Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion...
PLZF-RAR alpha expression blocks terminal differentiation of hematopoietic precursor cell lines (U937 and HL-60) in response to ... Transforming Growth Factor beta; Gene Expression Regulation; Monocytes; Mutation; Signal Transduction; Oncogene Proteins, ... Cholecalciferol; HL-60 Cells; DNA-Binding Proteins; Humans; Kruppel-Like Transcription Factors; Transglutaminases; Cell ... increases RA sensitivity of hematopoietic precursor cells and restores RA sensitivity of RA-resistant hematopoietic cells; (iii ...https://air.unimi.it/handle/2434/195550
What does TCGA uses a a reference for making snp annotation?
Transformed cancer cell-lines RNA-seq database Hi, I am trying to find a database which has RNA-seq data for cancer cell-lines ...https://www.biostars.org/p/368390/
Looking For Rna-Seq Data Sets Of Breast Cancer Or Liver Cancer.
Transformed cancer cell-lines RNA-seq database Hi, I am trying to find a database which has RNA-seq data for cancer cell-lines ... I know encode has RNA-seq but those are mostly for cell lines. Also, I looked at SRA in NCBI and was not successful in getting ... Cell Lines: multi-omics network of associations to model precision treatment Modern advances in personalized medicine have used ... Data for comparison between control and treat samples (cells or patients) by single-cell RNA-Seq Hello everyone, I am trying to ...https://www.biostars.org/p/70560/
Browse by UCL Departments and Centres - UCL Discovery
B-CELL GROWTH AND DIFFERENTIATION INDUCED BY SUPERNATANTS OF TRANSFORMED EPITHELIAL-CELL LINES. EUR J IMMUNOL , 16 (8) 1017 - ... REGULATION OF ANTIBODY-PRODUCTION BY AN ANTIGEN-SPECIFIC EBV-TRANSFORMED B-LYMPHOBLASTOID CELL-LINE - EFFECT OF HIGH-DOSE ... ANTIGEN-SPECIFIC SUPPRESSION OF HUMAN-ANTIBODY RESPONSES BY ALLOGENEIC T-CELLS .2. CELL-INTERACTIONS INVOLVED IN THE GENERATION ... A P-31 NUCLEAR-MAGNETIC-RESONANCE STUDY OF ITS REGULATION AND POSSIBLE ROLE IN CONTROLLING CELL-DIFFERENTIATION. J CELL SCI , ...http://discovery.ucl.ac.uk/view/UCL/IC/1986.type.html
Adventitial Gene Transfer of Recombinant Endothelial Nitric Oxide Synthase to Rabbit Carotid Arteries Alters Vascular...
Graham FL, Smiley J, Russell WC, Nairn R. Characteristics of a human cell line transformed by human adenovirus type 5. J Gen ... 16 293 cells are human embryonic kidney carcinoma cells that have been transformed with the left end of human adenovirus type 5 ... Busse R, Mulsch A. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEBS Lett. 1990;275:87-90. ... The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980;288:373-376 ...http://circ.ahajournals.org/content/96/7/2254
2ot0 - Proteopedia, life in 3D
Defective actin polymerization in EBV-transformed B-cell lines from patients with the Wiskott-Aldrich syndrome. J Pathol. 1998 ... Variable expression of WASP in B cell lines of Wiskott-Aldrich syndrome patients. J Immunol. 1997 May 1;158(9):4021-5. PMID: ... Absence of expression of the Wiskott-Aldrich syndrome protein in peripheral blood cells of Wiskott-Aldrich syndrome patients. ...http://proteopedia.org/wiki/index.php/2ot0
The Rb7 Matrix Attachment Region Increases the Likelihood and Magnitude of Transgene Expression in Tobacco Cells: A Flow...
A) Mean GFP fluorescence per cell in cell lines transformed by each of the vectors (data from both GFP positive cells and GFP ... expressing cells in cell lines transformed with MGFPM had a higher average level of green fluorescence than those transformed ... 30 cell lines per T-DNA construct for ∼270 cell lines for all three replicates. Average GFP expression across all lines for ... the percentage of GFP negative cells was determined for each cell line. The averages of these percentages for all cell lines of ...http://www.plantcell.org/content/17/2/418
Towards explaining "unexplained hyperferritinemia" | Haematologica
In EBV-transformed cell lines from patients the ferritin content was normal, excluding an increased synthesis. The authors ... is due to mutant proteins that are not correctly targeted to the cell surface and is characterized by macrophage iron ... due to mutant ferroportins that reach the cell surface but are resistant to hepcidin-induced internalization,7 is characterized ...http://www.haematologica.org/content/94/3/307.full
Oncology/Anti-Cancer | Page 4 | Cranberry Institute
Various reports have also demonstrated its potential for inhibiting in vitro growth of transformed cell lines. Here we show ... and other tumor cell lines. In HT-29 and HCT116 colon tumor cell lines, cranberry proanthocyanidins (PACs) and ursolic acid ... Apoptosis is likely to play a role in limiting tumor cell proliferation. In HT-29 and HCT116 colon tumor cell lines treated ... Moreover, PAC (50 microg/mL) significantly inhibited acid-induced cell proliferation of SEG-1 cells. PAC treatment induced cell ...https://www.cranberryinstitute.org/cranberry-health-research/library/category/oncologyanti-cancer?page=3
Distinct mechanical behavior of HEK293 cells in adherent and suspended states [PeerJ]
Unlike normal stromal and cancer cells, the surface stiffness of adherent HEK293 cells was very low, but increased after cell ... Cancer cells possessed specific mechanical and actin cytoskeleton features that were distinct from normal stromal cells in ... Thus, with respect to their special cell-surface mechanical features, HEK293 cells could be categorized into a new class ... cells to perturbation of the actin cytoskeleton resembled that of adherent cancer cells and suspended normal stromal cells. ...https://peerj.com/articles/1131/
JCI - The role of HIV integration in viral persistence: no more whistling past the proviral graveyard
The EBV-transformed cell line Raji is a well-described B cell line with substantial growth potential. DNA analyses revealed ... High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. ... In shock and kill strategies, LRAs induce HIV by activating infected, quiescent T cells. These cells presumably undergo cell ... In T cells, BACH2 contributes to T cell homeostasis (106, 107). In transgenic mouse models, loss of BACH2 was associated with ...https://jci.org/articles/view/80564
A novel fragile X syndrome mutation reveals a conserved role for the carboxy‐terminus in FMRP localization and function | EMBO...
Culture and treatment of EBV‐transformed lymphoblastoid cell lines. EBV‐transformed lymphoblastoid cell lines were generated ... Cell culture and transfection experiments. Human embryonic kidney (HEK) 293T cells and human neuroblastoma SH‐SY5Y cells were ... transformed lymphocyte cells derived from the patient's blood samples. Patient cells showed a ˜60% decrease in FMR1 mRNA ... In line with our previous observations, we did not detect FMRP in the nucleus of cells expressing GFP‐FMR1G‐ins[Ct revert] (Fig ...http://embomolmed.embopress.org/content/early/2015/02/17/emmm.201404576
"A monoclonal antibody reactive with a 40-kDa molecule on fetal thymocy" by Dancella M. Fernandes, Allison Michelle Baird et al.
To identify functional molecules on this cell line, we screened for mAbs that could block its proliferation. A hamster mAb, ... or bone marrow cells or on splenic LPS-activated B cells or Con A-activated T cells. The Ab immunoprecipitated a 40-kDa ... The DMF10 62.3 mAb stained a number of immortalized murine and human cell lines and, where tested, blocked their proliferation ... The data suggest that the molecule recognized by DMF62.3 is a novel cell surface molecule that may be involved in cell ...https://escholarship.umassmed.edu/oapubs/1136/
"Screening of HIV-1 Env glycoproteins for the ability to raise neutrali" by Joan F. L. Richmond, Farah Mustafa et al.
Neutralizing antibodies were assayed against two T-cell-line-adapted viruses (MN and IIIb), two non-syncytium-inducing (NSI) ... a prototypic T-cell-line-adapted virus), have been screened for their ability to elicit neutralizing antibody to HIV-1. Rabbits ... AIDS Vaccines; Animals; Biolistics; Cell Line, Transformed; Female; Gene Products, env; Genetic Vectors; HIV Antibodies; HIV ... a prototypic T-cell-line-adapted virus), have been screened for their ability to elicit neutralizing antibody to HIV-1. Rabbits ...https://escholarship.umassmed.edu/gsbs_sp/1043/
ORBi: Browsing ORBi
... four stably transfected cell lines were used in cell-based luciferase reporter gene assays: three lines were transformed with ... The fourth is a patented cell line transformed with a different construct: H4IIE DR-CALUX®. Both H4IIE cells were compared for ... In addition, BEN clearly provoked an ER agonistic activity in a human oestrogen sensitive reporter cell line. All these results ... In rat cells, this synergy occurred when cells were exposed to flavonoids and contaminant for 6h, while it was observed in ...http://orbi.ulg.ac.be/browse?type=author&value=Larondelle%2C+Yvan
KEGG SSDB Best Search Result: cpz:CpPAT10 0461
rbb:108529704 MCF.2 cell line derived transforming sequ K20685 1016 103 ( -) 29 0.319 116 ,-, 1 rse:F504_3501 hypothetical ... cell:CBR65_07475 isocitrate dehydrogenase (NADP(+)) K00031 741 3154 ( -) 725 0.631 737 ,-, 1 nme:NMB0920 isocitrate ... bhd:BHYOB78_04310 cell surface protein 436 115 ( -) 32 0.435 62 ,-, 1 bhy:BHWA1_02382 variable surface protein VspH 436 115 ... bka:AH68_01540 cell division protein 492 101 ( -) 29 0.307 114 -, 1 bna:106348767 phosphoinositide phosphatase SAC2-like 796 ...http://www.kegg.jp/ssdb-bin/ssdb_best?org_gene=cpz:CpPAT10_0461
293T TRANSFECTION KIT - Gentaur.com
Technique CV40 transformed cell line or 293tsA1609neo from human kidney 293 cells delivered as 1. ... Human RPS4P4 CRISPR Knock Out Cell Line Suppplier: ABM CrispR. Price: 6 580.64 USD ... API5L1 3'UTR GFP Stable Cell Line Suppplier: ABM microrna. Price: 2 459.97 USD ... TEX21P 3'UTR Luciferase Stable Cell Line Suppplier: ABM microrna. Price: 2 459.97 USD ...https://gentaur.com/prod/293t-transfection-kit/101-biosystem/1924221618
JCI - YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation
... indicates that YAP promotes cell proliferation and glycolysis by upregulating GLUT3 expression in transformed cell lines. In ... Cell growth assay and cell cycle analysis. Cell proliferation was measured using the Cell Counting Kit-8 reagent (CCK-8, ... including cell-cell contact, cell polarity, mechanical cues, secreted mitogens, and cellular metabolic status (6, 8-10), which ... To discriminate dead cells, cells were stained with DAPI (Sigma-Aldrich) and cell sorting was performed with FACSAriaII (BD ...https://jci.org/articles/view/93825
Human Papillomaviruses (IARC Summary & Evaluation, Volume 64, 1995)
... although some experimental findings show that HPV-immortalized cell lines can be transformed by segments of the herpes simplex ... In several HPV-positive cervical carcinoma cell lines of human origin, the malignant phenotype has been shown to depend on the ... those with HIV infection or those with inherited T-cell immunodeficiencies) further supports a role for CD4+ cells in the ... Seroreactive and T-cell epitopes of HPV proteins have been identified using a variety of techniques. In most instances, it is ...http://www.inchem.org/documents/iarc/vol64/hpv.html
Joseph (Joe) Lipsick | Stanford Medicine Profiles
This system enabled us to establish and purify c-myb expressing variants of the v-myb transformed chicken monoblast cell line ... c-Myb-transformed myelomonocytic cells display a different phenotype than cells transformed by v-MybAMV or other Myb mutants. c ... We have also found that, in contrast to normal or v-myb-expressing AMV-transformed CNR cells, c-Myb-transformed cells express ... We have now established lymphoma lines of null cells, B-cells, and T-cells. Lymphoma development is preceded by the secretion ...https://med.stanford.edu/profiles/joseph-lipsick
Limiting deoxynucleoside triphosphate concentrations emphasize the processivity defect of lamivudine-resistant variants of...
However, no replication defect is apparent for these two mutants in the transformed T-cell line SupT1. One obvious difference ... The RT proteins were either isolated from virions produced by primary and transformed cell types or expressed as recombinant ... Primary cells have a much smaller dNTP pool, and this cellular condition may emphasize the processivity defect of the codon 184 ... Alternatively, cell-specific cofactors that influence the process of reverse transcription may exist. Such accessory factors ...https://aac.asm.org/content/41/11/2484
DFG - Deutsche Forschungsgemeinschaft - Priority Programme 1463: 'Epigenetic Regulation of Normal Hematopoiesis and its...
... represented by cell line models and primary transformed human cells ... solid tumours (animal models, cell lines and primary tumours). The following research questions should also be excluded, unless ... What lies ahead is to identify and manipulate specific epigenetic mechanisms that are at work in cancer cells and to explore ... enzymatic mechanisms of normal and transformed myeloid epigenesis. *RNA methylation (insofar as it relates to gene expression) ...http://www.dfg.de/foerderung/info_wissenschaft/2009/info_wissenschaft_09_46/index.html
3 Overview of Vitamin D | Dietary Reference Intakes for Calcium and Vitamin D | The National Academies Press
... non-transformed prostate epithelial cell line, RWPE1. BMC Genomics 11: 26.. Kull, M., Jr., R. Kallikorm, A. Tamm and M. Lember ... in antigen-presenting cells, in macrophages and monocytes, and in cytotoxic T cells. Gene array studies in many cells and ... Inhibitory effect of 220-oxa-1,25-dihydroxyvitamin D3 on the proliferation of pancreatic cancer cell lines. Gastroenterology ... Vitamin D-metabolism in the human breast cancer cell line MCF-7. Anticancer Research 26(4A): 2755-9. ...https://www.nap.edu/read/13050/chapter/5
293 cell line slides - Nordic Biosite
293 (kidney; transformed with adenovirus 5 DNA). Human 293 cells were cultured in Minimum Essential Medium (Eagle) with 2 mM L- ... The 293 cells were fixed in 4% paraformaldehyde and arrayed on a 12-well (5 mm) adhesive coated slide, with each wellis surface ... A follow-up heat dehydration process was done to ensure the attachment of 293 cells and the stability of cellular proteins. ... 293 cell slide is provided for immunocytochemical analysis of protein and protein-protein interaction. Procedures for ...https://nordicbiosite.com/product/GTX25524/293-cell-line-slides
Human embryonic kidney cells, SEM - Stock Image G442/0328 - Science Photo Library
The HEK cell line has been transformed by the insertion of adenovirus DNA (deoxyribonucleic acid) to continuously grow in ... The cells are easy to work with and so widely used in biological research. HEK cells were transformed by Frank Graham in 1970 ... Coloured scanning electron micrograph (SEM) of human embryonic kidney (HEK) cells in culture. ... cell line, cells, coloured, culture, cultured, embryo, false-coloured, frank graham, hek cell, human embryonic kidney cell, ...http://www.sciencephoto.com/media/214529/view/human-embryonic-kidney-cells-sem