Ontology:. What does this gene/protein do?. Show (47). FYN is implicated in:. - activated T cell proliferation - ATP binding - ... functional enrichment analysis was performed on each of the correlated set groups to discover any potentially shared biological ... We found that some cancer-related Gene Ontology terms and pathways (e.g. cell adhesion, cell surface receptor signaling pathway ... Database for Annotation, Visualization and Integrated Discovery online tools were used to obtain Gene Ontology analysis and the ...
Gene Ontology and Pathway Enrichment Analysis. KEGG pathway and gene ontology (GO) biological process (BP), molecular function ... P. S. Arunachalam et al., Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans. Science ... S14). Next, we interrogated biological pathways over-represented in each cluster of soluble analytes. We found that the "KEGG ...
Existing ontologies, such as the Gene Ontology and others in the Open (...) Biological and Biomedical Ontologies (OBO) Foundry ... Biological ontologies are used to organize, curate, and interpret the vast quantities of data arising from biological ... Semantics in Support of Biodiversity: An Introduction to the Biological Collections Ontology and Related Ontologies.Ramona L. ... we describe the motivation for and ongoing development of a new Biological Collections Ontology, the Environment Ontology, and ...
The next step is to identify clusters of gene-sets so that they can be assessed for biological themes. The specific clustering ... The latter can be used to highlight hierarchical overlaps (such as those present in the gene ontology). ... Gene-set clusters identified can be assessed for their biological similarities using text-mining approaches. Here, we perform a ... Biologists then have to search through these lists to determines emerging themes to explain the altered biological processes. ...
Gene ontology (GO) analysis is often used for large-scale functional enrichment studies examining biological processes (BP), ... E, F Neuroactive ligand-receptor interaction and pathway of the IL-17 signaling pathway [15,16,17]. GO: Gene Ontology; BP: ... A GO enrichment analysis bubble plot for biological processes (BP) showing number of genes vs. GO term; node size indicates ... In future work, we will study the correlations among estrogen, ERGs, and biological characteristics of THCA, such as tumor ...
Search for the metabolic pathway information (KEGG) and gene ontology (GO) annotation of biological process. [more] example: ... Search for the subcellular localization prediction by WolfPSORT, Target P, SOSUI, TMHMM PTS1, and gene ontology (GO) annotation ... EC number and gene ontology (GO) annotation of molecular function. [more] example: ...
Goodwin, A. (2010) Evolution and Anarchism in International Relations: The Challenge of Kropotkins Biological Ontology, Global ... However, the collective, as weve discussed, is also an important social ontology; the individual being more important than the ... these societies are distinct social ontologies, not reducible to the sum of the interests of the individuals (Goodwin; 2010; ...
I would have expected an ontology which reflects the biological taxonomy Kingdom - Phylum - Class etc. without the extra ... We aim to build a data hub with LOD to connect data in different biological fields to enhance search and use of data across the ... Because of a huge variety of biological studies focused on different targets, i.e., from molecules to ecosystem, data produced ... S1: Data lacks information about relationships as well as semantically rich descriptions (i.e., with ontologies).. - S1: Expand ...
Areas of research include designing clinical information systems, mining EHRs, ontology, systems biology, integrating clinical ... and biological data and facilitating multidisciplinary and translational science. New degree granting programs include ...
semantics and ontologies (e.g., sampling, traits);. *biological field station data management; ...
... biological interpretation of the RRR differential gene expression by literature mining, gene ontology (GO) analysis, and ... Among the biological functions of those genes are glycolysis (HK1 and PGK1) and the IGF-I pathway (IGFBP1 and IGFBP3; Tables 1 ... The biological functions of the concordant genes indeed support the view of "cancer as a wound" and include genes and pathways ... Discordant Genes and Biological Processes that Differentiate RRR from RCC. Nearly a fourth (23%) of the genes differentially ...
Ontology analysis revealed that more than twice the number of catalysis genes and more than 3.6-fold of metabolic genes were up ... To better understand mechanisms of acephate resistance, biological, biochemical, and molecular experiments were systematically ... To better understand acephate resistance mechanisms, biological, biochemical, and molecular experiments were systematically ... as compared to those down-regulated with the same molecular and biological functions. The large portion of metabolic or ...
Their results showed that genes from the same Gene Ontology Biological Process (GO-BP) category - which indicates the ...
... biological ontology tools, and a set of standard operating procedures. ... The project receives its main funding from the Biological Databases and Informatics program of the National Science Foundation ... Morphbank is an open web repository of biological images documenting specimen-based research in comparative anatomy, ... semantics and ontologies in the context of digital resource repositories. NESCent collaborates with Dr. Jane Greenbergs group ...
Authentication of Key Biological and/or Chemical Resources: For projects involving key biological and/or chemical resources, ... Wherever possible, community-standard formats, vocabularies, ontologies, quality metrics are used.. * Plans for sharing ... standard operating procedures for biological sample collection and preservation, information about biological sample consents, ... Selection of Biological Samples, Genomic Data and Genomic Data Sharing: In order to maximize the utility of the IGVF Consortium ...
... regulatory networks associated with response to water stress in Brachiaria nad developing genotype and phenotype ontologies for ...
It combines parts of several biological ontologies, covering domains such as anatomy, disease and chemical compounds. The EFO ... Getting Lucky in Ontology Search: A Data-Driven Evaluation Framework for Ontology Ranking. Proceedings of the 12th ... Prototyping a Biomedical Ontology Recommender Service. Bio-Ontologies: Knowledge in Biology. , Stockholm, Sweden (2009). ... How Ontologies are Made: Studying the Hidden Social Dynamics Behind Collaborative Ontology Engineering Projects. Web Semantics ...
It combines parts of several biological ontologies, covering domains such as anatomy, disease and chemical compounds. The EFO ... Getting Lucky in Ontology Search: A Data-Driven Evaluation Framework for Ontology Ranking. Proceedings of the 12th ... How Ontologies are Made: Studying the Hidden Social Dynamics Behind Collaborative Ontology Engineering Projects. Web Semantics ... A generic ontology for collaborative ontology-development workflows. Lecture Notes in Computer Science (including subseries ...
Gene ontology (GO) terms make up a formal vocabulary to describe gene functions. This network illustrates the biological ... Gene ontology enrichment analysis and protein-protein interaction network of differentially expressed genes. To identify the ... Gene ontology categories network of differentially transcribed genes. To characterize further the processes that are regulated ... Additional file 3: Table S2: Gene ontology enrichment results as executed by ErmineJ for the transcriptomes altered after ...
2004). Textpresso: an ontology-based information retrieval and extraction system for biological literature. PLoS Biol, 2(11), ... The Gene Ontology Consortium. (2019). The Gene Ontology resource: 20 years and still GOing strong. Nucleic Acids Res, 47(D1), ... The Gene Ontology in 2010: extensions and refinements The Gene Ontology Consortium. (2010). Nucleic Acids Res, 38(Database ... 2011). Worm Phenotype Ontology: integrating phenotype data within and beyond theC. eleganscommunity. BMC Bioinformatics, 12:32 ...
GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEGs, differentially expressed genes. (F) Heat map of histone ... Statistical significance was defined as an adjusted P value,0.05, and the biological significance was defined as a difference ... Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed using the Python ... Materials and Methods Reagents Ginsenoside Rg1 was obtained from Shanghai Yuan Ye Biological Technology Co., Ltd(B21057). The ...
NSF, Advances in Biological Informatics (ABI) Innovation: Authors in the drivers seat: fast, consistent, computable phenotype ... data and ontology production.. Start Date: July 2017. Completion Date: June 2020 ...
... and will be primarily fed by available biological/ mechanistic, toxicological/ epidemiological, physico-chemical and kinetic ... Ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk ... Data will be consecutively integrated in physiological maps, quantitative adverse outcome pathway networks and ontology ... ": "Ontology-driven and artificial intelligence-based repeated dose toxicity testing of chemicals for next generation risk ...
Gene Ontologies and Medline by automatically cross-referencing their respective data in a searchable, ontology-based network. ... It also merges over 40 naming systems, ending the frustration that comes from many names being applied to the same biological ... Experimental results can rapidly be put into biological/functional context, extracting real knowledge from data. Please take ...
Extensive computational and biological validation shows FpClass outperforms existing computational methods and most biological ... The annotation information is incorporated from several public pathway databases, Gene Ontology annotations as well as drug and ... It integrates different biological features using a novel taxonomy-based semantic similarity measure in predicting and ... T-WPPDC then uses a scoring function to discriminate different biological classes. We validated T-WPPDC by prediction of single ...
Approximately 904 protein species with 4774 Gene Ontology (GO) terms were grouped into the categories of biological process, ...
Approximately 904 protein species with 4774 Gene Ontology (GO) terms were grouped into the categories of biological process, ...
Approximately 904 protein species with 4774 Gene Ontology (GO) terms were grouped into the categories of biological process, ...
Biological Ontologies, Databases, Genetic, Gene Ontology, Phenotype, Schizosaccharomyces. UCL classification:. UCL. UCL , ... FYPO: the fission yeast phenotype ontology. Bioinformatics , 29 (13) 1671 -1678. 10.1093/bioinformatics/btt266. ... To provide consistent computable descriptions of phenotype data, PomBase is developing a formal ontology of phenotypes observed ...