In comparison to cells expressing the CD4 receptor alone, DP T-cells showed: (1) increased proliferation; (2) higher and more ... Co-expression of the CD8 receptor in a human CD4+ T-cell clone influences proliferation, cytosolic Ca2+ release and cytokine ... In comparison to cells expressing the CD4 receptor alone, DP T-cells showed: (1) increased proliferation; (2) higher and more ... from the same clone, CD4 single positive (SP) cells from those co-expressing CD4/CD8 receptors (DP cells) and stimulated them ...

Results: Increased levels of POGLUT2 was found in multiple types of cancer tissues and cell lines. Moreover, increased gene ... Furthermore, POGLUT2 knockdown of breast cancer cells was established, followed by in vitro biological function assays and in ... POGLUT2 was mainly expressed in stromal cells as verified by StromalScore, ESTIMATEScore, ImmuneScore, and Tumor purity, and ... POGLUT2 was mainly expressed in stromal cells as verified by StromalScore, ESTIMATEScore, ImmuneScore and Tumor purity and ...

2007). "Cloning of B cell-specific membrane tetraspanning molecule BTS possessing B cell proliferation-inhibitory function". ... electrically excitable cells and respiratory epithelial cells. The proton-conducting HVCN1 channel has only transmembrane ... Cell. 140 (3): 327-37. doi:10.1016/j.cell.2009.12.053. PMID 20144758. S2CID 7952753. Kimura K, Wakamatsu A, Suzuki Y, et al. ( ... Trends Cell Biol. 21 (1): 20-8. doi:10.1016/j.tcb.2010.09.006. PMC 3014425. PMID 20961760. Lee SY, Letts JA, MacKinnon R (April ...

... resulting in clonal proliferation. Cell clones then produce multiple nodules. ... Increased thyroid cell replication predisposes single cells to somatic mutations of the TSH receptor. Constitutive activation ... In vitro systems have shown stimulation of thyroid follicular cell proliferation with insulinlike growth factor-1, epidermal ... Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors. ...

High expression of TYRO3 and AXL was detected in LMS cell lines. TYRO3 or AXL gene knockdown reduced cell proliferation/colony ... The TAM receptor and ligand expression was evaluated in LMS cell lines and 358 sarcoma samples by either gene expression or ... Cell viability/proliferation. Leiomyosarcoma cells were seeded into 96-wells plates at a density of 2000-5000 cells per well. ... Cell proliferation in shRNA clones were assessed by trypan blue exclusion at day 1 and 3 post cell seeding. ...

Single hybridoma cells are isolated by dilution cloning to generate cell clones that all produce the same antibody; these ... Proportions of κ and λ types vary by species and can be used to detect abnormal proliferation of B cell clones. Other types of ... The antibody isotype of a B cell changes during cell development and activation. Immature B cells, which have never been ... Activated B cells differentiate into either antibody-producing cells called plasma cells that secrete soluble antibody or ...

IL-7 induces dose-dependent proliferation of immature B cell precursors (18). Bone marrow cells were suspended in 0.3% agarose ... Soft agar cultures. B cell cloning in semisolid agar was performed using the method described by Kincade and colleagues (16, 17 ... Direct cell-cell contact between stromal cells and B cell precursors was not required for the androgenic effects. When bone ... so that the B cells were not in direct contact with the stromal cell layer. M2-10B4 stromal cells are known to produce B cell ...

... characterized by uncontrolled and progressive proliferation of a plasma cell clone. The proliferation of myeloma cells causes ... HuMax-CD38 also potently killed tumor cells from a patient with a CD38/138 positive plasma cell leukemia which was refractory ... About Diffuse Large B-Cell Lymphoma Diffuse Large B-Cell Lymphoma is a cancer of the B-lymphocytes and represents 30% of non- ... Depletion of OX40L-expressing cells was shown to depend on interaction of immune effector cells with the therapeutic antibody. ...

It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in hu ... The 3G8 antibody clone blocks neutrophil phagocytosis and stimulates NK cell proliferation. It has been reported that this ... Cell Type Dendritic cells, Macrophages, Monocytes, Neutrophils, NK cells Biology Area Immunology, Innate Immunity Molecular ... stimulation of NK cell proliferation4, blocking of phagocytosis5, and blocking of immunoglobulin binding to FcγRIII7,8. The ...

In addition, the II/41 clone has been reported not to stimulate B-cell proliferation.,/span> ... In addition, the II/41 clone has been reported not to stimulate B-cell proliferation.,/span> ... span style=font-family:Times,serif;font-size:9pt;>The II/41 clone has been reported to react specifically with mouse IgM of ... span style=font-family:Times,serif;font-size:9pt;>The II/41 clone has been reported to react specifically with mouse IgM of ...

... suggest imetelstat may have disease-modifying activity through the suppression of malignant progenitor cell clone proliferation ... and Ruxolitinib Depletes Myelofibrosis Hematopoietic Stem Cells and Progenitor Cells (Abstract #2963) ... In addition, the sequential treatment regimen did not affect normal hematopoietic stem and progenitor cells. As stated in the ... efficacious than using either drug alone in reducing myelofibrosis hematopoietic stem cells and hematopoietic progenitor cells ...

TIGIT is expressed on activated T cells, follicular T helper, memo ... T cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as VSTM3 or WUCAM, is a 26 kD, type I transmembrane protein ... This clone can suppress anti-CD3 induced T cell proliferation in vitro based on in-house testing.. This clone has been tested ... Follicular Helper T cells (TFH), NK cells.. Function Cell signaling, negative regulation of T cells, T cell tolerance, T cell ...

The proliferation and growth of PDAC cells were detected by Celigo analysis, MTT, and clone formation assay. Cell apoptosis was ... Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer. Med ... Cell proliferation assay. The AsPC-1 and PANC-1 cells infected by shPYCR1 or shCtrl lentivirus were seeded in a 96-well plate ... PYCR1 enhances the proliferation and inhibits the apoptosis of PDAC cell lines in vitro. After infection, the proliferation of ...

carbohydrate, charcoal, air pollutant, article, carbohydrate analysis, cell count, cell proliferation, clone, experiment, ... The main anatomical characteristics are three types of unicellular hairs, unequally sized epidermis cells of the leaf and a ... Root and shoot growth, assimilate partitioning and cell proliferation in roots of sitka spruce (Picea sitchensis) grown in ... The same experiment was repeated in each of two consecutive years using a different clone of Sitka spruce each year. Air was ...

Solitary extramedullary plasmacytoma (SEP) is a neoplastic proliferation of a single clone of plasma cells that occur outside ... HIV seropositivity and neoplasms with plasma cell morphology: plasmablastic lymphoma and plasma cell myeloma: is it a chance ... Solitary extramedullary plasmacytoma (SEP) is a neoplastic proliferation of a single clone of plasma cells that occur outside ... and other plasma cell tumours. This may be explained by the stimulatory effect of HIV on the plasma cells and co-infection with ...

... provide evidence that anti-OX40 prior to surgery is safe and can increase activation and proliferation of CD4+ and CD8+ T cells ... Peripheral blood phenotyping data show increases in CD4+ and CD8+ T cell proliferation two weeks after anti-OX40 administration ... Analyses of CD8+ TIL show increases in tumor-antigen reactive, proliferating CD103+ CD39+ cells in 25% of patients with ... in which 17 patients with locally advanced head and neck squamous cell carcinoma (HNSCC) received a murine anti-human OX40 ...

Interleukin-11 (IL-11) was initially cloned as a mediator of plasmacytoma cell proliferation and was later found to exhibit a ... Serial dilutions of Mouse IL-11 Recombinant Protein were added to B9 cells. Cell proliferation was measured and the linear ... Serial dilutions of Mouse IL-11 Recombinant Protein were added to B9 cells. Cell proliferation was measured and the linear ... The bioactivity of recombinant mIL-11 was determined in a B9 cell proliferation assay. The ED50 of each lot is less than or ...

Clonotypic Antibodies which Stimulate T Cell Clone Proliferation. Frelinger, J., Sing, A., Infante, A. & Fathman, C. G., Oct ... Biochemical characterization of B lymphoma cell antigen processing and presentation to antigen-reactive T cells. McKean, D. J. ... Definition of T cell idiotypes using anti-idiotypic antisera produced by immunization with T cell clones. Infante, A. J., ... T cell clones reactive with sperm whale myoglobin: Isolation of clones with specificity for individual determinants on ...

THOMAPLAST®-PS tissue culture plates are ideal auxiliaries for single cell isolation, hybridoma production, cloning, toxicity ... A special surface treatment guarantees optimal cell attachment and proliferation.. Raised well rims with recesses between the ... Dialysing Membranes, Dialysing Chambers, Dialysing Cells, Dialysing Sheets, Dialysing Bags * Borosilicate Glass Filter Disks ... Cell Culture Petri Dish made of PS, id: G40457, price: 1, brand: Reichelt, list: Similar Articles, position ...

... resulting from the proliferation of a single clone of plasma cells and which, during electrophoresis of serum, appears as a ... SEE ALSO: I cell. [immuno- + G. kytos, cell] immunocytoadherence (im′u-no-si′to-ad-her′ens). A method for determining cell ... Passive, cell-mediated i. produced by the transfer of living lymphoid cells from an immune (allergic or sensitive) animal to a ... in T cells, thus to interruption of cell activation. [immune + G. philos, fond, + in] immunopotentiation (im′u-no-po-ten-she-a′ ...

To ensure that cells being assessed for macropinocytosis are not undergoing cell death, we quantified cell proliferation ... S1G). Interestingly, DGKA downregulation with two shRNA clones decreased the proliferation of 105K cells by 20% (P , 0.0001) ... To determine the role of DGKA in the proliferation of Tsc2-deficient cells, we generated two cell lines with Tsc2 deficiency ... had no additional impact on the proliferation of shDGKA cells, indicating that the observed inhibition of proliferation is most ...

Cells transfected with CCL2 siRNA exhibited inhibited cell proliferation, cell cycle arrest and increased cellular apoptosis. ... but also in cervical cancer cell proliferation and clone formation, which were induced by overexpression of AKIP1. Furthermore ... Cell proliferation was measured using a Cell Counting kit‑8 assay, while cellular apoptosis and cell cycle distribution were ... Cell-Light EdU and colony formation assays were used to determine cell proliferation. CXCL1 and CXCL8 proteins were quantified ...

Cutaneous T-cell lymphoma is a term that was created in 1979 at an international workshop sponsored by the National Cancer ... memory T cells (CD45RO+) that normally patrol and home in on the skin. [21] The malignant clone frequently lacks normal T-cell ... This concept implies genetic instability followed by T-cell proliferation. Successive cell divisions of a genotraumatic T-cell ... The atypical cells show a CD3+, CD4−, CD8+, and CD30− T-cell phenotype with variable loss of pan-T-cell antigens (CD2, CD5, CD7 ...

... a diverse group of disorders of unknown etiology characterized by Disproportionate proliferation of a single clone of B cells ... and other plasma cell disorders Overview of Plasma Cell Disorders Plasma cell disorders are a diverse group of disorders of ... See also Overview of Plasma Cell Disorders Overview of Plasma Cell Disorders Plasma cell disorders are ... unknown etiology characterized by Disproportionate proliferation of a single clone of B cells Presence of a structurally and ...

... a diverse group of disorders of unknown etiology characterized by Disproportionate proliferation of a single clone of B cells ... Autologous peripheral blood stem cell transplantation Hematopoietic Stem Cell Transplantation Hematopoietic stem cell (HSC) ... See also Overview of Plasma Cell Disorders Overview of Plasma Cell Disorders Plasma cell disorders are ... especially after autologous stem cell transplantation Hematopoietic Stem Cell Transplantation Hematopoietic stem cell (HSC) ...

Olfactory cells occur all over the body, not just in the nose ... "Sandalore activated the cloned smeller cells in skin, thereby ... Cell proliferation after exposure to Sandalore also increased by more than 30 percent, the New Scientist adds. ... They exposed the cloned receptors to ten different synthetic odors derived from sandalwood-which was used by ancient East ... In a new study, researchers identified five different olfactory receptors on the surface of the skin and cloned one of those ...

The functions of circFAM13B were verified by proliferation assays, glycolysis assays, BCa cells-CD8+ T cell co-culture assays ... The function of CD8+ T cells was promoted by circFAM13B, and it could attenuate the glycolysis of BCa cells and reverse the ... Further mRNA sequencing was conducted, and the association of circFAM13B with glycolysis process and CD8+ T cell activation was ... Cell proliferation and cloning formation assays. The proliferation ability of BCa cells was assessed by seeding 2,000 T24 or ...

... the tip cell, appears at the distal part of each tubule. The tip cell is required for proliferation of the cells near to it ( ... clones of cells bearing the most extreme alleles are cell lethal and clones carrying weaker but still embryonic-lethal alleles ... However, the formation of the tracheal tree, which does not involve cell proliferation but cell migration and changes of cell ... cell proliferation and cell commitment. How the Emc protein may act in the specification of the diverse cell types affected in ...

In all these five CTL clones, autologous tumor cells suppressed IL-2-induced proliferation. The remaining four CTL clones, ... Cell Proliferation Medicine & Life Sciences 61% * Interleukin-2 Medicine & Life Sciences 49% ... In all these five CTL clones, autologous tumor cells suppressed IL-2-induced proliferation. The remaining four CTL clones, ... In all these five CTL clones, autologous tumor cells suppressed IL-2-induced proliferation. The remaining four CTL clones, ...