Center for Brain Immunology & Glia (BIG) - Research output - Research Profiles at Washington University School of Medicine
Obstructive sleep apnea decreases central nervous system-derived proteins in the cerebrospinal fluid. Ju, Y. E. S., Finn, M. B. ... Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease. Vlassenko, A. G., McCue, L., Jasielec, M. S. ... The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging. ...
Can a biomarker in the eye be an indicator of neurodegeneration? - Innovation Toronto
Neurofilament light chain, a protein previously detected in cerebrospinal fluid and blood that is being explored as a biomarker ... and they have been detected in cerebrospinal fluid, blood, and in fluid around the eye. ... Researchers have used a machine-learning model to analyze blood proteins to estimate the biological, as opposed to the ... For this study, the researchers collected eye fluid samples from 77 patients who were undergoing previously scheduled eye ...
Neonatal chikungunya - a case report | Pediatric Oncall Journal
Cerebrospinal fluid (CSF) analysis showed protein 304mg%, sugar-66mg%, cells-15/cumm with neutrophils 95% and lymphocytes 5%. ... in amniotic fluid. The time of greatest risk of transmission of Chikungunya virus from mother to fetus appears during birth if ... a negative C-reactive protein, calcium 8.6 mg%, sodium 130 meq/L, potassium 4.5 meq/L, chloride 100 Meq/L. ...
Searching for clues: tracking the pathogenesis of human immunodeficiency virus central nervous system disease by use of an...
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Acervo Digital: Papiloma de plexo coroide em um cão
Organ in brain fights Alzheimer plaques - ScienceBlog.com
... and prevents it from building up in the cerebrospinal fluid. ... a critical role in preventing the accumulation of a protein ... The researchers found that the choroid plexus acts as a sort of fishnet that captures the protein, called beta-amyloid, ... times more beta-amyloid from cerebrospinal fluid compared to how much of the protein the cells allowed to pass into the fluid. ... The research focused on how the choroid plexus works to clean beta-amyloid from the cerebrospinal fluid. Studies using rat ...
Association between febrile seizures and enterovirus and parechovirus infection in the emergency room: A pilot study | Anales...
AGE, acute gastroenteritis; AOM, acute otitis media; AP, acute pharyngitis; CPR, C-reactive protein; CSF, cerebrospinal fluid; ... who described seizures in 8 out of 12 children aged less than 4 years in whom HPeV had been detected in cerebrospinal fluid ( ... We only found differences in the body temperature and the CSF protein concentration in patients with a positive EV or HPeV PCR ...
Cerebrospinal fluid biomarker supported diagnosis of Creutzfeldt-Jakob disease and rapid dementias: a longitudinal multicentre...
A total of 29 022 cerebrospinal fluid samples were analysed for 14-3-3 protein and other cerebrospinal fluid dementia markers ... Cerebrospinal fluid protein 14-3-3 detection remains an important test in the diagnosis of Creutzfeldt-Jakob disease. Due to a ... Protein 14-3-3 specificity was analysed for Creutzfeldt-Jakob disease with respect to increasing cerebrospinal fluid tests per ... cerebrospinal fluid analysis, particularly protein 14-3-3 testing, presents an important approach in the identification of ...
Center for Brain Immunology & Glia (BIG) - Research output - Research Profiles at Washington University School of Medicine
Cerebrospinal fluid proteins predict longitudinal hippocampal degeneration in early-stage dementia of the Alzheimer type. Wang ... Cerebrospinal fluid APOE levels: An endophenotype for genetic studies for Alzheimers disease. Cruchaga, C., Kauwe, J. S. K., ... Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation ... Origins of Alzheimers disease: Reconciling cerebrospinal fluid biomarker and neuropathology data regarding the temporal ...
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Cerebrospinal fluid extracellular vesicle enrichment for protein biomarker discovery in neurological disease; multiple ... Cerebrospinal fluid extracellular vesicle enrichment for protein biomarker discovery in neurological disease; multiple ... Cerebrospinal fluid complement system biomarkers in demyelinating disease. Multiple Sclerosis 26(14), pp. 1929-1937. (10.1177/ ... Cerebrospinal fluid complement system biomarkers in demyelinating disease. Multiple Sclerosis 26(14), pp. 1929-1937. (10.1177/ ...
Pesquisa | Portal Regional da BVS
Patients with cerebrospinal fluid protein , 200 mg/dL presented more brain calcifications (p = 0.0325). Other sequelae were ... The aim of this study was to evaluate an enzyme-linked immunoassay with recombinant rhoptry protein 2 (ELISA-rROP2) for its ... The aim of this study was to evaluate an enzyme-linked immunoassay with recombinant rhoptry protein 2 (ELISA-rROP2) for its ... Evaluation of a recombinant rhoptry protein 2 enzyme-linked immunoassay for the diagnosis of toxoplasmosis acquired during ...
Detection and measurement of an endogenous clonidine-displacing substance in human cerebrospinal fluid<...
CSF protein or number of cells. CDS levels in CSF were higher than those in the serum (P , 0.01). We conclude that CDS is ... We examined for the first time whether CDS can be detected and measured in human cerebrospinal fluid (CSF). Using the [3H] ... We examined for the first time whether CDS can be detected and measured in human cerebrospinal fluid (CSF). Using the [3H] ... We examined for the first time whether CDS can be detected and measured in human cerebrospinal fluid (CSF). Using the [3H] ...
Neurosurgery - Scholarly Output - Augusta University Research Profiles
Congenital disorders of glycosylation. Medical search
... we tested isoforms of beta-trace protein (beta TP), a brain-type glycosylated protein in cerebrospinal fluid (CSF) of nine ... beta-Trace protein in human cerebrospinal fluid: a diagnostic marker for N-glycosylation defects in brain. (7/113). As ... These can be divided ... disorders of protein N-glycosylation, disorders of protein O-glycosylation, disorders of lipid ... Protein Isoforms. Different forms of a protein that may be produced from different GENES, or from the same gene by ALTERNATIVE ...
Nicholas Anstey - Research Outputs - Charles Darwin University
Cerebrospinal fluid metabolites as biomarkers to distinguish between viral and autoimmune encephalitis | PPT
Cerebrospinal fluid metabolites as biomarkers to distinguish between viral and autoimmune encephalitis - Download as a PDF or ... A Sub-network of Signaling Protein Complexes in AA May Provide New Molecular .... National Alopecia Areata Foundation•1.9K. ... Cerebrospinal fluid metabolites as biomarkers to distinguish between viral and autoimmune encephalitis •1 like•92. views ... Similar to Cerebrospinal fluid metabolites as biomarkers to distinguish between viral and autoimmune encephalitis (. 20. ). ...
Medical Science Monitor | A tabular approach to the sequence-to-structure relation in proteins (tetrapeptide representation)...
MATERIAL/METHODS: The polypeptide chains of all the proteins in the Protein Data Bank were transformed into their early-stage ... The sequence-to-structure and structure-to-sequence relation is critical for predicting protein structure. A contingency table ... Their correlation seems to be essential in protein-folding simulation. ... Experimental observations classify the protein-folding process as a multi-step event. The backbone conformation has been ...
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Alzheimer's Research & Therapy | Articles
Evaluation of cerebrospinal fluid levels of synaptic vesicle protein, VAMP-2, across the sporadic Alzheimers disease continuum ... Systematic review: fluid biomarkers and machine learning methods to improve the diagnosis from mild cognitive impairment to ... Clinical and biological relevance of glial fibrillary acidic protein in Alzheimers disease There is a tremendous need for ... Neuronal transcriptome, tau and synapse loss in Alzheimers knock-in mice require prion protein Progression of Alzheimers ...
Bioinformatics Graz - Papers
... microparticles isolated from cerebrospinal fluid of brain injured patients are messengers carrying mRNAs, miRNAs and proteins. ... Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function. FEMS ... proteins of the hepatic stellate cell-line HSC-T6.. J Lipid Res. 2015. 56(10):1972-1984 , PMID: 26330055. ... A study based on Plasmodium falciparum mRNA and protein data.. BMC Syst Biol. 2014. 8(Suppl 2):S4 , PMID: 25033389. ...
Detecting Multiple Sclerosis Mimics Early
Cerebrospinal fluid pleocytosis exceeding 50 white blood cells/cm 3 *. Cerebrospinal fluid protein exceeding 1 g/l ... Despite recent refinements in diagnostic criteria and the availability of ancillary studies, such as cerebrospinal fluid ... optical coherence tomography and cerebrospinal fluid (CSF) analysis; however, there is no single test that is specific enough ...
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Exploring the Role of Aggregated Proteomes in the Pathogenesis of Alzheimer's Disease. - Amrita Vishwa Vidyapeetham
Elevated levels of (Aβ), total tau (t-tau) and phosphorylated tau (ptau) in cerebrospinal fluid (CSF) have become an important ... The aggregation of Aβ peptide derived from amyloid precursor protein initiates a series of events that involve inflammation, ... in Thermal & Fluids Engineering(Augmented with Artificial Intelligence and Machine Learning). *M. Tech. in Thermal Sciences and ... Source : Curr Protein Pept Sci, Volume 21, Issue 12, p.1164-1173 (2020) ...
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Alzheimer's Disease Symptoms | CareLinx
Beta-amyloid accumulation, detectable by PET imaging or cerebrospinal fluid testing. *Tau protein found in cerebrospinal fluid( ... The degrading of nerve cells is thought to be caused by the accumulation of abnormally folded proteins leading to atrophy, or ... The genes are as follows; Apolipoprotein E 4 (ApoE-ε4), Amyloid precursor protein (APP), Presenilin-1 and 2 (PS-1 and PS-2). ...