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*  Actions and interactions of glucocorticoids and transforming growth factor beta on two related human myeloma cell lines --...
... on two closely related myeloma cell lines, OPM-1 and OPM-2. Earlier studies showed that both cell lines contain glucocorticoid ... Actions and interactions of glucocorticoids and transforming growth factor beta on two related human myeloma cell lines. BH ... Cell Growth & Differentiation, Vol 4, Issue 1 25-30, Copyright © 1993 by American Association of Cancer Research ... These data suggest that the glucocorticoid effect(s) on myeloma cells may be mediated at least in part through modulation of ...
http://cgd.aacrjournals.org/cgi/content/abstract/4/1/25
*  Characterization of epidermal growth factor receptor induction by retinoic acid in a chemically transformed rat liver cell line...
... increases the level of 125I-EGF binding in several clones of the transformed cell lines. One such cell line, GP6ac, which ... Characterization of epidermal growth factor receptor induction by retinoic acid in a chemically transformed rat liver cell line ... expression vary widely among cell lines derived clonally from a chemically transformed population of rat liver epithelial cells ... Retinoic acid (RA), a derivative of vitamin A that stimulates differentiation in a number of embryonal cell lines, ...
http://cgd.aacrjournals.org/cgi/content/abstract/1/9/393
*  CG&D -- Table of Contents (May 1 2000, 11 [5])
Calpain Inhibitor 1 Activates p53-dependent Apoptosis in Tumor Cell Lines Cell Growth Differ 2000 11: 247-253. [Abstract] [Full ... Genistein Regulation of Transforming Growth Factor-. , Epidermal Growth Factor (EGF), and EGF Receptor Expression in the Rat ... Role of p53 in Cell Cycle Regulation and Apoptosis following Exposure to Proteasome Inhibitors Cell Growth Differ 2000 11: 239- ... Cell Growth & Differentiation. Receive this page by email each issue: [Sign up for eTOCs] Contents: May 1 2000, Volume 11, ...
http://cgd.aacrjournals.org/content/vol11/issue5/
*  Inducible transformation of cells from transgenic mice expressing SV40 under lac operon control -- Epstein-Baak et al. 3 (2):...
This report characterizes fibroblast cell lines established from these transgenics that are readily transformed in vitro with ... many areas of cell biology would benefit. Indeed, it would be even more helpful if these cells could subsequently be restored ... Inducible transformation of cells from transgenic mice expressing SV40 under lac operon control. R Epstein-Baak, Y Lin, V ... Cell Growth & Differentiation, Vol 3, Issue 2 127-134, Copyright © 1992 by American Association of Cancer Research ...
http://cgd.aacrjournals.org/cgi/content/abstract/3/2/127
*  Induction of differentiation-regulated transcription factor Oct-6 specifically accompanies major histocompatibility complex...
... relative to Ad5-transformed cells.(ABSTRACT TRUNCATED AT 250 WORDS) HOME. HELP. FEEDBACK. SUBSCRIPTIONS. ARCHIVE. SEARCH. TABLE ... Like MHC class I expression, Oct-6 expression was not affected in already established cell lines expressing Ad12 E1A. The ... only oncogenic Ad12-transformed cells that are derived from primary cell cultures expressed an additional octamer-binding ... However, only Ad12-transformed cells are oncogenic in immunocompetent rodents, an event that requires conserved region 3 (CR3) ...
http://cgd.aacrjournals.org/cgi/content/abstract/6/8/977
*  CG&D -- Table of Contents (September 1 1992, 3 [9])
Functional analyses of albumin expression in a series of hepatocyte cell lines and in primary hepatocytes Cell Growth Differ ... Down-regulation of cytokeratin 14 mRNA in polyoma virus middle T-transformed rat liver epithelial cells Cell Growth Differ 1992 ... Down-regulation of cell cycle control genes by ionizing radiation Cell Growth Differ 1992 3: 637-644. [Abstract] [PDF] TP ... Cell Growth Differ 1992 3: 645-654. [Abstract] [PDF] LJ Gudas Retinoids, retinoid-responsive genes, cell differentiation, and ...
http://cgd.aacrjournals.org/content/vol3/issue9/
*  Activation of hepatic stem cell compartment in the rat: role of transforming growth factor alpha, hepatocyte growth factor, and...
Identification of a Bipotential Precursor Cell in Hepatic Cell Lines Derived from Transgenic Mice Expressing Cyto-Met in the ... of epidermal growth factor and transforming growth factor-beta induces novel phenotypic changes in mouse liver stem cell lines ... Activation of hepatic stem cell compartment in the rat: role of transforming growth factor alpha, hepatocyte growth factor, and ... cells. Here, we examine the earliest stages of stem cell activation in rat liver using an experimental model involving ...
http://cgd.aacrjournals.org/cgi/content/abstract/4/7/555
*  Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein --...
Differential expression of the ccn3 (nov) proto-oncogene in human prostate cell lines and tissues. Mol. Pathol., August 1, 2001 ... Transforming Growth Factor-{beta}-Stimulated Connective Tissue Growth Factor Expression during Corneal Myofibroblast ... Connective Tissue Growth Factor Induces Apoptosis in Human Breast Cancer Cell Line MCF-7. J. Biol. Chem., December 24, 1999; ... Identification of rCop-1, a New Member of the CCN Protein Family, as a Negative Regulator for Cell Transformation. Mol. Cell. ...
http://cgd.aacrjournals.org/cgi/content/abstract/2/5/225
*  Activation of p34cdc2 coincident with taxol-induced apoptosis -- Donaldson et al. 5 (10): 1041 -- Cell Growth & Differentiation
Apoptosis as a Predictor of Paclitaxel-induced Radiosensitization in Human Tumor Cell Lines. Clin. Cancer Res., September 1, ... Cdc2 and Cdk2 Kinase Activated by Transforming Growth Factor-{beta}1 Trigger Apoptosis through the Phosphorylation of ... cell cycle progression appeared requisite for cell death. Taxol treatment of G0/G1 or G2/M cells clearly leads to a block of ... Arsenic Trioxide Produces Polymerization of Microtubules and Mitotic Arrest before Apoptosis in Human Tumor Cell Lines. Mol. ...
http://cgd.aacrjournals.org/cgi/content/abstract/5/10/1041?ijkey=c747979b19f6ff5c756fa761b14b1339184e3ef2&keytype2=tf_ipsecsha
*  PCTAIRE-1: Characterization, Subcellular Distribution, and Cell Cycle-dependent Kinase Activity -- Charrasse et al. 10 (9): 611...
PCTAIRE-1 is expressed across the entire panel of cell lines that we have examined. The fact that transformed cells display ... Jurkat cells, Lane 1; COS-7 cells, Lane 2; Hs68 cells, Lane 3; NIH3T3 cells, Lane 4; human lung carcinoma A549 cells, Lane 5; ... 5. Cell cycle-dependent PCTAIRE-1 kinase activity in HeLa cells. HeLa cells were synchronized by a double thymidine block. Cell ... We examined the pattern of PCTAIRE-1 protein expression in a number of normal and transformed cell lines of various origins and ...
http://cgd.aacrjournals.org/cgi/content/full/10/9/611
*  Identification of Epidermal Growth Factor Receptor- Grb2-associated Binder-1-SHP-2 Complex Formation and Its Functional Loss...
... cell line model of neoplastic progression. Specifically, we used asbestos-transformed SHE fibroblasts: the 10W+8 clone, which ... 8 cells. On the other hand, Gab1 was not detected in 10W2T cells, and the EGF-dependent association of SHP-2 with EGFR was also ... Gab1 was detected, and the EGF-dependent formation of the EGFR-Gab1-SHP-2 complex was observed in 10W+8 cells. After cloning ... Cell Growth & Differentiation Vol. 12, 307-318, June 2001. © 2001 American Association for Cancer Research Identification of ...
http://cgd.aacrjournals.org/cgi/content/abstract/12/6/307
*  Preservation of the Myofibroblastic Phenotype of Human Papilloma Virus 16 E6/E7 Immortalized Human Bone Marrow Cells Using the...
Simian virus 40-transformed adherent cells from human long-term marrow cultures: cloned cell lines produced cells with stromal ... and lines (Fig. 5B. , SM-56 cell line; Fig. 5C. , SV40-56 cell line; Fig. 5D. , LTR-9 cell line). The network was mainly ... LTR-9 line P18; Lane E, LTR-9 line P115; Lane F, SV40 56 line P17; Lane G, SV40-56 line P105; Lane H, SM-56 line P30; Lane I, ... for cell lines and at 1 x 104 cells/well for the control pStro1+ cells. At confluence, cells were washed once and fixed for 30 ...
http://cgd.aacrjournals.org/cgi/content/full/12/5/233
*  Transforming growth factor alpha regulation of two zinc finger-containing immediate early response genes in intestine -- DuBois...
Cell Growth & Differentiation, Vol 6, Issue 5 523-529, Copyright © 1995 by American Association of Cancer Research ... The epithelium lining the intestine undergoes rapid and continuous renewal. Growth factors play a role in intestinal epithelial ... In this study, transforming growth factor alpha (TGF alpha) is shown to act as a mitogen and induce the expression of two zinc ... Transforming growth factor alpha regulation of two zinc finger-containing immediate early response genes in intestine. RN ...
http://cgd.aacrjournals.org/cgi/content/abstract/6/5/523
*  Methylation Matters: Modeling a Manageable Genome -- Ordway and Curran 13 (4): 149 -- Cell Growth & Differentiation
... changes in proliferative capacity for a transformed cell to cause malignancy. For example, transformed cells acquire the ... Okano et al. (41) produced embryonic stem cell lines with homozygous null mutations in Dnmt3a and Dnmt3b, separately and in ... demonstrated increased DNA methyltransferase activity in various tumorigenic cell lines relative to nontumorigenic cells. ... Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle. Mol. Cell. Biol., ...
http://cgd.aacrjournals.org/cgi/content/full/13/4/149
*  Expression Profiling of Lineage Differentiation in Pluripotential Human Embryonal Carcinoma Cells -- Houldsworth et al. 13 (6):...
ID expression varies with lineage during differentiation of pluripotential male germ cell tumor cell lines. Cell Tissue Res., ... 1, and then log transformed to give x = log(f'). For each transcript at each time point, the mean of the log-transformed values ... Human EC cell lines provide an excellent model system in which the molecular mechanisms governing cell fate and lineage ... Cell Culture.. Cultures of NT2/D1 cells were maintained in DMEM as described previously (13) . Cells were seeded at 2.5 x 106/ ...
http://cgd.aacrjournals.org/cgi/content/full/13/6/257
*  The Novel Triterpenoid 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid Induces Apoptosis of Human Myeloid Leukemia Cells by a...
Components of the Cell Death Machine and Drug Sensitivity of the National Cancer Institute Cell Line Panel. Clin. Cancer Res., ... Synthetic Triterpenoids Enhance Transforming Growth Factor {beta}/Smad Signaling. Cancer Res., March 15, 2003; 63(6): 1371 - ... A, U-937(left panel) and U-937/Bcl-xL (right panel) cells were treated 5 µM CDDO for 12 and 24 h. Total cell lysates were ... Bianchi, S. G., M. Romani, C. D., Garre, C., and Ravazzolo, R. Terminal erythroid differentiation in the K-562 cell line by 1-ß ...
http://cgd.aacrjournals.org/cgi/content/full/11/5/261
*  Ras- and Mitogen-activated Protein Kinase Kinase-dependent and -independent Pathways in p21Cip1/Waf1 Induction by Fibroblast...
Chatani Y., Tanimura S., Miyoshi N., Hattori A., Sato M., Kohno M. Cell type-specific modulation of cell growth by transforming ... which is lacking in a breast cancer cell line resistant to growth inhibition (33) . Thus, S-phase entry is probably feasible ... and PDGF in NIH 3T3 cells, we analyzed DNA replication of the cells and cell cycle distribution by BrdUrd incorporation and ... Unlike its behavior in epithelial cells, TGF-ß did not regulate p27 levels in NIH 3T3 cells (Figs. 1C. and 2C. ). p21 mRNA ...
http://cgd.aacrjournals.org/cgi/content/full/10/9/621
*  PTEN/MMAC1 Overexpression Decreases Insulin-like Growth Factor-I-mediated Protection from Apoptosis in Neuroblastoma Cells --...
... inhibits apoptosis in a differentiating neuronal cell line. Mol. Cell. Biol., 18: 2143-2152, 1998.. [Abstract/Free Full Text]. ... Dissociation between resistance to apoptosis and the transformed phenotype in IGF-I receptor signaling. J. Cell. Biochem., 72: ... of the cells from hyperosmotic-induced cell death, the remaining percentage of apoptotic cells equals the percentage of cells ... PTEN Inhibits Neuroblastoma Cell Growth.. PTEN overexpression can induce cell cycle arrest in several cell types (15 , 16 , 45) ...
http://cgd.aacrjournals.org/cgi/content/full/12/7/371
*  The Inhibitory Effects of Transforming Growth Factor {beta}1 on Breast Cancer Cell Proliferation Are Mediated through...
B/Rel blocks transforming growth factor-ß1-induced apoptosis of murine hepatocyte cell lines. Cell Growth Differ., 8: 1049-1059 ... MCF7 and Hs578T (578T) breast tumor cell lines were plated at 1.1 x 104 cells/P100 or 5.6 x 104 cells/P100, respectively, and ... 1. TGF-ß1 treatment decreases proliferation of breast tumor cell lines. MCF7 and Hs578T (578T) breast tumor cell lines were ... Cells were plated the day before treatment: Hs578T cells at densities ranging from 2,600 4,300 cells/cm2 and MCF7 cells at ...
http://cgd.aacrjournals.org/cgi/content/full/10/8/537
*  Nonapoptotic Cell Death Associated with S-Phase Arrest of Prostate Cancer Cells via the Peroxisome Proliferator-activated...
Table 1 Cell cycle analysis of prostate cancer cell lines treated with 15d-PGJ2. Cells were treated with 2.5 and 10 µM 15d-PGJ2 ... Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor ß-1. Proc. Natl. Acad. Sci ... Total cell lysates were prepared from each cell line after treatment with 15d-PGJ2. Adherent and nonadherent cells were ... However, the androgen-dependent cell line, LNCaP, exhibited a lesser effect than the androgen-independent cell lines DU145 and ...
http://cgd.aacrjournals.org/cgi/content/full/11/1/49
*  Cell Cycle-dependent Nuclear Accumulation of the p94fer Tyrosine Kinase Is Regulated by Its NH2 Terminus and Is Affected by...
Treating the three cell lines with aphidicolin significantly enriched the percentage of cells that exhibited preferential ... The DFer gene of Drosophila melanogaster encodes two membrane-associated proteins that can both transform vertebrate cells. ... COS1 and BHK21 were grown in DMEM supplemented with 10% FCS. CHO cells were grown in F12 medium. Cells (4 x 103 2 x 104) cells ... Cells were arrested at the different stages of the cell cycle as follows. Mouse primary fibroblasts and COS1 cells were ...
http://cgd.aacrjournals.org/cgi/content/full/10/2/113
*  Analysis of the Degradation Function of Mdm2 -- Kubbutat et al. 10 (2): 87 -- Cell Growth & Differentiation
To establish cell lines stably expressing Mdm2 mutant proteins, cells were selected after transfection with 0.6 mg/ml G418, and ... and cell cycle arrest activities of Mdm2 have also been reported (16) . Mdm2 shows transforming activities in the absence of ... Cell Culture and Transfections.. U2OS, MCF-7, and Saos-2 cells were maintained in DMEM supplemented with 10% FCS. Cells were ... Cell, 75: 495-505, 1993.. [Medline]. * Haupt Y., Barak Y., Oren M. Cell type-specific inhibition of p53-mediated apoptosis by ...
http://cgd.aacrjournals.org/cgi/content/full/10/2/87
*  Human T-Cell Leukemia Virus Type 1 Tax Protein Inhibits the Expression of the Basic Helix-Loop-Helix Transcription Factor MyoD...
... the MyoD protein level was found to be significantly lower in C2.7-Tax cells than in C2.7-Neo cells when both cell lines were ... a novel pathway for p53 inactivation in human T-cell lymphotropic virus type 1-transformed cells. J. Virol., 72: 6348-6355, ... ßT-cell development and to rapid development of T-cell lymphoma. Mol. Cell. Biol., 17: 4782-4791, 1997.. [Abstract/Free Full ... Yoshida M., Miyoshi I., Hinuma Y. Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia ...
http://cgd.aacrjournals.org/cgi/content/full/12/12/613
*  Differences in Early and Late Responses between Neurotrophin-stimulated trkA- and trkC-transfected SH-SY5Y Neuroblastoma Cells ...
Cell Culture.. SH-SY5Y/wt cells, a subclone of the non-N-myc-amplified human neuroblastoma cell line SK-N-SH (49) kindly ... Von Hippel-Lindau Tumor Suppressor Protein Transforms Human Neuroblastoma Cells into Functional Neuron-like Cells. Cancer Res ... Cells were plated in Eagle s/FCS at a density of 106 cells/10-cm dish, and after 24 h, the cells received fresh medium with or ... Cells were plated overnight in Eagle s/FCS at a density of 5 x 106 cells/10-cm cell culture dish and then serum-starved in ...
http://cgd.aacrjournals.org/cgi/content/full/12/1/39