.A.; Kavlekar, D.P.; LokaBharathi, P.A. Marine drugs from sponge-microbe association-A Review. Mar. Drugs 2010, 8, ... Drugs 2010, 8, 373-380. [Google Scholar] [CrossRef]. *Blunt, J.W.; Copp, B.R.; Keyzers, R.A.; Munro, M.H.; Prinsep, M.R. Marine ...
The chemical diversity varied substantially between the two temperatures for the tested species, ranging from 31% similarity ... The chemical diversity was generally highest at the lowest temperature. ... Drugs 2013, 11, 4232-4245. AMA Style. Huseby S, Degerlund M, Eriksen GK, Ingebrigtsen RA, Eilertsen HC, Hansen E. Chemical ... Drugs 2013, 11(11), 4232-4245; doi:10.3390/md11114232. Chemical Diversity as a Function of Temperature in Six Northern Diatom ...
From Drug Target to Leads-Sketching a Physico-Chemical Pathway for Lead Molecule Design In Silico. Pp. 324-360 (37) ... drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, ... Indexed in: Book Citation Index, Science (BKCI-S), Web of Science, BIOSIS Previews, EMBASE, Chemical Abstracts, EBSCO, Ulrichs ... Computer aided drug discovery, In silico lead design, Binding affinity and specificity, ADMET. ...
Large-Scale Prediction of Drug Targets Based on Local and Global Consistency of Chemical-Chemical Networks. Author(s): Guohua ... Keywords: Drug target, chemical-chemical interaction, semi-supervised learning, leave-one-out cross validation, guilt by ... Keywords:Drug target, chemical-chemical interaction, semi-supervised learning, leave-one-out cross validation, guilt by ... Title:Large-Scale Prediction of Drug Targets Based on Local and Global Consistency of Chemical-Chemical Networks ...
Virtual screening methods have been developed and explored as useful tools for searching drug lead compounds from chemical ... Virtual screening methods as tools for drug lead discovery from large chemical libraries. ... Virtual screening methods as tools for drug lead discovery from large chemical libraries. Current Medicinal Chemistry 19 (32 ... we discussed the new developments in exploring virtual screening methods for enhanced performance in searching large chemical ...
Anticoagulant Activities and Multivariate Data Analysis for Drug Discovery. [email protected] Repository. ... Chemical analyses using HPLC and GC-MS were carried out. A. elliptica 70% v/v methanol extract and two compounds found in the ... Chemical and Pharmacological Studies of Ardisia Elliptica: Antiplatelet, Anticoagulant Activities and Multivariate Data ... CHING JIANHONG (2011-07-26). Chemical and Pharmacological Studies of Ardisia Elliptica: Antiplatelet, ...
Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids.: The effects have been ... Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids.. Authors * Breckenridge, A ... smoking or administration of drugs. Phenobarbitone and the antibiotic rifampicin increase both oestrogen and progestogen ...
Misuse of immunosuppressive drugs. Immunosuppressive drugs used in cancer chemotherapy or to suppress rejection of organ ... Radiation and hazardous chemicals. Exposure to radiation and hazardous chemicals may also damage the immune system. Excessive ... Donald Calne (1936- ) showed in 1960 that immunosuppressive drugs, drugs that suppress immune responses, reduced transplant ... To combat these reactions, many people take drugs that deactivate histamine. These drugs, called antihistamines, are available ...
Effects of drugsEdit. Main article: neuropharmacology. One of the most important features of chemical synapses is that they are ... Synapses are affected by drugs such as curare, strychnine, cocaine, morphine, alcohol, LSD, and countless others. These drugs ... rather than the 20 to 40 nm distance that separates cells at chemical synapses.[25][26] As opposed to chemical synapses, the ... Signaling in chemical synapsesEdit. OverviewEdit. Here is a summary of the sequence of events that take place in synaptic ...
... by specification as a research chemical) and/or avoid detection in standard drug tests.[5] Many designer drugs and research ... Interest in the drugs tended to focus on either the potential for psychotherapeutic applications of the drugs (see psychedelic ... The 3-pronged test for schedule 1 drugs is as follows: the drug has no currently accepted medical use, there is a lack of ... Glennon RA (October 1999). "Arylalkylamine drugs of abuse: an overview of drug discrimination studies". Pharmacology ...
... a drug made from the milky juice of unripe seed capsules of the opium poppy plant. ... The chemical works of E. Merck, established in 1827 to manufacture morphine, began producing codeine the same year the drug was ... Schedule III drugs have a lower potential for abuse than drugs in Schedule II, and abuse of the drug may lead to moderate or ... Over time, certain drugs begin to lose their effectiveness, and users need to take more and more of the drug to achieve the ...
The heart of chemical biology and drug discovery. Together they form a unique fingerprint. * Drug Discovery Chemical Compounds ... Jung, H. J., & Kwon, H. J. (2015). Target deconvolution of bioactive small molecules: The heart of chemical biology and drug ... Jung, HJ & Kwon, HJ 2015, Target deconvolution of bioactive small molecules: The heart of chemical biology and drug discovery ... Target deconvolution of bioactive small molecules : The heart of chemical biology and drug discovery. / Jung, Hye Jin; Kwon, Ho ...
Natural products used as a chemical library for protein-protein interaction targeted drug discovery. In: Journal of Molecular ... Natural products used as a chemical library for protein-protein interaction targeted drug discovery. Journal of Molecular ... Dive into the research topics of Natural products used as a chemical library for protein-protein interaction targeted drug ... Natural products used as a chemical library for protein-protein interaction targeted drug discovery. / Jin, Xuemei; Lee, ...
For the most current and complete list of drugs and chemicals affecting pregnancy, please refer to the US Food and Drug ... This partial list of chemicals is from studies that found evidence of specific chemicals adverse human health effects. ... But other chemicals are known to have an adverse effect on pregnancies. A child healthcare provider can offer guidance on these ... Antineoplastic drugs. Miscarriage, low birth weight, birth defects. Certain ethylene glycol ethers such as 2-ethoxyethanol (2EE ...
Chemical Properties. *Chemometric Modeling. *Drug Design Applications. *Environmental Fate Modeling. *Material Property ... In presenting key research in the field of chemical research, IJQSPR aims to advance the current literature available across ... chemical engineering, pharmaceutical and medicinal chemistry, pharmacokinetics, toxicology (including ecotoxicology), and ... chemical engineering, pharmaceutical and medicinal chemistry, pharmacokinetics, toxicology (including ecotoxicology), and ...
Adriano Andricopulo, Brazilian Chemical Society, Brazil. Emili Besalu, University of Girona, Spain. Ramon Carbo-Dorca, ... "Quantitative Structure-Activity Relationships in Drug Design, Predictive Toxicology, and Risk Assessment" (IGI Global, 2015). ... In presenting key research in the field of chemical research, IJQSPR aims to advance the current literature available across ... chemical engineering, pharmaceutical and medicinal chemistry, pharmacokinetics, toxicology (including ecotoxicology), and ...
... chemical reaction engineering; combustion synthesis of materials; drug delivery systems; ecological modeling;... ... Chemical and Petroleum Engineering. The department offers the M.S. degree in the fields of chemical engineering and petroleum ... Chemical Engineering. The chemical engineering graduate program offers an extensive selection of courses, and the University of ... Chemical Engineering. 51 quarter-hours with a grade of C or better in each course, with a minimum graduate grade point average ...
Substance Abuse Counselor Graduate Schools may go by a variety of names, like drug and alcohol counseling degree, addiction ... studies degree, chemical dependence services degree, and others. Graduate substance abuse counselor schools may offer degrees ...
Drugs and Medicine. Pharmaceutical products, biopharmaceuticals, dialysis. How many years I have to study? ... In a simpler way, Chemical engineers transform raw matter or chemicals into a more valuable and useful products. ... Currently, employment opportunities for Chemical Engineers in Puerto Rico are in: Pharmaceutical Industry, Chemical Products, ... and control of chemical, physical and biological processes, including a risks assessment of them. Chemical engineers discover, ...
Transforming Printmaking through Chemical Innovation. Cell-Mediated Delivery of Drugs to Tumors In collaboration with Deryl L. ... Copper Activated Drugs Against Gram-positive Bacteria. Copper-activated drugs against Methicillin-resistant Staphylococcus ... Transforming Printmaking through Chemical Innovation In collaboration with Jason Scuilla, master printmaker and Associate ... we have developed peptide-based nanosponges for the delivery of drugs, DNA, and RNA to leucocytes in peripheral blood.8 The ...
The team says tests show the drug to be effective against 15 common viruses they have so far tested it against - suggesting it ... MIT researchers have developed a drug that may be to viral infections what penicillin was to their bacterial counterparts. ... "In theory, it should work against all viruses," says Todd Rider, a senior staff scientist in Lincoln Laboratorys Chemical, ... The drug works by targeting a type of RNA produced only in cells that have been infected by viruses. " ...
using drugs. *certain types of medication, such as medications used to treat epilepsy ... "There are growing concerns over everyday chemical exposure effects because many chemicals have the potential to interfere with ... pregnant women are exposed to a complex mixture of hundreds of chemicals at low levels and exposure to such chemicals can occur ... Controversial advice on chemicals in pregnancy. The Daily Mail reports on the warning for pregnant women that household ...
A stepped-care approach to drug therapy may provide the most rational, cost-efficient approach to management of this disease. ... drug- or chemical-induced; infection; uncommon forms of immune-mediated diabetes; genetic syndromes (e.g., Down syndrome, ... Drugs. 1996;51:931-41.. 15. Scheen AJ. Drug treatment of non-insulin-dependent diabetes mellitus in the 1990s. Achievements and ... With the labeling of tolbutamide (Orinase) by the U.S. Food and Drug Administration in 1962, the sulfonylurea class of drugs ...
Avoiding chemical exposures can be difficult but with the right knowledge it is possible to minimize chemical exposure and thus ... Chemical avoidance is important for sufferers of multiple chemical sensitivity (MCS). Volatile organic compounds (VOCs) are of ... Water, Drugs and Food Additives. Drinking water, prescription drugs and food additives are all sources of chemicals which may ... Reducing intake of chemicals in foods and water and in the form of drugs is also important. We will look at measures that can ...
Drug Discovery Today 2015 20(3):296-300.]. *Shockley KR. Using weighted entropy to rank chemicals in quantitative high- ... Drug Discovery Today 2015 20(3):296-300. [Abstract Shockley KR. Quantitative high-throughput screening data analysis: ... Developmental effects of the ToxCastâ„¢ Phase I and II chemicals in Caenorhabditis elegans and corresponding responses in ... Developmental effects of the ToxCastâ„¢ Phase I and II chemicals in Caenorhabditis elegans and corresponding responses in ...
Drug metabolism and disposition: the biological fate of chemicals. 44(9):1463-1479. [Abstract Jackson, JP, Linhao, L, Deibert, ... drug clearance, and drug-drug interaction pathway research. Ferguson also has a background in contract research management ... Drug metabolism and disposition: the biological fate of chemicals. 44(9):1463-1479.] ... In vitro assessment of metabolic drug-drug interaction potential of AZD2624, neurokinin-3 receptor antagonist, through ...
Won (Cancer Drug/Gene Delivery, Imaging, Theranosis) *Yuan (Biomaterials, Protein Engineering) Electronics *Agrawal (Solar Cell ... Chemical Engineering Research Areas. Davidson School of Chemical Engineering at Purdue University has a commitment to ... GAANN Fellows in Chemical Engineering Energy Education will receive the following:. *Full funding for all tuition and fees for ... GAANN Fellowships in Chemical Engineering Energy Education Thanks to grant funding from the Department of Educations Graduate ...