Combined Effects of Soy Isoflavones and Docosahexaenoic Acid on Osteoclast Formation
RAW 264.7 cells were cultured with RANKL for 5 days. In mouse bone marrow cells, daidzein, genistein, and DHA significantly ... Mouse bone marrow cells were pre-cultured with macrophage colony-stimulating factor (M-CSF) for 3 days and then cultured with M ... In RAW 264.7 cells, daidzein tended to decrease and genistein significantly decreased the number of TRAP(+)MNCs, however, the ... Nuclear factor of activated T-cells c1 (NFATc1) mRNA expression tended to be decreased by daidzein, and was significantly ...http://www.sciepub.com/JFNR/abstract/6254
Climb For Life - 4. What is bone marrow hematopoietic stem cell transplant used for?
4. What is bone marrow hematopoietic stem cell transplant used for?. Published on 5 September 2012 in Information about ... Stem cells can be obtained not only from bone marrow but also from peripheral blood after a specific preconditioning of the ... With the expression "bone marrow hematopoietic stem cell transplant" we intend a complex procedure used especially, but not ... Indications for hematopoietic stem cell transplant are acute leukimias, chronic leukimias, different forms of bone marrow ...http://www.climbforlife.it/4-what-is-bone-marrow-hematopoietic-stem-cell-transplant-used-for/
Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic...
When certain stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red ... Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic ... allogeneic bone marrow transplantation Procedure: in vitro-treated bone marrow transplantation Phase 3 ... Arm II: Allogeneic bone marrow cells are subjected to CCE for T-lymphocyte depletion. The elutriation fractions are then ...https://clinicaltrials.gov/ct2/show/NCT00265837
Long-term endoscopic remission of Crohn disease after autologous stem cell transplantation for acute myeloid leukaemia
A favourable course of Crohn disease has been observed after allogeneic bone marrow transplantation, and there is now mounting ... Here, we present the first long-term endoscopic follow-up of a patient with Crohn disease undergoing autologous stem cell ... This case suggests that autologous stem cell transplantation can change not only the clinical course, but also the natural ... Long-term endoscopic remission of Crohn disease after autologous stem cell transplantation for acute myeloid leukaemia. ...http://liu.diva-portal.org/smash/record.jsf?pid=diva2:245496
High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous...
Procedure: autologous bone marrow transplantation Peripheral blood stem cells or bone marrow will be reinfused about 72 hours ... Procedure: autologous bone marrow transplantation Peripheral blood stem cells or bone marrow will be reinfused about 72 hours ... Autologous peripheral blood stem cells (PBSC) or bone marrow are reinfused on day 0. ... autologous bone marrow transplantation Procedure: peripheral blood stem cell transplantation Phase 3 ...https://clinicaltrials.gov/ct2/show/NCT00078988?term=stem+cell&rank=38
Management of graft-versus-host disease in paediatric bone marrow transplant recipients | IRIS UNIPV
In vitro T cell depletion in paediatric patients is usually reserved for those with transplants from partially matched family ... Management of graft-versus-host disease in paediatric bone marrow transplant recipients. ... Management of graft-versus-host disease in paediatric bone marrow transplant recipients ... In vitro T cell depletion in paediatric patients is usually reserved for those with transplants from partially matched family ...https://iris.unipv.it/handle/11571/108668
Bone Marrow Aspiration and Biopsy: The Test
... when bone marrow aspiration and/or biopsy tests are ordered, and what the results of a bone marrow aspiration or biopsy might ... Explains how bone marrow aspiration and biopsy tests are used, ... used to evaluate the blood cells within the bone marrow, as ... Formal name: Bone Marrow Aspiration; Bone Marrow Biopsy. Related tests: Complete Blood Count; WBC Differential; Reticulocyte ... The structure of the bone marrow, including the sponge bone (trabecular bone) ...https://labtestsonline.org/understanding/analytes/bone-marrow/tab/test
Autologous Stem Cell Transplant
Fortunately, the bone marrow can be "rescued" or replaced with stem cells. For autologous stem cell transplantation, stem cells ... The stem cells are collected form the bone marrow or peripheral blood, processed, frozen and stored. Since these cells are ... stem cells and the term autologous stem cell transplantation refers to either bone marrow or peripheral blood stem cell ... followed by the infusion of stem cells to "rescue" or restore bone marrow blood cell production. It is important to understand ...http://cancer.unm.edu/cancer/cancer-info/cancer-treatment/stem-cell-transplantation/autologous-stem-cell-transplant/
Bone marrow transplant expert recommends significant change- Fred Hutchinson Cancer Research Center
... experts is recommending a significant change to current transplant practice for patients who need marrow or adult stem cells ... asserts that bone marrow - not circulating, peripheral blood, which is the current norm - should be the source for unrelated ... donor adult stem cells for most patients who require a transplant. The reason: because there is less incidence of chronic graft ... One of the world's leading bone marrow transplant ... Collecting adult stem cells from bone marrow is a more invasive ...http://www.fredhutch.org/en/news/releases/2012/10/bone-marrow-transplant-expert-recommendation.html
Metastatic breast cancer with osteolytic skull lesions suspected to be multiple myeloma
Bone marrow examination revealed no increase in the number of plasma cells but normocellular bone marrow with involvement of ... Bone marrow biopsy revealed carcinoma cells that were positive for CA 15-3, estrogen receptor positive (51%-75%), and HER-2 (3+ ... monoclonal protein was not detected in serum and urine and the number of plasma cells was not increased in bone marrow ... also known as plasma cell myeloma is a B-cell malignancy characterized by abnormal proliferation of plasma cells which produce ...http://www.kjco.org/journal/view.php?number=291
The Mechanism of Osteoclast Differentiation Induced by IL-1 | The Journal of Immunology
Murine osteoclasts were prepared from bone marrow cells or splenocytes as previously described (21, 22). Spleen cells from c- ... floating cells were removed, and the attached cells, bone marrow-derived macrophages (BMMs), were used as osteoclast precursors ... Bone marrow cells were incubated for 3 days with M-CSF (30 ng/ml) alone or with M-CSF (30 ng/ml) plus TGF-β (1 ng/ml) to ... Koichi Matsuo (Keio University, Japan) (23). In brief, cells from bone marrow or spleens were cultured in α-MEM containing 10% ...http://www.jimmunol.org/content/183/3/1862
Role of the osteoclast in cranial suture waveform patterning - Byron - 2006 - The Anatomical Record - Wiley Online Library
Effect of alendronate treatment on the osteoclastogenic potential of bone marrow cells in mice. Bone 20: 335-340.. *CrossRef , ... It is a good assay for osteoclasts since they are bone marrow macrophages that utilize acid phosphatase to degrade bone ... Multinucleated TRAP-positive cells that were associated with the bone margin, especially when residing in a pit, were ... If suture bone growth did not slow after 6 weeks, then one could expect bony suture fusion since bone resorption is relatively ...http://onlinelibrary.wiley.com/doi/10.1002/ar.a.20322/full
HER2-Positive Circulating Tumor Cells Indicate Poor Clinical Outcome in Stage I to III Breast Cancer Patients | Clinical Cancer...
Micrometastatic breast cancer cells in bone marrow at primary surgery: prognostic value in comparison with nodal status. J Natl ... Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer. J Clin Oncol 2003;21: ... Isolated tumor cells in bone marrow three years after diagnosis in disease-free breast cancer patients predict unfavorable ... Circulating tumor cells in breast cancer: correlation to bone marrow micrometastases, heterogeneous response to systemic ...http://clincancerres.aacrjournals.org/content/12/6/1715
Minimal residual disease following autologous stem cell transplant in myeloma: impact on outcome is independent of induction...
Bone marrow (BM) aspirates for MRD assessment were obtained at the end of induction (n=252) and at day 100 post ASCT (n=397). ... Targeted next generation sequencing reveals high mutation frequency of CREBBP, BCL2 and KMT2D in high-grade B-cell lymphoma ... This phenomenon has also been clearly demonstrated in B-cell chronic lymphocytic leukemia (CLL) in the German CLL Study Group ... Briefly, we assessed 500,000 cells incubated with 6-color antibody combinations including CD138/CD38/CD45/CD19 with CD56/CD27 ...http://www.haematologica.org/content/101/2/e69
Pulmonary infiltrates following bone marrow transplantation
Focuses on bone marrow and stem cell transplantation. Definition of bone marrow transplantation; Comparison between allogeneic ... Bone marrow transplant. // Columbia Electronic Encyclopedia, 6th Edition;Q1 2017, p1 Bone marrow transplant: see bone marrow. ... Bone marrow transplant. // Columbia Electronic Encyclopedia, 6th Edition;Feb2013, p1 Bone marrow transplant: see bone marrow. ... Bone marrow and stem cell transplantation. Duncombe, Andrew // BMJ: British Medical Journal (International Edition);04/19/97, ...http://connection.ebscohost.com/c/articles/66014694/pulmonary-infiltrates-following-bone-marrow-transplantation
Cancer in Inherited Bone Marrow Failure Syndromes - Full Text View - ClinicalTrials.gov
Diamond-Blackfan anemia: pure red cell aplasia; elevated red cell adenosine deaminase. ... Pearson's Syndrome: malabsorption, neutropenia, marrow failure, metabolic acidosis; ringed sideroblasts.. Other bone marrow ... Cancer in Inherited Bone Marrow Failure Syndromes. This study is currently recruiting participants. See Contacts and Locations ... Other bone marrow failure syndromes.. *First degree relatives of IBMFS-affected subjects as defined here, i.e. siblings (half ...https://clinicaltrials.gov/ct2/show/NCT00027274?term=Thrombocytopenia&recr=Open&fund=01&rank=4
Bone marrow examination - Wikipedia
The bone marrow produces the cellular elements of the blood, including platelets, red blood cells and white blood cells. While ... Bone marrow examination refers to the pathologic analysis of samples of bone marrow obtained by bone marrow biopsy (often ... An Illustrated Guide to Performing the Bone Marrow Aspiration and Biopsy MedlinePlus: Bone marrow biopsy eMedicine: Bone Marrow ... Sometimes, a bone marrow examination will include both an aspirate and a biopsy. The aspirate yields semi-liquid bone marrow, ...https://en.wikipedia.org/wiki/Bone_marrow_examination
To determine if IL-6 is a factor implicated in the ex vivo bone marrow amplification observed in the presence of PTH and Flt-3L...
To figure out if IL-6 is a element implicated in the ex vivo bone marrow amplification noticed in the existence of PTH and Flt- ... Bone marrow was isolated and flow cytometric analyses of Annexin V+ cells ended up done. Graph of the share of Annexin V+ cells ... To further validate the IL-6 affect on hematopoietic cell expansion, bone marrow cells derived from wild-sort and IL-6 ... Complete bone marrow was isolated from wild-kind mice and seeded at 1.86105 cells/cm2 in the existence or absence of Flt-3L (a ...http://www.c14-demethylase.com/2016/12/28/to-determine-if-il-6-is-a-factor-implicated-in-the-ex-vivo-bone-marrow-amplification-observed-in-the-presence-of-pth-and-flt-3l-bone-marrow-cells-were-cultured-for-8-days-with-a-single-treatment-of-p/
Gonadal function after allogenic bone marrow transplantation for thalassaemia. Social integration of the older thalassaemic...
Gonadal function after allogenic bone marrow transplantation for thalassaemia. Social integration of the older thalassaemic ... cell-killing) drugs. These findings demonstrate that young thalassemic patients treated with chemotherapy for bone marrow ... Prior to bone marrow transplant, however, anticancer agents are administered to destroy the patient's bone marrow and suppress ... Evaluation, Complications and side effects, Physiological aspects, Bone marrow, Bone marrow transplantation, Gonads, Organ ...http://www.readabstracts.com/Health/Gonadal-function-after-allogenic-bone-marrow-transplantation-for-thalassaemia.html
different allogeneic graft accelerates white cell and platelet engraftment after T-cell-depleted bone marrow transplantation....
different allogeneic graft accelerates white cell and platelet engraftment after T-cell-depleted bone marrow transplantation. ... cells) of T-cell-depleted bone marrow cells from a single donor (C57BL/6 [H2(b)] or SJL/J [H2(s)]) and 2 units from different ... different allogeneic graft accelerates white cell and platelet engraftment after T-cell-depleted bone marrow transplantation. ... The beneficial effect of additional cells on peripheral T-cell counts were first observed on day +14. Cells both from donors ( ...https://scholars.duke.edu/display/pub673191
Phys.org - bone marrow cells
Various cell therapies involve injecting a specific cell type into a patient. These include, for example, bone marrow ... Stem cells also rust. Oxygen in the air is well known to cause damaging rust on cars through a process known as oxidation. ... Stem cell research could lead to treatment breakthroughs. Scientists have discovered a new way to replicate the regenerative ... Living color: Rainbow-hued blood stem cells shed new light on cancer, blood disorders. A new color-coding tool is enabling ...https://phys.org/tags/bone+marrow+cells/sort/date/all/
Bone marrow cells routinely help with wound healing
"We've known that bone marrow cells are involved in wound healing and inflammation - now we have data that shows bone marrow ... Bone marrow has been studied for a number of purposes in recent years because it is rich in stem cells - cells that can go on ... Researchers found green cells throughout the body, but observed that the highest concentration of bone marrow cells was in ... "What we have here is a new cell population that was not previously recognized," Isik said. "The bone marrow cells help form the ...http://www.innovations-report.com/html/reports/life-sciences/report-33141.html
Stem Cell Breakthrough: Bone Marrow Cells Are The Answer - Redorbit
"Our study shows that transplanted bone marrow cells fuse not only with bone marrow cells of the recipient, but with non- ... New research in the FASEB Journal shows that bone marrow cells fuse to different types of cells, including embryonic stem cells ... involves fusing bone marrow cells to embryonic stem cells. Once fused, the hybrid cells have DNA from both the donor and ... When bone marrow cells were engrafted into the recipient, they tested for the presence of both donor and recipient cells and ...http://www.redorbit.com/news/health/1815345/stem_cell_breakthrough_bone_marrow_cells_are_the_answer/
Bioengineered bone marrow cells let transplant recipients live drug-free | ZDNet
A mix of bioengineered cells can mean that transplant recipients no longer need to take a lifetime of anti-rejection drugs. ... Bone marrow stem cells were collected from donors.. *The team made those stem cells more 'transplant-friendly' by enriching ... Bioengineered bone marrow cells let transplant recipients live drug-free. A mix of bioengineered cells can mean that transplant ... Now, scientists have combined stem cells and other cells from bone marrow to promote a drug-free organ tolerance. ...http://www.zdnet.com/article/bioengineered-bone-marrow-cells-let-transplant-recipients-live-drug-free/
Malfunctioning bone marrow cells sabotage nerve cells in diabetes
Nerve cells that have not merged with the insulin-producing bone marrow cells remain intact and function normally. "Based on ... "These insulin-producing bone marrow cells are like terrorists that infiltrate the nerve-cell populations," he said. They ... Previously, Chan and members of his laboratory had found that bone marrow cells were among a group of cells in organs other ... They found that, in diabetes, only nerve cells that have fused with bone marrow cells display the abnormal function and ...http://www.innovations-report.com/html/reports/life-sciences/report-48122.html