Autoimmune ataxic neuropathies (sensory ganglionopathies): are glycolipids the responsible autoantigens?
Researchers interested in Autoantigens | Yale School of Medicine
British Library EThOS: Identification and characterisation of novel melanocyte autoantigens in alopecia areata
Identification and characterisation of novel melanocyte autoantigens in alopecia areata Author: Alhaslok, Alfituri ISNI: 0000 ... Conclusions: Phage-display technology was useful for identifying novel autoantigens in alopecia areata. Further work is ... Methods: Patient recruitment and assessment; phage-display technology to identify melanocyte autoantigens; radioligand binding ... to identify and characterise novel melanocyte autoantigens using phage-display technology in order to aid a detailed ...
JCI - Serological cross-reactivity between a human Ro/SS-A autoantigen (calreticulin) and the lambda Ral-1 antigen of...
We have cloned and sequenced a 46-kD Ro/SS-A autoantigen gene that is the human homologue of the calcium-binding protein, ... Serological cross-reactivity between a human Ro/SS-A autoantigen (calreticulin) and the lambda Ral-1 antigen of Onchocerca ... Serological cross-reactivity between a human Ro/SS-A autoantigen (calreticulin) and the lambda Ral-1 antigen of Onchocerca ... to determine whether antibodies produced by onchocerciasis patients might crossreact with the human 46-kD Ro/SS-A autoantigen ( ...
JCI - Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2...
RA33 is a nuclear autoantigen with an apparent molecular mass of 33 kD. Autoantibodies against RA33 are found in about 30% of ... Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of ... and thus identify on a molecular level a new autoantigen. ...
"Periplakin, an autoantigen in paraneoplastic pemphigus and pemphigus f" by Shideh Kazerounian
Investigation of the epitope specificities of antibodies to islet β-cell autoantigens - Nottingham ePrints
Al-bukhari, Talat Abdullah (2001) Investigation of the epitope specificities of antibodies to islet β-cell autoantigens. PhD ... Investigation of the epitope specificities of antibodies to islet β-cell autoantigens ... Antigenic determinants, Epitope mapping, Type 1 diabetes mellitus, GAD-65, Autoantigens, Monoclonal antibodies. ... antibodies on GAD-65 and IA-2 may help to understand the relationship between antigenicity and structure in these autoantigens ...
KAKEN - Research Projects | Interracial study of pathogenesis in type 1 diabetes by using a novel autoantigen INS-IGF2. ...
Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing...
Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing- ... Autoantigen-specific immunosuppression with tolerogenic peripheral blood cells prevents relapses in a mouse model of relapsing- ... For clinical application such DCs are difficult to generate and autoantigens hold the risk of exacerbating the disease. Methods ... Background: Dendritic cells (DCs) rendered suppressive by treatment with mitomycin C and loaded with the autoantigen myelin ...
A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the...
R Kain, K Matsui, M Exner, S Binder, G Schaffner, E M Sommer, D Kerjaschki; A novel class of autoantigens of anti-neutrophil ... A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the ...
Homologies between proteins of Borrelia burgdorferi and thyroid autoantigens. | Read by QxMD
Direct comparison of T cell receptor avidity of auto-antigen specific conventional and regulatory T cells
A newly generated mouse strain, expressing a TCRb-chain specific for the murine auto-antigen MOG and endogenous TCRa-chain, was ... Direct comparison of T cell receptor avidity of auto-antigen specific conventional and regulatory T cells. ... Direct comparison of T cell receptor avidity of auto-antigen specific conventional and regulatory T cells. en. ... Direkter Vergleich von T-Zell-Rezeptor Avidität der Auto-Antigen-spezifischen konventionellen und regulatorischen T-Zellen. de ...
The auto-antigen repertoire in myasthenia gravis<...
The auto-antigen repertoire in myasthenia gravis. Kathleen Vrolix, Judith Fraussen, Peter C. Molenaar, Mario Losen, Veerle ... The auto-antigen repertoire in myasthenia gravis. / Vrolix, Kathleen; Fraussen, Judith; Molenaar, Peter C. et al. In: ... Vrolix, K, Fraussen, J, Molenaar, PC, Losen, M, Somers, V, Stinissen, P, De Baets, MH & Martinez-Martinez, P 2010, The auto- ... The auto-antigen repertoire in myasthenia gravis. In: Autoimmunity. 2010 ; Vol. 43, No. 5-6. pp. 380-400. ...
Sjogren's syndrome - Study of autoantigens and autoantibodies
Sjogrens syndrome - Study of autoantigens and autoantibodies. Routsias, JG; Tzioufas, AG URI: http://hdl.handle.net/123456789/ ...
Antigen: What It Is, Function, Types, & Testing
Autoantigens. Autoantigens are markers on cells inside your body that your immune system attacks even though they shouldnt. ... Autoantigens cause autoimmune diseases.. Tumor antigens. Tumor antigens are markers on the surface of tumors. You might hear ... These include exogenous antigens, endogenous antigens, autoantigens and tumor antigens.. Exogenous antigens. Exogenous antigens ...
Serval - Limited heterogeneity of autoantigens and T cells in autoimmune diseases?
Contrary to induced autoimmune diseases, little is known about the autoantigens recognized by these autoimmune T cells and the ... The aim of this work was to establish a system which allows characterization of relevant autoantigens in spontaneous insulin- ...
Ep. 13: 'Pathogens, Autoantigens, and Antigens' Featuring Dr. Frances Lund - The Immunology Podcast
Receptor-Like Protein Tyrosine Phosphatases, Class 8 - Medical Dictionary online-medical-dictionary.org
Evaluation of autoantibody profiles in a cohort of new-onset pediatric systemic lupus erythematosus patients using autoantigen...
SAM identified increased reactivity against more than 50 autoantigens in new-onset pSLE patients compared to controls, with a ... New-onset pSLE patients have a broad spectrum of antibodies directed against many autoantigens, including those not classically ... Evaluation of autoantibody profiles in a cohort of new-onset pediatric systemic lupus erythematosus patients using autoantigen ... Evaluation of autoantibody profiles in a cohort of new-onset pediatric systemic lupus erythematosus patients using autoantigen ...
Non-monooxygenase cytochromes P450 as potential human autoantigens in anticonvulsant hypersensitivity reactions. | Profiles RNS
Antigen - wikidoc
Cloning of a novel nucleolar guanosine 5′-triphosphate binding protein autoantigen from a breast tumor<...
Cloning of a novel nucleolar guanosine 5′-triphosphate binding protein autoantigen from a breast tumor. In: Cell Growth and ... Cloning of a novel nucleolar guanosine 5′-triphosphate binding protein autoantigen from a breast tumor. / Racevskis, Janis; ... Cloning of a novel nucleolar guanosine 5′-triphosphate binding protein autoantigen from a breast tumor. Cell Growth and ... Dive into the research topics of Cloning of a novel nucleolar guanosine 5′-triphosphate binding protein autoantigen from a ...
Bloch Laboratory: Donald Bloch, MD
Mutations in the gene encoding one autoantigen within the PML-Sp100 nuclear body, designated Sp110, were found to cause an ... In addition, members of the laboratory investigate the structure and function of human autoantigens, with the intention of ... Identification and Characterization of Novel, Primary Biliary Cirrhosis-related, Human Autoantigens. Our studies used the ...
Self-protein - Wikipedia
Autoantigens and autoimmunity: a bedside to bench and back again story | NIH Office of Intramural Research
Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation
Initial studies suggest that CLL mAbs bind autoantigens. Since apoptosis can make autoantigens accessible for recognition by ... Particular IGHV and IGHV/D/J rearrangements contributed to autoantigen binding, although the presence and degree of reactivity ... Thus, clonal expansion in CLL may be stimulated by autoantigens occurring naturally during apoptosis. These data suggest that ... we sought to determine if CLL mAbs recognize autoantigens associated with apoptosis. In general, ~60% of CLL mAbs bound the ...
Do epitopes derived from autoantigens display low affinity for MHC class I? Reply - Oxford Stem Cell Institute
Ex vivo Charakterisierung von humanen Autoantigen-spezifischen CD4+ T-Zellen mit Fokus auf Multiple Sklerose
Autoantigen-spezifische Memory-T-Zellen waren in der Lage, inflammatorische (TNF-α, IFN-γ, IL-17, GM-CSF) oder B Zell- ... Diese Tatsache spricht gegen eine Autoantigen-induzierte klonale Expansion von Memory T Zellen und weist auf eine initiale ... Ein deutlicher, aber variabler Anteil der Autoantigen-spezifischen T-Zellen wies einen Memory-Phänotyp (CD45RO+) auf. Interes¬ ... und Funktionsstatus der CD4+ T-Zellen von MS-Patienten und weniger auf eine Autoantigen-spezifische Modulation schließen. Neben ...
FLNB gene: MedlinePlus Genetics
Autoantigens as Partners in Initiation and Propagation of Autoimmune Rheumatic Diseases. | Annu Rev Immunol;34: 395-420, 2016...
Autoantigens as Partners in Initiation and Propagation of Autoimmune Rheumatic Diseases.. Rosen, Antony; Casciola-Rosen, Livia ... Systemic autoimmune diseases are characterized by specific targeting of a limited group of ubiquitously expressed autoantigens ... We propose that this resonance may be a critical principle underlying disease propagation, with specific autoantigens ... Many autoantigens are components of multimolecular complexes, and some of the other components may provide adjuvant activity. ...