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*  Alopecia Areata - Are We Nearing A Cure? | HIS Hair Clinic
... the follicles begin to emit autoantigens, the cell's alarm bells, and are destroyed. Latest Research. Ralf Paus is a ...
https://www.hishairclinic.com/alopecia-areata-are-we-nearing-a-cure/
*  T and Tn, general carcinoma autoantigens | Science
Primary and metastatic carcinomas are epithelial in origin and comprise by far the largest group of malignant tumors in humans. In most of these tumors, T and Tn antigens, whose epitopes have been synthesized, are uncovered and immunoreactive. In all other tissues T and Tn antigens are masked and not accessible to the immune system; they are generally precursors in normal complex carbohydrate chains. Thus, carcinomas have antigens recognized as foreign by the patients' immune system. The expression of T and Tn antigens has pathogenic and clinical consequences, and the antigens themselves are powerful histological markers in carcinoma diagnosis and frequently in prognosis. Most patients distinguish their carcinoma from all other cells, as shown by strong autoimmune responses to T antigen. These responses are readily measured by assays, and they allow detection of carcinomas with greater sensitivity and specificity frequently earlier than previously possible. Moreover, the extent of T and Tn ...
http://science.sciencemag.org/content/224/4654/1198
*  Autoantibodies and autoantigens in autoimmune hepatitis.
Autoantibodies and their corresponding autoantigens are intensively studied to provide clues to the understanding of disease ...
https://www.omicsonline.org/references/autoantibodies-and-autoantigens-in-autoimmune-hepatitis-708944.html
*  Detection and Analysis of Autoantigens Targeted by Autoantibodies in Immunorelated Pancytopenia
... Hui Liu, Rong Fu, Yihao Wang, ... Vinitha Ganesan, Dana P. Ascherman, and Jonathan S. Minden, "Immunoproteomics technologies in the discovery of autoantigens in ...
https://www.hindawi.com/journals/jir/2013/297678/citations/
*  Autoantigen discovery with a synthetic human peptidome. - PubMed - NCBI
Autoantigen discovery with a synthetic human peptidome.. Larman HB1, Zhao Z, Laserson U, Li MZ, Ciccia A, Gakidis MA, Church GM ... However, current approaches to characterize autoantigens have, in most cases, met only with limited success. Here we present a ... Immune responses targeting self-proteins (autoantigens) can lead to a variety of autoimmune diseases. Identification of these ... Application of a synthetic human proteome to autoantigen discovery through PhIP-Seq ...
https://www.ncbi.nlm.nih.gov/pubmed/21602805
*  Immunomodulation of RA Patients' PBMC with a Multiepitope Peptide Derived from Citrullinated Autoantigens
... Smadar Gertel,1,2 ... PBMC with a Multiepitope Peptide Derived from Citrullinated Autoantigens," Mediators of Inflammation, vol. 2017, Article ID ...
https://www.hindawi.com/journals/mi/2017/3916519/cta/
*  Myelin oligodendrocyte glycoprotein: a novel candidate autoantigen in multiple sclerosis | SpringerLink
... indicating that this specific CNS autoantigen, or some of its determinants, can induce a pathogenic response across animal ... clearly indicates that MOG is probably an important target autoantigen in this disease. ... Myelin oligodendrocyte glycoprotein Multiple sclerosis Experimental autoimmune encephalomyelitis Demyelination Autoantigen ...
https://link.springer.com/article/10.1007%2Fs001090050092
*  Autoantigens in primary biliary cirrhosis | Journal of Clinical Pathology
The M2 mitochondrial autoantigens. NATURE OF THE ANTIGEN(S). It has been appreciated since the 1960s that most patients with ... Identification and analysis of the major M2 autoantigens in primary biliary cirrhosis. Proc Natl Acad Sci U S A 1988;85:8654-8. ... M4 and M9 autoantigens in primary biliary cirrhosis-a negative study. J Hepatol 1993;18:252-4. ... Evans J, Rueben A, Craft C. PBC95K, a 95 kilodalton nuclear autoantigen in primary biliary cirrhosis. Arthritis Rheum 1991;34: ...
http://jcp.bmj.com/content/53/11/813
*  JCI - Two rheumatoid arthritis-specific autoantigens correlate microbial immunity with autoimmune responses in joints
A novel human autoantigen, endothelial cell growth factor, is a target of T and B cell responses in patients with Lyme disease ... copri, the greater the autoantibody responses against these autoantigens.. Figure 3. Autoantibody correlations with P. copri ... Both autoantigens are highly expressed in inflamed synovial tissue; they share homologous T cell epitopes with Prevotella and ... A highly expressed human protein, apolipoprotein B-100, serves as an autoantigen in a subgroup of patients with Lyme disease. J ...
https://jci.org/articles/view/93450
*  JCI - Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance
Autoimmune responses to meiotic germ cell antigens (MGCA) that are expressed on sperm and testis occur in human infertility and after vasectomy. Many MGCA are also expressed as cancer/testis antigens (CTA) in human cancers, but the tolerance status of MGCA has not been investigated. MGCA are considered to be uniformly immunogenic and nontolerogenic, and the prevailing view posits that MGCA are sequestered behind the Sertoli cell barrier in seminiferous tubules. Here, we have shown that only some murine MGCA are sequestered. Nonsequestered MCGA (NS-MGCA) egressed from normal tubules, as evidenced by their ability to interact with systemically injected antibodies and form localized immune complexes outside the Sertoli cell barrier. NS-MGCA derived from cell fragments that were discarded by spermatids during spermiation. They egressed as cargo in residual bodies and maintained Treg-dependent physiological tolerance. In contrast, sequestered MGCA (S-MGCA) were undetectable in residual bodies and ...
https://jci.org/articles/view/89927/figure/5
*  JCI - Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance
Egress of sperm autoantigen from seminiferous tubules maintains systemic tolerance. Kenneth S.K. Tung,1,2,3 Jessica Harakal,2,3 ... It also does not apply to the S-MGCA targeted in EAO after vasectomy (32). The selection of pathogenic autoantigens in a given ... Systemic tolerance is autoantigen dependent and involves multiple mechanisms (5). Tolerance begins in the thymus, controlled ... and autoantigen recognition (13) that occurs in the regional lymph nodes. Each regional lymph node expresses unique TCR ...
https://www.jci.org/articles/view/89927
*  RCSB PDB - Protein Feature View - Nuclear autoantigen Sp-100 - H0Y4R8 (H0Y4R8 HUMAN)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
http://www.rcsb.org/pdb/protein/H0Y4R8
*  "Cytoplasmic Proteins as Autoantigens in the Development of Inflammator" by Bharathi Yalaka
To this end, we made efforts to identify cardiac autoantigens that can potentially become immune targets in the CVB ... Cytoplasmic Proteins as Autoantigens in the Development of Inflammatory Heart Disease. Bharathi Yalaka, University of Nebraska ... To this end, we made efforts to identify cardiac autoantigens that can potentially become immune targets in the CVB ... Yalaka, Bharathi, "Cytoplasmic Proteins as Autoantigens in the Development of Inflammatory Heart Disease" (2017). ETD ...
http://digitalcommons.unl.edu/dissertations/AAI10690859/
*  Emerging roles for the Ro 60-kDa autoantigen in noncoding RNA metabolism. - PubMed - NCBI
Emerging roles for the Ro 60-kDa autoantigen in noncoding RNA metabolism.. Sim S1, Wolin SL. ... Emerging roles for the Ro 60 kDa autoantigen in noncoding RNA metabolism ... Emerging roles for the Ro 60 kDa autoantigen in noncoding RNA metabolism ... Emerging roles for the Ro 60 kDa autoantigen in noncoding RNA metabolism ...
https://www.ncbi.nlm.nih.gov/pubmed?term=21823229
*  WikiGenes - ICA1L - islet cell autoantigen 1,69kDa-like
The world's first wiki where authorship really matters. Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts.
https://www.wikigenes.org/e/gene/e/130026.html
*  Carbamylated vimentin represents a relevant autoantigen in Latin American (Cuban) rheumatoid arthritis patients | SpringerLink
Pathogenic models of RA nowadays include smoking as a relevant trigger factor of immune reactions to autoantigens modified by ... Bang H, Egerer K, Gauliard A (2007) Mutation and citrullination modifies vimentin to a novel autoantigen for rheumatoid ... As an ubiquitous expressed auto-antigen, vimentin might be of special relevance in triggering ACPA production. Vimentin ... Although reactivity against modified vimentin was predominant, the modified peptides were also recognized as autoantigens by ...
https://link.springer.com/article/10.1007%2Fs00296-016-3472-9
*  Epidermal Transglutaminase (TGase 3) Is the Autoantigen of Dermatitis Herpetiformis | JEM
Epidermal Transglutaminase (TGase 3) Is the Autoantigen of Dermatitis Herpetiformis. Miklós Sárdy, Sarolta Kárpáti, Barbara ... Recently, tissue transglutaminase (TGc, EC 2.3.2.13) was shown to be the predominant autoantigen in these sections (3, 4) and ... By comparing the Ab responses to skin transglutaminases we could show that CD and DH are diseases where the main autoantigens ... The discovery of TGc as the main endomysial autoantigen failed to explain why only a proportion of gluten sensitive patients ...
http://jem.rupress.org/content/195/6/747
*  Epidermal Transglutaminase (TGase 3) Is the Autoantigen of Dermatitis Herpetiformis | JEM
Epidermal Transglutaminase (TGase 3) Is the Autoantigen of Dermatitis Herpetiformis. Miklós Sárdy, Sarolta Kárpáti, Barbara ... Epidermal Transglutaminase (TGase 3) Is the Autoantigen of Dermatitis Herpetiformis. Miklós Sárdy, Sarolta Kárpáti, Barbara ...
http://jem.rupress.org/content/195/6/747/tab-figures-data
*  Thyroid autoantigen | definition of Thyroid autoantigen by Medical dictionary
What is Thyroid autoantigen? Meaning of Thyroid autoantigen medical term. What does Thyroid autoantigen mean? ... Looking for online definition of Thyroid autoantigen in the Medical Dictionary? Thyroid autoantigen explanation free. ... redirected from Thyroid autoantigen) FLNB. A gene on chromosome 3p14.3 that encodes filamin B, an actin-binding protein which ... Thyroid autoantigen , definition of Thyroid autoantigen by Medical dictionary https://medical-dictionary.thefreedictionary.com/ ...
https://medical-dictionary.thefreedictionary.com/Thyroid+autoantigen
*  Sssca1 - Sjoegren syndrome/scleroderma autoantigen 1 homolog - Mus musculus (Mouse) - Sssca1 gene & protein
Sjoegren syndrome/scleroderma autoantigen 1 homologAdd BLAST. 198. Amino acid modifications. Feature key. Position(s). ... sp,P56873,SSA27_MOUSE Sjoegren syndrome/scleroderma autoantigen 1 homolog OS=Mus musculus GN=Sssca1 PE=1 SV=1 ...
http://www.uniprot.org/uniprot/P56873
*  New hepatic autoantigens in mice with APS-1 like disease | ECE2008
New hepatic autoantigens in mice with APS-1 like disease. Matthias Hardtke-Wolenski1, Katja Fischer1, Mark Anderson2, Michael P ... With this approach we identified several potential new autoantigens of the humoral immune response. ...
https://www.endocrine-abstracts.org/ea/0016/ea0016p267.htm
*  T cells take aim at a ubiquitous autoantigen in multiple sclerosis | Science Translational Medicine
T cells take aim at a ubiquitous autoantigen in multiple sclerosis Message Subject. (Your Name) has forwarded a page to you ...
http://stm.sciencemag.org/content/10/462/eaau8826.full
*  Islet cell autoantigen 1 / ICA1 antibody | acris-antibodies.com
Alternative names for Islet cell autoantigen 1 / ICA1 antibody. ICA69, ICAp69, 69 kDa islet cell autoantigen, Islet cell ... Background of Islet cell autoantigen 1 / ICA1 antibody. Kit Component:. - KN202149G1, ICA1 gRNA vector 1 in pCas-Guide vector. ...
https://www.acris-antibodies.com/target/islet-cell-autoantigen-1-antibody-ica1-antibody.htm?ab_ag_reactivity=Rt
*  AROTEC Autoantigen Standards
Our human neutrophil purified autoantigens offer the most authentic autoantibody targets. Animal sourced autoantigens also ... Native autoantigens are prepared using proprietary technology that does not expose the end user to patent issues.. Value. ... Our highly active autoantigens can be used at very low concentrations in ELISA, down to 10-100ng/well, offering a cost ... AROTEC produces autoantigen lots from analytical (a few milligrams) to bulk (approaching grams) amounts. Large lot sizes ...
https://www.arodia.com/Resources/Protein_standards.html
*  KAKEN - Research Projects | Molecular cloning of autoantigens in rheumatoid arthritis (KAKENHI-PROJECT-08457152)
We cloned three cDNAs encoding autoantigens in rheumatoid arthritis (RA) by immunological screening of lambda phage synovial ... Publications] Tanaka M., et al.: 'Follistatin-related protein (FRP) as a cloned novel autoantigen in rheumatoid arthritis.' ... Publications] Sobajima J.,et al.: 'Novel autoantigens of pANCA in ulcerative colitis : non-histone chromosomal proteins,HMG1 ... Publications] Tanaka M., 他: 'Follistatin-related protein (FRP) as a cloned novel autoantigen in rheumatoid arthritis.' ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08457152/