THU0187 Memory B Cells Produce More TNF Than Other B Cell Subtypes and Their Percentage at Baseline Could Help to Predict...
Indeed, memory B cells were more often positive for TNF than non-memory B cells (23[7-47] vs 19 [1-31]% of B cells; p,0.05). ... Conclusions No major change in terms of lymphocytes was seen after 3 months of TNFi. Memory B cells produce more TNF than other ... Extra-cellular staining with antibodies directed against CD5, CD19, CD24, CD27, CD38, IgD, IgM, CD3, CD4, CD8, CD25, CD127, ... Effects of TNFi on lymphocytes are not so clear and studies are controversial. Moreover, many biologics are now available to ...http://ard.bmj.com/content/72/Suppl_3/A226.3
Immunoelectron-microscopic study of CD4- and CD8- positive lymphocytes from healthy donors seropositive for human T...
In order to determine the fine structural differences and labeling by immunoferritin particles of CD4-positive (CD4+) and CD8 ... Immunoelectron-microscopic study of CD4- and CD8- positive lymphocytes from healthy donors seropositive for human T- ... In order to determine the fine structural differences and labeling by immunoferritin particles of CD4-positive (CD4+) and CD8 ... Sera of eight donors were all positive on the particle agglutination (PA) test, but only of the four of the eight were positive ...http://www.alliedacademies.org/abstract/immunoelectronmicroscopic-study-of-cd4-and-cd8-positive-lymphocytes-from-healthy-donors-seropositive-for-human-tlymphotropic-virus-723.html
P2.146 CD4 Lymphocytes Count At First Presentation of HIV Positive Patients Accessing Antiretroviral Therapy At a District...
P2.146 CD4 Lymphocytes Count At First Presentation of HIV Positive Patients Accessing Antiretroviral Therapy At a District ... P2.146 CD4 Lymphocytes Count At First Presentation of HIV Positive Patients Accessing Antiretroviral Therapy At a District ... The study determined the CD4 lymphocytes count levels of HIV positive patient at first presentation at STI/HIV Clinic at ... of all HIV positive patients presented with CD4 count of less than 250 cells/mm3. 20.7% (183/883) reported with CD4 count less ...http://sti.bmj.com/content/89/Suppl_1/A132.3
T-lymphocyte Infiltration in Visceral Adipose Tissue | Arteriosclerosis, Thrombosis, and Vascular Biology
Immunohistochemical staining for CD4-positive lymphocytes. (B, high power view). D and E, Lack of CD8-positive lymphocytes in ... These lymphocytes are mainly CD4-positive lymphocytes which express proinflammatory TH1-cytokines like IFNγ and orchestrate the ... Most macrophages were HLA-DR-positive, reflecting activation through IFNγ, a cytokine released from CD4-positive lymphocytes. ... Human Adipose Tissue Contains CD4-Positive Lymphocytes. To further characterize the lymphocyte population in human adipose ...http://atvb.ahajournals.org/content/28/7/1304.long
TNK cells (NKG2D+ CD8+ or CD4+ T ... preview & related info | Mendeley
CD4-Positive T-Lymphocytes. *CD4-Positive T-Lymphocytes: immunology. *CD8-Positive T-Lymphocytes ... Among these, the NKG2D molecule was identified as expressed by T lymphocytes, including most CD8+ cells and a minority of CD4+ ... Moreover, NKG2D and TCR triggering was also observed by peripheral blood derived T lymphocyte- or T cell clone-mediated tumor ... TNK cells (NKG2D+ CD8+ or CD4+ T lymphocytes) in the control of human tumors.. *Maccalli C ...https://www.mendeley.com/research-papers/tnk-cells-nkg2d-cd8-cd4-t-lymphocytes-control-human-tumors-1/
Therapeutic Approaches to HAART-Induced Lipodystrophy - Full Text View - ClinicalTrials.gov
Blood CD4 positive lymphocyte count , 200/mm3. *Known liver disease due to causes other than nonalcoholic steatohepatitis with ...https://clinicaltrials.gov/show/NCT00461552?order=497
HIV Resistance and Treatment Strategies - Full Text View - ClinicalTrials.gov
CD4-Positive T-Lymphocytes. Treatment Naive. Latent HIV Infections. Additional relevant MeSH terms: ... Memory CD4 cells may provide a reservoir of latent HIV that cannot be completely eliminated using currently available anti-HIV ... CD4-cell subsets, cellular anti-HIV factors, and cellular drug transporters will be observed to determine which resting memory ... Characterization of memory CD4 cell subsets isolated from chemotherapeutically suppressed participants [ Time Frame: At the end ...https://clinicaltrials.gov/show/NCT00581802?order=293
A Study of Immune System Activity in Healthy Adults - Full Text View - ClinicalTrials.gov
CD4-Positive T-Lymphocytes. HIV Seronegativity. Antigens, CD. Additional relevant MeSH terms: ... Enhanced lymphocyte apoptosis may play an important role in the pathogenesis of HIV disease. This study will use healthy ... DTH hypersensitivity to skin test antigens, lymphocyte proliferation to mitogens, soluble antigens, recall antigens, and ... Another possible mechanism of diminished cellular immunity associated with age includes accelerated lymphocyte apoptosis. ...https://clinicaltrials.gov/show/NCT00014053?order=304
Observing Patients With Early HIV Infection - Full Text View - ClinicalTrials.gov
CD4 Lymphocyte Count. CD4-Positive T-Lymphocytes. Phenotype. Viral Load. Acute Infection. ... The first is that CD4 target cell numbers are depleted, so the reduction in permissive target cells limits viral replication. A ... second is that the host develops an HIV-specific cytotoxic T lymphocyte (CTL) immune response that limits viral replication ...https://clinicaltrials.gov/show/NCT00005020?order=293
Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive Adults - Full Text View -...
CD4-Positive T-Lymphocytes. Immunologic Memory. Pentafuside. Anti-HIV Agents. Drug Therapy, Combination. Saquinavir. Ritonavir ... Resting memory CD4 cells have been proposed as providing a cellular reservoir. Most patients who initiate ART during chronic ... The purpose of this study is to test the ability of a T-20-enhanced treatment regimen to decrease the number of resting CD4 ... HIV replication in resting CD4 cells is so minimal that anti-HIV drugs often fail to destroy the virus in these cells. ...https://clinicaltrials.gov/show/NCT00051831?order=31
A Multicenter Study To Determine Foscarnet Dose Response in HIV Infected Patients With PGL and/or Constitutional Disease - Full...
CD4-Positive T-Lymphocytes. Additional relevant MeSH terms: HIV Infections. Lentivirus Infections. Retroviridae Infections. RNA ... or other HIV associated conditions and a CD4+ lymphocyte count , 500 cells/mm3. To obtain preliminary efficacy data. Although ...https://clinicaltrials.gov/show/NCT00000729
Administration of Growth Hormone to Increase CD4+ Count in Patients Taking Anti-HIV Drugs - Full Text View - ClinicalTrials.gov
CD4 Lymphocyte Count. Antiretroviral Therapy, Highly Active. Growth Hormone. Cell Division. CD4-Positive T-Lymphocytes. ... Thymic size and lymphocyte restoration in patients with human immunodeficiency virus infection after 48 weeks of zidovudine, ... Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone. AIDS. 2002 May 24 ... Improving Immune Reconstitution With Growth Hormone in HIV-infected Subjects With Incomplete CD4+ Lymphocyte Restoration on ...https://clinicaltrials.gov/ct2/show/study/NCT00050921?view=results
Effectiveness of Early or Delayed Addition of Hydroxyurea to a Three-Drug Anti-HIV Drug Combination Including Didanosine, in...
CD4-Positive T-Lymphocytes. Hydroxyurea. RNA, Viral. Genotype. Reverse Transcriptase Inhibitors. Anti-HIV Agents. Viral Load. ... Have a CD4 count under 300 cells/mm3 within 45 days prior to study entry. ...https://clinicaltrials.gov/ct2/show/NCT00008866
Effectiveness of Adding Interleukin-2 to Anti-HIV Drugs in Patients Recently Infected With HIV - Full Text View -...
CD4-Positive T-Lymphocytes. CD8-Positive T-Lymphocytes. Biological Markers. Lamivudine. Reverse Transcriptase Inhibitors. Anti- ... cytotoxic T cell lymphocyte function and CD4 T helper function correlates with the patterns of cellular immune antiviral ... a cohort of HIV negative individuals that tested with the Options Project to use as a comparison group with the HIV positive ...https://clinicaltrials.gov/show/NCT00006441?order=38
A Phase I Safety and Immunogenicity Trial of HIV-1 gp120 C4-V3 Hybrid Polyvalent Peptide Immunogen Mixed in Mineral Oil...
CD4-Positive T-Lymphocytes. CD8-Positive T-Lymphocytes. HIV Seronegativity. Neutralization Tests. Mineral Oil. Oleic Acids. ... Active syphilis (if the serology is documented to be a false positive or due to a remote [more than 6 months] treated infection ... Active tuberculosis (volunteers with a positive purified protein derivative and a normal chest x-ray showing no evidence of TB ... CD8+ and CD4+ cytotoxic T lymphocyte (CTL) activity specific for HIV-1 gp120 or V3 peptides corresponding to the vaccine ...https://clinicaltrials.gov/show/NCT00000886?order=110
A Study of Tucaresol in HIV-Infected Patients Who Are Taking Other Anti-HIV Drugs - Full Text View - ClinicalTrials.gov
CD4-Positive T-Lymphocytes. Antigens. Anti-HIV Agents. Viral Load. tucaresol. Additional relevant MeSH terms: ...https://clinicaltrials.gov/ct2/show/study/NCT00006209?view=record
An Open Trial of Zidovudine (AZT) Treatment of the AIDS Dementia Complex in Patients With AIDS or Low CD4+ Lymphocyte Counts -...
CD4-Positive T-Lymphocytes. Additional relevant MeSH terms: HIV Infections. Dementia. AIDS Dementia Complex. Lentivirus ... An Open Trial of Zidovudine (AZT) Treatment of the AIDS Dementia Complex in Patients With AIDS or Low CD4+ Lymphocyte Counts. ... An Open Trial of Zidovudine (AZT) Treatment of the AIDS Dementia Complex in Patients With AIDS or Low CD4+ Lymphocyte Counts. ...https://clinicaltrials.gov/show/NCT00000709?order=351
CXCR5 | Cancer Genetics Web
T-Lymphocytes, Helper-Inducer. *Receptors, Chemokine. *CD4-Positive T-Lymphocytes. *TNF. *Cell Movement ... Intratumoral CD4(+)PD-1(high) T cells have a TFH cell phenotype, express CXCR5, secrete IL-21 and are BCL-6 positive with no ... Functionally, CD4(+)PD-1(high) T cells actively supported B-cell growth, while CD4(+)PD-1(low) T cells displayed a reduced ... The goal of our study was to functionally characterize intratumoral CD4(pos) T cells. We showed that CXCR5(hi)ICOS(hi)CD4(pos) ...http://www.cancerindex.org/geneweb/CXCR5.htm
HLA class II molecules influence susceptibility versus protection in inflammatory diseases by determining the cytokine profile.
CD4-Positive T-Lymphocytes / immunology. Cytokines / metabolism*. Disease Susceptibility* / immunology. HLA-D Antigens / ... Previous Document: Lamprey Variable Lymphocyte Receptors Mediate Complement-Dependent Cytotoxicity.. Next Document: A general ...http://www.biomedsearch.com/nih/HLA-Class-II-Molecules-Influence/23293357.html
Physiological induction of regulatory Qa-1-restricted CD8+ T cells triggered by endogenous CD4+ T cell responses.
CD4-Positive T-Lymphocytes / immunology*. CD8-Positive T-Lymphocytes / immunology*. Cells, Cultured. Encephalomyelitis, ... Represented is the percentage of tetramer-positive cells among total CD4+ T cells in the CNS. C. Absolute numbers of CD4+ T ... Monoclonal antibodies specific for CD4 (clone RM4-5), CD8 (clone 53-6.7) and CD3 (clone 145-2C11) at a concentration of 2 µg/ml ... Figure 4 Regulatory CD8+ T cells prevent lymphocyte infiltration and CNS inflammation. Naïve mice were adoptively transferred ...http://www.biomedsearch.com/nih/Physiological-Induction-Regulatory-Qa-1/21738737.html
Two-Stage Tuberculin (PPD) Skin Testing in Individuals With Human Immunodeficiency Virus (HIV) Infection - Full Text View -...
... to determine the relationship between the booster phenomenon and CD4-positive lymphocyte cell counts; to detect any ... Patients with a positive skin test (defined as an induration, or small hard knot, of 5 mm or greater forming beneath the skin) ... History of documented positive PPD skin test.. *History of tuberculosis or who are presently receiving chemoprophylaxis or ... attainment of a positive response to a second tuberculin purified protein derivative skin test when the first skin test was ...https://www.clinicaltrials.gov/ct2/show/NCT00000955
Dietary antioxidants and behavioral enrichment enhance neutrophil phagocytosis in geriatric Beagles.
CD4-Positive T-Lymphocytes / cytology, immunology. CD8-Positive T-Lymphocytes / cytology, immunology. Carnitine / pharmacology ... There were no significant differences between the groups of dogs for percentages of CD4 and CD8 T-lymphocyte subpopulations ... Simultaneous stimulation of cells with Con A and suppression with Dex resulted in decreased lymphocyte proliferation in dogs ... before or after lymphocyte stimulation with Con A. These results support our hypothesis that both dietary antioxidants and ...http://www.biomedsearch.com/nih/Dietary-antioxidants-behavioral-enrichment-enhance/16806493.html
Heat-shock protein 60-reactive CD4+CD28null T cells in patients with acute coronary syndromes.
CD4+CD28null T cells are present in increased numbers in the peripheral blood of patients with acute coronary syndrome (ACS) ... CD4 Lymphocyte Count. CD4-Positive T-Lymphocytes / immunology*, metabolism. Cell Separation. Chaperonin 60 / blood, immunology* ... CD4+CD28null cells from 12 of 21 patients with ACS reacted with hHSP60. No response was detected to HCMV, C pneumoniae, or ox- ... BACKGROUND: CD4+CD28null T cells are present in increased numbers in the peripheral blood of patients with acute coronary ...http://www.biomedsearch.com/nih/Heat-shock-protein-60-reactive/14993140.html
Effect of Rosiglitazone Treatment on Plaque Inflammation and Collagen Content in Nondiabetic Patients | Arteriosclerosis,...
Representative sections of shoulder regions stained for CD4-positive lymphocytes and CD68-positive macrophages are shown from ... CD4-positive lymphocytes are major effectors of the inflammatory response in the vessel wall through their capacity to release ... This may be attributable to a reduction of IFN-γ release from CD4-positive lymphocytes by TZDs because IFN-γ, on the one hand, ... Given the nodal role of CD4-positive lymphocytes in vessel wall inflammation, we next examined the expression of HLA-DR, a ...http://atvb.ahajournals.org/content/26/4/845
Nc/Nga mice model - Wikipedia
This infiltrate consists mainly of CD4 positive T lymphocytes with less CD8 positive lymphocytes and macrophages. Infiltration ... All these genes or their products more precisely are involved in T lymphocytes development. Derm1 region is conserved on human ...https://en.wikipedia.org/wiki/Nc/Nga_mice_model