Transdifferentiation", ... Pancreatic Stem Cells. In Essentials of Stem Cell Biology: ... New cells are produced during adulthood, but their origin is not clear. Although much focus is on β-cell progenitors, it is not ... New cells are produced during adulthood, but their origin is not clear. Although much focus is on β-cell progenitors, it is not ... Pancreatic Stem Cells. / Dor, Yuval; Melton, Douglas A. Essentials of Stem Cell Biology: Third Edition. Elsevier Inc., 2014. p ...
Interaction of macrophages with apoptotic cells inhibits transdifferentiation and invasion of lung fibroblasts. Kim, Y. B., ... MCP-1 and MIP-3α Secreted from Necrotic Cell-Treated Glioblastoma Cells Promote Migration/Infiltration of Microglia. Jung, Y., ... Macrophages programmed by apoptotic cells inhibit epithelial-mesenchymal transition in lung alveolar epithelial cells via PGE2 ... Lee, Y. J., Kim, B. M., Ahn, Y. H., Choi, J. H., Choi, Y. H. & Kang, J. L., Mar 2021, In: Cells. 10, 3, p. 1-15 15 p., 501.. ...
The jellyfish is thought to achieve immortality through "transdifferentiation," or turning its cells back into stem cells and ... Although we have technically figured out how to turn human cells back into stem cells, humans have many cells that are sort of ... In theory, if those cells are forced back into a stem cell state, all of these contacts would be broken, since stem cells ... takes note of every contact a cell has, transdifferentiates that cell, then lets the newly generated cell grow around it like a ...
... β-cell, hepatocyte), the directed differentiation of OKSM iPSCs to β-cell and the transdifferentiation of hepatocytes to β-cell ... β-cell, hepatocyte), the directed differentiation of OKSM iPSCs to β-cell and the transdifferentiation of hepatocytes to β-cell ... δ-cells, PP-cells, ε-cells), endothelial and neuronal cells all contribute to this niche. ... δ-cells, PP-cells, ε-cells), endothelial and neuronal cells all contribute to this niche. ...
Then, release of nucleotides from collapsed vacuolated cell leads to the invasion and trans-differentiation of sheath cells ... Each vacuolated cell contains a single fluid filled vacuole that occupies most of the cellular volume. These cells are arranged ... Loss of KLF2 is accompanied by cell non-autonomous changes in mesenchymal cell proliferation and condensation, two key steps in ... During development, tissue dynamics, such as cell intercalations and oriented cell divisions, are critical for shaping tissues ...
keywords = "Plasticity, Quiescence, Regeneration, Stem cell, Transdifferentiation",. author = "Tetteh, {Paul W.} and Farin, { ... Plasticity within stem cell hierarchies in mammalian epithelia. In: Trends in Cell Biology. 2015 ; Vol. 25, Nr. 2. blz. 100-108 ... Plasticity within stem cell hierarchies in mammalian epithelia. Trends in Cell Biology. 2015 feb. 1;25(2):100-108. doi: 10.1016 ... Tetteh, PW, Farin, HF & Clevers, H 2015, Plasticity within stem cell hierarchies in mammalian epithelia, Trends in Cell ...
"Cell transdifferentiation, Embryonic stem cells, Pluripotent stem cells, Receptors, cytoplasmic and nuclear, Stem cells", ... cells and tissue-specific adult stem cells. Here, we review the role of the NR superfamily in various aspects of stem cell ... cells and tissue-specific adult stem cells. Here, we review the role of the NR superfamily in various aspects of stem cell ... cells and tissue-specific adult stem cells. Here, we review the role of the NR superfamily in various aspects of stem cell ...
However, recent investigations using cell lineage tracing techniques have demonstrated that many, perhaps the majority, of bone ... cells are derived via direct transformation from chondrocytes. In this review, the authors will briefly discuss the history of ... this idea and describe recent studies that clearly demonstrate that the direct transformation of chondrocytes into bone cells ... current concept regarding endochondral bone formation postulates that most hypertrophic chondrocytes undergo programmed cell ...
Acinar to ductal cell trans-differentiation: A prelude to dysplasia and pancreatic ductal adenocarcinoma. Parte, S., ... Ogunleye, A. O., Nimmakayala, R. K., Batra, S. K. & Ponnusamy, M. P., May 2023, In: STEM CELLS. 41, 5, p. 417-430 14 p.. ... Kaushik, G., Ponnusamy, M. P. & Batra, S. K., Sep 2018, In: STEM CELLS. 36, 9, p. 1329-1340 12 p.. Research output: ... Cancer stem cells and therapeutic targets: An emerging field for cancer treatment. Vaz, A. P., Ponnusamy, M. P. & Batra, S. K. ...
... we demonstrate that antiangiogenic immune-modulating therapies evoke transdifferentiation of postcapillary venules into ... CD8 T cell progenitors that differentiate into GrzB+PD1+ CD8 T effector cells. Tumor-HEVs require continuous CD8 and NK cell- ... The lack of T cell infiltrates is a major obstacle to effective immunotherapy in cancer. Conversely, the formation of tumor- ... By employing single-cell transcriptomics, endothelial fate mapping, and functional multiplex immune profiling, ...
These cells can differentiate into multiple lineages. The isolation, characterization, transdifferentiation, cell- gel ... Cells Antigen-Presenting Cells Antineoplastic Immunotherapies Autoimmune Lupus Blood Cells Bone Marrow Cells Cell-Biology ... Cells Enzyme Activity Epithelial Cells Erythroid Cells Evolutionary Immunology Familiy Medicine Fibromyalgia Germ Cells ... Mesenchymal Progenitor Cells from Different Sources and their Potential to Differentiate In Vitro into Muscle Cells Author(s): ...
Cell Transdifferentiation. 1. 2010. 32. 0.100. Why? Cloning, Molecular. 3. 2011. 570 ...
The first insights into regulation of cell transdifferentiation during gut regeneration in Eupentacta fraudatrix. ... In the work, ChIP-seq peaks were used to study the stem cell niche of three plants, among which the well-known Talus ( ... It has been repeatedly confirmed that regeneration is only due to the transformation of terminally differentiated cells. In ... Systems Biology and Biomedicine symposium Human retinal photoreceptor cells in glaucoma: destructive changes of mithochondria ...
Such non-mutational processes are largely driven by tumor cell plasticity, which renders tumor cells insusceptible to the drug- ... targeted pathway, thereby facilitating the tumor cell survival and growth. The concept of tumor cell plasticity highlights the ... This expanded knowledge of tumor cell plasticity contributes to developing novel therapeutic strategies or combination therapy ... acquisition properties of cancer stem cells, and trans-differentiation potential during drug exposure. From observations in ...
Cell Transdifferentiation MeSH DeCS ID:. 52892 Unique ID:. D054337 Documents indexed in the Virtual Health Library (VHL):. ... Cell Dedifferentiation - Preferred Concept UI. M0504224. Scope note. A reverse developmental process in which terminally ... A reverse developmental process in which terminally differentiated cells with specialized functions revert back to a less ... differentiated cells with specialized functions revert back to a less differentiated stage within their own CELL LINEAGE. ...
Implications on conjunctival epithelial transdifferentiation and warzone unlocker free download cells. With more than, members ... cell phone number and emergency contact number. It is also the most robust platform through which to get China market updates ... low affinity nerve overwatch 2 download cheat factor receptor rapid fire combat master long-term denervated Schwann cells. ...
The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research ... The studies will include assessing beta-cell neogenesis, proliferation and transdifferentiation, and how such cellular changes ... and cell-cell interactions that can promote β-cell regeneration. ... The Department of Cell and Molecular Biology (CMB) is a ... CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and ...
I conclude that transdifferentiation of human stem cells to a mature hepatocyte phenotype does not occur in the NOD/Scid model ... To achieve true transdifferentiation a different, more chronic type of tissue damage, or a better defined stem cell population ... Liver damage has been suggested as one of the factors influencing homing of stem cells to the liver and transdifferentiation of ... To investigate the developmental potential of human stem cells I used xenotransplantation of stem cells purified from cord ...
BCLAF1 is a novel gene implicated in smooth muscle cell survival and transdifferentiation in atherosclerosis ... Extracellular S100A4 and PDGF-BB act in synergy to induce smooth muscle cell phenotypic transition and activation: implications ...
prolactin secreting cell differentiation (GO:0060127) is_a cell differentiation transdifferentiation (GO:0060290) is_a cell ... fat cell differentiation (GO:0045444) is_a cell differentiation compound eye cone cell differentiation (GO:0042675) is_a cell ... pollen sperm cell differentiation (GO:0048235) is_a cell differentiation lung cell differentiation (GO:0060479) is_a cell ... skeletal muscle cell differentiation (GO:0035914) is_a cell differentiation tendon cell differentiation (GO:0035990) is_a cell ...
... or T-cell lymphomas or leukemias Microscopic Pathology Partial or complete replacement of… ... Interdigitating Reticulum Cell Sarcoma Wesley O. Greaves, MD L. Jeffrey Medeiros, MD Cyril Fisher, MD, DSc, FRCPath Key Facts ... B-cell lymphoma might transform to histiocytic phenotype via "transdifferentiation". *. Possibly due to loss of key components ... Antigen-presenting cell involved in T-cell immunity. *. Derived from CD34(+) lymphoid/myeloid progenitor cell in bone marrow ...
... is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose ... Beta Catenin in Cell Adhesion and T-cell Signaling. Beta Catenin is a cytosolic, 88 kDa intracellular protein that tightly ... Mol Cell Biol 2017-08-11 [PMID: 28630279] Al-Khalaf HH, Aboussekhra A. p16INK4A induces senescence and inhibits EMT through ... Specificities of small cell neuroendocrine prostate cancer: Adverse prognostic value of TTF1 expression. Urol Oncol. 2020-07-29 ...
keywords = "Bone marrow cell transdifferentiation, Chimerism, Confocal and light microscopy, Enhanced green fluorescent protein ... Concise review : Stem cells, myocardial regeneration, and methodological artifacts. In: Stem Cells. 2007 ; Vol. 25, No. 3. pp. ... Concise review: Stem cells, myocardial regeneration, and methodological artifacts. Stem Cells. 2007 Mar;25(3):589-601. doi: ... In: Stem Cells, Vol. 25, No. 3, 03.2007, p. 589-601.. Research output: Contribution to journal › Review article › peer-review ...
Many noteworthy hypotheses possess surfaced including immediate transdifferentiation from the adoptively moved stem cells or ... Similar results have been noticed whereby the donated stem cells including mesenchymal stem cells, cardiac progenitor cells, ... The CADUCEUS trial used produced cells, a heterogeneous mixture of c-kit+, CD90+ and CD105+ cells, demonstrated humble ... complicated the transdifferentiation IRA1 hypothesis. Furthermore, follow-up studies of sufferers signed up for cell therapy ...
Cyclic AMP plays an important role in differentiation, transdifferentiation and proliferation of pancreatic cells. Isolated ... Cyclic CMP and cyclic UMP concentrations are regulated by the cell proliferation status because growth-arrest of cells resulted ... by enhancing the release of pancreatic enzymes from the acinar cell, can overcome the acinar cell injury induced by high ... current activation in pancreatic duct cells via cyclic GMP. Using whole-cell patch-clamp forskolin increased of Cl- conductance ...
Cell-based therapy with mesenchymal stem cells or renal progenitor cells (RPCs) resident in the kidney has appeared to be an ... Embryonic stem cells or induced pluripotent stem cells (iPSCs) are also utilized for AKI recovery. However, the therapeutic ... We showed that the differentiation efficiency of iPSCs to RPCs increased when cultured with renal epithelial cell growth medium ... cell proliferation, and the expression of pro-renal factors. Our results revealed that iPSC-derived RPCs can protect AKI rat ...
Transdifferentiation of Bone Marrow Pro-B Cells into Bone-Resorbing Osteoclasts-an Unexpected Role for Erythropoietin. Deshet- ... B cell depletion by anti-CD20 antibodies entrains trabecular bone loss in mice.. Kolomansky, A., Deshet-Unger, N., Ostrovsky, A ... Pharmacological B Cell Depletion by Anti-CD20 Antibody Induces Trabecular Bone Loss in Mice. Kolomansky, A., Deshet-Unger, N., ... Erythropoietin (EPO) Regulates Bone Mass Via EPO Receptors on Myeloid and Lymphocytic Cells. Hiram-Bab, S., Kolomansky, A., ...
Leukemic Cancer Stem Cells. - Plasticity, Transdifferentiation and Reprogramming. - Therapeutic use of Stem Cells: Aging and ... by which stem cells can generate various cell types of the blood and immune system.The successful generation of blood cells ... Summarise the current understanding of stem cell biology;. - Critique the latest experimental approaches in stem cell research ... induced pluripotent stem cells and regenerative medicine) in stem cell research will be discussed.. Learning outcomes. By the ...
T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells Laura Kiekens (UGent) , Sigrid ... From IL-17 to IFN-γ in inflammatory skin disorders : is transdifferentiation a potential treatment target? Arno Belpaire (UGent ... liver CD8αhigh and circulating blood CD8αhigh NK cells reveals an intermediate phenotype of liver CD8αhigh NK cells Leen ...
Transdifferentiation and remodeling of post-embryonic C. elegans cells by a single transcription factor.. Development. 140(24): ... Transorganogenesis and transdifferentiation in C. elegans are dependent on differentiated cell identity.. Dev Biol. 420(1):136- ...