Vitamin C and azacitidine restore the 5hmC landscape and phenotypes in TET2-mutant HSPCs. These findings offer a comprehensive ...
"My hope is that the combination of APR-246 with azacitidine in MDS patients with TP53 mutation will be a promising therapeutic ...
Thrice weekly azacitidine does not improve hematological responses in lower-risk myelodysplastic syndromes: a study of the ...
A Phase 1 Study of Romidepsin, CC-486 (5-azacitidine), dexamethasone, and lenalidomide (RAdR) for relapsed/refractory T-cell ...
Soon after, he had a relapsing molecular disease which was refractory to chemotherapy including FLA-Ida and azacitidine. He had ...
Venetoclax with azacitidine or decitabine in patients with newly diagnosed acute myeloid leukemia: Long term follow-up from a ... Pracinostat plus azacitidine in older patients with newly diagnosed acute myeloid leukemia: results of a phase 2 study ... Pevonedistat with azacitidine in older patients with TP53-mutated AML: a phase 2 study with laboratory correlates. ... Impact of Venetoclax and Azacitidine in Treatment-Naïve Patients with Acute Myeloid Leukemia and IDH1/2 Mutations. ...
19-606: A phase 1b/2 study of IMGN632 as monotherapy or combination with venetoclax and/or azacitidine for patients with CD123- ...
... azacitidine) had significantly increased overall survival compared to those treated with conventional care regimens (CCR). ...
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BeiGene markets ABRAXANE® (nanoparticle albumin-bound paclitaxel), REVLIMID® (lenalidomide), and VIDAZA® (azacitidine) in China ...
Double epigenetic modulation of high-dose chemotherapy with azacitidine and vorinostat for patients with refractory or poor- ... Double epigenetic modulation of high-dose chemotherapy with azacitidine and vorinostat for patients with refractory or poor- ...
... in Integrative genomics identifies the molecular basis of resistance to Azacitidine therapy in Myelodysplastic Syndromes, ... 2017, Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes, ... 2016, Integrative genomics identifies the molecular basis of resistance to Azacitidine therapy in Myelodysplastic Syndromes, ...
... eccrine hidradenitis resembling acanthosis nigricans in a patient with acute myeloid leukemia associated with azacitidine and ...
Phase II Trial Studying the Efficacy of Lenzilumab or High Dose Ascorbate plus Azacitidine Based on Molecular Profiling ...
This includes AML patients on a clinical trial of azacitidine +/- venetoclax (NCT02993523), patients with 17p deletion CLL on ...
Azacitidine was administered on Days 1-7 every cycle at 75 mg/m 2 /day intravenously/subcutaneously. Responses were assessed ... Venetoclax + azacitidine shows activity in patients with R/R MDS following prior HMA therapy failure and provides clinically ... Herein, we present the safety and efficacy of venetoclax + azacitidine in patients with R/R MDS. This phase 1b, open-label, ... A phase 1b study of venetoclax and azacitidine combination in patients with relapsed or refractory myelodysplastic syndromes. [ ...
Influence of mild bone marrow fibrosis on response of int-2/high risk MDS patients to 5-azacitidine. Leuk Res. 2011; 35:S126- ...
azacitidine for treatment related myelodysplastic syndrome/acute myeloid leukaemia (widening access). Breast and blood cancer ...
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic ... Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic ... Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic ... Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic ...
... iadademstat has shown encouraging safety and efficacy data in combination with azacitidine (see Salamero et al., ASH 2022 oral ...
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Azacitidine in the Front-line Treatment of Therapy-related Myeloid Neoplasms: A Multicenter Case Series (free) ...
Stability of Azacitidine Solutions In Sterile Water For Injection. Tyono I, Law S, Charbonneau L, Walker S.E. Poster presented ... Did our fabrication process impact on azacitidine stability ? Khan A, Bernadou JM, Xyereb F, Berroneau A, Crauste-Manciet S. ...
... beginning with venetoclax/azacitidine and standard induction cytarabine/daunorubicin chemotherapy in NPM1-mutant and KMT2A- ...
... and to progression to AML in the course of azacitidine treatment [10]. To our knowledge, no studies have been yet conducted ...
... discusses an early study that looked at a combination of the immunotherapy magrolimab with the chemotherapy azacitidine (Vidaza ...
Gilead also nixed assessing the drug with or without azacitidine for patients with higher-risk myelodysplastic syndromes in the ...
Wang W, Wang J, Chen M, Liang Y, LI Z, Zhang Z and Jing H: 5-Azacitidine remolds the methylation status and inhibits growth in ...