Circulating cell-derived microparticles have been shown to have pro-inflammatory, pro-coagulant and endothelial function- ... Levels of platelet-derived and leukocyte-derived microparticles were also significantly higher in patients with OSA (2,267 ( ... and endothelial cell-derived microparticles were measured by flow cytometry. In patients with OSA, median (interquartile range ... Endothelial cell-derived microparticle levels were similar in patients with OSA compared with control subjects (13 (8-25) ...
Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 ... Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 ... Oat-enriched diet reduces inflammatory status assessed by circulating cell-derived microparticle concentrations in type 2 ...
"Macrophages discriminate glycosylation patterns of apoptotic cell-derived microparticles". The Journal of Biological Chemistry ... Although most cells are capable of phagocytosis, some cell types perform it as part of their main function. These are called ... One of the features of an apoptotic cell is the presentation of a variety of intracellular molecules on the cell surface, such ... Phagocytosis (from Ancient Greek φαγεῖν (phagein) to eat, and κύτος (kytos) cell) is the process by which a cell uses its ...
In HL-60 leukaemia cells, di-GA activated caspase 3 and dose-dependently induced apoptosis. It further inhibited cell-cycle ... cell-cycle arrest and disruption of cancer cell-induced lymphendothelial disintegration. ... Furthermore, di-GA inhibited the generation of lymphendothelial gaps by cancer cell spheroid-secreted lipoxygenase metabolites ... ribonucleotide reductase activity by 14C-cytidine incorporation into nascent DNA and cell-cycle distribution by FACS. Apoptosis ...
Cell Communication * Cell-Derived Microparticles* * Exosomes* / metabolism * Extracellular Vesicles* / chemistry * Humans * ... from human prostate cancer cells. These findings provide the basis for a better colloidal description of EV samples, might help ... Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway. ...
8, 16] Endothelial cells, blood platelets, or leukocytes shed microparticles upon activation and cell apoptosis (normal ... Microparticles, 0.1- to 1-μm diameter vesicular structures [14] derived from vascular walls, have been found to increase 3.4 ... Pontier JM, Gempp E, Ignatescu M. Blood platelet-derived microparticles release and bubble formation after an open-sea air dive ... The microparticles may result from oxidative stress (see the next paragraph). [15] They appear to activate neutrophils and ...
Breast Cancer-Derived Microparticles Reduce Cancer Cell Adhesion, an Effect Augmented by Chemotherapy Autoren: Dvir Shechter, ... Veröffentlicht in: Cells, Issue 9/10, 2020, Page(s) 2269, ISSN 2073-4409. Herausgeber: Cells DOI: 10.3390/cells9102269. ... Microparticles from tumors exposed to radiation promote immune evasion in part by PD-L1 Autoren: Michael Timaner, Ruslana ... The multifaceted role of mesenchymal stem cells in cancer Autoren: Michael Timaner, Kelvin K Tsai, Yuval Shaked Veröffentlicht ...
Increased procoagulant cellderived microparticles (C‐MP) in splenectomized patients with ITP. Thromb Res 2008; 122: 599-603. ... Supportive red cell transfusions, antifibrinolytic therapy with tranexamic acid (up to 1000 mg intravenous three times a day) ... Infusion reactions are more likely to occur with standard dose or 1 g rituximab infusions, and successful B‐cell depletion is ...
Measuring circulating cell-derived microparticles. J Thromb Haemost 2004;2:1842-3.doi:10.1111/j.1538-7836.2004.00936.x. ... neutrophil derived (CD66b+), monocyte derived (CD14+) and endothelial cell derived (CD144+). Prothrombotic potential will be ... A flow cytometric method for characterization of circulating cell-derived microparticles in plasma. J Extracell Vesicles 2014;3 ... T cells will be categorised as helper (CD3+CD4+) cytotoxic (CD3+CD8+) and regulatory (CD4+CD25+CD127-) T cells. B Cells will be ...
Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles. Blood 2008, 112, 2512-2519. [ ... Matrix metalloproteinase activity inactivates the cxc chemokine stromal cell-derived factor-1. J. Biol. Chem. 2001, 276, 43503- ... Cell Rep. 2017, 19, 1572-1585. [Google Scholar] [CrossRef] [PubMed]. *Marques, P.E.; Oliveira, A.G.; Pereira, R.V.; David, B.A ... Cell Biol. 2004, 16, 558-564. [Google Scholar] [CrossRef][Green Version]. *Overall, C.M.; McQuibban, G.A.; Clark-Lewis, I. ...
Yeast Cells-Derived Hollow Core/Shell Heteroatom-Doped Carbon Microparticles for Sustainable Electrocatalysis ... Coconut coir-derived nanocellulose as an efficient adsorbent for removal of cationic dye safranin-O: a detailed mechanistic ... Coconut Coir derived Nanocellulose as an Efficient Adsorbent for Removal of Cationic Dye Safranine -O: A detailed Mechanistic ... Hydrazine is often regarded as one of the most appealing fuels for fuel cells due to its high energy content, and also because ...
The primary goal of this study is to elucidate how the basic properties of MSC derived EVs can be exploited for function- ... The primary goal of this study is to elucidate how the basic properties of MSC derived EVs can be exploited for function- ... Overall, the results presented in this study show a common mechanism of endocytosis for MSC EVs across different cell types and ... Overall, the results presented in this study show a common mechanism of endocytosis for MSC EVs across different cell types and ...
Mause SF, Weber C: Microparticles: protagonists of a novel communication network for intercellular information exchange. Circ ... Mesenchymal Stem Cell-Derived Exosomes Promote Fracture Healing in a Mouse Model. Stem Cells Transl Med 2016; 5: 1620-1630. ... Adipose tissue-derived mesenchymal stem cells. AD-MSC were obtained from the adipose tissue of 10 non-obese donors (4 men and 7 ... Zhang S, Chu WC, Lai RC, Lim SK, Hui JH, Toh WS: Exosomes derived from human embryonic mesenchymal stem cells promote ...
Also, we found that most of these correlations were absent in misshapen red blood cells that have an inborn defect in the ... Many if not all of these processes depend on the organization of the red blood cell membrane that enables the complex, dynamic ... As a first step, we correlated a number of deformability and aggregation parameters in red blood cells from healthy donors, ... Since this interaction is most prominent during red blood cell aggregation and deformation, we measured these properties in a ...
... being involved in the transmission of biological signals between cells in both prokaryotes and higher eukaryotes to regulate a ... Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells. Exp. ... Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats. J. Cell. Mol. Med. 14, 1605 ... Microvesicles derived from human bone marrow mesenchymal stem cells inhibit tumor growth. Stem Cells Dev. 22, 758-771 (2012). ...
... microparticles within human embryonic stem cell derived aggregates. Journal of controlled release : official journal of the ... 2D and 3D cell culture (including embryonic stem cell, mesenchymal stem cells and primary tissue-derived cells), holographic ... In vitro differentiation and in vivo mineralization of osteogenic cells derived from human embryonic stem cells Tissue ... I am involved in a number of projects to investigate the influence of 3-D cell-cell, cell-scaffold/matrix interactions and ...
Recent studies have focused on the role of microparticles (MPs) in SDB disorders. Cell-derived MPs are microvesicles of 0.05 to ... Characterization of MPs provides a fine-grained and quantitative measure of cell-to-cell communication. Case-control and ... experimental studies indicate that platelet-, endothelium- and leukocyte-derived MP levels are increased in SDB and induce ... 1 micrometers, released through exocytic budding of the plasma membrane, following stimulation of different cell types. ...
Brodsky SV, Zhang F, Nasjletti A and Goligorsky MS: Endothelium-derived microparticles impair endothelial function in vitro. Am ... Exosomal STAT1 derived from high phosphorus‑stimulated vascular endothelial cells induces vascular smooth muscle cell ... Bone marrow mesenchymal stem cell-derived exosomes alleviate high phosphorus-induced vascular smooth muscle cells calcification ... Cai M, Shi Y, Zheng T, Hu S, Du K, Ren A, Jia X, Chen S, Wang J and Lai S: Mammary epithelial cell derived exosomal MiR-221 ...
... microparticles by bone marrow-derived phagocytosing cells.. Acta Biomater; 2018-10-15; 80(): 352-363; doi:10.1016/j.actbio. ... Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles and Their Potential as Novel Immunomodulatory Therapeutic Agents. ... Neuroendocrine cells of the prostate derive from the neural crest.. J Biol Chem; 2017-02-03; 292(5): 2021-2031; doi:10.1074/jbc ... Infection of B Cell Follicle-Resident Cells by Friend Retrovirus Occurs during Acute Infection and Is Maintained during Viral ...
Upon activation, platelets release plasma-membrane derived microparticles (PMPs) exposing phosphatidylserine (PS) on their ... Cell and Molecular Biology. in Journal of Biological Chemistry. volume. 291. issue. 20. pages. 10586 - 10601. publisher. ... Upon activation, platelets release plasma-membrane derived microparticles (PMPs) exposing phosphatidylserine (PS) on their ... The Gas6-Axl Interaction Mediates Endothelial Uptake of Platelet Microparticles. *Mark. Happonen, Kaisa E LU ; Tran, Sinh LU ; ...
... and endothelial cell dysfunction resulting in untoward pregnancy outcomes. In this review, we detail these effects and their ... E. Biró, K. N. Sturk-Maquelin, G. M. Vogel et al., "Human cell-derived microparticles promote thrombus formation in vivo in a ... Vascular injury initiates clotting when plasma-derived factor VII binds to the extracellular domain of perivascular cell ... These MPs are small vesicles released from injured or activated cells, primarily leukocytes and endothelial cells [58, 69]. TF- ...
Levels of microparticles, tiny molecule-filled sacs shed from cells, were altered in the bloodstream of adults with systemic ... Elevated microparticles derived from blood-clotting platelets were associated with disease-related antibodies and longer ... which contain cell type-specific components. Mostly shed from platelets, white blood cells, and endothelial cells, MPs have ... Microparticles shed from cells may be linked with SSc: Study 7/5/2023 ...
Collagen-induced generation of platelet-derived microparticles in whole blood is dependent on ADP released from red blood cells ... Expression of P2Y receptors in cell lines derived from the human lung. Communi, D., Paindavoine, P., Place, G.A., Parmentier, M ... J. Physiol., Cell Physiol. (2003) [Pubmed]. *ATP P2 receptors and regulation of bone effector cells. Gallagher, J.A. Journal of ... Cell Biol. (1997) [Pubmed]. *ATP receptor regulation of adenylate cyclase and protein kinase C activity in cultured renal LLC- ...
... microparticles within human embryonic stem cell derived aggregates.. Journal of Controlled Release, 168(1) pp. 18-27. ... Improved delivery of PLGA microparticles and microparticle-cell scaffolds in clinical needle gauges using modified viscosity ... A biomaterials approach to influence stem cell fate in injectable cell-based therapies.. Stem Cell Research & Therapy, 9(1), ... Extracellular matrix-derived hydrogels for dental stem cell delivery.. Journal of Biomedical Materials Research Part A, 105(1) ...
As a cell-free therapy, MSCs-derived extracellular vesicles (MSC-EVs) have some preponderance on stability, immune rejection, ... EVs play a pivotal role in regulating the biological functions of both periodontal tissue cells and immune cells, as well as ... Various cells release lipid-enclosed particles known as extracellular vesicles (EVs), which are rich in bioactive substances. ... due to the unique characteristics of mesenchymal stem cells (MSCs), they have become the focus of attention and may be the most ...
The Functional Heterogeneity of Neutrophil-Derived Extracellular Vesicles Reflects the Status of the Parent Cell CELLS Kolonics ... mainly medium-sized microvesicles/microparticles. According to published data, authors have reached a consensus on the physical ... listing their effects according to the triggering agents and target cells. We summarize the presence of neutrophil-derived EVs ... Studying bone marrow derived neutrophils of genetically modified animals we verify that the involved complement receptor is CR3 ...
... composed by TKhAMSCs and a scaffold made of polylactic acid microparticles and cell-derived extracellular matrix deposited by ... Cell Adhesion/drug effects, Cell Differentiation/drug effects, Cell Proliferation/drug effects, Cell Shape/drug effects, Cells ... cell-derived matrix, cultispher® s, microtissue, poly-lactic acid microcarriers, Angiogenesis, Cell-derived matrix, Cultispher ... JTD Keywords: 3d cell-derived matrices, adipose mesenchymal stem cells, collagen matrix, colorectal adenocarcinoma, ...
Functional translation of total RNA packaged in microparticles shed from multidrug resistant cancer cells. Lu, JF; Pokharel, D ... 4 Cell-Derived Microparticles * 4 Drug Resistance, Multiple *. next > Date issued. * 34 2010 - 2020 ...
Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory ... Mast cell-derived exosomes activate endothelial cells to secrete plasminogen activator inhibitor type 1. Arterioscler Thromb ... Atheroprotective conversation between endothelial cells and even muscles cells through miRNAs. Character cell biology 2012 14 [ ... ICAM-1 on exosomes from older dendritic cells is crucial for effective naive T-cell priming. Bloodstream 2005 106 [PubMed] 59 ...
Fern Tablin, VMD, PhD, Department of Anatomy, Physiology and Cell Biology, University of California, Davis, 4206 VM3A, Davis, ... These findings demonstrate a systemic proinflammatory and procoagulant response to inhalation of environmentally derived fine ... of platelets by thrombin resulted in up-regulation of LAMP-1 expression in CAPs-exposed animals and an increased microparticle ... The authors evaluated blood cell parameters and markers of platelet activation in mice exposed to concentrated ambient ...