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View of Prevalence of resistance to second-line tuberculosis drug among multidrug-resistant tuberculosis patients in Viet Nam,...
AM, Amikacin; CM, Capreomycin; E, Ethambutol; FLDs, first-line TB drugs; H, Isonoazid; KM, Kanamycin; OFL, Ofloxacin; R, ... Of those, 15 cases (17.9%) had ofloxacin resistance and 6.0% were resistant to kanamycin and capreomycin. Five MDR-TB cases ( ... DST of second-line drugs (ofloxacin, amikacin, kanamycin, capreomycin) was performed on isolates from MDR-TB cases to identify ... Molecular analysis of cross-resistance to capreomycin, kanamycin, amikacin, and viomycin in Mycobacterium tuberculosis. ...
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400 mg 10 x 10 1 tablet 130 nd104a capreomycin inj. 750mg 1 vial 1 vial amp/vial 131 nd104b capreomycin injection 1g 1 vial 1 ... capreomycin inj. capreomycin injection tobramycin and dexamethasone 0.3%+0.1% pyridoxine hydrochloride (vit b6) tablet ip ... 127 nd104a capreomycin inj. 128 nd104b capreomycin injection 129 d750 tobramycin and dexamethasone 0.3%+0.1% 130 d447 ... ip 160 d200 methyl ergometrine 125mcg tablet ip 161 nd104a capreomycin inj. 162 nd104b capreomycin injection 163 nd68 inj ...
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... amikacin and capreomycin in participants with first-line drug resistance detected by Xpert or pDST were available in three ... amikacin and capreomycin. Phenotypic DST on solid culture (Löwenstein-Jensen) and for second-line drugs such as moxifloxacin or ... capreomycin, PAS, and prothionamide (representative for thiamids). Second-line DST was performed in MGIT and interpreted based ... capreomycin; TA, thionamide; LNZ, linezolid; BDQ, bedaquiline; CFZ, clofazamine ...
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... and capreomycin (CP). Field studies conducted. Reviewed by a WHO Expert Group in 2012; no public recommendation or discussion ... and capreomycin varied between 77.3% and 92.3% and was much lower for kanamycin at 42.7%. The sensitivity for the detection of ... for capreomycin and 56.3% and 56.0% for ethambutol."28 The assay performed well for ofloxacin, was less sensitive for kanamycin ... and capreomycin-resistance, and had low sensitivity and specificity for ethambutol-resistance. ...
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Eli Lilly Shares Technology Transfer Strategy for TB Drugs - DCAT Value Chain Insights
... cycloserine and capreomycin drug products); Vianex (capreomycin drug product); the Chao Center for Industrial Pharmacy ( ... As an example of the collaboration that resulted, it was determined that imported raw materials for capreomycin added to the ... The products transferred were: Hisun (capreomycin API and drug product); Shasun (cycloserine API); JSC (cycloserine drug ... Training other manufacturers to produce capreomycin and cycloserine involved technology transfer for the manufacturing ...
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... for capreomycin, and 80% and 100% for amikacin. The XDR-LFC solution appears to be a promising new tool for accurate detection ... for capreomycin, and 79.2% and 100% for amikacin, respectively. Whole-genome sequencing data for a subsample of 272 isolates ... and rrs for capreomycin and amikacin. We evaluated assay performance using direct sputum samples from 566 participants ... capreomycin and kanamycin resistance produced similar sensitivities and specificities to the WHO mutation catalogue. PCR-based ...