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*  N-Type Calcium Channels - N-Type Calcium Channel Summary Report | CureHunter
CALCIUM CHANNELS that are concentrated in neural tissue. Omega toxins inhibit the actions of these channels by altering their ... Channels, N-Type Calcium; Channels, Neural-Type Calcium; N Type Calcium Channel; N Type Calcium Channels; N Type VDCC; N Type ... N-Type Calcium Channel; Calcium Channels, N-Type; N-Type VDCC; N-Type Voltage-Dependent Calcium Channels; Calcium Channel, N- ... Type; Calcium Channels, N Type; Calcium Channels, Neural-Type; Channel, N-Type Calcium; ...
http://www.curehunter.com/public/keywordSummaryD020864-N-Type-Calcium-Channels-N-Type-Calcium-Channel.do
*  Single L-Type Calcium Channels in Smooth Muscle Cells From Resistance Arteries of Spontaneously Hypertensive Rats | Hypertension
Two types of calcium channels in single smooth muscle cells from rabbit ear artery studies with whole-cell and single-channel ... Single L-Type Calcium Channels in Smooth Muscle Cells From Resistance Arteries of Spontaneously Hypertensive Rats. Yusuke Ohya ... which inactivated the T-type Ca2+ channels as well as Na+ channels10; and (3) the channel opening disappeared with the ... Single-channel conductance of L-type Ca2+ channels was about 20 pS in both SHR and WKY. We used 50 mmol/L Ba2+ to record the ...
http://hyper.ahajournals.org/content/31/5/1125
*  T-TYPE CALCIUM CHANNEL BLOCKER - Patent application - There is provided a T-type calcium channel blocker that is a compound of...
Therefore, it is considered very useful to find T-type calcium channel blockers having a weak or little L-type calcium channel ... 0004]Recently, compounds having T-type calcium channel blocking action in addition to L-type calcium channel blocking action ... The T-type calcium channel blocker as set forth in 2., wherein Rb is C1-6alkyl group, CN or NH2;4. The T-type calcium channel ... calcium channel blockers, or therapeutic agents or preventive agents against diseases for which T-type calcium channel blocking ...
http://www.patentsencyclopedia.com/app/20100105636
*  Voltage-dependent L-type calcium channel subunit alpha-1S
The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage ... This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal ... Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a ... Compartment GO Terms for Voltage-dependent L-type calcium channel subunit alpha-1S. ...
https://pharos.nih.gov/idg/targets/Q13698
*  Molecular and functional study of splice variations of the L-type voltage-gated calcium channel CaV1.2 alpha1-subunit |...
L-type (CaV1.2) voltage-gated calcium channels play critical roles in membrane excitability, gene expression, cardiac and ... TANG ZHENZHI (2006-01-17). Molecular and functional study of splice variations of the L-type voltage-gated calcium channel ... Molecular and functional study of splice variations of the L-type voltage-gated calcium channel CaV1.2 alpha1-subunit. ... voltage-gated calcium channel; CaV1.2; alternative splicing; splice variant; cardiovascular system; Spontaneously Hypertensive ...
http://scholarbank.nus.edu.sg/handle/10635/121956
*  Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and...
Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and ... CalciumNeuroinflammationRyanodine receptorsL-type voltage-dependent calcium channelsSpatial memory ... Chavis P, Fagni L, Lansman JB, Bockaert J. Functional coupling between ryanodine receptors and L-type calcium channels in ... Epidemiological studies have shown that the use of L-type voltage-dependent calcium channel (L-VDCC) antagonists by patients ...
https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-015-0262-3
*  Localization of the gene encoding the |tex|$a {2}/\delta$|/tex|-subunits of the L-type voltage-dependent calcium-channel to...
subunits of the L-type voltage-dependent calcium-channel to chromosome 7q and analysis of the segregation of flanking markers ... Previously, we have excluded the genes encoding the skeletal muscle L-type voltage-dependent calcium channel alpha(1)-, beta(1 ... The demonstration of genetic heterogeneity in MHS prompted the investigation of the roles played by calcium regulatory proteins ...
https://repository.uantwerpen.be/link/irua/99879
*  Pharmaceuticals | Free Full-Text | Calcium Channel Blockers as Tocolytics: Principles of Their Actions, Adverse Effects and...
Their mechanism of action in tocolysis involves the blockade of L-type Ca2+ channels, influenced by the Ca2+-activated K+ ... channels, beta-adrenergic receptors (β-ARs) and sexual hormones. In clinical practice, most experience has been gained with the ... Dihydropyridine Ca2+ channel blockers (CCBs) are widely accepted in the treatment of premature labour. ... Kamp, T.J.; Hell, J.W. Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ. Res. 2000 ...
http://www.mdpi.com/1424-8247/6/6/689/htm
*  British Library EThOS: Using a functional tagged calcium channel to investigate trafficking
N-type calcium channels belong to the family of voltage gated calcium channels , which open in response to membrane ... These channels are responsible for the calcium influx that triggers neurotransmitter release at presynaptic terminals. N - type ... Understanding the regulation of N - type channels is critical to the development of treatments that target these channels. ... Although N - type channels are thought to consist of a Ca v 2.2, α 2 δ and β subunits, there is uncertainty over whether the ...
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634704
*  Ziconotide: Neuronal Calcium Channel Blocker for Treating Severe ...: Ingenta Connect
Keywords: analgesia; analgesic; conopeptide; conotoxin; n-type calcium channels; pain; prialt; snx-111; ziconotide ... the N-type calcium channel blockers, or NCCBs. Its novel mechanism of action as a non-opioid analgesic suggests ziconotide has ... therapeutic profile derives from its potent and selective blockade of neuronal N-type voltage-sensitive calcium channels ( ...
http://www.ingentaconnect.com/content/ben/cmc/2004/00000011/00000023/art00002
*  Action Potential Gating of Calcium Channels and Transmitter Release - OpenThesis
To test the hypothesis that individual N-type calcium channels open with a low probability, single channel recordings of N-type ... and L-type current activation. Using this approach I determined that N-type channels activate more slowly than L-type. ... I conclude from these studies that N-type voltage-gated calcium channels have a very low probability of opening (< 5%) during ... To understand how calcium current is activated physiologically, the activation and resulting current from N-type calcium ...
http://www.openthesis.org/documents/Action-Potential-Gating-Calcium-Channels-225784.html
*  International Union of Pharmacology. LI. Nomenclature and Structure-Function Relationships of Cyclic Nucleotide-Regulated...
CNG channels are also moderately sensitive to block by some other inhibitors of the L-type calcium channel (e.g., nifedipine), ... CNG cation channels are ion channels whose activation is mediated by the direct binding of cGMP or cAMP to the channel protein ... The extent of ligand discrimination varies significantly between the individual CNG channel types. Photoreceptor channels ... a classic L-type calcium channel blocker. These agents block Ih at concentrations comparable to ZD7288. Ivabradine is ...
http://pharmrev.aspetjournals.org/content/57/4/455
*  Human-gpDB
Voltage dependent P/Q type calcium channel-Homo sapiens. Description. "RecName: Full=Voltage-dependent P/Q-type calcium channel ... CALCIUM CHANNEL, VOLTAGE-DEPENDENT, P/Q TYPE, ALPHA-1A SUBUNIT; CACNA1A CALCIUM CHANNEL, L TYPE, ALPHA-1 POLYPEPTIDE, ISOFORM 4 ... Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage-gated calcium channel subunit alpha Cav2.1) (Calcium ... Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Voltage-gated calcium channel subunit alpha Cav2.1) (Calcium ...
http://schneider.embl.de/cgi-bin/human_gpdb.cgi?section=summary_sheet&gene=ENSG00000141837&category=effector&id=98
*  E-Type ATPase - Calcium Channel Mutations in Cardiac Arrhythmia Syndromes
Category: E-Type ATPase. Biomarker breakthrough discovery using mass spectrometry (Master of science) has recently. Published ...
http://www.researchdataservice.com/category/e-type-atpase/
*  T-Type Calcium Channels | Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors
... versions for these version research until a tissues type-specific cell series is created for multiple different carnivore types ... However the six web host cell lines had been derived from alternative tissues types (e.g. lung kidney uterus) which PCI-34051 ... 4 9 Hence Par6 regulates different biological processes most likely within a cell type and context-specific way. Par6 is ...
http://researchreport-digital.com/category/t-type-calcium-channels/
*  Anti-Calcium channel L type DHPR alpha 2 subunit抗体(ab42586)
Calcium channel L type DHPR alpha 2 subunit兔多克隆抗体(ab42586)可与人样本反应并经WB实验严格验证,被1篇 ... Anti-Calcium channel L type DHPR alpha 2 subunit抗体. 参阅全部 Calcium channel L type DHPR alpha 2 subunit 一抗. ... Dihydropyridine sensitive L type calcium channel subunits alpha 2/delta antibody. *L type calcium channel subunit alpha 2 ... Voltage dependent calcium channel subunit alpha 2/delta 1 antibody. *Voltage gated calcium
http://www.abcam.cn/calcium-channel-l-type-dhpr-alpha-2-subunit-antibody-ab42586.html
*  Neuroprotective effects of blockers for T-type calcium channels | Molecular Neurodegeneration | Full Text
... calcium channels such as L-type calcium channels and low-voltage activated calcium channels such as T-type calcium channels [7 ... Calcium homeostasis can be regulated by several types of calcium channels, including voltage-gated calcium channels (VGCCs). ... a blocker for L-type calcium channels, can protect neurons in the long-term culture model, while blockers for T-type calcium ... especially the role of excess calcium influx via L-type voltage-gated calcium channels and age-related changes in calcium ...
https://molecularneurodegeneration.biomedcentral.com/articles/10.1186/1750-1326-4-44
*  T-Type Calcium Channels | Application of Computational Methods for the Design of BACE-1 Inhibitors
T-Type Calcium Channels Furthermore to cellular immune system responses, humoral immune system responses, mediated. June 10, ...
http://world-of-links.com/category/t-type-calcium-channels/
*  P/Q type calcium-channel antibodies in paraneoplastic cerebellar degeneration with lung cancer. - Nuffield Department of...
Raised levels of P/Q type voltage-gated calcium-channel (VGCC) antibodies were found in 16 (41%) of 39 patients with ... P/Q type calcium-channel antibodies in paraneoplastic cerebellar degeneration with lung cancer. ... Raised levels of P/Q type voltage-gated calcium-channel (VGCC) antibodies were found in 16 (41%) of 39 patients with ... Animals, Autoantibodies, Biomarkers, Calcium Channels, N-Type, Cerebellum, ELAV Proteins, Female, Humans, Lambert-Eaton ...
https://www.ndcn.ox.ac.uk/publications/242547
*  Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels...
We conclude that palmitate increases alpha-cell exocytosis principally by enhanced Ca(2+) entry via l-type Ca(2+) channels and ... The latter effect was abolished by isradipine, suggesting that palmitate selectively modulates l-type Ca(2+) channels. The ... Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels ... Palmitate stimulation of glucagon secretion in mouse pancreatic alpha-cells results from activation of L-type calcium channels ...
https://www.rdm.ox.ac.uk/publications/19925
*  "Modulation of Voltage-Gated N-Type Calcium Channels by G Protein-Coupl" by Tora Mitra Ganguli
One of SP's downstream effects is to modulate N-type Ca2+ (N-) channels. While phospholipid breakdown is a part of the ... Despite the incomplete understanding of this modulation, pharmacological antagonists of both NK-1R and N-channels have been ... the role of this metabolic pathway has not been completely described with respect to N-channel modulation during pain signaling ... the SP signaling cascade that mediates inhibition of recombinant N-channel activity was characterized. By adopting a ...
http://escholarship.umassmed.edu/gsbs_diss/389/
*  Occupancy by oral administration of nicardipine of L-type calcium channels in rat brain | Pubblicazioni Scientifiche Unicam
Occupancy by oral administration of nicardipine of L-type calcium channels in rat brain. ... Occupancy by oral administration of nicardipine of L-type calcium channels in rat brain ... The occupancy of L-type Ca2+ channels by treatment with an oral dose of the dihydropyridine-type Ca2+ antagonist nicardipine ( ... The occupancy of L-type Ca2+ channels by treatment with an oral dose of the dihydropyridine-type Ca2+ antagonist nicardipine ( ...
https://pubblicazioni.unicam.it/handle/11581/117227
*  Gentaur Molecular :EIAab \ BIII,Brain calcium channel III,Cach5,Cacna1b,Cacnl1a5,Calcium channel, L type, alpha-1 polypeptide...
Calcium channel, L type, alpha-1 polypeptide isoform 5,Rat,Rattus norvegicus,Voltage-dependent N-type calcium channel subunit ... Calcium channel, L type, alpha-1 polypeptide isoform 5,Rat,Rattus norvegicus,Voltage-dependent N-type calcium channel subunit ... Calcium channel, L type, alpha-1 polypeptide isoform 5,Rat,Rattus norvegicus,Voltage-dependent N-type calcium channel subunit ... Calcium channel, L type, alpha-1 polypeptide isoform 5,Rat,Rattus norvegicus,Voltage-dependent N-type calcium channel subunit ...
http://www.antibody-antibodies.com/product2866349-search-BIII,Brain_calcium_channel_III,Cach5,Cacna1b,Cacnl1a5,Calcium_channel,_L_type,_alpha_1_polypeptide_isoform_5,Rat,Rattus_norvegicus,Voltage_dependent_N_type_calcium_channel_subunit_alpha_1B,Voltage_gat.html
*  Soluble substances released from postischemic reperfused rat hearts reduce calcium transient and contractility by blocking the...
Calcium, L-Type Calcium Channels, Myocardial Contraction, Myocardial Depressant Factor, Myocardial Reperfusion Injury, ... from postischemic reperfused rat hearts reduce calcium transient and contractility by blocking the L-type calcium channel ... from postischemic reperfused rat hearts reduce calcium transient and contractility by blocking the L-type calcium channel. ... and time-dependent gating of the L-type Ca 2+ channel. The postischemic coronary effluent modified neither the tissue ...
http://edoc.mdc-berlin.de/4742/
*  Differential Modulation of the Cardiac L- and T-type Calcium Channel Currents by Isoflurane | Anesthesiology | ASA Publications
Unlike the L-type calcium channel, the role of the cardiac T-type calcium channel contributes little to the Ca2+influx ... To compare the relative sensitivity of atrial L- and T-type calcium channels and ventricular L-type calcium channels to ... In addition, the atrial L-type calcium channels were more responsive to isoflurane than the ventricular L-type calcium channel ... the T-type calcium channel was less sensitive than the L-type calcium channel to isoflurane. 17 Previous studies from this ...
https://anesthesiology.pubs.asahq.org/article.aspx?articleid=1945089