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*  Active Caspases and Cleaved Cytokeratins Are Sequestered into Cytoplasmic Inclusions in Trail-Induced Apoptosis | JCB
TRAIL Initiates a Caspase Cascade with Caspase-8 at the Apex. Our demonstration of an early cleavage of caspase-8 and Bid, ... Caspases can be divided into two classes: (1) initiator caspases, with long prodomains, such as caspases-8 and -9, which either ... Cleavage of caspase-8 and its preferred substrate, Bid, preceded processing of caspases-7 and -9, indicating that caspase-8 is ... indirect activation of caspase-9, and downstream effector caspases. Cleavage of Bid, a caspase-8 substrate, only previously has ...
http://jcb.rupress.org/content/148/6/1239
*  Survivin mRNA 表达与卵巢癌相关性的 Meta 分析 中国循证医
An anti-apoptotic protein human a survivin is a direct inhibitor of caspase-3 and -7. Biochemistry, 2001, 40(4): 1117-1123. ... 2.3.3 不同临床分期的比较 共纳入 9 个研究[4-11,13],其中卵巢癌临床 Ⅰ~Ⅱ 期组 149 例,临床 Ⅲ~Ⅳ 期组 297 例。固定效应模型 Meta 分析结果显示,两组间 Survivin mRNA 表达差异有统计学意义[OR=4.76 ... 卵巢癌位居女性常见恶性肿瘤的第六位和女性肿瘤死亡的第七位[1-3],
http://www.cjebm.com/article/10.7507/1672-2531.201611081
*  Caspase-3 (P42574) | InterPro | EMBL-EBI
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
http://www.ebi.ac.uk/interpro/protein/P42574
*  "Caspase-3" and docking - PubMed - NCBI
Molecular Docking Analysis of Caspase-3 Activators as Potential Anticancer Agents.. Kashaw SK, Agarwal S, Mishra M, Sau S, Iyer ... Pharmacophore Modeling, Docking and Molecular Dynamics Studies on Caspase-3 Activators Binding at β-Tubulin Site. Bhunia SS et ... Acteoside Binds to Caspase-3 and Exerts Neuroprotection in the Rotenone Rat Model of Parkinson's Disease. Yuan J et al. PLoS ... Pharmacophore modeling and docking studies on some nonpeptide-based caspase-3 inhibitors. Sharma S et al. Biomed Res Int. (2013 ...
https://www.ncbi.nlm.nih.gov/pubmed/?term=%22Caspase-3%22+and+docking
*  Anti-Caspase-3 antibody (ab90437) | Abcam
Rabbit polyclonal Caspase-3 antibody validated for WB, IHC and tested in Human, Mouse, Rat and Rabbit. Referenced in 16 ... Cleavage by granzyme B, caspase-6, caspase-8 and caspase-10 generates the two active subunits. Additional processing of the ... Active heterodimers between the small subunit of caspase-7 protease and the large subunit of caspase-3 also occur and vice ... associated with an increase in intracellular caspase activity. Fas therefore activates caspase-3 not only by inducing the ...
http://www.abcam.com/caspase-3-antibody-ab90437.html
*  Caspase 3 - Wikipedia
Caspase substrate specificity has been widely used in caspase based inhibitor and drug design. Caspase-3, in particular, (also ... caspase activity would kill cells indiscriminately. As an executioner caspase, the caspase-3 zymogen has virtually no activity ... Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive ... This protein cleaves and activates caspases 6 and 7; and the protein itself is processed and activated by caspases 8, 9, and 10 ...
https://en.wikipedia.org/wiki/Caspase_3
*  Anti-active Caspase-3 antibody (ab49822) | Abcam
Rabbit polyclonal active Caspase-3 antibody validated for WB, ICC/IF and tested in Human, Mouse and Rat. Referenced in 2 ... Cleavage by granzyme B, caspase-6, caspase-8 and caspase-10 generates the two active subunits. Additional processing of the ... Active heterodimers between the small subunit of caspase-7 protease and the large subunit of caspase-3 also occur and vice ... associated with an increase in intracellular caspase activity. Fas therefore activates caspase-3 not only by inducing the ...
http://www.abcam.com/active-caspase-3-antibody-ab49822.html
*  FW: caspase-3
This is in reply to , your , question about the caspase 3 and the annexin V staining. We are releasing , a kit , for the BrDU ... But the annexin V is also known to , work , with the caspase 3. This is not something that we routinely quality , control in , ... Maryalice , , , , , , ,Dear all , , , , , , , ,We have been using a anti-Caspase-3 rabbit polyclonal ab conjugated , , , ,with ... I appreciate your , information regarding cytokines and BRDU but, my comment was to answer a , question of Caspase-3 staining, ...
https://lists.purdue.edu/pipermail/cytometry/1999-October/014201.html
*  Re: caspase-3 immunohistochemistry
... From:. Geoff McAuliffe You might look at Gown and Willingham, J. Histochem. Cytochem. 50(4 ... We are unable to >get good results using an rabbit anti-mouse anti-caspase-3 antibody. >We try to stain formalin-fixed mouse ...
http://www.histosearch.com/histonet/Mar03A/Re.caspase-3immunohistoch.html
*  Caspase-3 Assay Kits
BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, etc. BioVisions products are currently being sold in more than 60 countries worldwide.
https://www.biovision.com/products/apoptosis-related-products/caspases/caspase-3/caspase-3-assay-kits.html
*  Caspase 3 (Apopain) Substrate 1r-z, fluorogenic
Cleavage of Rh110 peptides by caspases generates strongly fluorescent Rh110 that is monitored fluorimetrically at 510-530 nm ... caspase substrates are probably the most sensitive indicators widely used for the fluorimetric detection of various caspase ... Caspase-3 substrate and caspase-7 substrate; (Z-DEVD)2-Rh110; z-(Asp-Glu-Val-Asp)2-Rh110 ... Caspase 3 (Apopain) Substrate 1r-z, fluorogenic; Rh110 (rhodamine 110)-derived ...
https://www.anaspec.com/products/product.asp?id=29456&productid=11952
*  anti-Caspase 3 antibody | GeneTex
... caspase 3, apoptosis-related cysteine peptidase) for ELISA, IHC-P. Anti-Caspase 3 pAb (GTX31698) is tested in Human samples. ... Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive ... This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the ... caspase 3, apoptosis-related cysteine peptidase. Background. This gene encodes a protein which is a member of the cysteine- ...
http://www.genetex.com/Caspase-3-antibody-GTX31698.html
*  Caspase 3, the executioner of apoptosis: Novus Biologicals
Caspase-3 is known as an executioner caspase in apoptosis because of its role in coordinating the destruction of cellular ... Caspase-3 enzyme is a member of the family of endoproteases which regulate inflammation and apoptosis signaling networks. ... caspase-9, and granzyme B to generate the active heterodimer of caspase-3 subunits (1). ... Caspase-3 is known as an executioner caspase in apoptosis because of its role in coordinating the destruction of cellular ...
https://www.novusbio.com/antibody-news/antibodies/caspase-3-the-executioner-of-apoptosis
*  Caspase Colorimetric Assay │ Caspase 3 Colorimetric Assay Kits
The Caspase-3 and -8 Colorimetric Assays kits measure the proteolytic cleavage of the chromophore p-nitroanilide (pNA) by ... Caspase Colorimetric Assay Kits & Caspase Fluorescent Assay Kits. The Caspase-3 Colorimetric Assays measure the proteolytic ... Caspase Colorimetric and Fluorescent Assay Kits. The ApoAlert Caspase Assay Kits provide a simple and convenient way to detect ... Simultaneously profile multiple caspases *Perform the assay directly on cell lysates *Fast and easy: caspase colorimetric ...
http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Apoptosis_Kits_and_Reagents/Caspase_Profiling?sitex=10020:22372:US&PEBCL1=jkQwH6ObCWztOYzoxmWfoUbqxT&PEBCL1_pses=ZGF9611B9FF78AB745DC7AE69E77EBA674D89DCC300EC0ED9AE6FB511566BB10289C4F7A1B870592F00CBCA55F1ED3AD5DA5F518D4140AD7EC
*  Caspase Colorimetric Assay │ Caspase 3 Colorimetric Assay Kits
The Caspase-3 and -8 Colorimetric Assays kits measure the proteolytic cleavage of the chromophore p-nitroanilide (pNA) by ... The ApoAlert Caspase Profiling Plate measures the activation of four different caspases (caspase-2, -3, -8, and -9) using a ... Caspase Colorimetric Assay Kits & Caspase Fluorescent Assay Kits. The Caspase-3 Colorimetric Assays measure the proteolytic ... We offer caspase detection assays in two formats: assay kits and 96-well plates. The assay kits detect caspase activation by ...
http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Apoptosis_Kits_and_Reagents/Caspase_Profiling?sitex=10020:22372:US&PEBCL1=brr6T3ZJr2ZxcK27YO2uTZVB07&PEBCL1_pses=ZG3D11BE890CE399DA771AAB4F7C369DC940A52BE7B2A00156C6DE1E4B7B028095B2E08E9CAE5D0F58FB36DC9D1639C305D7B6251025805666
*  Fluidigm | Consumables | Anti-Cleaved Caspase 3 (5A1E)-172Yb-50 Tests
The 5A1E antibody reacts with the active cleaved form of caspase-3, a 32 kDa cysteine protease that is activated during the ... Anti-Cleaved Caspase 3 (5A1E)-172Yb-50 Tests. Caspase-3 (CPP32/Yama/apopain ) is a 32 kDa cysteine protease that is activated ... Caspase-3 is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear ... Caspase-3 also plays an important role in morphogenetic cell death during development of the mammalian brain. The 5A1E antibody ...
https://www.fluidigm.com/reagents/proteomics/3172023a-anticleaved-caspase-3--5a1e--172yb--50tests
*  Fluidigm | Consumables | Anti-Cleaved Caspase 3 (5A1E)-172Yb-25 µg
The 5A1E antibody reacts with the active cleaved form of caspase-3, a 32 kDa cysteine protease that is activated during the ... Anti-Cleaved Caspase 3 (5A1E)-172Yb-25 µg. Caspase-3 (CPP32/Yama/apopain) is a 32 kDa cysteine protease that is activated ... Caspase-3 is either partially or totally responsible for the proteolytic cleavage of many key proteins in the apoptotic pathway ... Caspase-3 also plays an important role in morphogenetic cell death during development of the mammalian brain. The 5A1E antibody ...
https://www.fluidigm.com/reagents/proteomics/3172027d-anti-cleaved-caspase-3-5a1e-172yb%E2%80%9425-g
*  Caspase 3 ELISA Kit (Caspase 3, Apoptosis-Related Cysteine Peptidase)</span...
Caspase 3 ELISA Kit Human for Cell Culture Supernatant, Cell Lysate. Published in 5 Pubmed References. , Order Caspase 3 ELISA ... Product Details Caspase 3 ELISA Kit References Images Handling Application Details Target Details back to top ... References for Caspase 3 Kit (ABIN6574178) Images Handling Application Details Target Details back to top ... Caspase 3 ELISA Kit (Caspase 3, Apoptosis-Related Cysteine Peptidase) Caspase 3 ELISA Kit (Caspase 3, Apoptosis-Related ...
https://www.antibodies-online.com/kit/6574178/Caspase+3,+Apoptosis-Related+Cysteine+Peptidase+CASP3+ELISA+Kit/
*  Caspase-3 Antibody (31A893) [DyLight 550] (NB100-56709R): Novus Biologicals
Mouse Monoclonal Anti-Caspase-3 Antibody (31A893) [DyLight 550]. Validated: WB, IHC, IHC-P. Tested Reactivity: Human. 100% ... As an effector caspase, caspase-7 is cleaved and activated by initiator caspases such as caspase-1 (1). Like other caspase ... Caspase 7 - A key effector of the apoptotic pathway. Caspase-7 is an effector caspase with important roles in mediating cell ... Caspase 11 - A proinflammatory caspase that induces the innate immune response. While known for their role in programmed cell ...
https://www.novusbio.com/products/caspase-3-antibody-31a893_nb100-56709r
*  Ethanol-induced caspase-3 activation in the in vivo developing mouse brain. - PubMed - NCBI
Ethanol-induced caspase-3 activation in the in vivo developing mouse brain.. Olney JW1, Tenkova T, Dikranian K, Muglia LJ, ... we document that ethanol intoxication of 7-day-old infant mice causes a widespread pattern of caspase-3 activation ...
https://www.ncbi.nlm.nih.gov/pubmed/11895372?dopt=Abstract
*  Caspases 3 and 7: Key Mediators of Mitochondrial Events of Apoptosis | Science
Caspases 3 and 7: Key Mediators of Mitochondrial Events of Apoptosis. By Saquib A. Lakhani, Ali Masud, Keisuke Kuida, George A ... Caspases 3 and 7: Key Mediators of Mitochondrial Events of Apoptosis. By Saquib A. Lakhani, Ali Masud, Keisuke Kuida, George A ... Caspases 3 and 7: Key Mediators of Mitochondrial Events of Apoptosis Message Subject. (Your Name) has forwarded a page to you ... We generated mice deficient in the two effectors, caspase 3 and caspase 7, which died immediately after birth with defects in ...
http://science.sciencemag.org/content/311/5762/847
*  Caspase-3 Assay Kit (Colorimetric) - (KA0740) - Products - Abnova
... is used for detecting the activity of caspases that recognize the sequence DEVD using colorimetric method. (KA0740) - Products ... Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive ... This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the ... Caspase-3 Assay Kit (Colorimetric) is used for detecting the activity of caspases that recognize the sequence DEVD using ...
http://www.abnova.com/products/products_detail.asp?catalog_id=KA0740
*  enzolife caspase 3 colorimetrik kit tissue homogenization: post #1
enzolife caspase 3 colorimetrik kit tissue homogenization - posted in Apoptosis, Necrosis and Autophagy: hi all, i will use ... enzolife caspase 3 colorimetrik kit tissue homogenization. Started by libra, Feb 15 2013 01:12 AM ...
http://www.protocol-online.org/forums/topic/28490-enzolife-caspase-3-colorimetrik-kit-tissue-homogenization/