In molecular biology, the auxin binding protein family is a family of proteins which bind auxin. They are located in the lumen ... Palme K, Hesse T, Campos N, Garbers C, Yanofsky MF, Schell J (February 1992). "Molecular analysis of an auxin binding protein ... 2002). "Crystal structure of auxin-binding protein 1 in complex with auxin". EMBO J. 21 (12): 2877-85. doi:10.1093/emboj/cdf291 ... which could represent a signal for translocation of the protein to the ER. The mature protein comprises around 165 residues, ...
Guanylate-binding proteins (GBP) fall into the last class. GBP genes have been universally recognized in mammalian as well as ... or additional domains that are thought to operate in protein-protein or protein-membrane interactions. Some GBPs have exhibited ... In molecular biology, the guanylate-binding proteins family is a family of GTPases that is induced by interferon (IFN)-gamma. ... Kim BH, Chee JD, Bradfield CJ, Park ES, Kumar P, MacMicking JD (May 2016). "Interferon-induced guanylate-binding proteins in ...
retinol-binding protein 4. Names. PRBP. RBP. plasma retinol-binding protein. retinol binding protein 4, plasma. retinol-binding ... lipocalin_RBP_like; retinol-binding protein 4 and similar proteins. * NM_001323518.2 → NP_001310447.1 retinol-binding protein 4 ... Visfatin and Retinol Binding Protein-4 in Young-Onset Type 2 Diabetes Mellitus. Title: Visfatin and Retinol Binding Protein-4 ... Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family. * NM_006744.4 → NP_006735.2 retinol-binding protein 4 ...
CAB39 calcium binding protein 39 [Homo sapiens] CAB39 calcium binding protein 39 [Homo sapiens]. Gene ID:51719 ... mRNA and Protein(s) * NM_001130849.2 → NP_001124321.1 calcium-binding protein 39 ... NM_001130850.2 → NP_001124322.1 calcium-binding protein 39. See identical proteins and their annotated locations for NP_ ... calcium binding protein 39provided by HGNC. Primary source. HGNC:HGNC:20292 See related. Ensembl:ENSG00000135932 MIM:612174; ...
First, they designed two Pumby proteins that would bind to adjacent RNA sequences. Each protein is also attached to half of a ... These RNA-binding proteins could also be used to build molecular assembly lines that would bring together enzymes needed to ... Hoping to make the assembly of RNA-binding proteins less of a trial-and-error and more programmable task, the MIT researchers ... The details appeared online the week of April 25 in PNAS, in an article entitled, "A Programmable RNA Binding Protein Composed ...
... protein is shown to depend on base sequence, 5′ AAG 3′ binding being the strongest of the 25 trinucleoside diphosphate ... From our binding constant data the most likely frame is predicted and shown to have two contiguous AAG sequences in a hairpin ... As TMV has a stoichiometry of three nucleotides per protein subunit, the sequence of TMV RNA suggested to be the nucleation ... The binding of trinucleoside diphosphates to long helical rods of tobacco mosaic virus (TMV) ...
... the immunoglobin Fc-binding site of the Z domain and the DNA-binding motif of MyoD bHLH, into a novel stable protein. ... In this work, we generated and optimized a new synthetic fusion protein using an evolutionary approach. The optimization was ... We have successfully combined two unrelated naturally occurring binding sites, ... Computational design of novel proteins with well-defined functions is an ongoing topic in computational biology. ...
Binding site differences revealed by crystal structures of Plasmodium falciparum and bovine acyl-CoA binding protein.. van ... Acyl-CoA binding protein (ACBP) maintains a pool of fatty acyl-CoA molecules in the cell and plays a role in fatty acid ... Acyl-CoA binding protein (ACBP) maintains a pool of fatty acyl-CoA molecules in the cell and plays a role in fatty acid ... The parasite ACBP is shown to have a different ligand-binding pocket, leading to an acyl-CoA binding specificity different from ...
... to design two novel proteins that bind to a protein found in influenza viruses, proving that computer designed proteins are ... to design two novel proteins that bind to a protein found in influenza viruses, proving that computer designed proteins are ... the protein.. Candidate proteins were tested using a highly efficient yeast-based assay, and two of the designed proteins, HB36 ... to design two novel proteins that bind to a protein found in influenza viruses, proving that computer... ...
... it is sufficient to enable binding comparison with high sensitivit … ... A new algorithm has been developed to compare binding sites in accurate, efficient and high-throughput manner. Though the ... PocketMatch: a new algorithm to compare binding sites in protein structures BMC Bioinformatics. 2008 Dec 17;9:543. doi: 10.1186 ... Inferring functional similarities between protein molecules by comparing their binding sites is still largely exploratory and ...
Specific RNA Binding Proteins. Specific RNA Binding Proteins. Non-specific and Specific RNA Binding Proteins Found to be ... Researchers from Case Western Reserve University School of Medicine have found unexpected similarities between proteins that ...
The tristetraprolin family of RNA-binding proteins (RBPs), which include Zinc Finger Protein 36 (ZFP36; commonly referred to as ... The Tristetraprolin Family of RNA-Binding Proteins in Cancer: Progress and Future Prospects Cancers (Basel). 2020 Jun 11;12(6): ... Mechanistically, these proteins function by binding to the AU-rich elements within the 3-untranslated regions of their target ... tristetraprolin (TTP)), Zinc Finger Protein 36 like 1 (ZFP36L1), and Zinc Finger Protein 36 like 2 (ZFP36L2), play key roles in ...
protein coding gene. Chr9:22243305-22302132 (-). 129S1/SvImJ MGP_129S1SvImJ_G0034485. protein coding gene. Chr9:19634790- ... protein coding gene. Chr9:18351566-18412100 (-). CAST/EiJ MGP_CASTEiJ_G0033489. protein coding gene. Chr9:19789440-19852725 (-) ... protein coding gene. Chr9:19946689-20009417 (-). C57BL/6NJ MGP_C57BL6NJ_G0034975. protein coding gene. Chr9:20415182-20491275 ... protein coding gene. Chr9:19823784-19884858 (-). NOD/ShiLtJ MGP_NODShiLtJ_G0034284. protein coding gene. Chr9:22774962-22842845 ...
At the same time, the binding to α-2-macroglobulin decreased. Within a week after delivery, the total protein binding of FAA ... Binding of Folic Acid to Serum Proteins: I. The Effect of Pregnancy Subject Area: Hematology , Oncology ... T. Markkanen, P. Himanen, R.-L. Pajula, S. Ruponen, O. Castrén; Binding of Folic Acid to Serum Proteins: I. The Effect of ... Binding of Folic Acid to Serum Proteins: II. The Effect of Diphenylhydantoin Treatment and of Various Diseases Acta Haematol ( ...
protein coding gene. Chr11:84723187-84761668 (-). 129S1/SvImJ MGP_129S1SvImJ_G0018873. protein coding gene. Chr11:86281519- ... protein coding gene. Chr11:85447190-85489193 (-). BALB/cJ MGP_BALBcJ_G0018813. protein coding gene. Chr11:83380155-83418346 (-) ... protein coding gene. Chr11:85723685-85766063 (-). PWK/PhJ MGP_PWKPhJ_G0017951. protein coding gene. Chr11:83337473-83376182 (-) ... protein coding gene. Chr11:85275036-85316070 (-). WSB/EiJ MGP_WSBEiJ_G0018233. protein coding gene. Chr11:85567073-85606132 (-) ...
Crystal structure of the DNA-binding protein Sso10a from Sulfolobus solfataricus ... The hyperthermophile protein Sso10a is a dimer of winged helix DNA-binding domains linked by an antiparallel coiled coil rod.. ... Possible DNA-binding interactions are discussed on the basis of comparisons to other winged helix proteins. The structure of ... Sso10a is a member of a group of DNA-binding proteins thought to be important in chromatin structure and regulation in the ...
Experimental phasing with vanadium and application to nucleotide-binding membrane proteins ...
... and next-generation sequencing readouts to provide a new platform for characterizing DNA-protein interactions. ... Swiss Team Looks to Market DNA-Protein Binding Assay for Transcription Factor, ChIP Applications Jan 19, 2017 , Andrew P. Han ... NEW YORK (GenomeWeb) - A new microfluidics-driven DNA-protein binding assay has its creators dreaming of launching a startup to ... The transcription factors bind to any number of DNA motifs in the library, those interactions are trapped, and then the readout ...
Protein Binding Assays Market categories the Global market by by Technology (Equillibrium Dialysis, Ultrafiltration, ... Table 2 Protein Binding Assay Market, By Technology, Protein Binding Vials/Tubes (Units). Table 3 Protein Binding Assay Market ... The adoption of protein binding assays in CROs is mainly driven by the need for cost-effective protein binding services. ... Table 31 APAC: Protein Binding Assay Market for Other End Users, By Country, 2016-2023 (USD Million). Table 32 Protein Binding ...
Theoretical calculation of protein-protein and protein-ligand binding free energies is a grand challenge in computational ... Studies for an extensive set of realistic protein-protein interaction systems and for specific protein-ligand binding systems ... to computing quantitative residue-specific contributions to protein-protein and protein-ligand binding free energies. The ... 2. Sun, Z.; Yan, Y.; Yang, M.; Zhang, J.Z.H., Interaction entropy for protein-protein binding. J. Chem. Phys., 2017. 146, ...
Mapping the complete protein target space of drugs and drug-like compounds, including both intended ... Mapping the complete protein target space of drugs and drug-like compounds, including both intended ... Kernel-based predictive modelling of drug-protein binding affinities. author: Anna Cichonska, Aalto University published: June ... Mapping the complete protein target space of drugs and drug-like compounds, including both intended "primary targets" as well ...
Protein binding affinities from first principles. Add to your list(s) Download to your calendar using vCal ... University of Cambridge , Talks.cam , Electronic Structure Discussion Group , Protein binding affinities from first principles ...
Binding Protein II" by people in Harvard Catalyst Profiles by year, and whether "Poly(A)-Binding Protein II" was a major or ... A poly(A) binding protein that is involved in promoting the extension of the poly A tails of MRNA. The protein requires a ... binding protein II no longer stimulates POLYADENYLATION. Mutations within a GCG repeat region in the gene for poly(A) binding ... The poly(A) binding protein is internalized in virus-induced vesicles or redistributed to the nucleolus during turnip mosaic ...
Identifying protein-RNA interactions and the binding preferences of RBPs are critical to unraveling the mechanism of post- ... we present a computational approach that integrates both structure and sequence contexts for protein-RNA binding prediction. We ... study suggests the great potential of our method as a practical tool for identifying novel protein-RNA interactions and binding ... empowered by a deep neural network that combines the sequence and structure information to achieve improved protein-RNA binding ...
... proteins. When these genes were missing, the researchers observed accumulations of protein within the cell - proteins that had ... How many different shuttles are needed to move all these proteins - in effect, around 30% of all the proteins in each cell? ... How many different shuttles are needed to move all these proteins - in effect, around 30% of all the proteins in each cell? ... Communications are carried out by proteins - both the numerous proteins that are situated on the cells outer membranes to ...
Periplasmic binding protein-like I [53822] (1 family) *. Family c.93.1.1: L-arabinose binding protein-like [53823] (12 proteins ... More info for Family c.93.1.1: L-arabinose binding protein-like. Timeline for Family c.93.1.1: L-arabinose binding protein-like ... Family c.93.1.1: L-arabinose binding protein-like appears in SCOP 1.59. *Family c.93.1.1: L-arabinose binding protein-like ... Lineage for Family c.93.1.1: L-arabinose binding protein-like. *Root: SCOP 1.57 *. Class c: Alpha and beta proteins (a/b) [ ...
FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity. Download ... FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity.. Mol ... "FK506-binding Protein 52 Phosphorylation: a Potential Mechanism for Regulating Steroid Hormone Receptor Activity." Molecular ... FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity. Mol ...
Dimeric binding of plant alkaloid ellipticine to human serum proteins. By Ferenc Zsila, Tamás Beke-Somfai ... The F1/S and A genetic variants of the protein bind ellipticine with comparable affinity albeit the distinct topography of ... Home / KnowledgeBase Articles / Dimeric binding of plant alkaloid ellipticine to human serum proteins ... Human serum albumin (HSA) binding of anticancer plant alkaloid ellipticine has been studied in conjunction with assessing its ...
The methyl-CpG-binding protein MeCP2 was discovered over 15 years ago as part of a search for proteins that selectively bind ... It is a nuclear protein that is largely chromatin-bound and has a strong preference for binding to methylated DNA sequences in ... The methyl-CpG-binding protein MeCP2 and neurological disease Adrian Bird Adrian Bird 1 ... Adrian Bird; The methyl-CpG-binding protein MeCP2 and neurological disease. Biochem Soc Trans 1 August 2008; 36 (4): 575-583. ...