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*  CYR61 - Wikipedia
... associated signaling protein of the CCN family (CCN intercellular signaling protein). CYR61 is capable of regulating a broad ... Other highly conserved homologs were later identified to comprise the CCN protein family (CCN intercellular signaling protein ... CCN proteins function as matricellular proteins, which are extracellular matrix proteins that play regulatory roles, ... fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines". J. Cell Commun. Signal ...
https://en.wikipedia.org/wiki/CYR61
*  CCN protein - Wikipedia
CCN proteins are a family of extracellular matrix (ECM)-associated proteins involved in intercellular signaling. Due to their ... CCN proteins likely constitute a hub for the coordination of cell signaling and communication. The CCN protein family includes ... 4(5), 477-494, DOI: 10.1515/bmc-2013-0018, CCN Intercellular Signaling Proteins at the US National Library of Medicine Medical ... WNT1 inducible signaling pathway protein-2) CCN6: WISP3 (WNT1 inducible signaling pathway protein-3) Jun JI, Lau LF (December ...
https://en.wikipedia.org/wiki/CCN_protein
*  WNT1-inducible-signaling pathway protein 3 - Wikipedia
CCN intercellular signaling protein) of secreted, extracellular matrix (ECM)-associated signaling matricellular proteins. The ... comprise the six-member CCN family in vertebrates. CCN proteins characteristically contain an N-terminal secretory signal ... WNT1-inducible-signaling pathway protein 3 (WISP3, also named CCN6) is a matricellular protein that in humans is encoded by the ... The CCN family of proteins regulates diverse cellular functions, including cell adhesion, migration, proliferation, survival, ...
https://en.wikipedia.org/wiki/WNT1-inducible-signaling_pathway_protein_3
*  NOV (gene) - Wikipedia
... associated signaling proteins (see also CCN intercellular signaling protein). The CCN acronym is derived from the first three ... These proteins, together with WISP1 (CCN4), WISP2 (CCN5), and WISP3 (CCN6) comprise the six-member CCN family in vertebrates ... The human NOV protein contains 357 amino acids with an N-terminal secretory signal peptide followed by four structurally ... Chen CC, Lau LF (Apr 2009). "Functions and mechanisms of action of CCN matricellular proteins". The International Journal of ...
https://en.wikipedia.org/wiki/NOV_(gene)
*  Extracellular Matrix Proteins < Scleroproteins << Proteins (Protein Science) <<< Compounds of Life @...
ECM Proteins) are macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur ... Cartilage Oligomeric Matrix Protein *CCN Intercellular Signaling Proteins *Connective Tissue Growth Factor *Cysteine-Rich ... ADAMTS Proteins *ADAMTS1 Protein *ADAMTS4 Protein *ADAMTS5 Protein *ADAMTS7 Protein *ADAMTS9 Protein *ADAMTS13 Protein * ... Extracellular Matrix Proteins Extracellular Matrix Proteins (ECM Proteins) Extracellular Matrix (ECM). In our body, the ...
http://wellnessadvocate.com/?dgl=70212
*  Matricellular protein - Wikipedia
Examples of matricellular proteins include the CCN family of proteins (also known as CCN intercellular signaling protein), ... Many of these proteins have important functions in wound healing and tissue repair. CCN protein Bornstein P (August 1995). " ... Jun JI, Lau LF (December 2011). "Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets". Nat Rev ... A matricellular protein is a dynamically expressed non-structural protein that is present in the extracellular matrix (ECM). ...
https://en.wikipedia.org/wiki/Matricellular_protein
*  WNT1-inducible-signaling pathway protein 1 - Wikipedia
... associated signaling proteins (CCN intercellular signaling protein). The CCN family of proteins shares a common molecular ... WNT1-inducible-signaling pathway protein 1 (WISP-1), also known as CCN4, is a matricellular protein that in humans is encoded ... WISP1 WNT1 inducible signaling pathway protein 1". Chen CC, Lau LF (Apr 2009). "Functions and mechanisms of action of CCN ... Leask A, Abraham DJ (Dec 2006). "All in the CCN family: essential matricellular signaling modulators emerge from the bunker". ...
https://en.wikipedia.org/wiki/WNT1-inducible-signaling_pathway_protein_1
*  CCN - Wikipedia
... the first three proteins identified that belong to the "CCN" protein family - also see CCN intercellular signaling protein ... CCN may refer to: Cement chemist notation, developed to simplify the formulas used by cement chemists Cereal cyst nematode, a ...
https://en.wikipedia.org/wiki/CCN
*  CTGF - Wikipedia
... see also CCN intercellular signaling protein). CTGF has important roles in many biological processes, including cell adhesion, ... is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins ( ... Members of the CCN protein family, including CTGF, are structurally characterized by having four conserved, cysteine-rich ... Chen CC, Lau LF (April 2009). "Functions and mechanisms of action of CCN matricellular proteins". Int. J. Biochem. Cell Biol. ...
https://en.wikipedia.org/wiki/CTGF
*  配體 (生物化學) - 维基百科,自由的百科全
CCN intercellular signaling protein *Cysteine-rich protein 61. *Connective tissue growth factor ... Protein-binding assays in biological liquids using microscale thermophoresis. Nature Communications. 2010, 1 (7): 100. Bibcode: ... BindingDB, a public database of measured protein-ligand binding affinities.. *BioLiP, a comprehensive database for ligand- ... Teif VB, Rippe K. Statistical-mechanical lattice models for protein-DNA binding in chromatin.. Journal of Physics: Condensed ...
https://zh.wikipedia.org/wiki/%E9%85%8D%E9%AB%94_
*  Parathyroid hormone-related protein - Wikipedia
Agouti signaling protein. *Agouti-related protein. *Angiogenic protein. *CCN intercellular signaling protein *Cysteine-rich ... G-protein coupled receptor signaling pathway. • bone mineralization. • negative regulation of chondrocyte development. ... Parathyroid hormone-related protein (or PTHrP) is a protein member of the parathyroid hormone family. It is occasionally ... adenylate cyclase-activating G-protein coupled receptor signaling pathway. • cAMP metabolic process. • positive regulation of ...
https://en.wikipedia.org/wiki/Parathyroid_hormone-related_protein
*  Ephrin A4 - Wikipedia
Agouti signaling protein. *Agouti-related protein. *Angiogenic protein. *CCN intercellular signaling protein *Cysteine-rich ... cell-cell signaling. • ephrin receptor signaling pathway. • axon guidance. • osteoclast differentiation. • bone remodeling. ... Three transcript variants that encode distinct proteins have been identified.[6] References[edit]. *^ a b c GRCh38: Ensembl ... Binding proteins: IGFBP (1, 2, 3, 4, 5, 6, 7). *Cleavage products/derivatives with unknown target: Glypromate (GPE, (1-3)IGF-1) ...
https://en.wikipedia.org/wiki/EFNA4
*  Ligand (biochemistry) - Wikipedia
Agouti signaling protein. *Agouti-related protein. *Angiogenic protein. *CCN intercellular signaling protein *Cysteine-rich ... In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein. ... In DNA-ligand binding studies, the ligand can be a small molecule, ion,[1] or protein[2] which binds to the DNA double helix. ... Teif VB, Rippe K (October 2010). "Statistical-mechanical lattice models for protein-DNA binding in chromatin". Journal of ...
https://en.wikipedia.org/wiki/Ligand_binding
*  Ephrin A5 - Wikipedia
Agouti signaling protein. *Agouti-related protein. *Angiogenic protein. *CCN intercellular signaling protein *Cysteine-rich ... Reverse signaling in growth cone survival[edit]. "Reverse" signaling is one unique property of ephrin ligands that allows for ... Binding proteins: IGFBP (1, 2, 3, 4, 5, 6, 7). *Cleavage products/derivatives with unknown target: Glypromate (GPE, (1-3)IGF-1) ... protein binding. Cellular component. • membrane. • plasma membrane. • anchored component of external side of plasma membrane. • ...
https://en.wikipedia.org/wiki/EFNA5
*  Cicatrix | ISHAR Online
CCN Intercellular Signaling Proteins. Cell-Matrix Junctions. Cicatrix. Extracellular Matrix. Fibroblasts. Humans ...
http://isharonline.org/tags/cicatrix
*  Transforming growth factor beta superfamily - Wikipedia
Agouti signaling protein. *Agouti-related protein. *Angiogenic protein. *CCN intercellular signaling protein *Cysteine-rich ... Receptor/signaling modulators. Signaling peptide/protein receptor modulators. Growth factor receptor modulators. Cytokine ... These proteins interact with a conserved family of cell surface serine/threonine-specific protein kinase receptors, and ... Human genes encoding proteins that contain this domain include:. AMH; ARTN; BMP10; BMP15; BMP2; BMP3; BMP4; BMP5; BMP6; BMP7; ...
https://en.wikipedia.org/wiki/Tgf_beta_superfamily
*  Protocols and Video Articles Authored by Wen-Chi Chen (Translated to Danish)
CCN6 is a cysteine-rich protein that belongs to the CCN (Cyr61, CTGF, and Nov) family of matricellular proteins. However, the ... Dec, 2012 , Pubmed ID: 23237992 Suppressor of cytokine signaling 1 (SOCS1) and suppressor of cytokine signaling 3 (SOCS3) have ... In this study, we found that CCN6 increased the migration and the expression of intercellular adhesion molecule-1 (ICAM-1) in ... Feb, 2009 , Pubmed ID: 19126648 Cysteine-rich 61 (Cyr61), from the CCN gene family, is a secreted and matrix-associated protein ...
https://www.jove.com/author/Wen-Chi_Chen?language=Danish
*  Endothelin
Agouti signaling protein. *Agouti-related protein. *Angiogenic protein. *CCN intercellular signaling protein *Cysteine-rich ... The ARE-binding protein AUF1 has been linked to the ubiquitin-proteasome pathway. AUF1 mRNA destabilizing activity has been ... Several RNA-binding proteins with affinities for AREs have been characterized including AUF1 (hnRNPD), the ELAV family (HuR, ... Recent studies have revealed a functional link between AUF1, heat shock proteins and the ubiquitin-proteasome network. ...
https://readtiger.com/wkp/en/Endothelin
*  Insulin-like growth factor
Agouti signaling protein. * Agouti-related protein. * Angiogenic protein. * CCN intercellular signaling protein * Cysteine-rich ... IGF-Binding Proteins IGF-1 and IGF-2 are regulated by a family of proteins known as the IGF-Binding Proteins. These proteins ... Binding proteins: IGFBP (1, 2, 3, 4, 5, 6, 7). * Cleavage products/derivatives with unknown target: Glypromate (GPE, (1-3)IGF-1 ... The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system ...
https://ipfs.io/ipfs/QmXoypizjW3WknFiJnKLwHCnL72vedxjQkDDP1mXWo6uco/wiki/Insulin-like_growth_factor.html
*  SPARC modulates the spinal cord neuroimmune response in experimental autoimmune encephalomyelitis - UBC Library Open Collections
... a TJ associated protein, anchors TJ proteins to the cytoskeleton and regulates signaling pathways that promote BBB formation ( ... CCN) family, the thrombospondin family, and the tenascins (Bornstein, 2000, Clark and Sage, 2008) 1.2 Secreted Protein Acidic ... as the extracellular component of connective tissue that provides structural support and regulates intercellular signaling. The ... 1.1.1 Matricellular proteins Matricellular proteins are ECM associated proteins that do not serve structural roles in the ECM, ...
https://open.library.ubc.ca/cIRcle/collections/ubctheses/24/items/1.0072158
*  The emerging role of WISP proteins in tumorigenesis and cancer therapy | Journal of Translational Medicine | Full Text
... which belong to members of the CCN growth factor family, play a pivotal role in tumorigenesis and progression of a broad ... Because the understanding of a direct function of WISP proteins in cancer development and progression has begun to emerge, in ... Furthermore, we discuss that targeting WISP proteins could be a promising strategy for the treatment of human cancers. Hence, ... Moreover, we highlight the current understanding of how the WISP protein is involved in tumorigenesis and cancer progression. ...
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-019-1769-7
*  Connexin and pannexin channels in cancer | Springer for Research & Development
Several published studies suggest that connexin proteins influence cell cycle and signaling independently of their roles in ... Intercellular communication between cells is realized through gap junction channels formed by connexins (Cx). In the last ... A direct link of Cx43 and CCN in anti-proliferative function. [67] ... of human melanoma tumours show high levels of Panx1 protein (Human Protein Atlas [161]).. Table 2 Summary of the current ...
https://rd.springer.com/article/10.1186/s12860-016-0094-8
*  Transgenic Expression of A Venous Malformation Related Mutation, TIE2-R849W, Significantly Induces Multiple Malformations of...
The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signaling. The Journal of ... Context-dependent proangiogenic function of bone morphogenetic protein signaling is mediated by disabled homolog 2. ... wnt-related ligands and intercellular signaling molecules increase above normal expression levels under the influence of TIE2- ... Angiopoietin-1/Tie2 signal augments basal Notch signal controlling vascular quiescence by inducing delta-like 4 expression ...
http://www.medsci.org/v15p0385.htm
*  Plus it
2007) A translocation signal for delivery of oomycete effector proteins into host plant cells. Nature 450: 115-118. ... 2010) Sugar transporters for intercellular exchange and nutrition of pathogens. Nature 468: 527-532. ... van Schie CCN, *Takken FLW. (2014) Susceptibility genes 101: how to be a good host. Annu Rev Phytopathol 52: 551-581. ... nuclear export signal. NLS. nuclear localization signal. Y2H. yeast two-hybrid. cDNA. complementary DNA. PM. plasma membrane. ...
http://www.plantphysiol.org/content/171/1/645
*  Faculty Collaboration Database - Mesh term CCN Intercellular Signaling Proteins
Mesh term CCN Intercellular Signaling Proteins. Browse to parent terms:. Extracellular Matrix Proteins. Intercellular Signaling ... The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and ... Cysteine-Rich Protein 61. Nephroblastoma Overexpressed Protein. Search for this term in our Faculty Database. View this term at ... A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to ...
https://fcd.mcw.edu/?module=search&func=showTerm&id=68055511