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*  MCF2L Gene - GeneCards | MCF2L Protein | MCF2L Antibody
MCF.2 Cell Line Derived Transforming Sequence Like, including: function, proteins, disorders, pathways, orthologs, and ... MCF.2 cell line derived transforming sequence-like (A2A2X3_HUMAN). *MCF.2 cell line derived transforming sequence-like (A2A2X4_ ... MCF.2 cell line derived transforming sequence-like (A2A640_HUMAN). *MCF.2 cell line derived transforming sequence-like (B7ZBJ8_ ... MCF2L (MCF.2 Cell Line Derived Transforming Sequence Like) is a Protein Coding gene. Diseases associated with MCF2L include ...
https://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=23263
*  RECK Gene - GeneCards | RECK Protein | RECK Antibody
It is undetectable in tumor-derived cell lines and oncogenically transformed cells. ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RECK Gene. ... mRNA expression in embryonic tissues and stem cells from LifeMap Discovery. *span" data-trigger="SectionLoaded"> Dermis ( ... In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key ...
https://www.genecards.org/cgi-bin/carddisp.pl?gene=RECK
*  MYEOV Gene - GeneCards | MYEOV Protein | MYEOV Antibody
Concurrent activation of a novel putative transforming gene, myeov, and cyclin D1 in a subset of multiple myeloma cell lines ... The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58 ... MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell ... No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=MYEOV
*  TGFA Gene - GeneCards | TGFA Protein | TGFA Antibody
Transforming Growth Factor Alpha, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - ... Cell Line Molecular function for TGFA Gene. GENATLAS Biochemistry: transforming growth factor,alpha,17kDa,expressed in ... Transforming growth factor alpha: Secreted, extracellular space.. *P01135-TGFA_HUMAN. Protransforming growth factor alpha: Cell ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TGFA Gene. ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=TGFA
*  DGCR6 Gene - GeneCards | DGCR6 Protein | DGCR6 Antibody
Increased levels in several tumor cell lines, including lung and colon adenocarcinomas and mammary carcinomas. Strongly induced ... in Burkitts lymphoma and lymphocytes transformed by EBV. *DGCR6_HUMAN,Q14129 ... May play a role in neural crest cell migration into the third and fourth pharyngeal pouches. *DGCR6_HUMAN,Q14129 ... No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential ...
https://www.genecards.org/cgi-bin/carddisp.pl?gene=DGCR6
*  KMT2E Gene - GeneCards | KMT2E Protein | KMT2E Antibody
Not detected on circulating cells from healthy individuals, but is expressed on a large panel of tumor and transformed cells ( ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for KMT2E Gene. ... Also acts as an important cell cycle regulator, participating in cell cycle regulatory network machinery at multiple cell cycle ... Also acts as an important cell cycle regulator, participating in cell cycle regulatory network machinery at multiple cell cycle ...
https://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=55904
*  SLC39A5 Gene - GeneCards | S39A5 Protein | S39A5 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for SLC39A5 Gene ... Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates ... mRNA expression in embryonic tissues and stem cells from LifeMap Discovery. *span" data-trigger="SectionLoaded"> Intestine ( ... May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=SLC39A5
*  COMP Gene - GeneCards | COMP Protein | COMP Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for COMP Gene. ... Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the ... Articular chondrocyte-like cells(Sternberg H et. al. 2012) * HyStem+TGFbeta3+GDF5-induced 4D20.8 cells(Sternberg H et. al. 2012 ... Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=COMP
*  ECI2 Gene - GeneCards | ECI2 Protein | ECI2 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ECI2 Gene. ... Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference ... Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference ... mRNA expression in embryonic tissues and stem cells from LifeMap Discovery. *span" data-trigger="SectionLoaded"> Brain (Nervous ...
https://www.genecards.org/cgi-bin/carddisp.pl?id=14601&id_type=hgnc&search=14601
*  TGFBI Gene - GeneCards | BGH3 Protein | BGH3 Antibody
Transforming Growth Factor Beta Induced, including: function, proteins, disorders, pathways, orthologs, and expression. ... Cell Line Molecular function for TGFBI Gene. GENATLAS Biochemistry: transforming growth factor B induced gene,keratoepithelin, ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TGFBI ... The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=TGFBI
*  ELF3 Gene - GeneCards | ELF3 Protein | ELF3 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ELF3 ... Note=Localizes to the cytoplasm where it has been shown to transform MCF-12A mammary epithelial cells via a novel cytoplasmic ... Also transiently expressed and localized to the nucleus where it induces apoptosis in non-transformed breast epithelial cells ... span" data-trigger="SectionLoaded"> Epithelial Cells (Uncategorized) * Induced hepatocyte-like cells(Sekiya S et. al. 2011) ...
https://www.genecards.org/cgi-bin/carddisp.pl?gene=ELF3
*  MIR15B Gene - GeneCards | MIR15B RNA Gene
negative regulation of cell proliferation. IGI. 22139073. GO:0030512. negative regulation of transforming growth factor beta ... Cell Line Products. * GenScript Custom overexpressing Cell Line Services for MIR15B * Browse ESI BIO Cell Lines and PureStem ... miR-15b Inhibits the Progression of Glioblastoma Cells Through Targeting Insulin-like Growth Factor Receptor 1. (PMID: 27896672 ... No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=MIR15B
*  CBL Gene - GeneCards | CBL Protein | CBL Antibody
Cell Line Molecular function for CBL Gene. GENATLAS Biochemistry: Cas-Br-M (murine) ecotropic retroviral transforming sequence, ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CBL ... Cell membrane. Note=Colocalizes with FGFR2 in lipid rafts at the cell membrane.. *P22681-CBL_HUMAN ... Listeria monocytogenes entry into host cells. Listeria monocytogenes entry into host cells ...
http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=867
*  C1orf35 Gene - GeneCards | MMTA2 Protein | MMTA2 Antibody
Cloning and sequence analysis of tumor-associated gene hMMTAG2 from human multiple myeloma cell line ARH-77. (PMID: 12545221) ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for C1orf35 Gene ... No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression ... This gene is overexpressed in Lung (19.6), Peripheral blood mononuclear cells (14.9), CD4 Tcells (6.9), and Pancreatic juice ( ...
https://www.genecards.org/cgi-bin/carddisp.pl?gene=C1orf35
*  ECI1 Gene - GeneCards | ECI1 Protein | ECI1 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ECI1 ... Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. *ECI1_HUMAN,P42126 ... Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. ... No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=ECI1
*  TEX14 Gene - GeneCards | TEX14 Protein | TEX14 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TEX14 Gene. ... blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: ... Note=Detected in the intercellular bridges that connect male germ cell daughter cells after cell division. {ECO:0000250}.. * ... span" data-trigger="SectionLoaded"> Germ Cells (Reproductive System) * Primordial germ-like cells(West JA et. al. 2006) ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=TEX14
*  BMP8B Gene - GeneCards | BMP8B Protein | BMP8B Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for BMP8B Gene. ... This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this ... span" data-trigger="SectionLoaded"> It affects the following cells: * Epiblast *Intraembryonic Epiblast Cells (Epiblast) ... span" data-trigger="SectionLoaded"> Epithelial Cells * Mature Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium ...
http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=656
*  BMP8A Gene - GeneCards | BMP8A Protein | BMP8A Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BMP8A Gene. ... This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this ... span" data-trigger="SectionLoaded"> Epithelial Cells * Fetal Inner Root Sheath Cells Inner Root Sheath ... mRNA expression in embryonic tissues and stem cells from LifeMap Discovery. *span" data-trigger="SectionLoaded"> Hair ( ...
https://www.genecards.org/cgi-bin/carddisp.pl?gene=BMP8A
*  HTRA1 Gene - GeneCards | HTRA1 Protein | HTRA1 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for HTRA1 Gene. ... It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of ... Cell membrane. Secreted. Cytoplasm, cytosol. Note=Predominantly secreted (PubMed:15208355). Also found associated with the ... No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression ...
https://www.genecards.org/cgi-bin/carddisp.pl?gene=HTRA1
*  RAB38 Gene - GeneCards | RAB38 Protein | RAB38 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RAB38 Gene. ... mRNA expression in embryonic tissues and stem cells from LifeMap Discovery. *span" data-trigger="SectionLoaded"> Blood ( ... span" data-trigger="SectionLoaded"> Mesenchymal Stem Cells (Uncategorized) * Umbilical cord blood-derived mesenchymal stem ... Cell membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome ...
https://www.genecards.org/cgi-bin/carddisp.pl?gene=RAB38&keywords=GH11I088188&prefilter=genomic_location
*  GDF11 Gene - GeneCards | GDF11 Protein | GDF11 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for GDF11 Gene. ... This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this ... span" data-trigger="SectionLoaded"> It affects the following cells: * Paraxial Mesoderm *Paraxial Mesoderm Cells (Trunk ... GDF11 as signaling molecule is secreted from the following cells * Paraxial Mesoderm *Paraxial Mesoderm Cells (Trunk Mesoderm) ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=GDF11
*  RAB17 Gene - GeneCards | RAB17 Protein | RAB17 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RAB17 ... immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor. ISS. --. GO:0006810. transport. ... ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2. ( ... Cell projection, dendrite. Note=May also localize at the basolateral and apical plasma membrane. In neurons, localizes to the ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=RAB17
*  GDF1 Gene - GeneCards | GDF1 Protein | GDF1 Antibody
Cell Line Products. * GenScript Custom overexpressing Cell Line Services for GDF1 * Browse ESI BIO Cell Lines and PureStem ... This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this ... May mediate cell differentiation events during embryonic development. *GDF1_HUMAN,P27539. GENATLAS Biochemistry: growth/ ... Gene Ontology (GO) annotations related to this gene include cytokine activity and transforming growth factor beta receptor ...
https://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=2657
*  BMP3 Gene - GeneCards | BMP3 Protein | BMP3 Antibody
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for BMP3 Gene. ... This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this ... mRNA expression in embryonic tissues and stem cells from LifeMap Discovery. *span" data-trigger="SectionLoaded"> Bone ( ... BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway. (PMID: 20143330) Stewart A ...
https://www.genecards.org/cgi-bin/carddisp.pl?gene=BMP3
*  CAT Gene - GeneCards | CATA Protein | CATA Antibody
B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. *CATA_HUMAN, ... Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) ... Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and ... Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CAT ...
http://www.genecards.org/cgi-bin/carddisp.pl?gene=CAT&interactions=40