Mix and match | New Scientist
patients had produced IgG4 antibodies with two different antigen-binding sites. capable of binding to both antigens at once. ... Some bind simultaneously to diptheria and tetanus toxins.. Others capture banana antigens and cat dander antigens. "There are ... antibody has a pair of molecular tweezers known as an antigen-binding site.. These grasp a specific target antigen, such as a ... The radioactively labelled antigens also. stuck to the test tube, showing that the antibodies were simultaneously bound to. ...
Increased Levels of Antigen-Bound beta-Amyloid Autoantibodies in Serum and Cerebrospinal Fluid of Alzheimer's Disease Patients
... for the determination of antigen-bound Aβ-autoantibodies (intact Aβ-IgG immune complexes) in serum and cerebrospinal fluid (CSF ... article{Maftei2013Incre-24148, year={2013}, doi={10.1371/journal.pone.0068996}, title={Increased Levels of Antigen-Bound beta- ... for the determination of antigen-bound Aβ-autoantibodies (intact Aβ-IgG immune complexes) in serum and cerebrospinal fluid (CSF ... for the determination of antigen-bound Aβ-autoantibodies (intact Aβ-IgG immune complexes) in serum and cerebrospinal fluid (CSF ...
EN (en)
Almost all human gastric mucin O-glycans harbor blood group A, B or H antigens and are potential binding sites for Helicobacter ... In order to define which glycans may be implicated in the binding of the bacteria to the gastric mucosa in humans, we have ... We have also demonstrated that around 80% of O-glycans carried blood group A, B or H antigens, suggesting that the variation of ... We have identified that the major component was always a core 2-based glycan carrying two blood group H antigens, whatever was ...
Monoclonal Antibody AP3 Binds Galactomannan Antigens Displayed by the Pathogens Aspergillus flavus, A. fumigatus, and A....
Monoclonal Antibody AP3 Binds Galactomannan Antigens Displayed by the Pathogens Aspergillus flavus, A. fumigatus, and A. ... Monoclonal Antibody AP3 Binds Galactomannan Antigens Displayed by the Pathogens Aspergillus flavus, A. fumigatus, and A. ... Immunofluorescence microscopy revealed that AP3 binds a cell wall antigen, but immunoprecipitation and enzyme-linked ... immunosorbent assays showed that the antigen is also secreted into the culture medium. The inability of AP3 to bind the A. ...
"Characterization of t and b antigen-binding cells for beta-galactosida" by S Swain, F Modabber et al.
Induction of the c-myc protooncogene after antigen binding to hapten-specific B cells - Fingerprint - University of...
Mutational landscape of antibody variable domains reveals a switch modulating the interdomain conformational dynamics and...
... both antigen affinity and thermostability by modulating the interdomain conformational dynamics of the antigen-binding fragment ... how mutations at all positions of the variable domains of a high-affinity anti-VEGF antibody G6.31 impact its antigen-binding ... We determine the role of one antigen-distal light chain position 83, demonstrating that mutation at this site optimizes ... both antigen affinity and thermostability by modulating the interdomain conformational dynamics of the antigen-binding fragment ...
An Experimental Study Comparing the Expansion of Peripheral Blood Natural Killer (NK) Cells Cultured with Artificial Antigen...
2012). Membrane-bound IL-21 promotes sustained ex vivo proliferation of human natural killer cells. PLoS ONE,7, e30264. ... NK expansion and activation were stimulated by culture with artificial antigen-presenting cells (aAPCs) and IL-2, in the ... An Experimental Study Comparing the Expansion of Peripheral Blood Natural Killer (NK) Cells Cultured with Artificial Antigen- ... 2014). Donor-derived natural killer cells infused after human leukocyte antigen-haploidentical hematopoietic cell ...
T-cell epitopes are peptides derived from antigens and identified by the T-cell receptor (TCR) when bound to MHC molecules...
B-cell epitopes are solvent-exposed portions of the antigen that bind to secreted and cell-bound immunoglobulins. (a) B-cell ... that enables the acknowledgement of antigens when they are displayed on the surface of antigen-presenting cells (APCs) bound to ... Antigen acknowledgement by B- and T-cells differ greatly. B-cells recognize solvent-exposed antigens through antigen receptors ... T-cell epitopes are peptides derived from antigens and identified by the T-cell receptor (TCR) when bound to MHC molecules ...
Sag MGI Mouse Gene Detail - MGI:98227 - S-antigen, retina and pineal gland (arrestin)
carbohydrate derivative binding. cytoskeletal protein binding. DNA binding. enzyme regulator. hydrolase. ligase ...
The binding profile of SARS-CoV-2 with human leukocyte antigen polymorphisms reveals critical alleles involved in immune...
The binding affinity of human leukocyte antigen (HLA) polymorphisms to SARS-CoV-2 might be related to immune escape, but the ... The binding profile of SARS-CoV-2 with human leukocyte antigen polymorphisms reveals critical alleles involved in immune ... The binding profile of SARS-CoV-2 with human leukocyte antigen polymorphisms reveals criti ... In this study, we obtained the binding affinity of SARS-CoV-2 strains with different HLA proteins and identified 31 risk ...
Binding of HIV-1 gp120 to an anti-V3 loop antibody reveals novel antigen-induced epitopes<...
Binding to the epitopes was shown to require the complexation of Fab with its antigen. The degree of this antigen requirement ... Binding to the epitopes was shown to require the complexation of Fab with its antigen. The degree of this antigen requirement ... Binding to the epitopes was shown to require the complexation of Fab with its antigen. The degree of this antigen requirement ... Binding to the epitopes was shown to require the complexation of Fab with its antigen. The degree of this antigen requirement ...
Frontiers | Reaction of Human Monoclonal Antibodies to SARS-CoV-2 Proteins With Tissue Antigens: Implications for Autoimmune...
... to 55 different tissue antigens. We found that SARS-CoV-2 antibodies had reactions with 28 out of 55 tissue antigens, ... to 55 different tissue antigens. We found that SARS-CoV-2 antibodies had reactions with 28 out of 55 tissue antigens, ... This extensive immune cross-reactivity between SARS-CoV-2 antibodies and different antigen groups may play a role in the multi- ... This extensive immune cross-reactivity between SARS-CoV-2 antibodies and different antigen groups may play a role in the multi- ...
NHANES 2003-2004: Hepatitis B: Core Antibody & Surface Antigen; Hepatitis C: Confirmed Antibody & RNA (HCV-RNA);...
If present, anti-HBs bind to the solid-phase antigen. After washing to remove unbound material, biotin-tagged HBsAg (B-HBsAg) ... Hepatitis B surface antigen. English Text: Hepatitis B surface antigen. Target: Both males and females 6 YEARS - 150 YEARS. ... Participant results are coded positive for surface antigen if the surface antigen test is positive; they are coded negative for ... are incubated with the beads to form antigen-antibody-antigen "sandwich" complexes. The presence of these complexes is ...
CDC - Malaria - Glossary
... "antigens"). The antibodies specifically bind to the antigens that induced the immune response. Antibodies help defend the body ... Antigen: Any substance that stimulates the immune system to produce antibodies. Antigens are often foreign substances such as ... or that are positive in immunologic tests to detect sporozoite antigens. ...
A snapshot of 2021's highlights | Institut Pasteur
A publication has described the Crimean-Congo hemorrhagic fever virus antibody, and in particular the antigen-binding fragment ... Description of the structure of the antigen-binding fragments of Crimean-Congo hemorrhagic fever virus antibodies. ... In a conjugate vaccine prototype, a synthetic sugar component mimics the bacterial antigen which induces antibodies. The ...
Heterogeneous expression of human antibody λ chains by concanavalin A- resistant hybridomas lead to changed antigen binding -...
Protein kinase RNA/FADD/caspase-8 pathway mediates the proapoptotic activity of the RNA-binding protein human antigen R (HuR)<...
The RNA-binding protein human antigen R (HuR) has been implicated in apoptosis in multiple ways. Several studies have shown ... N2 - The RNA-binding protein human antigen R (HuR) has been implicated in apoptosis in multiple ways. Several studies have ... AB - The RNA-binding protein human antigen R (HuR) has been implicated in apoptosis in multiple ways. Several studies have ... abstract = "The RNA-binding protein human antigen R (HuR) has been implicated in apoptosis in multiple ways. Several studies ...
Enzyme-labeled Antigen Method: Factors Influencing the Deterioration of Antigen-binding Activity of Specific Antibodies during...
T1 - Enzyme-labeled Antigen Method. T2 - Factors Influencing the Deterioration of Antigen-binding Activity of Specific ... Enzyme-labeled Antigen Method: Factors Influencing the Deterioration of Antigen-binding Activity of Specific Antibodies during ... Enzyme-labeled Antigen Method: Factors Influencing the Deterioration of Antigen-binding Activity of Specific Antibodies during ... Enzyme-labeled Antigen Method: Factors Influencing the Deterioration of Antigen-binding Activity of Specific Antibodies during ...
A peptide binding protein having a role in antigen presentation is a member of the HSP70 heat shock family. | Journal of...
The T cell recognition of globular protein antigens requires the processing and presentation of the antigen by Ia-expressing ... A peptide binding protein having a role in antigen presentation is a member of the HSP70 heat shock family. A Vanbuskirk, A ... A Vanbuskirk, B L Crump, E Margoliash, S K Pierce; A peptide binding protein having a role in antigen presentation is a member ... We previously described a peptide binding protein of 72/74 x 10(3) Mr (PBP72/74) that plays a role in antigen presentation as ...
T-cell intracellular antigen-1 (TIA1) is an RNA-binding proteins involved with many - MDM2 Protein-mediated Ubiquitination of...
T-cell intracellular antigen-1 (TIA1) is an RNA-binding proteins involved with many. T-cell intracellular antigen-1 (TIA1) is ... We found that immobilized mCRP bound to recombinant soluble integrin v3 in ELISA-type binding assays, but pCRP was much less ... effective in binding of to v3 (Figure 2a) * In contrast, stigmatellin had no effect on NO-dependent portion of leptin-induced ... an RNA-binding proteins involved with many regulatory areas of mRNA fat burning capacity. mRNAs including and ((and advanced ...
HBV-specific CD8 cells show altered MHC/peptide binding in the presence of high levels of circulating viral antigen. - CAMS...
A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary...
T1 - A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary ... title = "A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary ... A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary ... A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary ...
Lymphocyte adhesion through very late antigen 4: evidence for a novel binding site in the alternatively spliced domain of...
R H Vonderheide, T A Springer; Lymphocyte adhesion through very late antigen 4: evidence for a novel binding site in the ... Lymphocyte adhesion through very late antigen 4: evidence for a novel binding site in the alternatively spliced domain of ... The heat-stable antigen can alter very late antigen 4-mediated adhesion. ... completely blocked binding to VCAM-6D but only partially inhibited binding to VCAM-7D. We conclude that there is one VLA-4 ...
Hepatitis B surface antigen binds to human serum albumin cross‐linked by transglutaminase<...
Hepatitis B surface antigen binds to human serum albumin cross‐linked by transglutaminase. / Thung, Swan N.; Wang, De‐Fa ‐F; ... Hepatitis B surface antigen binds to human serum albumin cross‐linked by transglutaminase. In: Hepatology. 1989 ; Vol. 9, No. 5 ... Hepatitis B surface antigen binds to human serum albumin cross‐linked by transglutaminase. Hepatology. 1989 May;9(5):726-730. ... F., Fasy, T. M., Hood, A., & Gerber, M. A. (1989). Hepatitis B surface antigen binds to human serum albumin cross‐linked by ...
The lymphocyte function-associated antigen 1 I domain is a transient binding module for intercellular adhesion molecule (ICAM)...
I-GPI cells bound soluble ICAM-1 (sICAM-1) with a low avidity and affinity. Flow cell experiments demonstrated a specific ... This suggests that the I domain acts as a transient, Mg2+-dependent binding module that cooperates with another Mn2+-stimulated ... 1 and ICAM-3 binding site, but the relationship of this site to regulated adhesion is unknown. To study the adhesive properties ... The I domain of lymphocyte function-associated antigen (LFA)-1 contains an intercellular adhesion molecule (ICAM)- ...
Measurement of Antibody Binding Affinity on Bacterial Surfaces Using Flow Cytometry | Lund University Publications
Determining the affinity of an antibody binding to its antigen is the first step in predicting the function in a physiological ... It is informative to also be able to assess antibody binding to a bacterial surface where many antigens might be present, ... Determining the affinity of an antibody binding to its antigen is the first step in predicting the function in a physiological ... It is informative to also be able to assess antibody binding to a bacterial surface where many antigens might be present, ...
Gynecologic Tumor Markers: Tumor Marker Overview, Cancer Antigen 125, Beta Human Chorionic Gonadotropin
Carbohydrate antigen 19-9. Serum carbohydrate antigen 19-9 is elevated in up to 35% of patients with endometrial cancer and can ... Cancer antigen 27-29. Elevated cancer antigen 27-29 levels are associated with cancers of the colon, stomach, kidney, lung, ... Squamous cell carcinoma antigen. Squamous cell carcinoma (SCC) antigen may be increased in patients with epidermoid carcinoma ... SCC antigen is useful in the clinical management of advanced cervical cancer. Beta-hCG and alpha-fetoprotein have proved to be ...
1E27: Nonstandard peptide binding of HLA-B*5101 complexed with HIV immunodominant epitope KM1(LPPVVAKEI)