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*  AID 1340429 - Selectivity ratio of IC50 for alpha1C/alpha2delta/beta1b L-type calcium channel (unknown origin) to IC50 for rat...
... to IC50 for rat brain alpha1B/alpha2b/beta1b N-type calcium channel. ... Selectivity ratio of IC50 for alpha1C/alpha2delta/beta1b L-type calcium channel (unknown origin) ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/1340429
*  AID 1084625 - Inhibition of L-type calcium channel in Rattus norvegicus Wistar (rat) thoracic aorta assessed as relaxation of...
Inhibition of L-type calcium channel in Rattus norvegicus Wistar (rat) thoracic aorta assessed as relaxation of KCl-induced ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/1084625
*  AID 415111 - Displacement of [3H]diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes by liquid...
... diltiazem from L-type calcium channel in Sprague-Dawley rat cardiac myocytes by liquid scintillation counting. ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/415111
*  AID 420019 - Antagonist activity at voltage dependent L-type calcium channel in New Zealand white rabbit sigmoid colon circular...
... colon circular smooth muscle strip assessed as induction of relaxation response in absence of Ca2+-activated potassium channel ... Antagonist activity at voltage dependent L-type calcium channel in New Zealand white rabbit sigmoid ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/420019
*  Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB. - PubMed - NCBI
Neurons express multiple types of voltage-gated calcium (Ca2+) channels. Two subtypes of neuronal L-type Ca2+ channels are ... Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.. Zhang H1, Fu Y, Altier C, ... CaV1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB ... CaV1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB ...
https://www.ncbi.nlm.nih.gov/pubmed/16706838?dopt=Abstract
*  Episodic Ataxia Type 2 - GeneReviews® - NCBI Bookshelf
Episodic ataxia type 2 (EA2) is characterized by paroxysmal attacks of ataxia, vertigo, and nausea typically lasting minutes to ... P/Q-type calcium channels are high voltage-activated calcium channels that are found primarily on neurons and are expressed at ... Functional implications of a novel EA2 mutation in the P/Q-type calcium channel. Ann Neurol. 2004;56:213-20. [PubMed: 15293273] ... Voltage-dependent P/Q-type calcium channel subunit alpha-1A. Familial Hemiplegic Migraine (FHM) Variation Database (CACNA1A). ...
https://www.ncbi.nlm.nih.gov/books/NBK1501/
*  Effect of American ginseng (Panax quinquefolius L.) on arterial stiffness in subjects with type-2 diabetes and concomitant...
... calcium channel blocker; cardiovascular disease; complementary and alternative medicine; diastolic blood pressure; fasting ... A total of 64 individuals with well-controlled essential hypertension and type 2 diabetes (gender: 22 M:42 F, age:63 ± 9.3 ... Effect of American ginseng (Panax quinquefolius L.) on arterial stiffness in subjects with type-2 diabetes and concomitant ... in type 2 diabetes patients with concomitant hypertension. ... Publication types, MeSH terms, Substances. Publication types. * ...
https://www.ncbi.nlm.nih.gov/pubmed/23973636
*  Mus musculus calcium channel, voltage-dependent, T type, alpha 1G subu - Nucleotide - NCBI
Mus musculus calcium channel, voltage-dependent, T type, alpha 1G subunit (Cacna... Mus musculus calcium channel, voltage- ... Mus musculus calcium channel, voltage-dependent, T type, alpha 1G subunit (Cacna1g), transcript variant 3, mRNA. NCBI Reference ... See the reference protein sequence for voltage-dependent T-type calcium channel subunit alpha-1G isoform c (NP_001171359.1). ... Calcium Regulation in the Cardiac Cell Calcium Regulation in the Cardiac CellCalcium is a common signaling mechanism, as once ...
https://www.ncbi.nlm.nih.gov/nuccore/NM_001177888
*  Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation. ...
... voltage gated calcium channel; MEK = mitogen-activated protein kinase kinase. ... Publication types, MeSH terms, Substances, Grant support. Publication types. *Research Support, N.I.H., Extramural ... mTOR = mammalian target of rapamycin; CAMKK = Calmodulin-dependent protein kinase kinase; CAMKII = calcium/calmodulin-dependent ...
https://www.ncbi.nlm.nih.gov/pubmed/21356521
*  Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes. - PubMed -...
... troponin T type 2 (TNNT2); calcium channel, voltage dependent, alpha 1C (CACNA1C). (B) 2D-PCA using mRNA signatures from 12 ... Publication types, MeSH terms, Substances, Secondary source ID, Grant support. Publication types. *Research Support, N.I.H., ... potassium channel, subfamily J2 (KCNJ2); sodium channel protein 5 alpha (SCN5A); sarco endoplasmic reticulum Ca2+ATPase 2 ( ... A few are labeled in the plot: troponin I type 3 (TNNI3); gap junction protein alpha 1 (GJA1); actin alpha cardiac muscle 1 ( ...
https://www.ncbi.nlm.nih.gov/pubmed/25964336
*  Crystal structure of the epithelial calcium channel TRPV6. - PubMed - NCBI
Binding of Gd3+ to TRPV6 was analyzed using models with one and two types of binding sites. A model with one type of binding ... channels TRPV5 and TRPV6 play vital roles in calcium homeostasis as Ca(2+) uptake channels in epithelial tissues. Detailed ... m-o, Comparison of calcium binding sites in TRPV6cryst (m), the engineered voltage gated Ca2+ channel CaVAb (n), and the ... Crystal structure of the epithelial calcium channel TRPV6.. Saotome K1, Singh AK1, Yelshanskaya MV1, Sobolevsky AI1. ...
https://www.ncbi.nlm.nih.gov/pubmed/27296226?dopt=Abstract
*  Identification of Symptomatic Fetuses Infected with Cytomegalovirus Using Amniotic Fluid Peptide Biomarkers. - PubMed - NCBI
The results also suggested the mechanistic implication of the T calcium channel alpha-1G (CACNA1G) protein in the development ... Publication type, MeSH terms, Substances. Publication type. *Research Support, Non-U.S. Gov't ... T calcium channel alpha-1G; MCM6, DNA replication licensing factor; TSC2, tuberin. ...
https://www.ncbi.nlm.nih.gov/pubmed/26808779
*  Marks AR[au] - PubMed - NCBI
Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing. ... Calcium release channel RyR2 regulates insulin release and glucose homeostasis.. Santulli G, Pagano G, Sardu C, Xie W, Reiken S ... Calcium release channel RyR2 regulates insulin release and glucose homeostasis.. Santulli G, Pagano G, Sardu C, Xie W, Reiken S ... Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging. ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Marks+AR%5Bau%5D&dispmax=50
*  Powell KL[au] - PubMed - NCBI
A Cav3.2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure ... Z944, a Novel Selective T-Type Calcium Channel Antagonist Delays the Progression of Seizures in the Amygdala Kindling Model. ... T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures. ... Low threshold T-type calcium channels as targets for novel epilepsy treatments. ...
https://www.ncbi.nlm.nih.gov/pubmed?access_num=Powell+KL&link_type=AUTHORSEARCH&cmd=search&term=Powell+KL%5Bau%5D&dispmax=50
*  ivana gadjanski - PubMed - NCBI
Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis. ...
https://www.ncbi.nlm.nih.gov/pubmed/?term=ivana+gadjanski
*  Flockerzi V[au] - PubMed - NCBI
L-type CaV1.2 calcium channels: from in vitro findings to in vivo function. ... Influence of the β2-Subunit of L-Type Voltage-Gated Cav Channels on the Structural and Functional Development of Photoreceptor ... Functional expression of calcium-permeable canonical transient receptor potential 4-containing channels promotes migration of ... Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Flockerzi+V%5Bau%5D&dispmax=50
*  Marsh KC[au] - PubMed - NCBI
Discovery of diphenyl lactam derivatives as N-type calcium channel blockers.. Doherty GA, Bhatia P, Vortherms TA, Marsh KC, ... Synthesis and SAR of 4-aminocyclopentapyrrolidines as orally active N-type calcium channel inhibitors for inflammatory and ... Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca²⁺ channel blockers with analgesic activity. ... Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with ...
https://www.ncbi.nlm.nih.gov/pubmed?cmd=search&term=Marsh+KC%5Bau%5D&dispmax=50
*  Dopamine D2 and adenosine A2A receptors regulate NMDA-mediated excitation in accumbens neurons through A2A-D2 receptor...
NMDAR, NMDA receptor; Cav1.3a, Cav1.3a L-type calcium channel; A2AR adenosine A2A receptor; D2R, dopamine D2 receptor; Golf, G- ... D2R-mediated suppression of NMDA-induced depolarized plateau is mediated by the suppression of Cav1.3a L-type calcium channel ... This modulation requires the physical interaction between scaffolding Shank proteins and Cav1.3a calcium channels through a ... Publication types, MeSH terms, Substances, Grant support. Publication types. *Research Support, N.I.H., Intramural ...
https://www.ncbi.nlm.nih.gov/pubmed?Db=pubmed&Cmd=ShowDetailView&TermToSearch=18800071
*  A randomized double-blind, placebo-, and active-controlled study of T-type calcium channel blocker ABT-639 in patients with...
T-type Cav3.2 calcium channels represent a novel target for neuropathic pain modulation. Preclinical studies with ABT-639, a ... In conclusion, treatment with the highly selective T-type Cav3.2 calcium channel blocker ABT-639 100 mg twice daily for 6 weeks ... A randomized double-blind, placebo-, and active-controlled study of T-type calcium channel blocker ABT-639 in patients with ... A randomized double-blind, placebo-, and active-controlled study of T-type calcium channel blocker ABT-639 in patients with ...
https://www.ncbi.nlm.nih.gov/pubmed/26067585
*  References for PMC Articles for PubMed (Select 21289290) - PubMed - NCBI
Calmodulin regulation and identification of calmodulin binding region of type-3 ryanodine receptor calcium release channel. ... Calcium-binding properties of wild-type and EF-hand mutants of S100B in the presence and absence of a peptide derived from the ... Simultaneous recording of intramembrane charge movement components and calcium release in wild-type and S100A1-/- muscle fibres ... Sarcoplasmic reticulum calcium release compared in slow-twitch and fast-twitch fibres of mouse muscle. ...
https://www.ncbi.nlm.nih.gov/pubmed?LinkName=pubmed_pubmed_refs&from_uid=21289290
*  Shuo Yu - PubMed - NCBI
Structure-Activity Analysis of N-Type Calcium Channel Inhibitor SO-3.. Dong M, Wang F, Yan Z, Yu S, Wei J, Wu Q, Liu Z, Tang Y ... Targeting of N-Type Calcium Channels via GABAB-Receptor Activation by α-Conotoxin Vc1.1 Variants Displaying Improved Analgesic ... A novel α-conopeptide Eu1.6 inhibits N-type (CaV2.2) calcium channels and exhibits potent analgesic activity. ...
https://www.ncbi.nlm.nih.gov/pubmed/?cmd=Search&term=Shuo%20Yu