The cathepsin B inhibitor z-FA-CMK induces cell death in leukemic T cells via oxidative stress. January 2018 · Naunyn- ... The cathepsin B inhibitor benzyloxycarbonyl-phenylalanine-alanine-chloromethyl ketone (z-FA-CMK) was recently found to induce ...

Cysteine cathepsins are fundamental regulators of the innate and adaptive arms of the immune system. Cysteine cathepsins are ... Redundant cathepsins are involved in generating peptides for MHC II presentation (25).by infected macrophages (34).Cathepsin B ... It is facilitated by another cysteine peptidase, cathepsin X (40). Cathepsin X is not inhibited by cystatin F, however, since ... as a cathepsin L inhibitor, indirectly controls cathepsin X dependent adhesion, and the maturation of dendritic cells (86). ...

Cited in 4 publications. View Mouse Monoclonal anti-UGCG Antibody (1E5) (H00007357-M03). Validated Applications: WB, ELISA. Validated Species: Human.

Expression of matrix metalloproteinases-1, -2, and -9; tissue inhibitors of matrix metalloproteinases-1 and -2; cathepsin B; ...

CATHEPSIN E. CATEPSINA E. CÉLULAS CALICIFORMES. GOBLET CELLS. CELULAS CALICIFORMES. CÉLULAS K562. K562 CELLS. CELULAS K562. ...

Cathepsin-activated near-infrared (NIR) imaging for intraoperative detection of insulinomas. A clinical trial evaluating a new ... Intraoperative assessment of marginal tissue after BCS resection using in-vivo topical application of a cathepsin-targeted ... Intraoperative detection of oral squamous cell carcinoma margins in dogs using cathepsin-activated near-infrared (NIR) imaging ...

Inflammatory stimuli recruit cathepsin activity to late endosomal compartments in human dendritic cells. Eur. J. Immunol. 32, ...

Cathepsin D. 6395. 16089. 33705. 11. Serpin E1/PAI-1. 16774. 23591. 702. ...

Name: cathepsin F. Type: Gene. Species: Mus musculus (mouse). Chromosome: 19. MGI: MGI:1861434 ...

Cathepsin B (2) Cathepsin D (2) Cathepsin E (1) Cathepsin G (2) ...

Tran, A., and Silver, J. (2021). Cathepsins in neuronal plasticity. Neural Regen. Res. 16, 26-35. doi: 10.4103/1673-5374.286948 ... and cathepsins are the putative endogenous proteases involved in degradation of ECMs (Page-McCaw et al., 2007; Mohamedi et al ...

Li R, Zhou R, Wang H, Li W, Pan M, Yao X, Zhan W, Yang S, Xu L, Ding Y and Zhao L: Gut microbiota-stimulated cathepsin K ... Cathepsin K (CTSK) mainly acts on bone remodeling and resorption. As the only upregulated metastasis-related signal in colon ... When the gut microbiota is altered, the lipopolysaccharide content, the expression of the cathepsin K gene and the risk of ...

Deficiency of cathepsin A, see Galactosialidosis. *Deficiency of cytochrome-b5 reductase, see Autosomal recessive congenital ...

... and cathepsin D (Figure 6). Cathepsin D was increased in cells treated with 0.5 and 0.8 mg/ml bevacizumab, with a more ... The main biologic function of cathepsins is to degrade cellular and extracellular proteins [26]; deregulation of cathepsin ... Expression of MMP-2 and cathepsin D increased in RPE cells incubated with bevacizumab. TIMP-1 binds to the active form of MMPs ... In summary, our experiments demonstrated the expression of MMP-2, TIMP-1, cathepsin D, VEGFA, CTGF, and α-SMA in RPE cells and ...

Cathepsin L and B as potential markers for liver fibrosis: Insights from patients and experimental models. ,p,Cathepsin L (CTSL ...

Inhibition of Cathepsins to Treat Neuroblastoma Alfred I duPont Hospital for Children / Robert Mason Innovation Grants 2008 ...

When a cathepsin cleaves an Ebola surface protein, it allows the virus to enter and infect the cell. Previous studies in mice ... To invade a cell, Ebola takes advantage of enzymes known as cathepsins that are part of the cells machinery for breaking down ... The researchers began their work with a known cathepsin inhibitor named E64. Related compounds appear to be nontoxic and have ... Once the molecules get into the acidic, intracellular compartments known as lysosomes, where cathepsins work and the virus acts ...

Cathepsin G; Cathepsins/metabolism; Cells, Cultured; Chemical and Drug Induced Liver Injury/pathology*; Chemotaxis, Leukocyte/ ...

1994) Redesign of the substrate specificity of human cathepsin D: The dominant role of position 287 in the S2 subsite. Protein ... 1994) Redesign of the substrate specificity of human cathepsin D: The dominant role of position 287 in the S2 subsite. Protein ... 1991) Comparison of kinetic properties of native and recombinant human cathepsin D. Adv. Exp. Med. Biol. 306, 343-347. [ ... 1991) Comparison of kinetic properties of native and recombinant human cathepsin D. Adv. Exp. Med. Biol. 306, 343-347.] ...

Role of cathepsin B-mediated apoptosis in fulminant hepatic failure in mice ...

Cathepsin B (1) Cathepsin D (1) Cathepsin E (1) Cathepsin K (1) ...

Cathepsin A Cathepsin B Cathepsin D Cathepsin E CCL2 CD39 Chil3 Cortisol C-Peptide Cystatin C Cystatin D DbH DPP4 ENPP6 FAP Flt ...

Seeing Cathepsin The activity of cathepsins, cysteine proteases involved in a number of stages of tumor development, is ...

Overexpression of Cathepsin F, Matrix Metalloproteinases 11 and 12 in Cervical Cancer. BMC Cancer (2005) 5:68. doi: 10.1186/ ...

Cathepsin-B activity. Cathepsin-B measurements were carried out in a "real-time" assay as described by Linebaugh and colleagues ... A cathepsin-B inhibitor, CA074, was added at a final concentration of 10 μmol/L to confirm that the activity measured was due ... Metastases and cathepsin B activity. A, at time of sacrifice, animals in the survival experiment shown in Fig. 1C were ... Metastases and cathepsin B activity. A, at time of sacrifice, animals in the survival experiment shown in Fig. 1C were ...

Effects of Cathepsin S Inhibition in the Age-Related Dry Eye Phenotype PDF ... TAGS: aging, cathepsins, dry eye syndromes, mice, phenotype, diet Invest. Ophthalmol. Vis. Sci.. 2023; 64(11):7. https://doi. ...

Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity. Katia Vancompernolle (UGent) , F VAN ...

8. Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression. Stress-resistant Translation of Cathepsin L ... 5. Conditional Gene Targeting Cell Type-Specific Roles of the Lysosomal Protease Cathepsin L in Mammary Tumor Progression.. ...

... as explained by cathepsin C-independent pathways [5, 9]. The role of cathepsin C could be the reason for the multiple cancer ... Cathepsin C, also known as dipeptidyl peptidase I, removes the N-terminal dipeptide pro-domain from several serine proteases, ... Since this is not the first case of skin cancer in PLS patients, we are supporting the possibility that cathepsin-C play a role ... Papillon-Lefèvre syndrome, Cathepsin-C, Basal cell carcinoma, Palmoplantar keratoderma, Early-onset periodontitis ...

Green tea has a functional chemical content called cathepsin. It shows anti-inflammatory and anti-oxidant effects, which are ...