Highly Expressing SCARA5 Promotes Proliferation and Migration of Esophageal Squamous Cell Carcinoma
C. Soncini, P. Carpinelli, L. Gianellini et al., "PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity ... extracellular signal-regulated kinase (ERK), and adenosine monophosphate-activated protein kinase (AMPK) signaling pathways but ... and might affect cell proliferation and invasion abilities by the focal adhesion kinase (FAK) signaling pathway and epithelial- ...
Publications | www.ibmc.up.pt
Gilot David - Google Scholar
Overexpression of active Aurora-C kinase results in cell transformation and tumour formation. J Khan, F Ezan, JY Cr met, A ... Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth. GP Ilyin, D ... regulated kinases ERK1 and ERK2. C Fr min, A Bessard, F Ezan, L Gailhouste, M R geard, J Le Seyec, ... ...
Resident Publications | General Surgery Residency
Targeting aurora kinase A inhibits hypoxia-mediated neuroblastoma cell tumorigenesis.. Romain CV, Paul P, Lee S, Qiao J, Chung ... Targeting Aurora kinase-A downregulates cell proliferation and angiogenesis in neuroblastoma.. Romain C, Paul P, Kim KW, Lee S ... Differential regulation of cyclin-dependent kinase inhibitors in neuroblastoma cells.. Qiao L, Paul P, Lee S, Qiao J, Wang Y, ... B cells assist allograft rejection in the deficiency of protein kinase c-theta. ...
Description: Beyond Affinity: Drug-Kinase Interaction Put under the Microscope :: Publikationsserver
Die Regulation der N-Myc-Stabilität ist eine wichtige Funktion der Aurora-A-Kinase in MYCN- amplifizierten Neuroblastomen by: ... A kinase screen testing 16 ligands against 39 different kinases was performed in order to evaluate if thermodynamic properties ... In this thesis a model protein, namely cAMP-dependent protein kinase (PKA) is used to gain particular insights into kinase ... Beyond Affinity: Drug-Kinase Interaction Put under the Microscope Over the last 20 years, the consideration of biophysical ...
144 Targeting Bcl 2 Regulated Apoptosis In Cancer PPTs View free & download | PowerShow.com
Heterocyclic Schiff Base | K562 | Cytotoxic | Antiproliferative | Apoptosis
Mechanistic Insights into COX Irreversible Inactiv... - Page 6 - ACS Community
Publications | www.ibmc.up.pt
Research
Regulation of the V-ATPase by Aurora Kinase A (AURKA) in kidney and breast malignancies. Regulation of Aquaporin-2 (AQP2) by ... Renal Salt Transport Regulation by WNK Kinases. *Rao R, Bhalla V, Pastor-Soler NM. Intercalated Cells of the Kidney Collecting ... Regulation of Nedd4-2 by kinases. Regulation of other ion transport proteins by AMPK. AMPK activation by metformin as a novel ... Activation of AMP-activated protein kinase during sepsis/inflammation improves survival by preserving cellular metabolic ...
Search results for: '2c i hcl'
Aurora Kinase. *Sirtuins. *Epigenetic Reader Domain. *Histone Demethylases. *DNA Methyltransferases. *Histone ... inhibitor of Activin receptor-like kinase (ALK2) mutant R206H ALK2-IN-1 (BLU-782) is a potent and selective inhibitor of ... Activin receptor-like kinase (ALK2) mutant R206H with binding IC50 of Learn More ...
Researchers Implicate AURKA as a Biomarker for Bladder Cancer
Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation | eLife
2015) Aurora kinases phosphorylate Lgl to induce mitotic spindle orientation in Drosophila epithelia Current Biology 25:61-68. ... 2015) Aurora A triggers Lgl cortical release during symmetric division to control planar spindle orientation Current Biology 25 ... 2009) Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells Cell 138 ... Leucine-rich repeat kinase 2 (LRRK2) variants associated with Parkinsons disease (PD) and Crohns disease lead to increased ...
Citations - OJVM - Scientific Research Publishing
The association of RAN and RANBP2 gene polymerphisms with Wilms tumor risk in Chinese children
YRC Public Data Repository - View MS Run
WikiGenes - Breast Neoplasms
New Illumina Accelerator Start-Ups, Blood Test for Liver Cancer, Several New Collaborations, Software Offerings, More
The research team used a genetically engineered mouse model to define the role of aurora kinases in early progression of the ... March 30, 2022 , A genomic network model is used to identify aurora kinase inhibitor-sensitive lung tumors, new Illumina ... They identified and tested aurora kinase inhibitors, including AMG900, as an effective treatment to intercept lung cancer ... which often cannot be told apart via chest CT scan-and identify those that will respond to aurora kinase inhibitors, molecules ...
The Coordination between DNA Replication Initiation and Other Cell Cycle Events | IntechOpen
Aurora kinases are a family of serine-threonine protein kinases, consisting of Aurora A, Aurora B and Aurora C in mammals. ... A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function. ... The central molecular engines coordinating mitosis are a series of mitotic kinases, including CDK1/cyclin B, Aurora kinase and ... Despite the high similarity in protein sequences and structures between Aurora A and B, Aurora kinases exhibit different ...
Elín Soffía Ólafsdóttir - Prófessor | Háskóli Íslands
Daniel Reker | Scholars@Duke profile: Publications
PathScan® RP Phospho-Aurora A (Thr288) Sandwich ELISA Kit | Cell Signaling Technology
ELISA Kit for studying Aurora A (Thr288) phosphate in the research area. ... Expression of Aurora B protein also peaks during the G2/M phase of the cell cycle; Aurora B kinase activity peaks at the ... Phosphorylation of Aurora A at Thr288 in its catalytic domain increases kinase activity. Aurora A is involved in centrosome ... Aurora kinases belong to a highly conserved family of mitotic serine/threonine kinases with three members identified among ...
2019 Alumni - SPARK Research Mentorship Program - Mayo Clinic Research
6
TSC1 and TSC2 regulate cilia length and canonical Hedgehog signaling via different mechanisms | Cellular and Molecular Life...
... are involved in alternate signaling cascades including a role in WNT5A-PLK1-dependent stimulation of Aurora A kinase, leading ... Kumawat K, Menzen MH, Slegtenhorst RM et al (2014) TGF-β-activated kinase 1 (TAK1) signaling regulates TGF-β-induced WNT-5A ... Conversely, during starvation mTORC1 is inhibited and autophagy is induced by AMP-activated protein kinase (AMPK), leading to ... Christensen ST, Morthorst SK, Mogensen JB, Pedersen LB (2016) Primary cilia and coordination of receptor tyrosine kinase (RTK) ...
References on the Administration of Agents to Immunodeficient Mice Using ALZET® Osmotic Pumps - ALZET® Osmotic Pumps
Aurora kinase).. Q1168 Kioi,M., Vogel,H., Schultz,G., Hoffman,R.M., Harsh,G.R., Brown,J.M. Inhibition of vasculogenesis, but ... an Orally Bioavailable Small Molecule Aurora Kinase Inhibitor for Cancer Therapy. MOLECULAR CANCER THERAPEUTICS 2010; 9(-4-): ... ML-7; DMSO; Mice (nude); 2004; 1 week; Controls received mp w/ vehicle; enzyme inhibitor (myosin light chain kinase, MLCK); ... receptor tyrosine kinase); stress/adverse reaction: (see pg 13) "because of inflammation at the ALZET pump site, four mice of ...
Scientific production/articles during the internships - Département de Physique de l'Ecole Normale supérieure
Medical Science Monitor | Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study - Article abstract ...
... the si-Aurora-A group, and the si-Aurora-A+Drug group were significantly suppressed compared with the Normal group (P,0.01, ... the si-Aurora-A group, and the si-Aurora-A+Drug group were significantly different (P,0.01, respectively), The tumor volume and ... respectively). The positive apoptosis cell number in the Drug group, the si-Aurora-A group, and si-Aurora-A+Drug group were ... Tenacigenin B had anti-tumor effects on lymphoma via regulation of Aurora-A in vitro and in vivo. ...