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*  Determining Predictors of Safe Discontinuation of Anti-TNF Treatment in JIA - Full Text View - ClinicalTrials.gov
Polyarticular juvenile idiopathic arthritis (Poly JIA) is a form of juvenile arthritis, which is a chronic disease affecting ... Experimental: 1 Participants taking anti-TNF medications will be monitored for signs of their disease for 6 months. If, after 6 ... Arthritis, Juvenile. Arthritis. Joint Diseases. Musculoskeletal Diseases. Rheumatic Diseases. Connective Tissue Diseases. ... Approximately 30% of people with juvenile arthritis have Poly JIA.. Treatment for juvenile arthritis involves drugs with ...
https://clinicaltrials.gov/ct2/show/NCT00792233?term=TNF&rank=11
*  Experimental Arthritis Summary Report | CureHunter
Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include ... Experimental Arthritis: ARTHRITIS that is induced in experimental animals. ... Experimental Arthritis. Subscribe to New Research on Experimental Arthritis ARTHRITIS that is induced in experimental animals. ... Arthritis, Experimental; Arthritis, Adjuvant; Collagen Arthritis; Arthritides, Collagen; Arthritis, Collagen; Collagen ...
http://www.curehunter.com/public/keywordSummaryD001169-Experimental-Arthritis.do
*  Experimental arthritis drug prevents stem cell transplant complication | EurekAlert! Science News
An investigational drug in clinical trials for rheumatoid arthritis prevents a common, life-threatening side effect of stem ... experimental-arthritis-drug-prevents-stem-cell-transplant-complication/. More in Medicine & Health. * A Trojan Horse delivery ... Experimental arthritis drug prevents stem cell transplant complication Drug fights graft-versus-host-disease in mice ... Experimental arthritis drug prevents stem cell transplant complication. Washington University in St. Louis ...
https://eurekalert.org/pub_releases/2018-04/wuis-ead042418.php
*  Cardiff Regional Experimental Arthritis Treatment and Evaluation Centre (CREATE) - Research - Cardiff University
... to develop and test drugs to treat patients with Rheumatoid and Psoriatic arthritis. ... The Cardiff Regional Experimental Arthritis Treatment and Evaluation Centre works alongside volunteer patients from Cardiff and ... Protocol for a randomised controlled trial for Reducing Arthritis Fatigue by clinical Teams (RAFT) using cognitive-behavioural ... Functional analysis of a complement polymorphism (rs17611) associated with rheumatoid arthritis. The Journal of Immunology 194 ...
http://www.cardiff.ac.uk/research/explore/research-units/cardiff-regional-experimental-arthritis-treatment-and-evaluation-centre
*  JCI - Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis
Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis. ... Peptide-siRNA nanocomplexes targeting NF-κB subunit p65 suppress nascent experimental arthritis. ... The NF-κB signaling pathway is implicated in various inflammatory diseases, including rheumatoid arthritis (RA); therefore, ... The p5RHH-p65 siRNA nanocomplexes potently suppressed early inflammatory arthritis without affecting p65 expression in off- ...
https://www.jci.org/articles/view/75673/figure/1
*  Molecules | Free Full-Text | Ferulaldehyde Improves the Effect of Methotrexate in Experimental Arthritis
The aim of this study was to evaluate the effect FRA and MTX administered alone or in combination in adjuvant arthritis. The ... is still the gold standard for treatment of rheumatoid arthritis (RA). The therapeutic efficacy of low-dose of MTX can be ... rheumatoid arthritis ferulaldehyde; methotrexate; adjuvant arthritis; combination treatment; rheumatoid arthritis ... Ferulaldehyde Improves the Effect of Methotrexate in Experimental Arthritis. Lukáš Slovák 1,* , Karol Švík 1. ...
https://www.mdpi.com/1420-3049/22/11/1911
*  Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses
Arthritis induction and treatment. Animal experimental protocols were reviewed and approved by the ethics committee of the ... CST decreases the severity of collagen‐induced arthritis. CIA is a murine experimental disease model that shares a number of ... 9. Delgado M, Abad C, Martinez C, Receta J, Gomariz R P. Vasoactive intestinal peptide prevents experimental arthritis by ... Therapeutic effect of cortistatin on experimental arthritis by downregulating inflammatory and Th1 responses. Elena Gonzalez‐ ...
http://pubmedcentralcanada.ca/pmcc/articles/PMC1954632/
*  A1.69 C1Q is absolutely required for disease development in experimental arthritis | Annals of the Rheumatic Diseases
You need to be signed in to access email alerts. If you have an account log in with your user name and password. If you don't have an account you can just enter your email address in the email box below ...
http://ard.bmj.com/content/73/Suppl_1/A30.1.alerts
*  Dominant-Negative Inhibitors of Soluble TNF Attenuate Experimental Arthritis without Suppressing Innate Immunity to Infection |...
DN-TNF and decoy receptor reduce arthritis in the mouse collagen-induced arthritis model. Arthritis was induced using a 5 mg/kg ... Experimental arthritis was induced on day 0 by i.v. injection of four anti-collagen mAbs (MD Biosciences) at 25 mg/kg each ... Experimental arthritis was induced as in A and hind paw thickness (mean ± SEM) was monitored for 28 days. XENP1595 and ... CIA is another established experimental arthritis model and has been used to demonstrate anti-inflammatory activity of Ab and ...
http://www.jimmunol.org/content/179/3/1872.long
*  Suppression of Ongoing Experimental Arthritis by a Chinese Herbal Formula (Huo-Luo-Xiao-Ling Dan) Involves Changes in Antigen...
Suppression of Ongoing Experimental Arthritis by a Chinese Herbal Formula (Huo-Luo-Xiao-Ling Dan) Involves Changes in Antigen- ... F. H. Durie, R. A. Fava, and R. J. Noelle, "Collagen-induced arthritis as a model of rheumatoid arthritis," Clinical Immunology ... "Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis," Journal of ... γ regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17," Arthritis and Rheumatism, vol ...
https://www.hindawi.com/journals/ecam/2011/642027/ref/
*  Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and...
Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and ... ABMT resulted in amelioration and stabilization of arthritis scores. BM grafts containing T cells and T cell-depleted grafts ... induces long-term drug-free disease remission in patients with juvenile idiopathic arthritis. This study was undertaken to ... further unravel the immunologic mechanisms underlying ASCT by using a mouse model of proteoglycan-induced arthritis (PGIA). For ...
https://www.sigmaaldrich.com/catalog/papers/24504807
*  Effects of Low-Level Laser Therapy, 660 nm, in Experimental Septic Arthritis
... Bruna Formentão Araujo,1 Lígia Inez Silva,1 ... M. E. Shirtliff and J. T. Mader, "Acute septic arthritis," Clinical Microbiology Reviews, vol. 15, no. 4, pp. 527-544, 2002. ... Implications for joint destruction and repair," Arthritis and Rheumatism, vol. 33, no. 8, pp. 1170-1179, 1990. View at Google ... Kaya, M. Kaya, N. Gürsan, E. Kireççi, M. Güngörmüş, and H. Balta, "The use of 808 nm light therapy to treat experimental ...
https://www.hindawi.com/journals/isrn/2013/341832/ref/
*  Anti-inflammatory effects of cell-based therapy with tyrosine hydroxylase-positive catecholaminergic cells in experimental...
Conclusions The anti-inflammatory effect of TH+ neuronal cells on experimental arthritis has been presented for the first time ... Objectives Studies in rheumatoid arthritis (RA), osteoarthritis (OA) and mice with arthritis demonstrated tyrosine hydroxylase- ... inflammatory effects of cell-based therapy with tyrosine hydroxylase-positive catecholaminergic cells in experimental arthritis ... inflammatory effects of cell-based therapy with tyrosine hydroxylase-positive catecholaminergic cells in experimental arthritis ...
http://ard.bmj.com/content/74/2/444
*  AB0092 Ablation of Fc Gamma Receptors Leads To A Decreased Bone Erosion in Experimental Arthritis by Inhibiting Synovial...
AB0092 Ablation of Fc Gamma Receptors Leads To A Decreased Bone Erosion in Experimental Arthritis by Inhibiting Synovial ... AB0092 Ablation of Fc Gamma Receptors Leads To A Decreased Bone Erosion in Experimental Arthritis by Inhibiting Synovial ... Objectives To investigate the role of FcγRs in bone erosion in experimental arthritis ... 1Experimental Rheumatology, Radboud University Medical Center, Nijmegen. *. 2Human genetics, Leiden University Medical Center, ...
http://ard.bmj.com/content/75/Suppl_2/928.2
*  Suppression of ongoing experimental arthritis by a Chinese herbal formula (Huo-luo-xiao-ling dan) involves changes in antigen...
Suppression of ongoing experimental arthritis by a Chinese herbal formula (Huo-luo-xiao-ling dan) involves changes in antigen- ... Suppression of ongoing experimental arthritis by a Chinese herbal formula (Huo-luo-xiao-ling dan) involves changes in antigen- ... Suppression of ongoing experimental arthritis by a Chinese herbal formula (Huo-luo-xiao-ling dan) involves changes in antigen- ... Suppression of ongoing experimental arthritis by a Chinese herbal formula (Huo-luo-xiao-ling dan) involves changes in antigen- ...
https://dash.harvard.edu/handle/1/4874817
*  Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and Osteoclastogenesis
Clinical Scoring of Arthritis. The severity of arthritis was recorded using the mean arthritis index on scale of 0-4, as ... Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and ... It was reported that metformin ameliorated experimental autoimmune encephalitis [23] and collagen antibody induced arthritis [ ... Arthritis in these mice was examined visually two times per week for the appearance of arthritis in the peripheral joints. ...
https://www.hindawi.com/journals/mi/2014/973986/
*  Technetium-99m labelled liposomes to image experimental arthritis. - Semantic Scholar
METHODS Adjuvant arthritis was induced in the ankle joint of the left hind foot by injection of Mycobacterium butyricum in ... In addition to their use as vehicles for scintigraphic imaging of arthritis PEG-liposomes might also be used for the site ... CONCLUSION This study shows that 99mTc-labelled PEG-liposomes may be an excellent agent to visualise arthritis. Increased label ... labelled with technetium-99m were tested for their ability to image adjuvant arthritis in a rat model. ...
https://www.semanticscholar.org/paper/Technetium-99m-labelled-liposomes-to-image-Boerman-Oyen/6511bd0c64ac43923383b4816e411ba07625080f
*  Genome-wide gene expression in experimental arthritis: defining new targets of chronic/destructive rheumatoid arthritis (RA) |...
Genome-wide gene expression in experimental arthritis: defining new targets of chronic/destructive rheumatoid arthritis (RA). ... Rheumatoid Arthritis (RA) is a complex multigenic disease with yet unknown ethiology, and consequently, suitable target for ... Seventy-seven common candidates, possibly involved in sub-chronic or destructive arthritis, were defined. Many of these are ... Possible candidate genes for (sub)chronic inflammation or destructive arthritis were defined by two-parameter and cluster ...
https://arthritis-research.biomedcentral.com/articles/10.1186/ar467
*  Gene therapy with an improved doxycycline-regulated plasmid encoding a tumour necrosis factor-alpha inhibitor in experimental...
When pGTTMIK was delivered after the onset of arthritis, progression of the disease in terms of both paw thickness and clinical ... encoding dTNFR was delivered by the same route with and without administration of Dox to mice with collagen-induced arthritis. ... alpha with biological molecules has proven an effective treatment for rheumatoid arthritis, achieving a 20% improvement in ... Inhibition of collagen-induced arthritis by pGTTMIK Development of arthritis in the collagen-induced arthritis (CIA) model was ...
https://arthritis-research.biomedcentral.com/articles/10.1186/ar2113
*  Autoimmunity to type II collagen an experimental model of arthritis. | JEM
Autoimmunity to type II collagen an experimental model of arthritis.. D E Trentham, A S Townes, A H Kang ... The disease is a chronic proliferative synovitis, resembling adjuvant arthritis in rats and rheumatoid arthritis in humans. ... Journal of Experimental Medicine Sep 1977, 146 (3) 857-868; DOI: 10.1084/jem.146.3.857 ... Native type II co-lagen modified by limited pepsin digestion still produces arthritis, suggesting that type-specific ...
http://jem.rupress.org/content/146/3/857.abstract
*  Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin...
Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin ... Although the alternative pathway (AP) is known to play a key pathogenic role in models of rheumatoid arthritis, the importance ... Complement plays an important role in the pathogenesis of rheumatoid arthritis. ...
https://www.sigmaaldrich.com/catalog/papers/28739878
*  Therapeutic Effect of a Poly(ADP-Ribose) Polymerase-1 Inhibitor on Experimental Arthritis by Downregulating Inflammation and...
Polymerase-1 Inhibitor on Experimental Arthritis by Downregulating Inflammation and Th1 Response. Gonzalez_Arthritis.pdf (318.4 ... Here, we investigate the impact of a selective PARP-1 inhibitor in experimental arthritis. PARP-1 inhibition with 5- ... Therapeutic Effect of a Poly(ADP-Ribose) Polymerase-1 Inhibitor on Experimental Arthritis by Downregulating Inflammation and ... Our results provide evidence of the contribution of PARP-1 to the progression of arthritis and identify this protein as a ...
http://digibug.ugr.es/handle/10481/30951
*  Impact of IL-1 signalling on experimental uveitis and arthritis | Annals of the Rheumatic Diseases
Results Deficiency in IL-1Ra predisposes to spontaneous arthritis, which is exacerbated by previous systemic LPS exposure. The ... Objective To seek possible links between arthritis and uveitis pathogenesis related to IL-1 signalling. ... and by intravital videomicroscopy to determine if uveitis developed along with the expected spontaneous arthritis in ankles and ... eye, however, does not develop inflammatory disease despite the progressive arthritis or LPS exposure. Organ-specific ...
http://ard.bmj.com/content/early/2012/01/20/annrheumdis-2011-200556
*  Experimental approach may reverse rheumatoid arthritis and osteoporosis - ScienceBlog.com
... because they effectively prevent bone loss and inflammation in most patients with rheumatoid arthritis. They have also been ... a powerful new way to limit bone destruction and inflammation-induced bone loss seen in osteoporosis and rheumatoid arthritis ...
https://scienceblog.com/25401/experimental-approach-may-reverse-rheumatoid-arthritis-and-osteoporosis/
*  Total glucosides of paeony prevents juxta-articular bone loss in experimental arthritis | BMC Complementary and Alternative...
TGP has been used in rheumatoid arthritis therapy for many years. However, the mechanism by which TGP prevents bone loss has ... TGP was orally administered for 3 months to New Zealand rabbits with antigen-induced arthritis (AIA). Digital x-ray knee images ... Total glucosides of paeony prevents juxta-articular bone loss in experimental arthritis. ... Arthritis Res Ther. 2011, 13: 215-10.1186/ar3280.View ArticlePubMedPubMed CentralGoogle Scholar. ...
https://bmccomplementalternmed.biomedcentral.com/articles/10.1186/1472-6882-13-186