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*  Cell Transformation, Neoplastic - MeSH - NCBI
All MeSH CategoriesDiseases CategoryNeoplasmsNeoplastic ProcessesCarcinogenesisCell Transformation, NeoplasticBlast CrisisCell ... Signs and SymptomsPathologic ProcessesNeoplastic ProcessesCarcinogenesisCell Transformation, NeoplasticBlast CrisisCell ... Cell Transformation, Neoplastic. Cell changes manifested by escape from control mechanisms, increased growth potential, ... Transformation, Neoplastic Cell. *Neoplastic Transformation, Cell. *Cell Neoplastic Transformation. *Cell Neoplastic ...
https://www.ncbi.nlm.nih.gov/mesh?term=Cell%20Transformation,%20Neoplastic
*  What does cell transformation, neoplastic mean?
... neoplastic. What does cell transformation, neoplastic mean? Information and translations of cell transformation, neoplastic in ... neoplastic in the Definitions.net dictionary. Meaning of cell transformation, ... What does cell transformation, neoplastic mean?. Definitions for cell transformation, neoplastic. Here are all the possible ... cell, constant. Alternative searches for cell transformation, neoplastic:. *Search for Synonyms for cell transformation, ...
https://www.definitions.net/definition/cell%20transformation,%20neoplastic
*  γ-Secretase-Dependent Proteolysis of CD44 Promotes Neoplastic Transformation of Rat Fibroblastic Cells | Cancer Research
Cell, Tumor, and Stem Cell Biology γ-Secretase-Dependent Proteolysis of CD44 Promotes Neoplastic Transformation of Rat ... Alteration of DRM-associated cell surface proteins during transformation. A, DRMs from cell surface biotin-labeled Rat-1 cells ... cells] were compared with DRMs from transformed cells (MEN2A- or AP-stimulated RET-Fv-expressing cells) and transformation- ... Reversible Ret-dependent transformation of Rat-1 cells. Top, cells expressing Ret-Fv were unstimulated or stimulated with AP as ...
http://cancerres.aacrjournals.org/content/66/7/3681
*  Analysis of differentiation and transformation of cells by lectins.
This is thought to be accompanied by a modulation of cell surface determinants expressed on the outer cell membrane. Vice versa ... During differentiation cells are known to change their biological behavior according to their genotype. ... Cell Differentiation*. Cell Transformation, Neoplastic / analysis*. Lectins / analysis*. Chemical. Reg. No./Substance: 0/ ... 3818125 - Transformation-related changes in the expression of endogenous cell lectins.. 15348415 - Micro and nano-structured ...
http://www.biomedsearch.com/nih/Analysis-differentiation-transformation-cells-by/3067975.html
*  Coevolution of neoplastic epithelial cells and multilineage stroma via polyploid giant cells during immortalization and...
Spontaneous cell transformation: karyoplasts derived from multinucleated cells produce new cell growth in senescent human ... endothelial cells, and inflammatory cells [1-4]. Although it is well known that cancer epithelial cells and stromal cells ... Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev. 2001;15:50-65. ... the giant cells had recovered from H342 toxicity and had generated daughter cells, and the giant cells and daughter cells with ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC4918945/
*  Peritoneal fluid stimulates neoplastic transformation of normal HEK 293 cells by high expression of pluripotent genes
Their advanced stages are often characterized by the accumulation of ascites, which leads to spreading of cancer cells outside ... Ascites can be considered as microenvironmental affection for cancer cells [2]. Neoplastic cells are presented as single cells ... Peritoneal fluid stimulates neoplastic transformation of normal HEK 293 cells by high expression of pluripotent genes. Ilona ... Peritoneal fluid stimulates neoplastic transformation of normal HEK 293 cells by high expression of pluripotent genes. Polish ...
https://www.termedia.pl/Peritoneal-fluid-stimulates-neoplastic-transformation-of-normal-HEK-293-cells-by-high-expression-of-pluripotent-genes,55,34120,1,1.html
*  Neoplastic transformation of porcine mammary epithelial cells in vitro and tumor formation in vivo | BMC Cancer | Full Text
Oncogenic transformation was confirmed in vitro by anchorage-independent growth, increased cell proliferation, and expression ... Here we sought to establish a model for the efficient manipulation and transformation of porcine mammary epithelial cells (pMEC ... from stromal cells (CD140a+), with or without further enrichment for basal and luminal progenitor cells (CD49f+). These ... This is the first report describing a porcine model of mammary epithelial cell tumorigenesis that can be applied to the study ...
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-015-1572-7
*  Cellular and Molecular Studies of Growth, Differentiation and Neoplastic Transformation of Human Bronchial Epithelial Cells in...
Normal human cells in vitroappear to retain many normal phenotypic properties, remain diploid, eventually undergo senescence ... Bronchial Epithelial Cell Neoplastic Transformation Human Bronchial Epithelial Cell Squamous Differentiation Normal Human ... Cellular and Molecular Studies of Growth, Differentiation and Neoplastic Transformation of Human Bronchial Epithelial Cells in ... Differentiation and Neoplastic Transformation of Human Bronchial Epithelial Cells in Vitro. In: Feo F., Pani P., Columbano A., ...
https://rd.springer.com/chapter/10.1007/978-1-4757-9640-7_20
*  Tumorigenic Transformation and Neoplastic Progression of Human Uroepithelial Cells after Exposure in Vitro to 4-Aminobiphenyl...
Tumorigenic Transformation and Neoplastic Progression of Human Uroepithelial Cells after Exposure in Vitro to 4-Aminobiphenyl ... Tumorigenic Transformation and Neoplastic Progression of Human Uroepithelial Cells after Exposure in Vitro to 4-Aminobiphenyl ... Tumorigenic Transformation and Neoplastic Progression of Human Uroepithelial Cells after Exposure in Vitro to 4-Aminobiphenyl ... Tumorigenic Transformation and Neoplastic Progression of Human Uroepithelial Cells after Exposure in Vitro to 4-Aminobiphenyl ...
http://cancerres.aacrjournals.org/content/52/6/1606
*  Stress-Regulated Transcription Factor ATF4 Promotes Neoplastic Transformation by Suppressing Expression of the INK4a/ARF Cell...
Stress-Regulated Transcription Factor ATF4 Promotes Neoplastic Transformation by Suppressing Expression of the INK4a/ARF Cell ... Stress-Regulated Transcription Factor ATF4 Promotes Neoplastic Transformation by Suppressing Expression of the INK4a/ARF Cell ... Stress-Regulated Transcription Factor ATF4 Promotes Neoplastic Transformation by Suppressing Expression of the INK4a/ARF Cell ... Stress-Regulated Transcription Factor ATF4 Promotes Neoplastic Transformation by Suppressing Expression of the INK4a/ARF Cell ...
http://cancerres.aacrjournals.org/content/early/2012/01/05/0008-5472.CAN-11-1891
*  Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-Leukemia - Full Text View - ClinicalTrials.gov
Cell Transformation, Neoplastic. Carcinogenesis. Neoplastic Processes. Pathologic Processes. To Top. *For Patients and Families ... Precursor Cell Lymphoblastic Leukemia-Lymphoma. Leukemia, Lymphoid. Leukemia, Myeloid, Chronic-Phase. Leukemia, Myeloid, ... Underwent autologous or allogeneic stem cell transplant within 60 days prior to receiving the first dose of Ruxolitinib+ ...
https://clinicaltrials.gov/ct2/show/NCT01914484?recr=Open&cond=%22Leukemia%2C+Myelogenous%2C+Chronic%2C+BCR-ABL+Positive%22&rank=9
*  3-AP and High-Dose Cytarabine in Treating Patients With Advanced Hematologic Malignancies - Full Text View - ClinicalTrials.gov
Cell Transformation, Neoplastic. Carcinogenesis. Neoplastic Processes. Pathologic Processes. Cytarabine. Antimetabolites, ... 3-AP may help cytarabine kill more cancer cells by making them more sensitive to the drug. This phase I trial is studying the ... Drugs used in chemotherapy, such as cytarabine, work in different ways to stop cancer cells from dividing so they stop growing ... Precursor Cell Lymphoblastic Leukemia-Lymphoma. Leukemia, Lymphoid. Leukemia, Myelogenous, Chronic, BCR-ABL Positive. Blast ...
https://clinicaltrials.gov/ct2/show/NCT00077181
*  Flavopiridol in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Chronic...
Cell Transformation, Neoplastic. Carcinogenesis. Neoplastic Processes. Pathologic Processes. Eosinophilia. Leukocyte Disorders ... Post stem cell transplant allowed provided completion ≥ 4 months prior to study entry and no evidence of active acute or ... Drugs used in chemotherapy, such as flavopiridol, work in different ways to stop the growth of cancer cells, either by killing ... Precursor Cell Lymphoblastic Leukemia-Lymphoma. Leukemia, Lymphoid. Leukemia, Myelogenous, Chronic, BCR-ABL Positive. Blast ...
https://clinicaltrials.gov/ct2/show/NCT00101231?cond=%22Acute+monoblastic+leukemia%22&rank=19
*  Fludarabine Phosphate and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients...
Cell Transformation, Neoplastic. Carcinogenesis. Neoplastic Processes. Pathologic Processes. Fludarabine. Fludarabine phosphate ... The donated stem cells may replace the patient's immune system and help destroy any remaining cancer cells (graft-versus-tumor ... Sometimes the transplanted cells from a donor can also make an immune response against the body's normal cells. Giving ... before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells. It may also stop the patient's ...
https://clinicaltrials.gov/ct2/show/NCT00036738?recr=Open&cond=%22Leukemia%22&rank=17
*  Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Blast Phase Who Are Refractory to Imatinib Mesylate ...
Cell Transformation, Neoplastic. Carcinogenesis. Neoplastic Processes. Pathologic Processes. Decitabine. Imatinib Mesylate. ... Patients who had received hematopoietic stem cell transplantation within 6 weeks of Day 1 decitabine therapy ...
https://clinicaltrials.gov/ct2/show/NCT00042003
*  BCL11A | Cancer Genetics Web
These results suggest that 14q32/miRNA clusters LOH may be another mechanism involved in lymphoid B cell transformation and ... We studied marginal zone B-cell lymphomas of the gastrointestinal tract including seven small cell lymphomas, eight large cell ... To outline further genetic mechanisms of transformation from follicular lymphoma (FL) to diffuse large B-cell lymphoma (DLBCL ... The same karyotype was confirmed in cells aspirated from skin infiltrates at Richter transformation. Atypical cytological ...
http://www.cancerindex.org/geneweb/BCL11A.htm
*  SOX2 gene | Cancer Genetics Web
Neoplastic Cell Transformation. Tag cloud generated 14 December, 2014 using data from PubMed, MeSH and CancerIndex. Notable (4) ... 3D cell cultures prolonged the survival and in vitro proliferation of neoplastic IDH1(R132H)-positive cells, however, did not ... Human marrow stromal cells downsize the stem cell fraction of lung cancers by fibroblast growth factor 10.. Mol Cell Biol. 2014 ... Cancer stem cells, as a subgroup of tumor cells, resemble critical properties of embryonic stem cells (ESCs) such as self- ...
http://www.cancerindex.org/geneweb/SOX2.htm
*  TCF7L1 | Cancer Genetics Web
Neoplastic Cell Transformation. *Nerve Tissue Proteins. *Cancer Gene Expression Regulation. *Repressor Proteins ... cells were detected in the ALDHpos FA‑HNSCC cells and not in the ALDHneg cells. FA‑HNSCC cell lines revealed enhanced in vitro ... Nat Cell Biol. 2015; 17(5):545-57 [PubMed] Related Publications How embryonic stem cells (ESCs) commit to specific cell ... PCA decreased cell viability in a dose-dependent manner in HCT116 and SW480 cells. In addition, PCA reduced cell viability in ...
http://www.cancerindex.org/geneweb/TCF7L1.htm
*  NOTCH2 gene | Cancer Genetics Web
Cell Proliferation. *Neoplastic Cell Transformation. *Molecular Sequence Data. *Apoptosis. *Tumor Markers. *Signal Transduction ... cell cycle arrest - cell fate determination - cell growth - cell surface - determination of left/right symmetry - embryonic ... a cancer stem cell marker) cells compared to control cells. The increase in CD133+ cells resulting from ARID3B expression was ... Recently, we have shown that Notch1 inhibition resulted in substantial cell death of non-small cell lung cancer (NSCLC) cells ...
http://www.cancerindex.org/geneweb/NOTCH2.htm
*  Classification of congenital melanocytic naevi and malignant transformation: a review of the literature.
Cell Transformation, Neoplastic. Humans. Infant, Newborn. Nevus, Pigmented / classification*, congenital, pathology. Risk ... and probably on the chance of malignant transformation. In this review, we summarise the literature on size subgroupings of CN ... Giant CN have an increased risk for malignant transformation, but the reported incidence rates have differed widely from one to ... with special focus on giant congenital naevi and their risk of malignant transformation. MATERIALS AND METHODS: A Medline ...
http://www.biomedsearch.com/nih/Classification-congenital-melanocytic-naevi-malignant/15544766.html
*  MYD88 | Cancer Genetics Web
TLR4 expression was present in all ovarian epithelium (normal and neoplastic), whereas MyD88 was restricted to neoplastic cells ... suggesting a multistep transformation of clonal B cells that, albeit benign (ie, IgM MGUS and smoldering WM), already harbor ... Both cases of FL were positive for CD10 and B-cell lymphoma 2 (BCL-2), and immunoglobulin heavy locus (IgH)/B-cell lymphoma 2 ... Next, the role of TLR4 in cell proliferation and migration was assessed using the TLR4-positive (TLR4(+)) melanoma cell lines ...
http://www.cancerindex.org/geneweb/MYD88.htm
*  FHL2 | Cancer Genetics Web
Neoplastic Cell Transformation. *Cell Nucleus. *Wnt Proteins. *p300-CBP Transcription Factors. *Chromosome 2 ... Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein ... Cell cycle and growth were assessed. The interaction between FHL2 and G0/G1 cell cycle and growth was evaluated by flow ... We also found high levels of TMED2 expression in BeWo but not in JEG-3 choriocarcinoma cell line. We used the BeWo cell line to ...
http://www.cancerindex.org/geneweb/FHL2.htm
*  Prognostic importance of DNA flow cytometry in non-Hodgkin's lymphomas.
Cell Transformation, Neoplastic. DNA, Neoplasm / analysis*. Flow Cytometry. Humans. Interphase. Lymph Nodes / pathology. ... estimates of S phase fraction prospectively identify patients with low grade non-Hodgkin's lymphoma at risk from transformation ...
http://www.biomedsearch.com/nih/Prognostic-importance-DNA-flow-cytometry/3722408.html
*  KAT5 | Cancer Genetics Web
HPDE6 cells (immortalized human pancreatic ductal epithelial cells) and corresponding adjacent non-neoplastic tissues were used ... hMOF knockdown attenuated OTSCC cell growth and transformation.. RESULTS: EZH2 (enhancer of zeste homolog 2) was up-regulated ... number of cells in the G0/G1 phase and a reduction in the number of cells in the S phase in both DLD-1 cells and SW480 cells. ... The definition of cell identity is a central problem in biology. While single-cell RNA-seq provides a wealth of information ...
http://www.cancerindex.org/geneweb/KAT5.htm
*  LRP1B | Cancer Genetics Web
Neoplastic Cell Transformation. *Gene Amplification. *RHOA. *Nucleic Acid Hybridization. *Lung Cancer. *Tumor Suppressor ... cell migration and invasion in HEK293 cells and renal cancer cells 127 in vitro. We further found that silencing of LRP1B ... Non-Small Cell Lung Cancer Lung Cancer Choi YW, Bae SM, Kim YW, et al.. Gene expression profiles in squamous cell cervical ... Down expression of LRP1B promotes cell migration via RhoA/Cdc42 pathway and actin cytoskeleton remodeling in renal cell cancer. ...
http://www.cancerindex.org/geneweb/LRP1B.htm