Aziridines are organic compounds containing the aziridine functional group, a three-membered heterocycle with one amine (-NR-) ... Alkene + DPH → R h 2 ( C O 2 R ) 4 {\displaystyle {\xrightarrow {Rh_{2}(CO_{2}R)_{4}}}} Aziridine For instance, Ph-Aziridine-Me ... The De Kimpe aziridine synthesis allows for the generation of aziridines by reacting an α-chloroimine with a nucleophile, such ... which affords aziridines. Aziridines are obtained by treating a mono-, di-, tri- or tetra- substituted alkene (olefin) with O-( ...
Aziridine containing compounds also appear to be similarly dangerous. Binary ethylenimine, a dimeric form of aziridine " ... Its derivatives, also referred to as aziridines, are of broader interest in medicinal chemistry. The bond angles in aziridine ... Aziridine is highly toxic with an LD50 of 14 mg (oral, rats). It is a skin irritant. As an alkylating agent, it is also a ... Aziridine is less basic than acyclic aliphatic amines, with a pKa of 7.9 for the conjugate acid, due to increased s character ...
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Adducts derived from P(NMe2)3 and α-ketoesters are effectively intercepted by N-sulfonyl imines, affording a range of aziridine ... A mild, convenient protocol for the synthesis of cis-aziridines employs a catalytic amount of Br nsted acid. Diazo compound ... The tertiary amine DABCO catalyzes the reaction of imines with phenacyl bromide derivatives to afford functionalized aziridines ... PF6 to produce the corresponding aryl aziridine carboxylates in high yields with excellent cis-diastereoselectivity.. J. S. ...
... derived chiral guanidine was developed as an efficient Brønsted base catalyst for the desymmetrization of meso-aziridines with ... Guanidine-catalyzed enantioselective desymmetrization of meso-aziridines† Yan Zhang,a Choon Wee Kee,a Richmond Lee,b Xiao Fu,a ... catalyzed enantioselective desymmetrization of meso-aziridines Y. Zhang, C. W. Kee, R. Lee, X. Fu, J. Y. Soh, E. M. F. Loh, K. ... for the desymmetrization of meso-aziridines with both thiols. and carbamodithioic acids as nucleophiles, which provided 1,2- ...
... Satoshi Minakata, Yuriko Okada, Yoji Oderaotoshi ...
The reaction of 2-naphthols with aziridines in the presence of AgOTf resulting in a dehydrative, formal [3+2] annulation is ... A preliminary study on the mechanism of this reaction indicates an SN1-type ring-opening of aziridines. This method is ... AgOTf-catalyzed dehydrative [3+2] annulation of aziridines with 2-naphthols T. Kaicharla, A. Jacob, R. G. Gonnade and A. T. ... The reaction of 2-naphthols with aziridines in the presence of AgOTf resulting in a dehydrative, formal [3+2] annulation is ...
Two alternative and complementary one-pot procedures for the direct transformation of 2-amino alcohols to N-tosyl aziridines ... Short and Efficient Synthesis of Optically Active N-Tosyl Aziridines from 2-Amino Alcohols. Lothar W. Bieber * and Maria C. F. ... Bieber, L.W.; De Araújo, M.C.F. Short and Efficient Synthesis of Optically Active N-Tosyl Aziridines from 2-Amino Alcohols. ... Two alternative and complementary one-pot procedures for the direct transformation of 2-amino alcohols to N-tosyl aziridines ...
A novel and selective fluoride opening of aziridines by XtalFluor-E. synthesis of fluorinated diamino acid derivatives.. [ ... The method based on the selective aziridine opening by fluoride has been generalized to afford access to mono- or bicyclic ... or cyclohexane carboxylate has been developed through a novel and efficient fluoride opening of an activated aziridine ring ... proceeded through a stereoselective aziridination of the olefinic bond of a bicyclic lactam and regioselective aziridine ring ...
Cyclophellitol epoxides and aziridines are recently established covalent glycosidase inactivators. Inspired by the application ... in complex with beta Cyclophellitol Aziridine probe KY358. *DOI: 10.2210/pdb5NPE/pdb ...
Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus, which displays high in vitro activity against Gram- ... Ficellomycin is an aziridine antibiotic produced by Streptomyces ficellus, which displays high in vitro activity against Gram- ... Ittah Y, Sasson Y, Shahak I, Tsaroom S, Blum J (1978) A new Aziridine synthesis from 2-azido alcohols and tertiary phosphines. ... Ismail F, Levitsky D, Dembitsky V (2009) Aziridine alkaloids as potential therapeutic agents. Eur J Med Chem 44(9):3373-3387 ...
... aziridine-2-carboxylic acid , C7H9NO4-2 , CID 3460800 - structure, chemical names, physical and chemical properties, ...
The C-4 carbonyl oxygen of the quinazolinone (Q*) was found to participate in the aziridine ring-opening under some conditions ... Finally, the sense of regioselectivity in the ring-opening of the methyl acrylate-derived aziridine can be changed by forming a ... Thus Q* as a substituent on nitrogen was found to be sufficiently electron-withdrawing to activate the aziridine ring towards ... The two N-invertomers of the indene-derived aziridine were separately ring-opened by hydrogen chloride with very different ...
160-5000 and a cationic polymerization retarding agent(s). A two-component cationically-curable aziridine polyether-based ... and an aziridine salt(s) of an acid, and a base component including a mixture of N-alkylaziridine polyol ethers with imino ... composition comprises: (1) a catalyst component comprising: (a) 0.01-50 wt.% acid(s); (b) 0.01-99.5 wt.% aziridine salt(s) of ... A two-component cationically-curable aziridine polyether-based composition comprises a catalyst component, including an acid(s ...
... ... Occupational asthma and contact dermatitis in a spray painter after introduction of an aziridine cross-linker. Environmental ... dermatitis and respiratory difficulty characterized by small airways obstruction shortly after the polyfunctional aziridine ...
Mechanistic Approaches to Asymmetric Synthesis of Aziridines from Guanidinium Ylides and Aryl Aldehydes (共著) Tetrahedron ...
"Oligomers of aziridines and N-beta-aziridinoethylamides" Bull. of the Acad. of Sci. of USSR 37(11 part2): 2315-2323 (1988)... ... The method according to claim 1, wherein the moiety is an aziridine.. 17. The method according to claim 1, wherein the blood ... The method according to claim 21, wherein the moiety is an aziridine.. 37. The method according to claim 21, wherein the blood ... The method according to claim 41, wherein the moiety is an aziridine.. 56. The method according to claim 41, wherein the blood ...
where to buy 71243-81-7(Hexanedioic acid, polymer with N-(2-aminoethyl)-1,2-ethanediamine and aziridine, reaction products with ... 2-ethanediamine and aziridine, reaction products with epichlorohydrin and polyethylene glycol) including MSDS sheet(poisoning, ... 2-ethanediamine and aziridine, reaction products with epichlorohydrin and polyethylene glycol) for price inquiry. ... Hexanedioic acid, polymer with N-(2-aminoethyl)-1,2-ethanediamine and aziridine, reaction products with epichlorohydrin and ...
Comprehensive supplier list for Aziridine, 1-(1,1-dimethylethoxy)-2,2,3-trimethyl-,Aziridine, 1-(1,1-dimethylethyl)-2,3- ... Aziridine,1-(3-pyridinylcarbonyl)- (9CI); Aziridine, 1-nicotinoyl- (8CI);1-(3-Pyridinecarbonyl)aziridine Molecular Formula: C8H ... AZIRIDINE, 1-(1-PROPENYL)-, (E)- (6 suppliers). IUPAC Name: 1-[(E)-prop-1-enyl]aziridine , CAS Registry Number: 80839-91-4. ... AZIRIDINE, 1-(1-CYCLOHEXEN-1-YL)- (7 suppliers). IUPAC Name: 1-(cyclohexen-1-yl)aziridine , CAS Registry Number: 153616-85-4. ...
However, ring opening was found to be only feasible for the epoxide and the activated aziridine, and not for the nonactivated ... However, ring opening was found to be only feasible for the epoxide and the activated aziridine, and not for the nonactivated ... CHIRAL AZIRIDINES, FREE-ENERGY. journal title JOURNAL OF ORGANIC CHEMISTRY. J. Org. Chem.. volume. 76. issue. 21. pages. 8698 ... 2011). Reactivity of activated versus nonactivated 2-(bromomethyl)aziridines with respect to sodium methoxide: a combined ...
Vervisch K, Dhooghe M, Törnroos K, De Kimpe N. Synthesis of stereodefined piperidines from aziridines and their transformation ... Vervisch, K., Dhooghe, M., Törnroos, K., & De Kimpe, N. (2010). Synthesis of stereodefined piperidines from aziridines and ... AZIRIDINES. journal title JOURNAL OF ORGANIC CHEMISTRY. J. Org. Chem.. volume. 75. issue. 22. pages. 7734 - 7744. Web of ... Synthesis of stereodefined piperidines from aziridines and their transformation into conformationally constrained amino acids, ...
a Asymmetric synthesis of α,β-diamino acid derivatives with an aziridine-, azetidine- and γ-lactone-skeleton via Mannich-type ... Asymmetric synthesis of α,β-diamino acid derivatives with an aziridine-, azetidine- and γ-lactone-skeleton via Mannich-type ... Asymmetric synthesis of α,β-diamino acid derivatives with an aziridine-, azetidine- and γ-lactone-skeleton via Mannich-type ... "Asymmetric Synthesis of Α,β-diamino Acid Derivatives with an Aziridine-, Azetidine- and Γ-lactone-skeleton via Mannich-type ...
... aziridine) Ligands. Together they form a unique fingerprint. * aziridine Chemical Compounds ... Enantioselective Addition of Organolithium Reagents to Imines Mediated by C2-Symmetric Bis(aziridine) Ligands. In: Tetrahedron ... Enantioselective Addition of Organolithium Reagents to Imines Mediated by C2-Symmetric Bis(aziridine) Ligands. / Johansson, F. ... Enantioselective Addition of Organolithium Reagents to Imines Mediated by C2-Symmetric Bis(aziridine) Ligands. Tetrahedron. ...
This project presents the progress towards regioselective nucleophilic ring openings on aziridines using p-methoxy phenol in ... This project presents the progress towards regioselective nucleophilic ring openings on aziridines using p-methoxy phenol in ... This project presents the progress towards regioselective nucleophilic ring openings on aziridines using p-methoxy phenol in ...
This search was done on November 16, 2018. It was compiled from government data last released on April 30, 2018. The data were obtained from the U.S. EPAs Risk Management System database (RMP).. ...
Based on the three-dimensional structure of HLA-B27, we have synthesized a ligand with an aziridine-containing side chain ... Using tryptic digestion followed by mass spectrometry and amino acid sequencing, the aziridine-containing ligand is shown to ... Based on the three-dimensional structure of HLA-B27, we have synthesized a ligand with an aziridine-containing side chain ... Using tryptic digestion followed by mass spectrometry and amino acid sequencing, the aziridine-containing ligand is shown to ...
Zhou, J., Yeung, Y.-Y. (2014-04-18). N -bromosuccinimide-induced aminocyclization-aziridine ring-expansion cascade: An ... A novel N-bromosuccinimide induced aminocyclization-aziridine ring expansion cascade is reported. Substituted azepanes were ... N -bromosuccinimide-induced aminocyclization-aziridine ring-expansion cascade: An asymmetric and highly stereoselective ...
... ... Also covered, is manufacturers data on listed Global and China Aziridine Market production capacity, market share, production ... The influence of Aziridine industry policy is discussed in this research along with product specifications, manufacturing ... Statistics of global and Chinas key Aziridine manufacturers with their capacity of production, cost, price, profit, production ...