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*  RWJMS - Departments and Institutes - Physiology and Biophysics
Effects of GABAA receptor blockade on regional cerebral blood flow and blood-brain barrier disruption in focal cerebral ... Effects of a PDGFR-a antagonist imatinib on blood-brain barrier disruption in focal cerebral ischemia in younger and older rats ... Effects of cannabinoid receptor agonist WIN 55,212-2 on blood-brain barrier disruption in focal cerebral ischemia in rats. ... Effects of blockade of ionotropic glutamate receptors on blood-brain barrier disruption in focal cerebral ischemia. Neurol. Sci ...
http://www.rwjms.rutgers.edu/neuroscience/faculty/Weiss.html
*  HIF prolyl hydroxylase inhibition prior to transient focal cerebral ischaemia is neuroprotective in mice. - Oxford Neuroscience
Mice receiving IOX3 at 20 mg/kg 24 h prior to the MCAO had better neuroscores and smaller blood-brain barrier (BBB) disruption ... that HIF stabilization with IOX3 before cerebral ischaemia is neuroprotective partially because of blood-brain barrier (BBB) ... IOX3 up-regulated HIF-1α, and increased EPO expression in mouse brains. In an in vitro BBB model (RBE4 cell line), IOX3 up- ... Pre-treating IOX3 on RBE4 cells 24 h before oxygen-glucose deprivation had a protective effect on endothelial barrier ...
https://www.neuroscience.ox.ac.uk/publications/475740
*  Posterior Reversible Encephalopathy Syndrome
... is a clinical syndrome that results from disruption of the blood-brain barrier and vasogenic edema, demonstrated on MRI with ... A labile blood pressure was normalized and seizures abated with fosphenytoin and levetiracetam. At 3 month of age, resolution ... The incidence of epilepsy was higher in men, younger patients with HE, and in those with brain disorders. [3] ...
https://www.pediatricneurologybriefs.com/articles/10.15844/pedneurbriefs-27-12-3/
*  blood-brain barrier - oi
blood-brain barrier' can also refer to... blood-brain barrier blood-brain barrier ... The mechanism that controls the passage of substances from the blood to the cerebrospinal fluid bathing the brain and spinal ... This barrier provides the central nervous system with a constant environment, while not interfering with the transport of ... blood-brain barrier blood-brain barrier n. blood-brain barrier n. The Blood-Brain Barrier ...
http://oxfordindex.oup.com/view/10.1093/oi/authority.20110803095512913
*  Free Radical Scavenger Edaravone Administration Protects Against Tissue Plasminogen Activator Induced Oxidative Stress And...
Blood-brain barrier (BBB) kit was used for evaluation of BBB in vitro. We examined neurovascular unit with immunocellular ... Bipolar Psychosis Brain Epilepsy Brain Infection Brain Injury Rehabilitation Brain Rehabilitation Brain Stimulation Brain ... Additive edaravone ameliorated such an oxidative damage by t-PA with protecting outer layers of blood-brain barrier (in vivo) ... edaravone administration protects against tissue plasminogen activator induced oxidative stress and blood brain barrier damage ...
https://www.omicsonline.org/proceedings/free-radical-scavenger-edaravone-administration-protects-against-tissue-plasminogen-activator-induced-oxidative-stress-and-blood-brain-barrier-damage-2672.html
*  PET Studies on P-Glycoprotein Function in the Blood-Brain Barrier: How it Affects Uptake and Binding of Drugs within the CNS |...
Permeability of the blood-brain barrier (BBB) is one of the factors determining the bioavailability of therapeutic drugs. The ... PET Studies on P-Glycoprotein Function in the Blood-Brain Barrier: How it Affects Uptake and Binding of Drugs within the CNS. ... Title: PET Studies on P-Glycoprotein Function in the Blood-Brain Barrier: How it Affects Uptake and Binding of Drugs within the ... Abstract: Permeability of the blood-brain barrier (BBB) is one of the factors determining the bioavailability of therapeutic ...
http://www.eurekaselect.com/61826/article
*  Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor...
T1 - Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor- ... Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor- ... Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin receptor- ... title = "Modulating the antibody density changes the uptake and transport at the blood-brain barrier of both transferrin ...
https://vbn.aau.dk/en/publications/modulating-the-antibody-density-changes-the-uptake-and-transport-
*  Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte...
... stress induces leukocyte-mediated cytokine release and blood-brain barrier failure in dynamic in vitro blood-brain barrier ... Mediators of blood-brain barrier dysfunction and formation of vasogenic brain edema. J. Cereb. Blood Flow Metab 8, 621-634. ... Blood Flow Metab 16, 1108-1119. Hawkins B. T. and Davis T. P. (2005) The blood-brain barrier/neurovascular unit in health and ... Brain Res. 787, 277-285. Belayev L., Busto R., Zhao W. and Ginsberg M. D. (1996) Quantitative evaluation of blood-brain barrier ...
http://cogprints.org/5393/
*  Cell-specific blood-brain barrier regulation in health and disease: a focus on hypoxia - Zurich Open Repository and Archive
Engelhardt, S; Patkar, S; Ogunshola, O O (2014). Cell-specific blood-brain barrier regulation in health and disease: a focus on ... The blood-brain barrier (BBB) is a complex vascular structure consisting of microvascular endothelial cells that line the ... The blood-brain barrier (BBB) is a complex vascular structure consisting of microvascular endothelial cells that line the ... Cell-specific blood-brain barrier regulation in health and disease: a focus on hypoxia ...
http://www.zora.uzh.ch/id/eprint/99596/
*  Methotrexate, Cyclophosphamide, and Etoposide Phosphate Given With Osmotic Blood-Brain Barrier Disruption Plus Dexamethasone...
with osmotic blood-brain barrier disruption. Patients also receive oral dexamethasone every. 6 hours on days 2-15 (followed by ... phosphate administered in conjunction with osmotic blood-brain barrier disruption and. dexamethasone and cytarabine in patients ... Delivered In Conjunction With Osmotic Blood-Brain Barrier Disruption (BBBD), With Intraventricular Cytarabine +/- Intra-Ocular ... Delivered In Conjunction With Osmotic Blood-Brain Barrier Disruption (BBBD), With Intraventricular Cytarabine +/- Intra-Ocular ...
http://www.knowcancer.com/cancer-trials/NCT00074178/
*  Optimisation of a flow-based human in vitro blood-brain barrier model to replace animal models for studying immunopathogenesis...
The bloodbrain barrier (BBB) is the specialised barrier that prevents viruses, bacteria and toxins from entering the brain, ... The blood-brain barrier (BBB) is the protective physiological barrier that prevents pathogens such as viruses entering the ... This project aims to develop a human cell-culture model of the blood-brain barrier, to replace the use of some animal studies. ... Patabendige, A. (2012) Toward a humanised alternative to the use of laboratory animals for blood-brain barrier research. ATLA ...
https://www.nc3rs.org.uk/optimisation-flow-based-human-vitro-blood%E2%80%93brain-barrier-model-replace-animal-models-studying
*  Most attempts to build up models of the blood-brain barrier (BBB) | Breast Cancer-derived Factors Stimulate Osteoclastogenesis
Most attempts to build up models of the blood-brain barrier (BBB). May 15, 2017 4:23 pm. \ by Randall Harvey ... Most attempts to build up models of the blood-brain barrier (BBB) have resulted in models with low transendothelial electrical ... "blood-brain hurdle" (BBB) (1). The BBB regulates transport of acts and nutrients being a hurdle Rilpivirine for uptake of ... Dickinson BBB model comprising a co-culture of bovine human brain capillary endothelial cells (BCEC) and Rilpivirine rat ...
http://cylch.org/most-attempts-to-build-up-models-of-the-blood-brain-barrier-bbb/
*  Targeting the PI3K Pathway in the Brain-Efficacy of a PI3K Inhibitor Optimized to Cross the Blood-Brain Barrier | Clinical...
Blood-brain barrier and chemotherapeutic treatment of brain tumors. Expert Rev Neurother 2006;6:1199-209. ... Targeting the PI3K Pathway in the Brain-Efficacy of a PI3K Inhibitor Optimized to Cross the Blood-Brain Barrier. Laurent ... Targeting the PI3K Pathway in the Brain-Efficacy of a PI3K Inhibitor Optimized to Cross the Blood-Brain Barrier ... Targeting the PI3K Pathway in the Brain-Efficacy of a PI3K Inhibitor Optimized to Cross the Blood-Brain Barrier ...
http://clincancerres.aacrjournals.org/content/18/22/6239?rss=1
*  EMF-Portal | Effect of mobile telephony on blood-brain barrier permeability in the fetal mouse brain.
2008): Blood-brain barrier permeability and nerve cell damage in rat brain 14 and 28 days after exposure to microwaves from GSM ... 2009): Increased blood-brain barrier permeability in mammalian brain 7 days after exposure to the radiation from a GSM-900 ... Effect of mobile telephony on blood-brain barrier permeability in the fetal mouse brain. med./bio. [Wirkung des Mobilfunks auf ... 2009): Effects of 915 MHz electromagnetic-field radiation in TEM cell on the blood-brain barrier and neurons in the rat brain. ...
https://www.emf-portal.org/de/article/13429
*  The effect of a stress-induced increase in blood brain barrier permeability on intracerebral gene expression - Lancaster EPrints
Curtis, Fiona and Behan, Wilhelmina and Gow, John (2001) The effect of a stress-induced increase in blood brain barrier ... The effect of a stress-induced increase in blood brain barrier permeability on intracerebral gene expression. ...
http://eprints.lancs.ac.uk/51962/
*  Characterization of the Blood Brain Barrier in Pediatric Central Nervous System Neoplasms - - ScopeMed.org - Deposit for...
Key words: blood brain barrier, pediatric brain tumor, glioma, pilocytic astrocytoma, medulloblastoma. ... Objective: The normal blood brain barrier (BBB) is composed of tight junctions between endothelial cells and surrounding ... Characterization of the Blood Brain Barrier in Pediatric Central Nervous System Neoplasms ... Breakdown of the physiological astrocyte-endothelial cell relationship occurs in adult metastatic and primary brain tumors. ...
http://www.scopemed.org/?mno=230722
*  Nanodelivery of cerebrolysin reduces functionalized Gold Nanoparticles induced Blood-brain barrier disruption, brain edema...
Blood-brain barrier (BBB) breakdown to Evans blue albumin (EBA 3 ml/kg, i.v.) and [131]-Iodine (100 µCi/kg, i.v.) was examined ... Marked BBB breakdown in several brain areas e.g., cerebral cortex, hippocampus, cerebellum, thalamus, hypothalamus and brain ... Brain edema and neuronal injuries were tightly correlated with BBB breakdown. Activation of astrocytes and neuronal damages ... Thus, it would be interesting to examine AuNPs neurotoxicity in vivo models in relation to size related effects on brain ...
http://www.techconnect.org/proceedings/paper.html?volume=TCB2017v3&chapter=3&paper=600
*  THE BLOOD-BRAIN BARRIER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER (SMVT): A MOLECULAR FUNCTIONAL IN VITRO - IN SITU CORRELATION...
THE BLOOD-BRAIN BARRIER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER (SMVT): A MOLECULAR FUNCTIONAL IN VITRO - IN SITU CORRELATION ... THE BLOOD-BRAIN BARRIER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER (SMVT): A MOLECULAR FUNCTIONAL IN VITRO - IN SITU CORRELATION ... THE BLOOD-BRAIN BARRIER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER (SMVT): A MOLECULAR FUNCTIONAL IN VITRO - IN SITU CORRELATION ... THE BLOOD-BRAIN BARRIER SODIUM-DEPENDENT MULTIVITAMIN TRANSPORTER (SMVT): A MOLECULAR FUNCTIONAL IN VITRO - IN SITU CORRELATION ...
http://dmd.aspetjournals.org/content/early/2005/07/20/dmd.105.005231
*  Chronic relapsing experimental allergic encephalomyelitis: relationships between autoantibody in cerebrospinal fluid, blood...
... blood-brain barrier permeability and pleocytosis. ANDREW F. WALLS, PHILIP W. BARON, MARTIN G. RUMSBY ... blood-brain barrier permeability and pleocytosis Message Subject (Your Name) has forwarded a page to you from Biochemical ... Chronic relapsing experimental allergic encephalomyelitis: relationships between autoantibody in cerebrospinal fluid, blood- ... Chronic relapsing experimental allergic encephalomyelitis: relationships between autoantibody in cerebrospinal fluid, blood- ...
http://www.biochemsoctrans.org/content/14/4/767
*  biOasis Discovers the Keys to Transcend to Advance Its Program for the Delivery of Therapeutics Across the Blood-Brain Barrier
... has identified a new family of peptides that conserve the brain shuttling properties of Transcend. Transcend is biOasis' ... a pioneering biopharmaceutical company focused on overcoming the limitations of therapeutic drug delivery across the blood- ... The blood-brain barrier represents the single greatest challenge in treating diseases and other disorders within the brain. ... can cross the blood-brain barrier to address unmet medical needs in the treatment of brain metastatic cancer and other brain ...
http://www.marketwired.com/press-release/bioasis-discovers-keys-transcend-advance-its-program-delivery-therapeutics-across-blood-tsx-venture-bti-1902723.htm
*  Effect of Essential Fatty Acid Deficiency & Immunopathological Stresses on Blood Brain Barrier (B-BB) in Lewis Rats: A...
Effect of Essential Fatty Acid Deficiency & Immunopathological Stresses on Blood Brain Barrier (B-BB) in Lewis Rats: A ... Effect of Essential Fatty Acid Deficiency & Immunopathological Stresses on Blood Brain Barrier (B-BB) in Lewis Rats: A ... Effect of Essential Fatty Acid Deficiency & Immunopathological Stresses on Blood Brain Barrier (B-BB) in Lewis Rats: A ... Effect of Essential Fatty Acid Deficiency & Immunopathological Stresses on Blood Brain Barrier (B-BB) in Lewis Rats: A ...
http://www.biochemsoctrans.org/content/22/3/338S
*  In Vivo Measurement of BloodBrain Barrier Permeability - Current Protocols
This unit describes various protocols for the in vivo quantitation of drug permeability across the rodent bloodbrain barrier ... Quantitation of bloodbrain barrier permeability. In Implications of the BloodBrain Barrier and Its Manipulation (E.A. Neuwelt ... Brain Barrier Influx Measurement: Simplified In Situ Brain Perfusion for Rats. *Basic Protocol 2: BloodBrain Barrier Influx ... Selective brain to blood efflux transport of para‐aminohippuric acid across the bloodbrain barrier:In vivo evidence by use of ...
http://www.currentprotocols.com/WileyCDA/CPUnit/refId-ns0719.html