Cardiac function and remodeling is attenuated in transgenic rats expressing the human kallikrein-1 gene after myocardial ... Expression of the kcnk3 potassium channel gene lessens the injury from cerebral ischemia, most likely by a general influence on ... Simvastatin acutely reduces myocardial reperfusion injury in vivo by activating the phosphatidylinositide 3-kinase/Akt pathway. ... Tumor necrosis factor-like weak inducer of apoptosis-induced neurodegeneration.. J Neurosci. 2004 Sep 22;24(38):8237-44.. ...
Brain natriuretic peptide supplementation can increase cardiac neovascularization in infarcted hearts by stimulating endogenous ... with B-type natriuretic peptide protects the heart from ischemia-reperfusion injury by inhibiting myocardial apoptosis The ... 2017) Preexisting endothelial cells mediate cardiac neovascularization after injury Journal of Clinical Investigation 127:2968- ... Balint, Z. et al. Double-stranded RNA attenuates the barrier function of human pulmonary artery endothelial cells. PLoS One 8, ...
Transcription factor GATA4-targeted compounds that have previously shown in vivo efficacy in cardiac injury models were tested ... JQ1 demonstrated the cooperative role of GATA4 and BRD4 in the modulation of chamber-specific cardiac gene expression. ... to improve subtype-specific differentiation of endogenous or exogenously delivered progenitor cells in order to promote cardiac ... regulatory networks by GATA4-targeted compounds modulating chamber-specific transcriptional programs in multipotent cardiac ...
... cardiac troponin (cTnT) and development of left ventricular developed pressure. After ischemia-reperfusion, hearts were ... Cardiac injury was assessed by measuring the release of creatine kinase (CK-MB), ... Results: MCS could attenuate the tendency of weight loss of the model rats. It could also improve glucose tolerance; reduce ... The number of cell apoptosis of submandibular gland in the NOD mice treated with CsA decreased compared with the control group ...
Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting C-Jun N-terminal ... Modulation of neuro-inflammation and vascular response by oxidative stress following cerebral ischemia-reperfusion injury. Curr ... acetaminophen appears to protect cardiac myocytes exposed to reperfusion injury via inhibition of the mitochondrial ... Hadzimichalis NM, Baliga SS, Golfetti R, Jaques KM, Firestein BL, Merrill GF: Acetaminophen-mediated cardioprotection via ...
Korkmaz A., Kolankaya D. Inhibiting inducible nitric oxide synthase with rutin reduces renal ischemia/reperfusion injury. Can. ... Arjumand W., Seth A., Sultana S. Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NFκB, TNF-α ... frequent administration of it may lead to cardiac toxicity observed by an increase in the activity of serum cardiac marker ... Rutin administration significantly offered cardioprotection and restricted infracts size in normal and diabetic rats (Annapurna ...
provides cardio-protection from I/R injury. The I/R+CAPE group showed reduced apoptosis, attenuated NO production, elevated ... on myocardial ischemia/reperfusion injury in rats.. Huang SS, Liu SM, Lin SM, Liao PH, Lin RH, Chen YC, Chih CL, Tsai SK.. ... Injury of myocardium caused by I/R includes cardiac contractile dysfunction, arrhythmias, as well as irreversible myocyte ... The effects of caffeic acid phenethyl ester (CAPE) on spinal cord ischemia/reperfusion injury in rabbits.. Ilhan A, Koltuksuz U ...
Additional Effects of Back-Shu Electroacupuncture and Moxibustion in Cardioprotection of Rat Ischemia-Reperfusion Injury. ... Oleanolic Acid Attenuates Insulin Resistance via NF-κB to Regulate the IRS1-GLUT4 Pathway in HepG2 Cells. ... In patients with CHD, MBM programs can lessen the occurrence of cardiac events, reduce atherosclerosis, and lower systolic ... cancers often return in more aggressive forms metastasising with an increased risk of apoptosis. In other words it makes things ...
... has been shown that in fibroblasts and endothelial cells caveolin-1 attenuates cardiac dysfunction after ischemia-reperfusion ... Mice lacking Cav-3 have an inability to be preconditioned to ischemic injury through ischemia preconditioning. Therefore, given ... Cav-3 presents itself as an interesting therapeutic target for inducing cardioprotection from ischemia. Following the finding ... TNFalpha and ceramide-mediated apoptosis. # beta-integrin. # SRC. # RhoA. # p53. # MAP kinase cascade. # VEGF. # Filamin-A. # ...
Therefore, the new probe could serve as a desirable molecular tool for the study of ischemia-reperfusion injury, cell apoptosis ... Hypothermia provides an effective neuro and cardio-protection in clinical settings implying ischemia/reperfusion injury (I/R). ... MITO cells, which is cardiac progenitor cells (CPCs) activated by the mitochondrial delivery of resveratrol with an anti- ... Moreover, exogenous expression of Sam50 remarkably attenuates APAP-induced liver hepatoxicity. Thus, our findings uncover the ...
Endothelial injury can trigger activation of the complement system, promoting inflammation and the development of endothelial ... Hematopoietic stem cell transplantation and associated risk factors precipitate endothelial injury, leading to HSCT-TMA and ... injury syndromes, ultimately leading to organ damage and failure. In particular, the lectin pathway of complement is activated ... other endothelial injury syndromes such as hepatic veno-occlusive disease/sinusoidal obstruction syndrome, idiopathic pneumonia ...
The tocotrienols also significantly alleviated the ischemia-reperfusion injury, and reduced infarct size in the ischemic region ... It exerted protection against myocardial injury by mitigating cardiac dysfunction and oxidative injury in rats and also by the ... Such response was attenuated by calcium chelators, ethylene glycol tetraacetic acid (EGTA) and 1,2-bis(o-aminophenoxy)ethane- N ... Sun W, Wang Q, Chen B, Liu J, Liu H, Xu W: Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is ...
3 dioxygenase in beneficial effects of stem cells in hind limb ischemia reperfusion injury Cardiac BIN1 folds T-tubule membrane ... restores T cell immunity and immunotherapy against cancers MiR322 mediates cardioprotection against ischemia/reperfusion injury ... IFNγ NK cells drive LAMP1 TRAIL anti-inflammatory astrocytes Targeting OCT3 attenuates doxorubicin-induced cardiac injury ... apoptosis, and mitochondrial energetics Association of monogenic and polygenic risk with the prevalence of open-angle glaucoma ...
Melatonin Receptor 2 Mediates Melatonin-Conferred Cardioprotection Against Myocardial Ischemia/Reperfusion Injury DOI: 10.1097/ ... Dexmedetomidine attenuates acute stress-induced liver injury in rats by regulating the miR-34a-5p/ROS/JNK/p38 signaling pathway ... Regulation of Apoptosis TGF-β Signaling Pathway VEGF Signaling Pathway Wnt Signaling Pathway Research Topics. Cancer Research ... Apigenin Improves Hypertension and Cardiac Hypertrophy Through Modulating NADPH Oxidase-Dependent ROS Generation and Cytokines ...
2012) Cardioprotection of electroacupuncture against myocardial ischemia-reperfusion injury by modulation of cardiac ... 2013) Electroacupuncture acutely improves cerebral blood flow and attenuates moderate ischemic injury via an endothelial ... 2019) Effect of electroacupuncture at the ST36 and GB39 acupoints on apoptosis by regulating the p53 signaling pathway in ... Cerebral ischemia-reperfusion injury is an important area in which acupuncture was applied. In a previous study [57], laser ...
Cardiac myocyte cell death by apoptosis accompanies heart disease of both ischemic and nonischemic origin... ... in apoptosis pathways of cardiac myocytes exposed to redox stress, acidosis and simulated ischemia with and without reperfusion ... Li J, Yang C, Wang Y (2021) miR‑126 overexpression attenuates oxygen‑glucose deprivation/reperfusion injury by inhibiting ... 2019) Immune cells as targets for cardioprotection: new players and novel therapeutic opportunities. Cardiovasc Res 115(7): ...
... exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial ... 2018.05 - D. Coffee for cardioprotection and longevity.pdf. * 2018.06 - E. Coffee consumption and reduced risk of ... 2007.01 - C. Induction of apoptosis by calcium D-glucarate in 7,12-dimethyl benz [a] anthracene-exposed mouse skin.pdf ... 2017.11 - E. Neuroprotective effects of allicin on ischemia-reperfusion brain injury.pdf ...
Preoperative Fasting confers protection against intestinal ischaemia/reperfusion injury by modulating gut microbiota and their ... Assessment of the Cardioprotection Offered by Fisetin in H2O2-induced Zebrafish (Danio rerio)-Tg (cmlc2: egfp) ... Fangchinoline induces apoptosis, autophagy and energetic impairment in bladder cancer. *The antidiabetic agent acarbose ... Sodium butyrate attenuates rotenone-induced toxicity by activation of autophagy through epigenetically regulating PGC-1α ...