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*  IJMS | Free Full-Text | Development of a Patient-Derived Xenograft (PDX) of Breast Cancer Bone Metastasis in a Zebrafish Model
A primary culture of bone metastasis derived from a 67-year-old patient with breast cancer was cultured and then injected into ... Our results underline the potential for using PDX models in bone metastasis research and outline new methods for the clinical ... which has the same hormonal receptor status as the bone metastasis primary culture, did not survive in the in vivo model. ... Bone metastasis is a complex process that needs to be better understood in order to help clinicians prevent and treat it. ...
http://www.mdpi.com/1422-0067/17/8/1375
*  7. Regulation of growth plate chondrocytes and bone cells
PDGF may play a role in bone development and growth, although little is known of the precise mechanism. PDGF gene expression ... b on bone cells have led to the hypothesis that TGF-b may have a role in the coupling of bone formation to bone resorption. One ... The factors in bone matrix responsible for this induction of bone formation were named the bone morphogenetic proteins (BMPs). ... During bone remodelling, FGF synthesised by osteoblasts and stored in bone matrix may be released following osteoclastic bone ...
http://archive.unu.edu/unupress/food2/UID06E/UID06E0V.HTM
*  British Library EThOS: CDKN2A : a predictive marker for bone mineral density or direct role in osteoblast function
... may be central to the mechanism by which early development influences bone mineral density and later bone health. Previous work ... As methylation of CDKN2A increases, bone mineral content, bone area and areal bone mineral density all decrease at both 4 and 6 ... between CDKN2A methylation at birth and later bone health could indicate a potential role for CDKN2A in bone development and ... of the variance seen in bone mineral densities between individuals. There is now increasing evidence that the development of ...
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.698364
*  The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation | BMC...
... impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and ... However, IGF1 stimulated bone growth to a similar degree in LY294002 treated bones (Figure 6B), with the ratio between the bone ... Golden LH, Insogna KL: The expanding role of PI3-kinase in bone. Bone. 2004, 34 (1): 3-12. 10.1016/j.bone.2003.09.005.View ... During endochondral bone development in the limb, growth plate chondrocytes undergo well-ordered and controlled phases of cell ...
https://bmcdevbiol.biomedcentral.com/articles/10.1186/1471-213X-8-40
*  Growth Plate Injuries - knee, leg - World of Sports Science
Every one of the long skeletal bones in the body has a growth plate that governs its rate of the bone growth and development. ... and the end of the bone. This injury presents a significant risk of permanently arresting development of the bone, due to the ... The period in physical development when the bones are at the greatest risk of a growth plate injury is near the end of puberty ... Type II is a fracture of the bone in part of the growth plate, and a crack of the bone shaft. This is the most common type of ...
http://www.faqs.org/sports-science/Fo-Ha/Growth-Plate-Injuries.html
*  Childhood Obesity's Invisible Cousin: Poor Bone Development | Runner's World
What you won't notice is a serious problem lurking below the surface.Research has shown that bone development increases ... After adolescence, it is difficult to significantly increase bone strength. ... The Iowa Bone Development Study recently measured activity levels and bone strength gains of 530 Iowa youth from age 5 to age ... A number of different bone measurements were taken to assess not just bone mass, but overall bone strength. ...
https://www.runnersworld.com/health-injuries/a20786056/childhood-obesitys-invisible-cousin-poor-bone-development/
*  Cscs: Mechanical stimulus crucial for bone development
Mechanical stimulus crucial for bone development. Researchers from ETH Zurich have successfully demonstrated, for the first ... encourages bone formation. However, it has remained unclear how exactly the bone-forming cells in the bone marrow respond to ... Moreover, bone resorption appears to be controlled mechanically to a considerably higher degree than bone formation, especially ... The resulting lack of oestrogen has a negative impact on bone formation and leads to bone resorption - presumably one of the ...
http://www.cscs.ch/index.php?id=1049
*  Capping off sesamoid bone development | Development
Sesamoid bones are small, flat bones that are embedded within tendons. To date, it has been thought that these bones develop ... Your Name) has sent you a message from Development Message Body (Your Name) thought you would like to see the Development web ... The authors further demonstrate that, similar to bone eminences - superstructures that mediate bone-tendon attachment - the ... Thank you for your interest in spreading the word on Development.. NOTE: We only request your email address so that the person ...
http://dev.biologists.org/content/142/10/e1001
*  IJMS | Free Full-Text | MicroRNAs Regulate Bone Development and Regeneration
... which have been reported to play a crucial role in maintaining bone development and metabolism. Osteogenesis originates from ... with diverse osteo-related genes and endeavor to sketch the contours of potential manipulations of miRNA-modulated bone repair. ... mesenchymal stem cells (MSCs) differentiating into mature osteoblasts and each period of bone formation is inseparable from the ... circuit between miRNAs and osteogenic homeostasis is of great value for artificial skeletal regeneration for severe bone ...
https://www.mdpi.com/1422-0067/16/4/8227
*  TRM Calphormin Growth & Bone Development Supplement for 🐴 Horses
Bone Development Supplement for Horses is available online with fast delivery from VioVet, the trusted supplier of veterinary ... However Calcium is not the only mineral integral to bone development. Calphormin contains other essential minerals to aid bone ... that combine to promote the optimal development of the skeleton, focusing on bone integrity. Ideal for pregnant mares and live ... I currently add limestone flour to the feed to aid bone formation and density. We are on clay with a high pH. How much better ...
https://www.viovet.co.uk/TRM_Calphormin_for_Horses/c9453/
*  Cellular Insights Into Bone Development
Researchers from Washington University looked within collagen fiber to investigate how new teeth and bones are formed to find ... Majority of the population will go day to day in their routines without thinking twice about their teeth and bones until there ... Majority of the population will go day to day in their routines without thinking twice about their teeth and bones until there ... new insights into faster bone healing and biomaterials. ... Bone and Dental Minerals Cellular Insights Into Bone ...
https://www.worldhealth.net/news/cellular-insights-bone-development/
*  Nutrition influences bone development from infancy through toddler years.
Nutritional factors that may contribute to bone accretion in infants and toddlers include maternal nutritional stat ... During the last decade a greater appreciation has developed for determining factors that influence bone accretion in healthy ... Bone Development / physiology*. Child, Preschool. Female. Humans. Infant. Infant Food. Infant Nutritional Physiological ... 14988469 - Nutrition influences bone development from infancy through toddler years.. 10569229 - Dietary nucleotides: effects ...
http://www.biomedsearch.com/nih/Nutrition-influences-bone-development-from/14988469.html
*  Frontiers | A review of hedgehog signaling in cranial bone development | Physiology
IHH expression is mainly found on the osteogenic fronts of the calvarial bones, and functions to induce cell proliferation and ... IHH expression is mainly found on the osteogenic fronts of the calvarial bones, and functions to induce cell proliferation and ... Nevertheless, SHH and IHH ligands are integral to cranial suture development and regulation of calvarial ossification. When HH ... the resultant suite of morphologic abnormalities highlights the important roles of HH signaling in cranial development. ...
https://www.frontiersin.org/articles/10.3389/fphys.2013.00061/full
*  Fish oil supplement in pregnancy improves child's muscle and bone development
... GETTY/ISTOCK ... Children whose mothers take fish oil supplements during pregnancy have more muscle and stronger bones in early childhood, a new ... and higher bone density than the children whose mothers took an olive oil placebo pill instead. ... bone, and fat mass suggesting a general growth stimulating effect." ...
http://www.iran-daily.com/News/230843.html
*  BONE DEVELOPMENT - SKELETAL SUPPORT - SUPPLEMENTS - HORSE CARE
Central Kentucky's largest supplier of horse, barn, and stable products for over 25 years. Offering free local delivery and over 4,000 horse, barn and stable products, KBC is a reliable, easy to find resource for the region or online.
https://www.kbchorsesupplies.com/horse-care/supplements/skeletal-support/bone-development.html
*  Bone Development in Young People | International Osteoporosis Foundation
During growth the gain in bone mineral mass is mainly due to an increase in bone size with very little change in bone density, ... life styles and genetics affect bone development in young people.. Body weight and bone health. The pursuit of a waif-like body ... in the amount of bone tissue within the bones. Just because a child is growing tall, this does not mean that his or her bone ... During growth, undernutrition, including insufficient caloric and protein intake, can severely impair bone development. ...
https://www.iofbonehealth.org/bone-development-young-people-0
*  The os priapiA study in bone development.
Several stages of development from the first appearance of the a d a g e of the bone t o its development into the defintive ... as the precursor of bone formation. Shipley ( '28) says, coricerniiig membrane bone, the development occurs in coniiective ... The os priapiA study in bone development.. код для вставки. код для вставки на сайт или в блог. Ширина: (. aвто. ). ... Jacob?; ( '24) describes the bone found in man as a 'fascia bone' occurring in the fibrous tissue of the tunica albuginea. It ...
https://www.docme.ru/doc/2181783/the-os-priapia-study-in-bone-development
*  preventive-bone-development-study | College of Dentistry and Dental Clinics
Preventive & Community Dentistry Research: Iowa Bone Development Study. The Iowa Bone Development Study (IBDS) was initiated in ... Assessments of bone development were made at ages 5, 9, 11, 13, 15 and 17. The study is currently completing bone assessments ... The study is assessing children's bone development over time through special, low radiation x-ray type procedures and relating ... years of bone development is yielding valuable information to help determine which factors are or are not contributing to bone ...
https://www.dentistry.uiowa.edu/node/237
*  Role of TCF/LEF Transcription Factors in Bone Development and Osteogenesis
... such as aberrant bone mass homeostasis. Development of novel therapies to normalize bone mass and correct developmental defects ... Li Z, Xu Z, Duan C, Liu W, Sun J, Han B. Role of TCF/LEF Transcription Factors in Bone Development and Osteogenesis. Int J Med ... J Bone Miner Metab. 2011;29:291-9 56. Hoeppner LH, Secreto F, Jensen ED, Li X, Kahler RA, Westendorf JJ. Runx2 and bone ... Komori T. Signaling networks in RUNX2-dependent bone development. J Cell Biochem. 2011;112:750-5 ...
http://www.medsci.org/v15p1415.htm
*  Bone development Flashcards by Jamie Baugh | Brainscape
These cells build up the matrix of the bone structure and also play a role in the mineralization of the bone matrix. Bone is ... Cells that dissolve bone mineral and matrix. Can absorb 8xthe amount of bone produced by an osteoblast. ... Long bones grow _______ by producing subperiosteal new bone and _______ by mineralizing cartilage at centers of ossification. ... The area where wider metaphyseal cancellous bone is actively remodeling to thinner diaphyseal cortical bone is called? ...
https://www.brainscape.com/flashcards/bone-development-4989832/packs/6997848
*  Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model
E. Araldi and E. Schipani, "Hypoxia, HIFs and bone development," Bone, vol. 47, no. 2, pp. 190-196, 2010. View at Publisher · ... Both VEGF and MMP-9 have been shown to play a central role in embryonic bone development and bone remodelling. The lack of ... We hypothesised that MH would result in decreased bone development in the fetus and thus reduced bone mass in adolescence. The ... When the bone volume was adjusted for body weight (bone volume/body weight), the relative bone volume was higher in MH compared ...
https://www.hindawi.com/journals/ije/2014/916918/
*  The Effects of Elk Velvet Antler Dietary Supplementation on Physical Growth and Bone Development in Growing Rats
The bone mineral density (BMD) is used to evaluate the bone mineral content (BMC) for a given bone volume and its measurement ... bone development parameters (including measurements of femur bone geometric and densitometric properties, dry matter content ... prevents bone loss and increases new bone formation in ovariectomized rats," Journal of Bone and Mineral Research, vol. 14, no ... As a whole, the observed positive effect of EVA on bone development in the present study is consistent with some of the account ...
https://www.hindawi.com/journals/ecam/2015/819520/
*  Postdoc: mechanobiology of bone development and regeneration - the Node
Postdoc: mechanobiology of bone development and regeneration. Posted by boerckel on October 25th, 2018 ... Willingness to apply for applicable postdoctoral fellowships and eagerness to take advantage of other career development ... Supportive mentorship for multi-faceted career development and opportunities tailored towards individual career goals. ... and development-mimetic tissue engineering. Projects feature a combination of cell and bioreactor culture, biomaterials, and ...
http://thenode.biologists.com/postdoc-mechanobiology-of-bone-development-and-regeneration/jobs/
*  Endochondral Bone Development infographic - LifeMap Discovery
Stages in bone formation. A-B. First, mesenchymal cells form condensed regions, where they differentiate into chondrocytes and ... G-I. Proliferating chondrocytes are constantly present in the developing bone and form the growth plate. Through the repeated ... Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative ... Cells of the outer perichondrium layer differentiate into osteoblasts, invade the hypertrophic zone and produce bone-specific ...
https://discovery.lifemapsc.com/library/images/endochondral-bone-development
*  Bone and Development | Felix Bronner | Springer
... presents the current knowledge of bone development, from growth to mineralization. Like ... the sixth in the series Topics in Bone Biology, ... Bone and Development. Editors. * Felix Bronner * Mary C. Farach ... cell signaling in growth plate and bone development, evolution of bone proteins and the interrelationship between bone and ... This volume, the sixth in the series Topics in Bone Biology, presents the current knowledge of bone development, from growth to ...
http://www.springer.com/us/book/9781848828216