Pregnancy-Associated alpha-Plasma Protein. Pregnancy-Associated Plasma Protein-A. Protein p34cdc2. CDC2 Protein Kinase. ... G-Protein, Inhibitory Gi. GTP-Binding Protein alpha Subunits, Gi-Go. G-Protein, Stimulatory Gs. GTP-Binding Protein alpha ... Rec A Protein. Rec A Recombinases. Receptor, Platelet-Derived-Growth Factor beta. Receptor, Platelet-Derived Growth Factor beta ... D12 - AMINO ACIDS, PEPTIDES, AND PROTEINS. Mercaptopropionylglycine. Thiopronine. N-substituted Glycine. N-substituted Glycines ...

Pregnancy-Associated alpha-Plasma Protein. Pregnancy-Associated Plasma Protein-A. Protein p34cdc2. CDC2 Protein Kinase. ... G-Protein, Inhibitory Gi. GTP-Binding Protein alpha Subunits, Gi-Go. G-Protein, Stimulatory Gs. GTP-Binding Protein alpha ... Rec A Protein. Rec A Recombinases. Receptor, Platelet-Derived-Growth Factor beta. Receptor, Platelet-Derived Growth Factor beta ... D12 - AMINO ACIDS, PEPTIDES, AND PROTEINS. Mercaptopropionylglycine. Thiopronine. N-substituted Glycine. N-substituted Glycines ...

Pregnancy-Associated alpha-Plasma Protein. Pregnancy-Associated Plasma Protein-A. Protein p34cdc2. CDC2 Protein Kinase. ... G-Protein, Inhibitory Gi. GTP-Binding Protein alpha Subunits, Gi-Go. G-Protein, Stimulatory Gs. GTP-Binding Protein alpha ... Rec A Protein. Rec A Recombinases. Receptor, Platelet-Derived-Growth Factor beta. Receptor, Platelet-Derived Growth Factor beta ... D12 - AMINO ACIDS, PEPTIDES, AND PROTEINS. Mercaptopropionylglycine. Thiopronine. N-substituted Glycine. N-substituted Glycines ...

Pregnancy-Associated alpha-Plasma Protein. Pregnancy-Associated Plasma Protein-A. Protein p34cdc2. CDC2 Protein Kinase. ... G-Protein, Inhibitory Gi. GTP-Binding Protein alpha Subunits, Gi-Go. G-Protein, Stimulatory Gs. GTP-Binding Protein alpha ... Rec A Protein. Rec A Recombinases. Receptor, Platelet-Derived-Growth Factor beta. Receptor, Platelet-Derived Growth Factor beta ... D12 - AMINO ACIDS, PEPTIDES, AND PROTEINS. Mercaptopropionylglycine. Thiopronine. N-substituted Glycine. N-substituted Glycines ...

Pregnancy-Associated alpha-Plasma Protein. Pregnancy-Associated Plasma Protein-A. Protein p34cdc2. CDC2 Protein Kinase. ... G-Protein, Inhibitory Gi. GTP-Binding Protein alpha Subunits, Gi-Go. G-Protein, Stimulatory Gs. GTP-Binding Protein alpha ... Rec A Protein. Rec A Recombinases. Receptor, Platelet-Derived-Growth Factor beta. Receptor, Platelet-Derived Growth Factor beta ... D12 - AMINO ACIDS, PEPTIDES, AND PROTEINS. Mercaptopropionylglycine. Thiopronine. N-substituted Glycine. N-substituted Glycines ...

Pregnancy-Associated alpha-Plasma Protein. Pregnancy-Associated Plasma Protein-A. Protein p34cdc2. CDC2 Protein Kinase. ... G-Protein, Inhibitory Gi. GTP-Binding Protein alpha Subunits, Gi-Go. G-Protein, Stimulatory Gs. GTP-Binding Protein alpha ... Rec A Protein. Rec A Recombinases. Receptor, Platelet-Derived-Growth Factor beta. Receptor, Platelet-Derived Growth Factor beta ... D12 - AMINO ACIDS, PEPTIDES, AND PROTEINS. Mercaptopropionylglycine. Thiopronine. N-substituted Glycine. N-substituted Glycines ...

Pregnancy-Associated alpha-Plasma Protein. Pregnancy-Associated Plasma Protein-A. Protein p34cdc2. CDC2 Protein Kinase. ... G-Protein, Inhibitory Gi. GTP-Binding Protein alpha Subunits, Gi-Go. G-Protein, Stimulatory Gs. GTP-Binding Protein alpha ... Rec A Protein. Rec A Recombinases. Receptor, Platelet-Derived-Growth Factor beta. Receptor, Platelet-Derived Growth Factor beta ... D12 - AMINO ACIDS, PEPTIDES, AND PROTEINS. Mercaptopropionylglycine. Thiopronine. N-substituted Glycine. N-substituted Glycines ...

We show that v-Jun enables cells to express cyclin A and cyclin A-cdk2 kinase activity in the absence of growth factors and ... This is the first report, however, that cyclin E-cdk2, rather than D-cyclin-cdk, is likely to be the critical Rb kinase target ... Cyclin A expression is repressed in quiescent cells by E2F acting in conjunction with its pocket protein partners Rb, p107, and ... Thus, v-Jun overrides the mitogen dependence of S-phase entry by deregulating Rb phosphorylation, E2F-pocket protein ...

... cdc2-kinase subunit) are involved in the progression through the cell cycle. The CKS proteins were first described as ... By using anti-Tcp12CKS1 antiserum, protein kinase (PK) activities were immunoprecipitated. The PK activity level varies ... The functional complementation between the CKS proteins of two evolutionary distant organisms supports the role of Tcp12CKS1 as ... CRKs (cdc2-related kinases), Cyclins and CKSs ( ...

Because many oncogenes encode protein tyrosine kinases (PTKs), much attention had been paid to PTK compared with protein ... Mitosis is initiated following the activation of cdc2-cyclin B kinase complex, so-called M-phase promoting factor or maturation ... Caspase-mediated activation of a 36-kDa myelin basic protein kinase during anticancer drug-induced apoptosis. Cancer Res., 58, ... The receptor-type PTPase, CD45 (a leukocyte common antigen) activates protein tyrosine kinase p56 Ick and p59 fyn , which are ...

page 1005) have isolated a new microtubule-associated protein involved in mitotic spindle formatio ... Biochemical studies have shown that the cyclin-dependent kinase p34cdc2 can phosphorylate the myosin light chain protein LC20 ... Microtubule Interactions with Regulatory Proteins. A New Microtubule-associated Protein in Drosophila. By harnessing the power ... Because p34cdc2 activity declines during anaphase, the in vitro data supported a model in which a decrease in inhibitory ...

Cyclin-dependent kinase 5 (CDK5), a kinase related to the cell cycle kinase cdc2, phosphorylates neurofilaments and regulates ... Alterations in cyclin-dependent protein kinase 5 (CDK5) protein levels, activity and immunocytochemistry in canine motor neuron ... The predicted length of the canine NFH protein is 1135 amino acids, and it shares an 80.3% identity with human NFH and >74.6% ... On immunoblot analysis, CDK5 protein levels were increased in the HCSMA dogs (by approximately 1.5-fold in both the cytosolic ...

Inhibition of phosphatidylinositol 3-kinase or mitogen-activated protein kinase kinase leads to suppression of p34(cdc2) kinase ... protein kinases (mitogen-activated protein kinase (MAPK), АІ, АІІ, В, С, G), epidermal-growth factors (EGF), EGF-like factors, ... PI3-kinase and mitogenactivated protein kinase in cumulus cells mediate EGFinduced meiotic resumption of porcine oocyte . ... Su Y.Q., Wigglesworth K., Pendola F.L., OBrien M.J., Eppig J.J. Mitogen-activated protein kinase activity in cumulus cells is ...

Reversible phosphorylation of proteins by kinases and phosphatases plays a key regulatory role in several eukaryotic cellular ... A set of cdc2-related genes (cdc2Ms A, B, D and F) was expressed in G2 and M cells. Phosphorylation assays also revealed that ... Reversible phosphorylation of proteins by kinases and phosphatases plays a key regulatory role in several eukaryotic cellular ... Reversible phosphorylation of proteins by kinases and phosphatases plays a key regulatory role in several eukaryotic cellular ...

CDKN1C Protein; Cyclin-Dependent Kinase Inhibitor 1C; Cyclin-Dependent Kinase Inhibitor p57; KIP2 Protein; p57-KIP2 Protein = ... and also inhibits mitotic Cyclin B-CDC2. The N-terminal CDK inhibitory domain is similar to p21(CIP1). (from SWISS-PROT P49918 ... 424-aa Tumor Suppressing Subtransferable Candidate 5 Protein (Organic Cation Transporter-Like 2 Protein) is a polyspecific ... NCI04) ( NCI )] (UMLS (NCI) C0053065) =Amino Acid, Peptide, or Protein; Antibiotic 153. beginning [Condition is tested every ...

Similar rho-binding domains also occur in a number of other protein kinases and in the rho-binding proteins rhophilin and ... which is closely related to Cdc42-interacting protein 4 (CIP4), effectors of the Rho family small G protein Cdc2 [ (PUBMED: ... Rho effector or protein kinase C-related kinase homology region 1 homologues. ... HR1 was first described as a three times repeated homology region of the N-terminal non-catalytic part of protein kinase PRK1( ...

The phosphatidyl inositol 3-kinase (PI3K)/Akt pathway was involved in this ubiquitin-proteasome-mediated degradation of PDCD4. ... decreased PDCD4 protein but not mRNA level. Immunoprecipitation revealed that pulsatile shear stress induced the coupling of ... Goke R, Barth P, Schmidt A, Samans B, Lankat-Buttgereit B (2004) Programmed cell death protein 4 suppresses CDK1/cdc2 via ... 2006) AMP-activated protein kinase is involved in endothelial NO synthase activation in response to shear stress. Arterioscler ...

At molecular level, down-regulation of HSP70-2 resulted in reduced expression of cyclins, cyclin dependent kinases, anti- ... Further, we studied the effect of HSP70-2 protein ablation on signaling cascades involved in apoptosis, cell cycle and ... HSP70-2 is required for CDC2 kinase activity in meiosis I of mouse spermatocytes. Development. 1997;124:3007-14. ... A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer. J Exp Clin Cancer Res. 2015;34:142. ...

A Dual-Specificity Phosphatase Cdc25B Is an Unstable Protein and Triggers p34cdc2/Cyclin B Activation in Hamster BHK21 Cells ... Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential ... Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential ... Since p34cdc2/cyclin B physically associated with MAP4, we examined the ability of the kinase complex to phosphorylate MAP4. ...

Abl-enhanced maturation was normal as judged by accumulation of Mos as well as activation of MAP kinase and Cdc2/CyclinB (MPF ... Deregulated activity of the Abl protein tyrosine kinase is oncogenic in humans and in animals. The normal cellular form of the ... Abl-enhanced maturation was normal as judged by accumulation of Mos as well as activation of MAP kinase and Cdc2/CyclinB (MPF ... Deregulated activity of the Abl protein tyrosine kinase is oncogenic in humans and in animals. The normal cellular form of the ...

... protein was found downregulated across the grades. AKAP12 knockdown in benign meningioma cells SF4433 increases proliferation, ... In the discovery set of fresh-frozen tissue specimens (14), the A-kinase anchor protein 12 (AKAP12) ... b) Kinases on the phylogenetic tree and bar graphs showing percent of kinases (X axis) classified in each major kinase group (Y ... CDC2_154_169, and CA2D1_494_506 peptides, suggesting activation of the MTOR signaling as well as dysregulation in cascades ...

Hemerly A, JdA E, Bergounioux C, Van Montagu M, Engler G, Inze D, Ferreira P. Dominant negative mutants of the Cdc2 kinase ... Knockdown of OsBZR1 expression causes reduced seed size and weight by triggering expression of a MYB domain protein, carbon ... controls cell cycle at mitosis by stimulating the tyrosine dephosphorylation and activation of p34cdc2-like H1 histone kinase [ ... Guo W-J, T-HD H. An abscisic acid-induced protein, HVA22, inhibits gibberellin-mediated programmed cell death in cereal ...

Mitotic reorganization of the intermediate filament protein nestin involves phosphorylation by cdc2 kinase. J Biol Chem. 2001; ... The localization of the protein was specified by co-immunoreactivity with glial fibrillary protein (GFAP), glutamine synthetase ... Xue LP, Lu J, Cao Q, Hu S, Ding P, Ling E-A. Müller glial cells express nestin coupled with glial fibrillary acidic protein in ... The glial localization of nestin was studied by the coexpression of this protein with glial markers such as GFAP and GS. GFAP ...

Roscovitine targets, protein kinases and pyridoxal kinase: S. Bach, et al.; J. Biol. Chem. 280, 31208 (2005), Abstract; ... Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 ... The specificities of protein kinase inhibitors: an update: J. Bain, et al.; Biochem. J. 371, 199 (2003), Abstract; ... Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related ...

The N-terminal region of the LATS1 protein binds CDC2 to form a complex showing decreased H1 histone kinase activity, ... Using a MalE-EnvZ kinase, but not the cognate partner kinase of MtrB, Rajagopalan et al suggested that the phosphorylation of ... stress gene family protein (MSMEG_3308), and the isoniazid inducible protein IniA (MSMEG_0695). Inhibition of the mtrA gene, ... The diversity of these proteins is reflected in their mode of action and their species-specificity. Some of them form pores in ...

Cyclin-Dependent Kinases. CDC2 Protein Kinase. Cell Cycle. Cell Cycle Proteins. Saccharomyces cerevisiae Proteins. Cyclin B. ... Cyclin-Dependent Kinases. CDC2 Protein. Biochemistry. Cell Biology. Molecular Biology Show allShow less ... Cell Cycle Proteins. Saccharomyces cerevisiae Proteins. Cyclin B. Cyclin G1. Cyclins. ... Multiple rounds of centrosome reproduction were blocked by selective inactivation of cyclin-dependent kinase 2-cyclin E (Cdk2-E ...

Carrier Proteins. * CDC2 Protein Kinase. * Cell Line, Tumor. * Cell Proliferation. * Colorectal Neoplasms ...

CDC7 (Cell Division Cycle 7-related Protein Kinase). * CHK (Checkpoint Kinase). * CLK (CDC2-like-Kinase) ... Cell Division Cycle 7-related Protein Kinase) CDC7 (Cell Division Cycle 7-related Protein Kinase) ... TOPK (T-lymphokine-activated killer cell-originated protein kinase). * TRK (Tropomyosin Receptor Kinase) (Tyrosine Receptor ... BTK (Brutons Tyrosine Kinase). * BUB1 (Budding Uninhibited by Benzimidazoles 1)(Mitotic checkpoint serine/threonine-protein ...