Local Tetrahydrobiopterin Administration Augments Reflex Cutaneous Vasodilation Through Nitric Oxide-Dependent Mechanisms In...
BH4 and arginase inhibition both increased vasodilation in older (BH4: 55 ± 5%; arginase-inhibited: 47 ± 5% vs. control: 37 ± 3 ... We hypothesized that acute local BH4 administration or arginase inhibition would similarly augment reflex vasodilation in aged ... hydroxy-nor-l-arginine to inhibit arginase, and 4) 20 mM NG-nitro-l-arginine methyl ester (l-NAME) to inhibit NOS. Red cell ... both P < 0.01) but not young subjects compared with control (BH4: 51 ± 4%CVCmax; arginase- inhibited: 55 ± 4%CVCmax vs. control ...
DailyMed - SODIUM PHENYLACETATE AND SODIUM BENZOATE injection
Antioxidants | Free Full-Text | Antioxidant and Anti-Inflammatory Activities of Flavanones from Glycyrrhiza glabra L. (licorice...
Human Tie-2 DuoSet ELISA DY5159: R&D Systems
Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced...
FoxP3 and arginase-1). The gating strategy used for each of the populations analyzed in this study is shown in Supplementary ... one of which includes arginine depletion via the production of the arginine-degrading enzymes arginase-1 (Arg1) and inducible ...
J. DAVID SYMONS, PhD - Research - Faculty Profile - The University of Utah
Manganese metabolism in humans
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Plasma arginase degrades arginine, the substrate for NO synthesis, thereby limiting the expected compensatory increase in NO ... Plasma arginase is also associated with pulmonary hypertension and risk of early mortality. ... and arginase into plasma. PFH has been associated with endothelial injury including scavenging nitric oxide (NO), ...
NIOSHTIC-2 Search Results - Basic View
Systemic changes in arginase and arginine metabolism in a model of atherosclerosis: a comparison of apoE-/- and C57 mice. ...
BiGG Gene 383 AT1
Former Co-Workers • Molecular Drug Design (Head: Prof. Dr. Gerhard Wolber) • Department of Biology, Chemistry, Pharmacy
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UltraLine Antibodies for Roche BenchMark XT/ULTRA
Asperosaponin VI ameliorates the CMS-induced depressive-like behaviors by inducing a neuroprotective microglial phenotype in...
TCF1 | Cancer Genetics Web
... we investigated the transcriptional regulation of arginase 1 (Arg1) and ornithine transcarbamylase (OTC) in HepG2 cells. We ...
Generation of hepatic spheroids using human hepatocyte-derived liver progenitor-like cells for hepatotoxicity screening
Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with...
Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells. Cancer ... Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion. Cancer Res. 2005;65 ... Population alterations of L-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14(-)/CD15+/CD33+ myeloid-derived ...
YRC Public Data Repository - Gene Ontology GO Protein Search Results
Abstract B026: MDSCs and CD8 effector memory T cells correlate with survival in melanoma patients treated with ipilimumab |...
Fractionated Radiation Therapy Stimulates Antitumor Immunity Mediated by Both Resident and Infiltrating Polyclonal T-cell...
Frontiers | Comparison of the Functional microRNA Expression in Immune Cell Subsets of Neonates and Adults
Collaborating with the Enemy: Function of Macrophages in the Development of Neoplastic Disease
Stimulated with this cytokine, macrophages release factors such as ROI, IL-1, IL-6, arginase, and TNF-α, that is, pro- ... strong expression of arginase-1 (its activity alters the metabolism of L-arginine into ornithine and polyamines, which results ...
2001 NIH Research Festival : Mini-Symposia 4
African basil is a potent natural treatment for men with erectile dysfunction - NaturalNews.com
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Signatures of CD8+ T cell dysfunction in AML patients and their reversibility with response to chemotherapy
Reactome | arginine + H2O => ornithine + urea ...
FLUOR DE LYS®-HDAC8 deacetylase substrate - BML-KI178 - Enzo Life Sciences